| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M José de los Santos, D J Anderson, C Racowsky, J A Hil. Presence of Fas-Fas ligand system and bcl-2 gene products in cells and fluids from gonadotropin-stimulated human ovaries. Biology of reproduction. vol 63. issue 6. 2001-01-26. PMID:11090453. |
the purpose of this study was to characterize the expression of these molecules in human oocytes and cumulus cells from gonadotropin-stimulated human ovaries and to determine whether the presence of soluble fas (sfas), soluble fasl, or interferon-gamma in follicular fluid (ff) correlated with apoptosis in cumulus cells, oocyte maturation, and embryo quality. |
2001-01-26 |
2023-08-12 |
human |
| S Cappellesso, G Thibault, C Hoarau, H Watier, P Bardos, Y Lebranch. Induction of Jurkat T-cell apoptosis by Fas ligand-transfected endothelial cells. Transplantation proceedings. vol 32. issue 8. 2001-01-26. PMID:11134778. |
induction of jurkat t-cell apoptosis by fas ligand-transfected endothelial cells. |
2001-01-26 |
2023-08-12 |
Not clear |
| R Schlapbach, K S Spanaus, U Malipiero, S Lens, A Tasinato, J Tschopp, A Fontan. TGF-beta induces the expression of the FLICE-inhibitory protein and inhibits Fas-mediated apoptosis of microglia. European journal of immunology. vol 30. issue 12. 2001-01-26. PMID:11169411. |
resistance to fas-mediated apoptosis by tgf-beta does not correlate with a down-regulation of fas expression. |
2001-01-26 |
2023-08-12 |
Not clear |
| H Iwama, M Kato, S Ohmori, K Akimaru, K Tsutsumi, J Tohma, N Nakamur. Measurement of soluble Fas antigen and ligand in circulating serum and intra-abdominal or cerebrospinal fluid during gastrointestinal or cerebrovascular surgery. Journal of critical care. vol 15. issue 3. 2001-01-25. PMID:11011825. |
soluble fas antigen (sfas) and ligand (sfasl), which are associated with apoptosis, have not been evaluated in gastrointestinal or cerebrovascular surgery. |
2001-01-25 |
2023-08-12 |
Not clear |
| A I Bolstad, A Wargelius, B Nakken, H J Haga, R Jonsso. Fas and Fas ligand gene polymorphisms in primary Sjögren's syndrome. The Journal of rheumatology. vol 27. issue 10. 2001-01-25. PMID:11036836. |
to screen for polymorphisms in the apoptosis regulating fas and fas ligand (fasl) genes in patients with primary sjögren's syndrome (ss), and to explore associations with susceptibility to the disease. |
2001-01-25 |
2023-08-12 |
Not clear |
| J Song, E Sapi, W Brown, J Nilsen, K Tartaro, B M Kacinski, J Craft, F Naftolin, G Mo. Roles of Fas and Fas ligand during mammary gland remodeling. The Journal of clinical investigation. vol 106. issue 10. 2001-01-25. PMID:11086022. |
in this study, we evaluated the expression of fas and fas ligand (fasl) in the mammary gland tissue and their possible role in the induction of apoptosis of mammary cells. |
2001-01-25 |
2023-08-12 |
mouse |
| J Song, E Sapi, W Brown, J Nilsen, K Tartaro, B M Kacinski, J Craft, F Naftolin, G Mo. Roles of Fas and Fas ligand during mammary gland remodeling. The Journal of clinical investigation. vol 106. issue 10. 2001-01-25. PMID:11086022. |
increase in fas and fasl protein was demonstrated in human (mcf10a) and mouse (hc-11) mammary epithelial cells after incubation in hormone-deprived media, before apoptosis was detected. |
2001-01-25 |
2023-08-12 |
mouse |
| Y Nakai, S Irie, T A Sat. Identification of IkappaBalpha as a substrate of Fas-associated phosphatase-1. European journal of biochemistry. vol 267. issue 24. 2001-01-18. PMID:11106428. |
fas (apo-1/cd95), a member of the tumor necrosis factor receptor (tnfr)/nerve growth factor receptor (ngfr) superfamily, is a cell-surface molecule that induces apoptosis upon activation. |
2001-01-18 |
2023-08-12 |
human |
| L Schandené, F Roufosse, A de Lavareille, P Stordeur, A Efira, B Kennès, E Cogan, M Goldma. Interferon alpha prevents spontaneous apoptosis of clonal Th2 cells associated with chronic hypereosinophilia. Blood. vol 96. issue 13. 2001-01-18. PMID:11110703. |
first, these cells displayed a high rate of spontaneous apoptosis on culture in cytokine-free medium and were also sensitive to fas-mediated apoptosis induced by soluble fas ligand. |
2001-01-18 |
2023-08-12 |
Not clear |
| S K Lundy, S P Lerman, D L Boro. Soluble egg antigen-stimulated T helper lymphocyte apoptosis and evidence for cell death mediated by FasL(+) T and B cells during murine Schistosoma mansoni infection. Infection and immunity. vol 69. issue 1. 2001-01-18. PMID:11119515. |
this study investigated the dynamics of splenic and granuloma cd4(+) th cell apoptosis and fas ligand (fasl) expression during the acute and chronic stages of murine schistosomal infection. |
2001-01-18 |
2023-08-12 |
Not clear |
| J J Bleesing, S E Straus, T A Fleishe. Autoimmune lymphoproliferative syndrome. A human disorder of abnormal lymphocyte survival. Pediatric clinics of North America. vol 47. issue 6. 2001-01-18. PMID:11130997. |
