| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A C Loweth, K Watts, S C McBain, G T Williams, J H Scarpello, N G Morga. Dissociation between Fas expression and induction of apoptosis in human islets of Langerhans. Diabetes, obesity & metabolism. vol 2. issue 1. 2001-04-26. PMID:11220355. |
dissociation between fas expression and induction of apoptosis in human islets of langerhans. |
2001-04-26 |
2023-08-12 |
human |
| A C Loweth, K Watts, S C McBain, G T Williams, J H Scarpello, N G Morga. Dissociation between Fas expression and induction of apoptosis in human islets of Langerhans. Diabetes, obesity & metabolism. vol 2. issue 1. 2001-04-26. PMID:11220355. |
one mechanism by which this has been proposed to occur involves up-regulation of the death receptor fas on beta-cells, resulting in apoptosis of the fas-bearing beta-cells upon ligation of the receptor. |
2001-04-26 |
2023-08-12 |
human |
| A C Loweth, K Watts, S C McBain, G T Williams, J H Scarpello, N G Morga. Dissociation between Fas expression and induction of apoptosis in human islets of Langerhans. Diabetes, obesity & metabolism. vol 2. issue 1. 2001-04-26. PMID:11220355. |
we have examined this hypothesis in isolated human islets of langerhans and show that--in contrast to data obtained with rodent beta-cells--expression of fas per se is not sufficient to allow induction of apoptosis upon addition of agonistic anti-fas serum. |
2001-04-26 |
2023-08-12 |
human |
| M A Pahlavani, D A Varga. Aging but not dietary restriction alters the activation-induced apoptosis in rat T cells. FEBS letters. vol 491. issue 1-2. 2001-04-26. PMID:11226431. |
t cells were incubated with anti-cd3 antibody, or staphylococcal enterotoxin b (primary stimulus) for 72-96 h, followed by restimulation with anti-cd3 (secondary stimulus) for 72 h. activation-induced apoptosis was assessed by dna fragmentation and the expression of fas/cd95 receptor and fas ligand (fas-l) was measured by flow cytometry. |
2001-04-26 |
2023-08-12 |
rat |
| N Droin, F Bichat, C Rébé, A Wotawa, O Sordet, A Hammann, R Bertrand, E Solar. Involvement of caspase-2 long isoform in Fas-mediated cell death of human leukemic cells. Blood. vol 97. issue 6. 2001-04-26. PMID:11238127. |
engagement of the plasma membrane receptor fas can induce apoptosis of leukemic cells. |
2001-04-26 |
2023-08-12 |
human |
| C Bäumler, G O Kim, K B Elko. Growth regulation of activated lymphocytes: defects in homeostasis lead to autoimmunity and/or lymphoma. Reviews in immunogenetics. vol 2. issue 2. 2001-04-26. PMID:11258424. |
we discuss how cell death stimuli signal either the intrinsic, mitochondrial pathway of apoptosis or kill the cell through one of the six death receptors such as fas (apo-1/cd95). |
2001-04-26 |
2023-08-12 |
Not clear |
| S H Lee, M S Shin, H S Lee, J H Bae, H K Lee, H S Kim, S Y Kim, J J Jang, M Joo, Y K Kang, W S Park, J Y Park, R R Oh, S Y Han, J H Lee, S H Kim, J Y Lee, N J Yo. Expression of Fas and Fas-related molecules in human hepatocellular carcinoma. Human pathology. vol 32. issue 3. 2001-04-26. PMID:11274632. |
our results showed that the majority of the hccs (88%) coexpressed a death receptor, fas and its cognate ligand, fasl, but all hccs showed one or more alterations of the fas pathway molecules known to inhibit fas-mediated apoptosis. |
2001-04-26 |
2023-08-12 |
human |
| G Dorothee, M Ameyar, A Bettaieb, I Vergnon, H Echchakir, M Bouziane, S Chouaib, F Mami-Chouai. Role of Fas and granule exocytosis pathways in tumor-infiltrating T lymphocyte-induced apoptosis of autologous human lung-carcinoma cells. International journal of cancer. vol 91. issue 6. 2001-04-26. PMID:11275978. |
role of fas and granule exocytosis pathways in tumor-infiltrating t lymphocyte-induced apoptosis of autologous human lung-carcinoma cells. |
2001-04-26 |
2023-08-12 |
human |
| R A DeAngelis, K Kovalovich, D E Cressman, R Tau. Normal liver regeneration in p50/nuclear factor kappaB1 knockout mice. Hepatology (Baltimore, Md.). vol 33. issue 4. 2001-04-26. PMID:11283856. |
after injection of fas antibody, p50(-/-) livers showed an earlier onset of nuclear changes consistent with apoptosis. |
2001-04-26 |
2023-08-12 |
mouse |
| Y Chen, X Xu, S Hong, J Chen, N Liu, C B Underhill, K Creswell, L Zhan. RGD-Tachyplesin inhibits tumor growth. Cancer research. vol 61. issue 6. 2001-04-26. PMID:11289111. |
western blotting showed that treatment of cells with rgd-tachyplesin could activate caspase 9, caspase 8, and caspase 3 and increase the expression of the fas ligand, fas-associated death domain, caspase 7, and caspase 6, suggesting that apoptotic molecules related to both mitochondrial and fas-dependent pathways are involved in the induction of apoptosis. |
2001-04-26 |
2023-08-12 |
mouse |
