| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M G Alvarez, C Marty, G Mori, V Rivarol. Effects of alpha-difluoromethylornithine on the Fas expression and apoptosis in Hep-2 cells. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 24. issue 3. 2001-02-22. PMID:11201656. |
effects of alpha-difluoromethylornithine on the fas expression and apoptosis in hep-2 cells. |
2001-02-22 |
2023-08-12 |
Not clear |
| M G Alvarez, C Marty, G Mori, V Rivarol. Effects of alpha-difluoromethylornithine on the Fas expression and apoptosis in Hep-2 cells. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 24. issue 3. 2001-02-22. PMID:11201656. |
fas is a type i membrane protein with a molecular mass of 45 kda, which mediates apoptosis. |
2001-02-22 |
2023-08-12 |
Not clear |
| M G Alvarez, C Marty, G Mori, V Rivarol. Effects of alpha-difluoromethylornithine on the Fas expression and apoptosis in Hep-2 cells. Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al. vol 24. issue 3. 2001-02-22. PMID:11201656. |
the results suggest that the treatment with the polyamine inhibitor dfmo induced the expression of the surface antigen fas, which could be responsible for trigger apoptosis in these cells. |
2001-02-22 |
2023-08-12 |
Not clear |
| N Mitsiades, W H Yu, V Poulaki, M Tsokos, I Stamenkovi. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer research. vol 61. issue 2. 2001-02-22. PMID:11212252. |
the ensuing engagement of fas by fasl on adjacent cells leads to apoptosis. |
2001-02-22 |
2023-08-12 |
Not clear |
| N Mitsiades, W H Yu, V Poulaki, M Tsokos, I Stamenkovi. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. Cancer research. vol 61. issue 2. 2001-02-22. PMID:11212252. |
doxorubicin-induced apoptosis was inhibited by expression of soluble fas or incubation of the tumor cells with mmp-7 but not with mmp-2 or mmp-9. |
2001-02-22 |
2023-08-12 |
Not clear |
| H Yoshida-Kato, K Ichikawa, J Yamaguchi, K Watanabe, J Ohsumi, S Yonehara, N Serizaw. Cloning and expression of a novel murine anti-human Fas antibody. Bioscience, biotechnology, and biochemistry. vol 64. issue 9. 2001-02-15. PMID:11055394. |
agonistic anti-human fas antibodies that can induce apoptosis are thought to have therapeutic effects for various diseases resulting from an abnormality of the fas/fasl system. |
2001-02-15 |
2023-08-12 |
mouse |
| M K Tietze, T Wuestefeld, Y Paul, L Zender, C Trautwein, M P Manns, S Kubick. IkappaBalpha gene therapy in tumor necrosis factor-alpha- and chemotherapy-mediated apoptosis of hepatocellular carcinomas. Cancer gene therapy. vol 7. issue 10. 2001-02-15. PMID:11059688. |
to elucidate the different role of nfkappab in chemotherapy-induced apoptosis, we investigated the expression of fas (cd95) and fas ligand (cd95 ligand), which have been described as important mediators of chemotherapy-induced cell death and as target genes of nfkappab. |
2001-02-15 |
2023-08-12 |
Not clear |
| A Elnemr, T Ohta, A Yachie, M Kayahara, H Kitagawa, I Ninomiya, S Fushida, T Fujimura, G Nishimura, K Shimizu, K Miw. Human pancreatic cancer cells express non-functional Fas receptors and counterattack lymphocytes by expressing Fas ligand; a potential mechanism for immune escape. International journal of oncology. vol 18. issue 1. 2001-02-15. PMID:11115536. |
in addition, by testing fas function using anti-fas antibody (ch11), all cell lines were resistant to fas-mediated apoptosis except capan-1 cells which showed sensitivity similar to that of jurkat t cells. |
2001-02-15 |
2023-08-12 |
human |
| E Levi, Z Wang, T Petrogiannis-Haliotis, W M Pfeifer, W Kempf, R Drews, M E Kadi. Distinct effects of CD30 and Fas signaling in cutaneous anaplastic lymphomas: a possible mechanism for disease progression. The Journal of investigative dermatology. vol 115. issue 6. 2001-02-15. PMID:11121138. |
activation of the fas pathway induced apoptosis in all three cell lines. |
2001-02-15 |
2023-08-12 |
Not clear |
| N Ahmad, S Gupta, D K Feyes, H Mukhta. Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells. The Journal of investigative dermatology. vol 115. issue 6. 2001-02-15. PMID:11121139. |
involvement of fas (apo-1/cd-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma a431 cells. |
2001-02-15 |
2023-08-12 |
human |
| N Ahmad, S Gupta, D K Feyes, H Mukhta. Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells. The Journal of investigative dermatology. vol 115. issue 6. 2001-02-15. PMID:11121139. |
in this study, employing human epidermoid carcinoma (a431) cells and silicon phthalocyanine 4 photodynamic therapy, we show that the cell surface death receptor fas (also known as apo-1 or cd-95) pathway is an important contributor to photodynamic-therapy-mediated apoptosis. |