the importance of fas in the homeostatic balance between lymphocyte survival and death is underscored by the three main consequences of defective fas-mediated apoptosis, as experienced by patients with alps: (1) abnormal accumulation of lymphocytes results in lymphadenopathy, hepatosplenomegaly, and hypersplenism; (2) failure of removal of potentially autoreactive lymphocytes, a process normally used to eliminate lymphocytes that have escaped negative selection in the thymus and bone marrow (see article by fleisher and blessing, p. 1197), is associated with the appearance of autoimmune manifestations; and (3) inappropriate survival of lymphocytes may lead to the development of malignancies. |
2001-01-18 |
2023-08-12 |
mouse |
| H Matsumura, Y Shimizu, Y Ohsawa, A Kawahara, Y Uchiyama, S Nagat. Necrotic death pathway in Fas receptor signaling. The Journal of cell biology. vol 151. issue 6. 2001-01-17. PMID:11121439. |
when human jurkat, or its transformants, expressing mouse fas were treated with fas ligand or anti-mouse fas antibodies, the cells died, showing characteristics of apoptosis. |
2001-01-17 |
2023-08-12 |
mouse |
| B B Whitlock, S Gardai, V Fadok, D Bratton, P M Henso. Differential roles for alpha(M)beta(2) integrin clustering or activation in the control of apoptosis via regulation of akt and ERK survival mechanisms. The Journal of cell biology. vol 151. issue 6. 2001-01-17. PMID:11121444. |
in contrast, in the presence of proapoptotic stimuli, such as fas ligation, tnfalpha, or uv irradiation, ligation of active alpha(m)beta(2) resulted in enhanced mitochondrial changes and apoptosis. |
2001-01-17 |
2023-08-12 |
Not clear |
| N Shinoura, N Yamamoto, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Japanese journal of cancer research : Gann. vol 91. issue 10. 2001-01-11. PMID:11050476. |
adenovirus-mediated transfer of fas ligand gene augments radiation-induced apoptosis in u-373mg glioma cells. |
2001-01-11 |
2023-08-12 |
Not clear |
| N Shinoura, N Yamamoto, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Japanese journal of cancer research : Gann. vol 91. issue 10. 2001-01-11. PMID:11050476. |
to override the resistance mechanism of glioma cells with p53 mutation to radiation, we transduced u-373mg malignant astrocytoma (glioma) cells harboring mutant p53 with fas ligand via an adenovirus (adv) vector in combination with x-ray irradiation, and evaluated the degree of apoptosis. |
2001-01-11 |
2023-08-12 |
Not clear |
| N Shinoura, N Yamamoto, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Japanese journal of cancer research : Gann. vol 91. issue 10. 2001-01-11. PMID:11050476. |
the degree of apoptosis in u-373mg cells infected with the adv for fas ligand (adv-fl) and treated with irradiation (81%) was much higher than that in u-373mg cells infected with adv-fl and not treated with irradiation (0.8%) or that in u-373mg cells infected with the control adv for lacz and treated with irradiation (5.0%). |
2001-01-11 |
2023-08-12 |
Not clear |
| N Shinoura, N Yamamoto, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Japanese journal of cancer research : Gann. vol 91. issue 10. 2001-01-11. PMID:11050476. |
coincident with the increase in fas ligand, there was a marked reduction in the caspase-3 level and a marked increase in the cleaved form of poly(adp-ribose) polymerase (parp), which are downstream components of fas ligand-mediated apoptosis. |
2001-01-11 |
2023-08-12 |
Not clear |
| N Shinoura, N Yamamoto, A Asai, T Kirino, H Hamad. Adenovirus-mediated transfer of Fas ligand gene augments radiation-induced apoptosis in U-373MG glioma cells. Japanese journal of cancer research : Gann. vol 91. issue 10. 2001-01-11. PMID:11050476. |
this suggests that the enhanced activation of caspase-3 by the transduction of fas ligand combined with irradiation, induced extensive apoptosis in u-373mg cells. |
2001-01-11 |
2023-08-12 |
Not clear |
| H Yoshikawa, Y Nakajima, K Tasak. Enhanced expression of Fas-associated death domain-like IL-1-converting enzyme (FLICE)-inhibitory protein induces resistance to Fas-mediated apoptosis in activated mast cells. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086061. |
though mouse mast cell line mc/9 expresses cell surface fas ag and is sensitive to fas-induced apoptosis, activated mc/9 cells are resistant to fas-induced cell death by cross-linking of fcepsilonri or fcgammar. |
2001-01-11 |
2023-08-12 |
mouse |
| H Yoshikawa, Y Nakajima, K Tasak. Enhanced expression of Fas-associated death domain-like IL-1-converting enzyme (FLICE)-inhibitory protein induces resistance to Fas-mediated apoptosis in activated mast cells. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 11. 2001-01-11. PMID:11086061. |
in this report, we show that activation of mast cells by cross-linking of fcepsilonri or fcgammar can induce enhanced expression of flip and consequently a resistance to fas-induced apoptosis, although the expression level of fas ag is not changed. |
2001-01-11 |
2023-08-12 |
mouse |