| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Kotchetkov, B Gröschel, W H Gmeiner, A A Krivtchik, E Trump, M Bitoova, J Cinatl, B Kornhuber, J Cinat. Antineoplastic activity of a novel multimeric gemcitabine-monophosphate prodrug against thyroid cancer cells in vitro. Anticancer research. vol 20. issue 5A. 2000-12-11. PMID:11062701. |
these results demonstrated that gemmp[10] is a potent cytotoxic agent that serves to induce apoptosis in association with increased fas expression in cultured thyroid cancer cell lines. |
2000-12-11 |
2023-08-12 |
Not clear |
| R L Nolsøe, O P Kristiansen, K Sangthongpitag, Z M Larsen, J Johannesen, A E Karlsen, F Pociot, J Nerup, C F Verge, T Mandrup-Poulse. Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group. Diabetologia. vol 43. issue 6. 2000-12-08. PMID:10907126. |
the human fas gene (fas) on chromosome 10q24.1 encoding a cell surface receptor involved in apoptosis was evaluated as a candidate susceptibility gene for type i (insulin-dependent) diabetes mellitus. |
2000-12-08 |
2023-08-12 |
human |
| R L Nolsøe, O P Kristiansen, K Sangthongpitag, Z M Larsen, J Johannesen, A E Karlsen, F Pociot, J Nerup, C F Verge, T Mandrup-Poulse. Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with type I diabetes mellitus. The Danish Study Group of Diabetes in Childhood and The Danish IDDM Epidemiology and Genetics Group. Diabetologia. vol 43. issue 6. 2000-12-08. PMID:10907126. |
apoptosis mediated by fas is important in maintaining peripheral self-tolerance and in down-regulating the immune response and could have a role in immune-mediated beta-cell destruction. |
2000-12-08 |
2023-08-12 |
human |
| E M Bruckheimer, N Kypriano. Apoptosis in prostate carcinogenesis. A growth regulator and a therapeutic target. Cell and tissue research. vol 301. issue 1. 2000-12-07. PMID:10928288. |
the main focus will be on the role of the transforming growth factor-beta (tgf-beta) signaling pathway, bcl-2 and the bcl-2 family members, the caspase cascade (apoptosis executioners), and the fas pathway in induction and regulation of apoptosis following therapeutic stimuli for the management of advanced prostate cancer. |
2000-12-07 |
2023-08-12 |
human |
| N Mitsiades, V Poulaki, S Tseleni-Balafouta, G P Chrousos, D A Koutra. Fas ligand expression in thyroid follicular cells from patients with thionamide-treated Graves' disease. Thyroid : official journal of the American Thyroid Association. vol 10. issue 7. 2000-12-07. PMID:10958304. |
fas ligand (fasl) induces apoptosis of susceptible cells by cross-linking its own receptor, fas. |
2000-12-07 |
2023-08-12 |
Not clear |
| F F Palazzo, L J Hammond, A W Goode, R Mirakia. Death of the autoimmune thyrocyte: is it pushed or does it jump? Thyroid : official journal of the American Thyroid Association. vol 10. issue 7. 2000-12-07. PMID:10958308. |
the mechanism of apoptosis is under the control of antiapoptotic survival genes of the bcl-2 family and proapoptotic death receptors of the tnf superfamily (fas, tnfr, trailr). |
2000-12-07 |
2023-08-12 |
Not clear |
| Y Ito, T Takeda, Y Sasaki, M Sakon, T Yamada, S Ishiguro, S Imaoka, M Tsujimoto, N Matsuur. Expression of Fas and Fas ligand reflects the biological characteristics but not the status of apoptosis of intrahepatic cholangiocellular carcinoma. International journal of molecular medicine. vol 6. issue 5. 2000-12-07. PMID:11029528. |
expression of fas and fas ligand reflects the biological characteristics but not the status of apoptosis of intrahepatic cholangiocellular carcinoma. |
2000-12-07 |
2023-08-12 |
Not clear |
| Y Ito, T Takeda, Y Sasaki, M Sakon, T Yamada, S Ishiguro, S Imaoka, M Tsujimoto, N Matsuur. Expression of Fas and Fas ligand reflects the biological characteristics but not the status of apoptosis of intrahepatic cholangiocellular carcinoma. International journal of molecular medicine. vol 6. issue 5. 2000-12-07. PMID:11029528. |
we therefore decided to investigate the status of apoptosis and of fas and fas ligand expression in this carcinoma. |
2000-12-07 |
2023-08-12 |
Not clear |
| Y Ito, T Takeda, Y Sasaki, M Sakon, T Yamada, S Ishiguro, S Imaoka, M Tsujimoto, N Matsuur. Expression of Fas and Fas ligand reflects the biological characteristics but not the status of apoptosis of intrahepatic cholangiocellular carcinoma. International journal of molecular medicine. vol 6. issue 5. 2000-12-07. PMID:11029528. |
these findings indicate that, in ccc, i) cases showing rapid growth characteristics are less likely to die of fas-mediated apoptosis and more likely to display counterattack to lymphocytes via fas ligand expressed by carcinoma cells; ii) stromal mononuclear cells express fas ligand in response to fas expression in carcinoma cells; iii) fas and fas ligand expression are not related to the status of apoptosis. |
2000-12-07 |
2023-08-12 |
Not clear |
| I Daigle, B Rückert, G Schnetzler, H U Simo. Induction of the IL-10 gene via the fas receptor in monocytes--an anti-inflammatory mechanism in the absence of apoptosis. European journal of immunology. vol 30. issue 10. 2000-12-07. PMID:11069082. |
