| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R H Unger, Y T Zho. Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover. Diabetes. vol 50 Suppl 1. 2001-04-05. PMID:11272168. |
this provides a source of excess fas that enter potentially toxic pathways of nonoxidative metabolism leading to apoptosis of certain tissues. |
2001-04-05 |
2023-08-12 |
Not clear |
| P R Walker, T Calzascia, V Schnuriger, D Chalmers, P Saas, P Y Dietric. Loss of Fas (CD95/APO-1) expression by antigen-specific cytotoxic T cells is reversed by inhibiting DNA methylation. Cellular immunology. vol 206. issue 1. 2001-03-29. PMID:11161437. |
elimination of clonally expanded peripheral cd8 t cells was thought to involve apoptosis induction mediated principally by tnf, but recently fas (cd95/apo-1) has been shown to play a role in certain responses. |
2001-03-29 |
2023-08-12 |
Not clear |
| J H Lin, G Deng, Q Huang, J Morse. KIAP, a novel member of the inhibitor of apoptosis protein family. Biochemical and biophysical research communications. vol 279. issue 3. 2001-03-29. PMID:11162435. |
in addition, we show that overexpression of kiap enhances apoptosis induced by etoposide, and, that kiap fails to block apoptosis induced by overexpression of fas. |
2001-03-29 |
2023-08-12 |
human |
| C Agostini, M Siviero, M Facco, D Carollo, G Binotto, A Tosoni, A M Cattelan, R Zambello, L Trentin, G Semenzat. Antiapoptotic effects of IL-15 on pulmonary Tc1 cells of patients with human immunodeficiency virus infection. American journal of respiratory and critical care medicine. vol 163. issue 2. 2001-03-29. PMID:11179127. |
interestingly, we found a direct relationship between the predisposition to undergo spontaneous apoptosis and the levels of fas expression by bal t cells. |
2001-03-29 |
2023-08-12 |
human |
| C S Hirsch, Z Toossi, J L Johnson, H Luzze, L Ntambi, P Peters, M McHugh, A Okwera, M Joloba, P Mugyenyi, R D Mugerwa, P Terebuh, J J Ellne. Augmentation of apoptosis and interferon-gamma production at sites of active Mycobacterium tuberculosis infection in human tuberculosis. The Journal of infectious diseases. vol 183. issue 5. 2001-03-29. PMID:11181155. |
immunoreactivities of molecules potentially involved in apoptosis, such as tumor necrosis factor-alpha, fas-ligand, and fas, were increased in pleural fluid, compared with plasma. |
2001-03-29 |
2023-08-12 |
human |
| T L Rothstei. Inducible resistance to Fas-mediated apoptosis in B cells. Cell research. vol 10. issue 4. 2001-03-29. PMID:11191348. |
apoptosis produced in b cells through fas (apo-1, cd95) triggering is regulated by signals derived from other surface receptors: cd40 engagement produces upregulation of fas expression and marked susceptibility to fas-induced cell death, whereas antigen receptor engagement, or il-4r engagement, inhibits fas killing and in so doing induces a state of fas-resistance, even in otherwise sensitive, cd40-stimulated targets. |
2001-03-29 |
2023-08-12 |
Not clear |
| T L Rothstei. Inducible resistance to Fas-mediated apoptosis in B cells. Cell research. vol 10. issue 4. 2001-03-29. PMID:11191348. |
terminal effectors of b cell fas-resistance include the known anti-apoptotic gene products, bcl-xl and flip, and a novel anti-apoptotic gene that encodes faim (fas apoptosis inhibitory molecule). |
2001-03-29 |
2023-08-12 |
Not clear |
| M Nakazawa, T Nakajima, K Nishiok. [Possible pathogenesis of rheumatoid arthritis]. Nihon rinsho. Japanese journal of clinical medicine. vol 59. issue 1. 2001-03-29. PMID:11197846. |
our previous results showed that rheumatoid synoviocytes expressed fas ligand and were induced apoptosis by anti-fas antibody treatment. |
2001-03-29 |
2023-08-12 |
Not clear |
| A A Kapasi, S Fan, P C Singha. Role of 14-3-3epsilon, c-Myc/Max, and Akt phosphorylation in HIV-1 gp 120-induced mesangial cell proliferation. American journal of physiology. Renal physiology. vol 280. issue 2. 2001-03-29. PMID:11208609. |
at a higher concentration, gp 120 not only promoted hmc apoptosis but also enhanced expression of fas and fasl. |
2001-03-29 |
2023-08-12 |
human |
| G Zehender, S Varchetta, C De Maddalena, C Colasante, A Riva, L Meroni, M Moroni, M Gall. Resistance to Fas-mediated apoptosis of human T-cell lines expressing human T-lymphotropic virus type-2 (HTLV-2) Tax protein. Virology. vol 281. issue 1. 2001-03-29. PMID:11222094. |
