| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philipp M Lenzlinger, Andreas Marx, Otmar Trentz, Thomas Kossmann, Maria Cristina Morganti-Kossman. Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans. Journal of neuroimmunology. vol 122. issue 1-2. 2002-02-21. PMID:11777556. |
maximal csf levels of sfas correlated significantly (r(2)=0.8191, p<0.001) with the early peaks of neuron-specific enolase in csf (a marker for neuronal cell destruction), indicating that activation of the fas mediated pathway of apoptosis may be in part the direct result of the initial trauma. |
2002-02-21 |
2023-08-12 |
Not clear |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
fas ligand-expressing b-1a lymphocytes mediate cd4(+)-t-cell apoptosis during schistosomal infection: induction by interleukin 4 (il-4) and il-10. |
2002-02-21 |
2023-08-12 |
mouse |
| Steven K Lundy, Dov L Boro. Fas ligand-expressing B-1a lymphocytes mediate CD4(+)-T-cell apoptosis during schistosomal infection: induction by interleukin 4 (IL-4) and IL-10. Infection and immunity. vol 70. issue 2. 2002-02-21. PMID:11796615. |
a previous study of the murine model of schistosoma mansoni infection has implicated splenic cd19(+) b lymphocytes as fas ligand (fasl)-bearing mediators of cd4(+) t-lymphocyte apoptosis. |
2002-02-21 |
2023-08-12 |
mouse |
| Hartmut Jaeschke, Gregory J Gores, Arthur I Cederbaum, Jack A Hinson, Dominique Pessayre, John J Lemaster. Mechanisms of hepatotoxicity. Toxicological sciences : an official journal of the Society of Toxicology. vol 65. issue 2. 2002-02-21. PMID:11812920. |
in cholestatic disease, endogenously generated bile acids produce hepatocellular apoptosis by stimulating fas translocation from the cytoplasm to the plasma membrane where self-aggregation occurs to trigger apoptosis. |
2002-02-21 |
2023-08-12 |
mouse |
| Kenji Takahashi, Osamu Inanami, Masanobu Hayashi, Mikinori Kuwabar. Protein synthesis-dependent apoptotic signalling pathway in X-irradiated MOLT-4 human leukaemia cell line. International journal of radiation biology. vol 78. issue 2. 2002-02-19. PMID:11779361. |
to demonstrate whether protein synthesis is required for ionizing radiation-induced apoptosis through activation of caspases in human leukaemia cell line molt-4, the effects of a protein synthesis inhibitor, cycloheximide, on the apoptotic signalling pathway including the activation of caspase family and stress-activated protein kinase/c-jun n-terminal kinase (sapk/jnk), and the expression of fas/cd95/apo-1 (fas) were examined in x-irradiated molt-4 cells. |
2002-02-19 |
2023-08-12 |
human |
| M Krzyzowska, F Sabri, A De Milito, C Missailidis, A Schollenberger, M G Niemialtowski, F Chiod. Cross-linking of LFA-1 molecule enhances Fas mediated apoptosis of Jurkat and Burkitt lymphoma cell lines. Cell death and differentiation. vol 8. issue 11. 2002-02-15. PMID:11687890. |
cross-linking of lfa-1 molecule enhances fas mediated apoptosis of jurkat and burkitt lymphoma cell lines. |
2002-02-15 |
2023-08-12 |
Not clear |
| Bin Zhang, George C Prendergast, Robert G Fento. Farnesyltransferase inhibitors reverse Ras-mediated inhibition of Fas gene expression. Cancer research. vol 62. issue 2. 2002-02-15. PMID:11809695. |
this is manifested by an increase in fas mrna, fas cell surface expression, and fas-induced apoptosis. |
2002-02-15 |
2023-08-12 |
Not clear |
| O Fromigué, N Kheddoumi, A Lomri, P J Marie, J J Bod. Breast cancer cells release factors that induced apoptosis in human bone marrow stromal cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 16. issue 9. 2002-02-14. PMID:11547830. |
deprivation of mcf-7 cm from active fasligand by saturation with a soluble fas molecule suppressed the induction of fhso-6 apoptosis, whereas fibroblast cm, which did not contain fasligand, only weakly modified fhso-6 cell survival because of increased cell necrosis. |
2002-02-14 |
2023-08-12 |
human |
| N Mitsiades, V Poulaki, C S Mitsiades, K C Anderso. Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug. Expert opinion on investigational drugs. vol 10. issue 6. 2002-02-14. PMID:11772236. |
in particular, synthetic mmpis may directly induce apoptosis of cancer cells via their inhibitory effect on the shedding of fas ligand (fasl), a transmembrane member of the tnf superfamily that kills susceptible cells through its receptor, fas. |
2002-02-14 |
2023-08-12 |
human |
| Olivier Terradillos, Alix de La Coste, Teresa Pollicino, Christine Neuveut, Delphine Sitterlin, Hervé Lecoeur, Marie-Lise Gougeon, Axel Kahn, Marie-Annick Buendi. The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver. Oncogene. vol 21. issue 3. 2002-02-14. PMID:11821950. |
the hepatitis b virus x protein abrogates bcl-2-mediated protection against fas apoptosis in the liver. |
2002-02-14 |
2023-08-12 |
mouse |