2001-02-15 |
2023-08-12 |
human |
| N Ahmad, S Gupta, D K Feyes, H Mukhta. Involvement of Fas (APO-1/CD-95) during photodynamic-therapy-mediated apoptosis in human epidermoid carcinoma A431 cells. The Journal of investigative dermatology. vol 115. issue 6. 2001-02-15. PMID:11121139. |
taken together, our data, for the first time, delineate an involvement of the fas pathway as an important contributor to photodynamic-therapy-mediated apoptosis of cancer cells. |
2001-02-15 |
2023-08-12 |
human |
| M Ohlsson, K Skarstein, A I Bolstad, A C Johannessen, R Jonsso. Fas-induced apoptosis is a rare event in Sjögren's syndrome. Laboratory investigation; a journal of technical methods and pathology. vol 81. issue 1. 2001-02-15. PMID:11204278. |
immunohistochemistry and the terminal deoxynucleotidyl transferase mediated dutp digoxigenin nick end labeling (tunel) method were applied to study the fas and fasl expression and the incidence of apoptosis in salivary glands (sg) from patients with primary and secondary ss, af, and controls. |
2001-02-15 |
2023-08-12 |
Not clear |
| T H Kim, Y Zhao, M J Barber, D K Kuharsky, X M Yi. Bid-induced cytochrome c release is mediated by a pathway independent of mitochondrial permeability transition pore and Bax. The Journal of biological chemistry. vol 275. issue 50. 2001-02-08. PMID:10982793. |
indeed, inhibition of permeability transition did not suppress the activity of tbid in vitro nor could they block fas activation-induced, bid-dependent hepatocyte apoptosis in cultures. |
2001-02-08 |
2023-08-12 |
mouse |
| L Qiao, G C Farrel. Reciprocal control of apoptosis and proliferation in cultured rat hepatoma arl-6 cells: roles of nutrient supply, serum, and oxidative stress. In vitro cellular & developmental biology. Animal. vol 36. issue 7. 2001-02-08. PMID:11039496. |
proteolytic cleavage of poly(adp-ribose)polymerase and expression of bax are likely to be mechanistically involved with the control of spontaneous apoptosis in arl-6 cells, whereas changes in the levels of fas and bcl-2 do not play a role. |
2001-02-08 |
2023-08-12 |
rat |
| K A Browne, R W Johnstone, D A Jans, J A Trapan. Filamin (280-kDa actin-binding protein) is a caspase substrate and is also cleaved directly by the cytotoxic T lymphocyte protease granzyme B during apoptosis. The Journal of biological chemistry. vol 275. issue 50. 2001-02-08. PMID:11050075. |
filamin staining was redistributed from the cell membrane into the cytoplasm of jurkat cells exposed to granzyme b and perforin and following ligation of fas receptors, coincident with the morphological changes of apoptosis. |
2001-02-08 |
2023-08-12 |
human |
| Y Higami, K Tanaka, T Tsuchiya, I Shimokaw. Intravenous injection of cycloheximide induces apoptosis and up-regulates p53 and Fas receptor expression in the rat liver in vivo. Mutation research. vol 457. issue 1-2. 2001-02-08. PMID:11106802. |
intravenous injection of cycloheximide induces apoptosis and up-regulates p53 and fas receptor expression in the rat liver in vivo. |
2001-02-08 |
2023-08-12 |
rat |
| Y Higami, K Tanaka, T Tsuchiya, I Shimokaw. Intravenous injection of cycloheximide induces apoptosis and up-regulates p53 and Fas receptor expression in the rat liver in vivo. Mutation research. vol 457. issue 1-2. 2001-02-08. PMID:11106802. |
since the time course of increased proportion of apoptotic hepatocytes does not parallel that of p53- or fas receptor-positive hepatocytes and apoptotic hepatocytes appeared prior to up-regulation of p53 and fas receptor expression, it is likely that the enhanced expression of p53 and fas receptor is not involved directly in chx-induced apoptosis of hepatocytes in vivo. |
2001-02-08 |
2023-08-12 |
rat |
| S Ohno, M Tachibana, M Shibakita, D K Dhar, H Yoshimura, S Kinugasa, H Kubota, R Masunaga, N Nagasu. Prognostic significance of Fas and Fas ligand system-associated apoptosis in gastric cancer. Annals of surgical oncology. vol 7. issue 10. 2001-02-08. PMID:11129423. |
prognostic significance of fas and fas ligand system-associated apoptosis in gastric cancer. |
2001-02-08 |
2023-08-12 |
Not clear |
| D Kwon, C Choi, J Lee, K O Kim, J D Kim, S J Kim, I H Cho. Hydrogen peroxide triggers the expression of Fas/FasL in astrocytoma cell lines and augments apoptosis. Journal of neuroimmunology. vol 113. issue 1. 2001-02-08. PMID:11137571. |
our findings suggest up-regulation of fas in astrocytoma cells may lead them to be sensitive to apoptosis when cells are in oxidative stress. |
2001-02-08 |
2023-08-12 |
Not clear |