Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
W D Thomas, X D Zhang, A V Franco, T Nguyen, P Herse. TNF-related apoptosis-inducing ligand-induced apoptosis of melanoma is associated with changes in mitochondrial membrane potential and perinuclear clustering of mitochondria. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067917. |
trail, but not tnf-alpha or fas ligand, was shown to induce marked changes in mmp in melanoma, which showed a high correlation with trail-induced apoptosis. |
2000-12-22 |
2023-08-12 |
Not clear |
J Caamaño, C Tato, G Cai, E N Villegas, K Speirs, L Craig, J Alexander, C A Hunte. Identification of a role for NF-kappa B2 in the regulation of apoptosis and in maintenance of T cell-mediated immunity to Toxoplasma gondii. Journal of immunology (Baltimore, Md. : 1950). vol 165. issue 10. 2000-12-22. PMID:11067930. |
this loss of t cells correlated with increased levels of apoptosis and with elevated expression of the pro-apoptotic molecule fas by t cells from infected nf-kappab(2)(-/-) mice. |
2000-12-22 |
2023-08-12 |
mouse |
G Mor, F Kohen, J Garcia-Velasco, J Nilsen, W Brown, J Song, F Naftoli. Regulation of fas ligand expression in breast cancer cells by estrogen: functional differences between estradiol and tamoxifen. The Journal of steroid biochemistry and molecular biology. vol 73. issue 5. 2000-12-22. PMID:11070347. |
moreover, an increase in fasl in breast cancer cells induces apoptosis in fas bearing t cells and, tamoxifen blocks the induction of apoptosis. |
2000-12-22 |
2023-08-12 |
Not clear |
S Fujieda, H Sunaga, H Tsuzuki, G K Fan, T Ito, C Sugimoto, H Sait. Expression of fas (CD95) ligand is correlated with IL-10 and granulocyte colony-stimulating factor expression in oral and oropharyngeal squamous cell carcinoma. Cancer letters. vol 161. issue 1. 2000-12-22. PMID:11078915. |
in this study we investigated the expression of fas and fasl and the rate of spontaneous apoptosis in 58 oral and oropharyngeal squamous cell carcinoma (scc) by using immunohistochemical techniques. |
2000-12-22 |
2023-08-12 |
Not clear |
S Fujieda, H Sunaga, H Tsuzuki, G K Fan, T Ito, C Sugimoto, H Sait. Expression of fas (CD95) ligand is correlated with IL-10 and granulocyte colony-stimulating factor expression in oral and oropharyngeal squamous cell carcinoma. Cancer letters. vol 161. issue 1. 2000-12-22. PMID:11078915. |
the expression of fas in the tumor did not affect spontaneous apoptosis of the tumor cells. |
2000-12-22 |
2023-08-12 |
Not clear |
H Kinoshita, H Yoshikawa, K Shiiki, Y Hamada, Y Nakajima, K Tasak. Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. International journal of cancer. vol 88. issue 6. 2000-12-22. PMID:11093825. |
human osteosarcoma cell mg-63 constitutively expressed cell surface fas antigen but was resistant to apoptosis by fas stimulation. |
2000-12-22 |
2023-08-12 |
human |
H Kinoshita, H Yoshikawa, K Shiiki, Y Hamada, Y Nakajima, K Tasak. Cisplatin (CDDP) sensitizes human osteosarcoma cell to Fas/CD95-mediated apoptosis by down-regulating FLIP-L expression. International journal of cancer. vol 88. issue 6. 2000-12-22. PMID:11093825. |
however, suboptimal dose of cisplatin(cddp) could sensitize mg-63 cells to fas-mediated apoptosis without up-regulation of cell-surface fas antigen. |
2000-12-22 |
2023-08-12 |
human |
I Hara, H Miyake, S Hara, S Arakawa, S Kamidon. Differential involvement of the Fas receptor/ligand system in p53-dependent apoptosis in human prostate cancer cells. The Prostate. vol 45. issue 4. 2000-12-22. PMID:11102960. |
differential involvement of the fas receptor/ligand system in p53-dependent apoptosis in human prostate cancer cells. |
2000-12-22 |
2023-08-12 |
human |
I Hara, H Miyake, S Hara, S Arakawa, S Kamidon. Differential involvement of the Fas receptor/ligand system in p53-dependent apoptosis in human prostate cancer cells. The Prostate. vol 45. issue 4. 2000-12-22. PMID:11102960. |
the objective of this study was to characterize the involvement of the fas receptor/ligand system in p53-dependent apoptosis in human prostate cancer cells. |
2000-12-22 |
2023-08-12 |
human |
S Y Sun, P Yue, W K Hong, R Lota. Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptosis by the synthetic retinoid CD437 in human lung cancer cells. Cancer research. vol 60. issue 22. 2000-12-22. PMID:11103825. |
induction of fas expression and augmentation of fas/fas ligand-mediated apoptosis by the synthetic retinoid cd437 in human lung cancer cells. |