induction of the il-10 gene via the fas receptor in monocytes--an anti-inflammatory mechanism in the absence of apoptosis. |
2000-12-07 |
2023-08-12 |
Not clear |
| I Daigle, B Rückert, G Schnetzler, H U Simo. Induction of the IL-10 gene via the fas receptor in monocytes--an anti-inflammatory mechanism in the absence of apoptosis. European journal of immunology. vol 30. issue 10. 2000-12-07. PMID:11069082. |
fas receptor-mediated transcriptional activation of the il-10 gene was followed by the release of large amounts of the cytokine in cell cultures and occurred in the absence of apoptosis induction. |
2000-12-07 |
2023-08-12 |
Not clear |
| T Chodon, T Sugihara, H H Igawa, E Funayama, H Furukaw. Keloid-derived fibroblasts are refractory to Fas-mediated apoptosis and neutralization of autocrine transforming growth factor-beta1 can abrogate this resistance. The American journal of pathology. vol 157. issue 5. 2000-12-07. PMID:11073825. |
there were no significant differences in the level of expression of fas, bcl-2, and bax between the three groups but addition of transforming growth factor (tgf)-beta1 significantly inhibited fas-mediated apoptosis in hypertrophic scar-derived and normal skin-derived fibroblasts and neutralization of autocrine tgf-beta1 with anti-tgf-beta1 antibody abrogated the resistance of keloid-derived fibroblasts. |
2000-12-07 |
2023-08-12 |
Not clear |
| V Di Martino, C Brenot, D Samuel, F Saurini, V Paradis, M Reynés, H Bismuth, C Féra. Influence of liver hepatitis C virus RNA and hepatitis C virus genotype on FAS-mediated apoptosis after liver transplantation for hepatitis C. Transplantation. vol 70. issue 9. 2000-12-07. PMID:11087158. |
we investigated the involvement of apoptosis in recurrent hcv liver disease, and its possible links with histological findings, hcv genotype, liver hcv rna level, and liver fas mrna level. |
2000-12-07 |
2023-08-12 |
Not clear |
| S Nakatsuka, T Takakuwa, Y Tomita, H Miwa, F Matsuzuka, K Aozas. Role of hypermethylation of DAP-kinase CpG island in the development of thyroid lymphoma. Laboratory investigation; a journal of technical methods and pathology. vol 80. issue 11. 2000-12-07. PMID:11092525. |
death-associated protein-kinase (dap-kinase) is a serine/threonine kinase with a death domain that is involved in apoptosis induced by interferon-gamma, tnf-alpha, and fas ligand. |
2000-12-07 |
2023-08-12 |
Not clear |
| G Egidy, L P Eberl, O Valdenaire, M Irmler, R Majdi, A C Diserens, A Fontana, R C Janzer, F Pinet, L Juillerat-Jeannere. The endothelin system in human glioblastoma. Laboratory investigation; a journal of technical methods and pathology. vol 80. issue 11. 2000-12-07. PMID:11092528. |
apoptosis was potentiated by fas ligand (apo-1l, cd95l), a pro-apoptotic peptide, only in lnz308 cells, corresponding to the known functional fas expression in these cell lines. |
2000-12-07 |
2023-08-12 |
human |
| E Yakirevich, L Maroun, O Cohen, O B Izhak, G Rennert, M B Resnic. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. The Journal of pathology. vol 192. issue 2. 2000-12-06. PMID:11004692. |
apoptosis, proliferation, and fas (apo-1, cd95)/fas ligand expression in medullary carcinoma of the breast. |
2000-12-06 |
2023-08-12 |
Not clear |
| E Yakirevich, L Maroun, O Cohen, O B Izhak, G Rennert, M B Resnic. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. The Journal of pathology. vol 192. issue 2. 2000-12-06. PMID:11004692. |
this study evaluates the extent of apoptosis in relation to fas (apo-1, cd95)/fas ligand (fasl) expression in mc. |
2000-12-06 |
2023-08-12 |
Not clear |
| E Yakirevich, L Maroun, O Cohen, O B Izhak, G Rennert, M B Resnic. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. The Journal of pathology. vol 192. issue 2. 2000-12-06. PMID:11004692. |
the observation that the majority of mcs express fas and are infiltrated by lymphocytes expressing fasl suggests that increased apoptosis in mc is mediated by fas/fasl. |
2000-12-06 |
2023-08-12 |
Not clear |
| E Yakirevich, L Maroun, O Cohen, O B Izhak, G Rennert, M B Resnic. Apoptosis, proliferation, and Fas (APO-1, CD95)/Fas ligand expression in medullary carcinoma of the breast. The Journal of pathology. vol 192. issue 2. 2000-12-06. PMID:11004692. |
however, our observation that the majority of mcs also express fasl and the fact that tumours co-expressing fas and fasl did not show increased apoptosis suggest that there may be additional cytotoxic pathways that lead to tumour apoptosis in mc. |
2000-12-06 |
2023-08-12 |
Not clear |
| A Peinnequin, A Piriou, J Mathieu, V Dabouis, C Sebbah, R Malabiau, J C Debouz. Non-thermal effects of continuous 2.45 GHz microwaves on Fas-induced apoptosis in human Jurkat T-cell line. Bioelectrochemistry (Amsterdam, Netherlands). vol 51. issue 2. 2000-12-05. PMID:10910164. |
results obtained assess non-thermal mw effects on fas, but neither on butyrate- nor on ceramide-induced apoptosis in human jurkat t-cell line. |
2000-12-05 |
2023-08-12 |
human |