| Olivier Terradillos, Alix de La Coste, Teresa Pollicino, Christine Neuveut, Delphine Sitterlin, Hervé Lecoeur, Marie-Lise Gougeon, Axel Kahn, Marie-Annick Buendi. The hepatitis B virus X protein abrogates Bcl-2-mediated protection against Fas apoptosis in the liver. Oncogene. vol 21. issue 3. 2002-02-14. PMID:11821950. |
in a lethal challenge with fas antibodies, hbx expressed at low levels restored sensitivity to fas-mediated apoptosis and fulminant hepatic failure in mice overexpressing bcl-2. |
2002-02-14 |
2023-08-12 |
mouse |
| C Y Ho, C K Wong, E K Li, W K La. Effects of dexamethasone on the expression of Fas molecules and apoptosis of lymphocytes in patients with systemic lupus erythematosus. Immunological investigations. vol 30. issue 3. 2002-02-13. PMID:11570643. |
effects of dexamethasone on the expression of fas molecules and apoptosis of lymphocytes in patients with systemic lupus erythematosus. |
2002-02-13 |
2023-08-12 |
human |
| C Y Ho, C K Wong, E K Li, W K La. Effects of dexamethasone on the expression of Fas molecules and apoptosis of lymphocytes in patients with systemic lupus erythematosus. Immunological investigations. vol 30. issue 3. 2002-02-13. PMID:11570643. |
we examined dexamethasone (dex)-induced apoptosis and fas expression in peripheral blood lymphocytes of sle patients and normal subjects. |
2002-02-13 |
2023-08-12 |
human |
| C Y Ho, C K Wong, E K Li, W K La. Effects of dexamethasone on the expression of Fas molecules and apoptosis of lymphocytes in patients with systemic lupus erythematosus. Immunological investigations. vol 30. issue 3. 2002-02-13. PMID:11570643. |
percentages of apoptosis and expression of fas molecule in lymphocytes were assessed by flow cytometry. |
2002-02-13 |
2023-08-12 |
human |
| L Boldrini, P Faviana, S Gisfredi, D Di Quirico, M Lucchi, A Mussi, C A Angeletti, F Baldinotti, A Fogli, P Simi, F Basolo, F Pingitore, G Fontanin. Identification of Fas (APO-1/CD95) and p53 gene mutations in non-small cell lung cancer. International journal of oncology. vol 20. issue 1. 2002-02-13. PMID:11743657. |
one of the possible mechanisms for resistance to apoptosis signaling in the immune system as well as in the pathogenesis of non-lymphoid malignancies is the presence of fas mutations within the entire gene. |
2002-02-13 |
2023-08-12 |
Not clear |
| L Cheng, Y Che. Anti-Fas antibody induces apoptosis in cultured human renal interstitial fibroblasts. Chinese medical journal. vol 114. issue 2. 2002-02-13. PMID:11780198. |
to detect if fas is expressed in human renal interstitial fibroblasts (hrifs) and apoptosis of hrifs can be induced by specific anti-fas antibody. |
2002-02-13 |
2023-08-12 |
human |
| Marco Cippitelli, Cinzia Fionda, Danilo Di Bona, Francesca Di Rosa, Aldo Lupo, Mario Piccoli, Luigi Frati, Angela Santon. Negative regulation of CD95 ligand gene expression by vitamin D3 in T lymphocytes. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 3. 2002-02-12. PMID:11801650. |
fas (apo-1/cd95) and its ligand (fasl/cd95l) are cell surface proteins whose interaction activates apoptosis of fas-expressing targets. |
2002-02-12 |
2023-08-12 |
Not clear |
| Hans J J van der Vliet, B Mary E von Blomberg, Mette D Hazenberg, Nobusuke Nishi, Sigrid A Otto, Birgit H van Benthem, Maria Prins, Frans A Claessen, Alfons J M van den Eertwegh, Giuseppe Giaccone, Frank Miedema, Rik J Scheper, Herbert M Pined. Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 3. 2002-02-12. PMID:11801694. |
because a small minority of valpha24+vbeta11+ nkt cells of healthy donors expressed hiv-1 (co)receptors and the vast majority of valpha24+vbeta11+ nkt cells in hiv-1-infected individuals expressed the fas receptor, the depletion was more likely due to fas-mediated apoptosis than to preferential infection of valpha24+vbeta11+ nkt cells by hiv-1. |
2002-02-12 |
2023-08-12 |
human |
| Christine Odoux, Andreas Albers, Andrew A Amoscato, Michael T Lotze, Michael K K Won. TRAIL, FasL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer. International journal of cancer. vol 97. issue 4. 2002-02-12. PMID:11802207. |
fas and trail receptors (dr4 and dr5) are tnf family members and act as death signal transduction proteins in the apoptosis cascade. |
2002-02-12 |
2023-08-12 |
human |
| Christine Odoux, Andreas Albers, Andrew A Amoscato, Michael T Lotze, Michael K K Won. TRAIL, FasL and a blocking anti-DR5 antibody augment paclitaxel-induced apoptosis in human non-small-cell lung cancer. International journal of cancer. vol 97. issue 4. 2002-02-12. PMID:11802207. |
despite the importance of pa in lung cancer treatment, the function of fas, dr4 and dr5 in pa-induced apoptosis, as well as the effect of their respective ligands fasl and trail alone or in combination with pa, remains poorly understood. |
2002-02-12 |
2023-08-12 |
human |