| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P R Webb, K Q Wang, D Scheel-Toellner, J Pongracz, M Salmon, J M Lor. Regulation of neutrophil apoptosis: a role for protein kinase C and phosphatidylinositol-3-kinase. Apoptosis : an international journal on programmed cell death. vol 5. issue 5. 2001-03-29. PMID:11256888. |
spontaneous neutrophil apoptosis does not require fas ligation, but is mediated by caspases 3, 8 and possibly caspase 9 and also involves activation of protein kinase c-delta. |
2001-03-29 |
2023-08-12 |
Not clear |
| M L Colamussi, P Secchiero, A Gonelli, M Marchisio, G Zauli, S Capitan. Stromal derived factor-1 alpha (SDF-1 alpha) induces CD4+ T cell apoptosis via the functional up-regulation of the Fas (CD95)/Fas ligand (CD95L) pathway. Journal of leukocyte biology. vol 69. issue 2. 2001-03-29. PMID:11272277. |
stromal derived factor-1 alpha (sdf-1 alpha) induces cd4+ t cell apoptosis via the functional up-regulation of the fas (cd95)/fas ligand (cd95l) pathway. |
2001-03-29 |
2023-08-12 |
Not clear |
| I Petak, L Douglas, D M Tillman, R Vernes, J A Houghto. Pediatric rhabdomyosarcoma cell lines are resistant to Fas-induced apoptosis and highly sensitive to TRAIL-induced apoptosis. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 6. issue 10. 2001-03-22. PMID:11051265. |
seven pediatric rhabdomyosarcoma (rms) cell lines were resistant to the induction of apoptosis via the fas death receptor. |
2001-03-22 |
2023-08-12 |
Not clear |
| F Rodier, R Bertrand, M Bossolasco, A M Mes-Masso. Polyomavirus large T-antigen protects mouse cells from Fas-, TNF-alpha- and taxol-induced apoptosis. Oncogene. vol 19. issue 54. 2001-03-22. PMID:11175340. |
taken together, these results indicate that pylt-ag can be a potent inhibitor of fas(r)(ab)-, tnf-alpha- and taxol-induced apoptosis. |
2001-03-22 |
2023-08-12 |
mouse |
| W S Park, R R Oh, Y S Kim, J Y Park, S H Lee, M S Shin, S Y Kim, P J Kim, H K Lee, N Y Yoo, J Y Le. Somatic mutations in the death domain of the Fas (Apo-1/CD95) gene in gastric cancer. The Journal of pathology. vol 193. issue 2. 2001-03-22. PMID:11180161. |
the mutation of the primary structure of the fas gene might also be one of the possible mechanisms that disrupt fas-mediated apoptosis in tumour cells. |
2001-03-22 |
2023-08-12 |
Not clear |
| M Mogi, K Fukuo, J Yang, T Suhara, T Ogihar. Hypoxia stimulates release of the soluble form of fas ligand that inhibits endothelial cell apoptosis. Laboratory investigation; a journal of technical methods and pathology. vol 81. issue 2. 2001-03-22. PMID:11232639. |
hypoxia stimulates release of the soluble form of fas ligand that inhibits endothelial cell apoptosis. |
2001-03-22 |
2023-08-12 |
human |
| K H Choi, T I Kim, D L Chong, H Y Lee, D S Ha. Gentamicin induced apoptosis of renal tubular epithelial (LLC-PK1) cells. The Korean journal of internal medicine. vol 15. issue 3. 2001-03-22. PMID:11242810. |
however, the 15-day gm treatment did not cause a significant elevation in the expression of the 45 kd fas protein, the cell surface molecule that stimulates apoptosis, by western blot analysis. |
2001-03-22 |
2023-08-12 |
Not clear |
| R Mouawad, E C Antoine, D Khayat, C Soubran. Effect of endogenous interleukin-6 on Fas (APO-1/CD95) receptor expression in advanced melanoma patients. Cytokines, cellular & molecular therapy. vol 6. issue 3. 2001-03-15. PMID:11140882. |
in the present study, we investigated the relationship between endogenous il-6 and apoptosis signal through fas (apo-1/cd95) receptor expression in 9 responder and 15 refractory patients with metastatic disease treated by biochemotherapy. |
2001-03-15 |
2023-08-12 |
Not clear |
| R Mouawad, E C Antoine, D Khayat, C Soubran. Effect of endogenous interleukin-6 on Fas (APO-1/CD95) receptor expression in advanced melanoma patients. Cytokines, cellular & molecular therapy. vol 6. issue 3. 2001-03-15. PMID:11140882. |
these results suggest that the increased endogenous il-6 level in refractory patients may inhibit apoptosis via modulation of fas expression. |
2001-03-15 |
2023-08-12 |
Not clear |
| S Grimaudo, M V Raimondi, F Capone, A Chimirri, F Poretto, A M Monforte, D Simoni, M Tolome. Apoptotic effects of thiazolobenzimidazole derivatives on sensitive and multidrug resistant leukaemic cells. European journal of cancer (Oxford, England : 1990). vol 37. issue 1. 2001-03-15. PMID:11165139. |
on the contrary, the blocking of fl-associated cell surface antigen (fas) using a specific fas-blocking monoclonal antibody did not affect the level of apoptosis induced by tbz-4-och3 suggesting that the fas pathway was not involved. |