| N Mitsiades, V Poulaki, C Mitsiades, M Tsoko. Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5. Cancer research. vol 61. issue 6. 2001-04-26. PMID:11289151. |
nine of 10 esft cell lines, including several that were fas resistant, underwent apoptosis with trail through activation of caspase-10, capase-8 (flice), caspase-3, and caspase-9. |
2001-04-26 |
2023-08-12 |
mouse |
| R Ciccocioppo, A Di Sabatino, R Parroni, P Muzi, S D'Alò, T Ventura, M A Pistoia, M G Cifone, G R Corazz. Increased enterocyte apoptosis and Fas-Fas ligand system in celiac disease. American journal of clinical pathology. vol 115. issue 4. 2001-04-26. PMID:11293896. |
endoscopic duodenal biopsy specimens from 12 patients with untreated and 12 with treated cd and 12 control subjects were evaluated for enterocyte apoptosis by the terminal deoxynucleotidyl transferase-mediated digoxigenin-deoxyuridine triphosphate nick-end labeling assay and for fas and fasl expression by immunohistochemistry. |
2001-04-26 |
2023-08-12 |
human |
| M Shibakita, M Tachibana, D K Dhar, S Ohno, H Kubota, H Yoshimura, S Kinugasa, R Masunaga, N Nagasu. Spontaneous apoptosis in advanced esophageal carcinoma: its relation to Fas expression. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 6. issue 12. 2001-04-19. PMID:11156230. |
spontaneous apoptosis in advanced esophageal carcinoma: its relation to fas expression. |
2001-04-19 |
2023-08-12 |
Not clear |
| M Shibakita, M Tachibana, D K Dhar, S Ohno, H Kubota, H Yoshimura, S Kinugasa, R Masunaga, N Nagasu. Spontaneous apoptosis in advanced esophageal carcinoma: its relation to Fas expression. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 6. issue 12. 2001-04-19. PMID:11156230. |
the prognostic importance of spontaneous apoptosis and its correlation with clinicopathological characteristics and fas expression have yet to be delineated in esophageal carcinoma. |
2001-04-19 |
2023-08-12 |
Not clear |
| M Shibakita, M Tachibana, D K Dhar, S Ohno, H Kubota, H Yoshimura, S Kinugasa, R Masunaga, N Nagasu. Spontaneous apoptosis in advanced esophageal carcinoma: its relation to Fas expression. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 6. issue 12. 2001-04-19. PMID:11156230. |
specimens from 65 patients with advanced squamous cell carcinoma of the esophagus were used for immunohistochemical evaluation of fas, proliferating cell nuclear antigen, and apoptosis. |
2001-04-19 |
2023-08-12 |
Not clear |
| T Ichikura, T Majima, T Uchida, E Okura, T Ogawa, H Mochizuk. Plasma soluble Fas ligand concentration: decrease in elderly men and increase in patients with gastric carcinoma. Oncology reports. vol 8. issue 2. 2001-04-19. PMID:11182046. |
fas ligand (fasl), which induces apoptosis against fas-expressing cells, has been found to be expressed on various cell types including cancer cells. |
2001-04-19 |
2023-08-12 |
human |
| H Seeberger, C Knörr, H K Müller-Hermelink, A Greine. [Impaired CD95-(Fas,APO-1-)apoptosis regulation is a progression factor in early MALT-type lymphoma genesis]. Medizinische Klinik (Munich, Germany : 1983). vol 96. issue 1. 2001-04-19. PMID:11210492. |
[impaired cd95-(fas,apo-1-)apoptosis regulation is a progression factor in early malt-type lymphoma genesis]. |
2001-04-19 |
2023-08-12 |
Not clear |
| F Silvestris, M Tucci, P Cafforio, F Dammacc. Fas-L up-regulation by highly malignant myeloma plasma cells: role in the pathogenesis of anemia and disease progression. Blood. vol 97. issue 5. 2001-04-19. PMID:11222356. |
by measuring fas and fas-l in plasma cells and erythroblasts from 19 mm patients and 5 with monoclonal gammopathies of undetermined significance (mgus), it was found that both fas-l(+) myeloma cells and fas(+) erythroid progenitors were significantly increased in patients with stage iii mm whose erythroblasts, cultured in the presence of autologous plasma cells or their supernatant, underwent prompt apoptosis as evaluated by propidium iodide staining, the tunel assay, and detection of the apo2.7-reactive mitochondrial antigen. |
2001-04-19 |
2023-08-12 |
Not clear |
| D C Thomis, S Marktel, C Bonini, C Traversari, M Gilman, C Bordignon, T Clackso. A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease. Blood. vol 97. issue 5. 2001-04-19. PMID:11222367. |
however, they rapidly underwent apoptosis with the addition of subnanomolar concentrations of ap1903, a bivalent "dimerizer" drug that binds fkbp and induces fas cross-linking. |
2001-04-19 |
2023-08-12 |
human |
| H Zeng, X Zhao, Y M. [Retinoic acid inducing Fas expression in HL-60 cells]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 19. issue 5. 2001-04-19. PMID:11243119. |
to investigate the effect of all-trans retinoic acid (atra) and 9-cis retinoic acid (9-cis ra) on the expression of fas and the sensitivity to anti-fas induced apoptosis in hl-60 cells. |
2001-04-19 |
2023-08-12 |
Not clear |