2000-12-22 |
2023-08-12 |
human |
S Y Sun, P Yue, W K Hong, R Lota. Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptosis by the synthetic retinoid CD437 in human lung cancer cells. Cancer research. vol 60. issue 22. 2000-12-22. PMID:11103825. |
in the present study, we investigated whether cd437 induced the expression of fas (cd95/apo-1), a cell surface protein belonging to the tumor necrosis factor receptor superfamily, which induces apoptosis upon interaction with fas ligand (fasl) or agonistic antibodies. |
2000-12-22 |
2023-08-12 |
human |
S Y Sun, P Yue, W K Hong, R Lota. Induction of Fas expression and augmentation of Fas/Fas ligand-mediated apoptosis by the synthetic retinoid CD437 in human lung cancer cells. Cancer research. vol 60. issue 22. 2000-12-22. PMID:11103825. |
taken together, these results demonstrate that increased fas expression may play an important role in cd437-induced, p53-dependent apoptosis in human nsclc cells. |
2000-12-22 |
2023-08-12 |
human |
J Shen, S Bao, V E Reev. UVA and UVB wavebands modulate expression of fasL in mouse skin epidermis. Redox report : communications in free radical research. vol 5. issue 2-3. 2000-12-21. PMID:10939301. |
in the present investigations, the effects of irradiation with uva and uvb on the fas(cd95)/fasl system have been studied because apoptosis mediated by the interaction between fas and fasl has been suggested recently to be associated with uvb-induced immunosuppression in mouse skin. |
2000-12-21 |
2023-08-12 |
mouse |
L J Pagliari, H Perlman, H Liu, R M Pop. Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis. Molecular and cellular biology. vol 20. issue 23. 2000-12-19. PMID:11073986. |
this apoptosis was independent of additional death-inducing stimuli, including fas ligation. |
2000-12-19 |
2023-08-12 |
human |
S M Quirk, R M Harman, R G Cowa. Regulation of Fas antigen (Fas, CD95)-mediated apoptosis of bovine granulosa cells by serum and growth factors. Biology of reproduction. vol 63. issue 5. 2000-12-15. PMID:11058530. |
regulation of fas antigen (fas, cd95)-mediated apoptosis of bovine granulosa cells by serum and growth factors. |
2000-12-15 |
2023-08-12 |
cattle |
S M Quirk, R M Harman, R G Cowa. Regulation of Fas antigen (Fas, CD95)-mediated apoptosis of bovine granulosa cells by serum and growth factors. Biology of reproduction. vol 63. issue 5. 2000-12-15. PMID:11058530. |
our previous studies have shown that bovine granulosa cells cultured in basal media supplemented with 5% fetal bovine serum (bm-fbs) are resistant to apoptosis induced by recombinant fas ligand (fasl) unless pretreated with interferon-gamma (ifn). |
2000-12-15 |
2023-08-12 |
cattle |
S M Quirk, R M Harman, R G Cowa. Regulation of Fas antigen (Fas, CD95)-mediated apoptosis of bovine granulosa cells by serum and growth factors. Biology of reproduction. vol 63. issue 5. 2000-12-15. PMID:11058530. |
therefore, modulation of responsiveness to fasl-induced apoptosis by growth factors and ifn is not directly related to the level of fas expression. |
2000-12-15 |
2023-08-12 |
cattle |
A Uek. [Fas-Fas ligand system in silicosis patients]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 55. issue 2. 2000-12-13. PMID:10981180. |
sfas instead of membranous fas binds competitively to the fas ligand, and consequently, reduces the apoptosis of fas positive cells. |
2000-12-13 |
2023-08-12 |
human |
J O'Connell, M W Bennett, K Nally, G C O'Sullivan, J K Collins, F Shanaha. Interferon-gamma sensitizes colonic epithelial cell lines to physiological and therapeutic inducers of colonocyte apoptosis. Journal of cellular physiology. vol 185. issue 3. 2000-12-13. PMID:11056003. |
these apoptosis inducers included fas (cd95/apo-1) ligand (fasl), short-chain fatty acids, and chemotherapeutic drugs. |
2000-12-13 |
2023-08-12 |
Not clear |
T S Zheng, S Hunot, K Kuida, T Momoi, A Srinivasan, D W Nicholson, Y Lazebnik, R A Flavel. Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nature medicine. vol 6. issue 11. 2000-12-12. PMID:11062535. |
hepatocyte apoptosis and mouse death induced by the fas agonistic antibody jo2 required proapoptotic bcl-2 family member bid and used a bid-mediated mitochondrial pathway of caspase activation; deficiency in caspases essential for this pathway, caspase-9 or caspase-3, unexpectedly resulted in rapid activation of alternate caspases after injection of jo2, and therefore failed to protect mice against jo2 toxicity. |
2000-12-12 |
2023-08-12 |
mouse |