2001-03-15 |
2023-08-12 |
Not clear |
| C T Chou, J S Yang, M R Le. Apoptosis in rheumatoid arthritis--expression of Fas, Fas-L, p53, and Bcl-2 in rheumatoid synovial tissues. The Journal of pathology. vol 193. issue 1. 2001-03-15. PMID:11169523. |
apoptosis in rheumatoid arthritis--expression of fas, fas-l, p53, and bcl-2 in rheumatoid synovial tissues. |
2001-03-15 |
2023-08-12 |
Not clear |
| C T Chou, J S Yang, M R Le. Apoptosis in rheumatoid arthritis--expression of Fas, Fas-L, p53, and Bcl-2 in rheumatoid synovial tissues. The Journal of pathology. vol 193. issue 1. 2001-03-15. PMID:11169523. |
these results indicate that apoptosis in ra is strongly associated with the expression of fas and p53, but not bcl-2. |
2001-03-15 |
2023-08-12 |
Not clear |
| R Mouawad, D Khayat, C Soubran. Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in advanced melanoma. Melanoma research. vol 10. issue 5. 2001-03-08. PMID:11095407. |
plasma fas ligand, an inducer of apoptosis, and plasma soluble fas, an inhibitor of apoptosis, in advanced melanoma. |
2001-03-08 |
2023-08-12 |
Not clear |
| R Mouawad, D Khayat, C Soubran. Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in advanced melanoma. Melanoma research. vol 10. issue 5. 2001-03-08. PMID:11095407. |
the transmembrane receptor fas/apo-1, together with its protein-binding partner (fas ligand), is a key regulator of programmed cell death and induces apoptosis when it binds fas ligand (fasl) or soluble fas ligand (sfasl). |
2001-03-08 |
2023-08-12 |
Not clear |
| R Mouawad, D Khayat, C Soubran. Plasma Fas ligand, an inducer of apoptosis, and plasma soluble Fas, an inhibitor of apoptosis, in advanced melanoma. Melanoma research. vol 10. issue 5. 2001-03-08. PMID:11095407. |
however, soluble fas (sfas) blocks apoptosis by inhibiting binding between fas and fasl or sfasl. |
2001-03-08 |
2023-08-12 |
Not clear |
| G S Filippatos, K Tsilias, K Venetsanou, E Karambinos, D Manolatos, A Kranidis, J Antonellis, F Kardaras, L Anthopoulos, G Baltopoulo. Leptin serum levels in cachectic heart failure patients. Relationship with tumor necrosis factor-alpha system. International journal of cardiology. vol 76. issue 2-3. 2001-03-08. PMID:11104865. |
to investigate the role of leptin and regulators of apoptosis in cardiac cachexia we compared leptin concentrations and their relation to the tnf system, interleukin 1-beta (il-1b), and soluble fas in patients with heart failure with and without cachexia. |
2001-03-08 |
2023-08-12 |
Not clear |
| J M Wigginton, J W Park, M E Gruys, H A Young, C L Jorcyk, T C Back, M J Brunda, R M Strieter, J Ward, J E Green, R H Wiltrou. Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 166. issue 2. 2001-03-08. PMID:11145697. |
in juvenile mice, early administration of il-12/pulse il-2 markedly limits the expected genetically programmed neoplastic transition within the mammary epithelium and does so in conjunction with enhancement of constitutive fas and pronounced induction of local fas ligand gene expression, t cell infiltration, and induction of apoptosis within the mammary epithelium. |
2001-03-08 |
2023-08-12 |
mouse |
| D A Jabs, B Lee, J Whittum-Hudson, R A Prendergas. The role of Fas-Fas ligand-mediated apoptosis in autoimmune lacrimal gland disease in MRL/MpJ mice. Investigative ophthalmology & visual science. vol 42. issue 2. 2001-03-08. PMID:11157873. |
this mutation results in defective fas protein, defective lymphocytic apoptosis, and accelerated autoimmune lacrimal gland disease in mrl/lpr mice. |
2001-03-08 |
2023-08-12 |
mouse |
| K L Serrao, J D Fortenberry, M L Owens, F L Harris, L A Brow. Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand. American journal of physiology. Lung cellular and molecular physiology. vol 280. issue 2. 2001-03-08. PMID:11159009. |
neutrophils induce apoptosis of lung epithelial cells via release of soluble fas ligand. |
2001-03-08 |
2023-08-12 |
human |
| K L Serrao, J D Fortenberry, M L Owens, F L Harris, L A Brow. Neutrophils induce apoptosis of lung epithelial cells via release of soluble Fas ligand. American journal of physiology. Lung cellular and molecular physiology. vol 280. issue 2. 2001-03-08. PMID:11159009. |
neutrophils release soluble fas ligand (sfasl), which can induce apoptosis in certain fas-bearing cell types (liles wc, kiener pa, ledbetter ja, aruffo a, and klebanoff sj. |
2001-03-08 |
2023-08-12 |
human |