fas-mediated apoptosis was significantly reduced in the htlv-1- and htlv-2-infected lines in comparison with the htlv-free lines regardless of the surface expression of fas antigen (which was no different in the infected and uninfected cells). |
2001-03-29 |
2023-08-12 |
human |
| G Zehender, S Varchetta, C De Maddalena, C Colasante, A Riva, L Meroni, M Moroni, M Gall. Resistance to Fas-mediated apoptosis of human T-cell lines expressing human T-lymphotropic virus type-2 (HTLV-2) Tax protein. Virology. vol 281. issue 1. 2001-03-29. PMID:11222094. |
fas-mediated apoptosis was also significantly inhibited in jurkat cells transfected with the tax-2 expressing vector without any modification in fas expression. |
2001-03-29 |
2023-08-12 |
human |
| A Hayakawa, T Kojima, I Yokoyama, H Suzuki, H Tajiri, I Nakashim. A short peptide derived from the antisense homology box of Fas ligand induces apoptosis in anti-Fas antibody-insensitive human ovarian cancer cells. Apoptosis : an international journal on programmed cell death. vol 5. issue 1. 2001-03-29. PMID:11227489. |
a short peptide derived from the antisense homology box of fas ligand induces apoptosis in anti-fas antibody-insensitive human ovarian cancer cells. |
2001-03-29 |
2023-08-12 |
human |
| V Vlaeminck-Guillem, M d'Herbomez-Boidein, M Decoulx, J L Wémea. [Apoptosis and the thyroid: the Fas pathway]. Presse medicale (Paris, France : 1983). vol 30. issue 2. 2001-03-29. PMID:11244819. |
[apoptosis and the thyroid: the fas pathway]. |
2001-03-29 |
2023-08-12 |
Not clear |
| V Vlaeminck-Guillem, M d'Herbomez-Boidein, M Decoulx, J L Wémea. [Apoptosis and the thyroid: the Fas pathway]. Presse medicale (Paris, France : 1983). vol 30. issue 2. 2001-03-29. PMID:11244819. |
the control of thyroid gland volume results from an equilibrium between the trophic action of tsh and thyrocyte apoptosis, which is limited to some extent by resistance to fas activation by producing an inhibitor of the apoptotic signal transduction. |
2001-03-29 |
2023-08-12 |
Not clear |
| V Vlaeminck-Guillem, M d'Herbomez-Boidein, M Decoulx, J L Wémea. [Apoptosis and the thyroid: the Fas pathway]. Presse medicale (Paris, France : 1983). vol 30. issue 2. 2001-03-29. PMID:11244819. |
fas and hashimoto's thyroiditis: aberrant expression of fas-l by thyrocytes induces their fratricide apoptosis. |
2001-03-29 |
2023-08-12 |
Not clear |
| V Vlaeminck-Guillem, M d'Herbomez-Boidein, M Decoulx, J L Wémea. [Apoptosis and the thyroid: the Fas pathway]. Presse medicale (Paris, France : 1983). vol 30. issue 2. 2001-03-29. PMID:11244819. |
fas and graves' disease: autoantibody-dependant stimulation of the thyrotropin receptor favors goiter formation by reducing thyrocyte apoptosis. |
2001-03-29 |
2023-08-12 |
Not clear |
| V Vlaeminck-Guillem, M d'Herbomez-Boidein, M Decoulx, J L Wémea. [Apoptosis and the thyroid: the Fas pathway]. Presse medicale (Paris, France : 1983). vol 30. issue 2. 2001-03-29. PMID:11244819. |
fas and thyroid cancer: tumoral cells are resistant to apoptosis by inhibiting the apoptotic signal transduction and exert fas counter-attack by inducing apoptosis of antitumoral lymphocytes. |
2001-03-29 |
2023-08-12 |
Not clear |
| J N Li, M Gorospe, F J Chrest, T S Kumaravel, M K Evans, W F Han, E S Pize. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer research. vol 61. issue 4. 2001-03-29. PMID:11245456. |
rko colon carcinoma cells were selected for study because they undergo little apoptosis within the first 24 h after fas inhibition. |
2001-03-29 |
2023-08-12 |
human |
| J N Li, M Gorospe, F J Chrest, T S Kumaravel, M K Evans, W F Han, E S Pize. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer research. vol 61. issue 4. 2001-03-29. PMID:11245456. |
p53 function is probably important in protecting rko cells from fas inhibition because, similar to many other tumor lines, rko cells expressing a dominant negative mutant p53 gene underwent extensive apoptosis within 24 h after fas inhibition. |
2001-03-29 |
2023-08-12 |
human |
| J N Li, M Gorospe, F J Chrest, T S Kumaravel, M K Evans, W F Han, E S Pize. Pharmacological inhibition of fatty acid synthase activity produces both cytostatic and cytotoxic effects modulated by p53. Cancer research. vol 61. issue 4. 2001-03-29. PMID:11245456. |
whereas induction of apoptosis appeared related to accumulation of the substrate, malonyl-coa, after fas inhibition, the cytostatic effects were independent of malonyl-coa accumulation and may have resulted from product depletion. |
2001-03-29 |
2023-08-12 |
human |