| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Koko Katagiri, Masakazu Hattori, Nagahiro Minato, Tatsuo Kinash. Rap1 functions as a key regulator of T-cell and antigen-presenting cell interactions and modulates T-cell responses. Molecular and cellular biology. vol 22. issue 4. 2002-03-01. PMID:11809793. |
conversely, augmented antigen-dependent rap1 activation by the expression of wild-type rap1 enhances these responses but culminates in apoptosis by fas and fasl. |
2002-03-01 |
2023-08-12 |
Not clear |
| Leiming Li, Masaya Okura, Akira Imamot. Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion. Molecular and cellular biology. vol 22. issue 4. 2002-03-01. PMID:11809811. |
it is therefore likely that the primary cause of cell rounding and detachment induced by fa-csk involves dysfunction of fas rather than caspase-mediated apoptosis that may result from possible loss of survival signals mediated by src family kinases. |
2002-03-01 |
2023-08-12 |
Not clear |
| Xue Wei Meng, Michael P Heldebrant, Scott H Kaufman. Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain. The Journal of biological chemistry. vol 277. issue 5. 2002-02-28. PMID:11729181. |
previous studies have demonstrated that phorbol 12-myristate 13-acetate (pma), a protein kinase c activator, inhibits fas (cd95)-mediated apoptosis in jurkat (type ii) cells but not skw6.4 (type i) cells. |
2002-02-28 |
2023-08-12 |
Not clear |
| Xue Wei Meng, Michael P Heldebrant, Scott H Kaufman. Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain. The Journal of biological chemistry. vol 277. issue 5. 2002-02-28. PMID:11729181. |
although the protein kinase inhibitor bisindoylmaleimide viii increased apoptosis induced by agonistic anti-fas antibody, tumor necrosis factor-alpha, and trail, these effects were not observed with the protein kinase c inhibitor h7 and were not associated with increased fadd recruitment to fas. |
2002-02-28 |
2023-08-12 |
Not clear |
| Sung-Chul Li. Expression of Fas ligand and sFas ligand in human gastric adenocarcinomas. Oncology reports. vol 9. issue 1. 2002-02-28. PMID:11748465. |
this finding suggested fas-mediated apoptosis in response to fas-l expression by gastric adenocarcinoma, providing evidence to support a fas counterattack and indicated that the serum sfas-l level is a useful indicator in evaluating preoperative diagnosis and postoperative follow-up of gastric adenocarcinoma. |
2002-02-28 |
2023-08-12 |
human |
| K Masuko-Hongo, M Sakata, G H Yuan, H Onuma, H Nakamura, H Aoki, T Kato, K Nishiok. Expression of Fas-associated death domain-like interleukin-1beta-converting enzyme (FLICE) inhibitory protein (FLIP) in human articular chondrocytes: possible contribution to the resistance to Fas-mediated death of in vitro cultured human articular chondrocytes. Rheumatology international. vol 21. issue 3. 2002-02-28. PMID:11765224. |
to investigate whether fas-mediated apoptosis has a role in this process, the presence of fas mrna and expression of cell surface fas protein in monolayer-cultured human articular chondrocytes was analyzed. |
2002-02-28 |
2023-08-12 |
human |
| D J Granville, H Jiang, B M McManus, D W Hun. Fas ligand and TRAIL augment the effect of photodynamic therapy on the induction of apoptosis in JURKAT cells. International immunopharmacology. vol 1. issue 9-10. 2002-02-26. PMID:11562074. |
fas ligand and trail augment the effect of photodynamic therapy on the induction of apoptosis in jurkat cells. |
2002-02-26 |
2023-08-12 |
Not clear |
| D J Granville, H Jiang, B M McManus, D W Hun. Fas ligand and TRAIL augment the effect of photodynamic therapy on the induction of apoptosis in JURKAT cells. International immunopharmacology. vol 1. issue 9-10. 2002-02-26. PMID:11562074. |
tumor necrosis factor-related apoptosis inducing ligand (trail) and fas ligand (fasl) trigger apoptosis by stimulating the formation of a death inducing signaling complex at the cytoplasmic terminus of their respective receptors. |
2002-02-26 |
2023-08-12 |
Not clear |
| Pascal Meier, Eric Dayer, Edouard Blanc, Jean-Pierre Wauter. Early T cell activation correlates with expression of apoptosis markers in patients with end-stage renal disease. Journal of the American Society of Nephrology : JASN. vol 13. issue 1. 2002-02-25. PMID:11752039. |
to test this hypothesis, cd3+ t cell activation (cd69) and apoptosis (annexin v, cd95 (fas), and dna fragmentation) were analyzed in a case control study after blood draw sampling (ex vivo), in culture conditions, and after phytohemagglutinin or anti-cd3 stimulation. |
2002-02-25 |
2023-08-12 |
Not clear |
| Pascal Meier, Eric Dayer, Edouard Blanc, Jean-Pierre Wauter. Early T cell activation correlates with expression of apoptosis markers in patients with end-stage renal disease. Journal of the American Society of Nephrology : JASN. vol 13. issue 1. 2002-02-25. PMID:11752039. |
t cells from chronic hd patients and patients with esrf thus showed an aberrant state of early activation that contrasted with an increased proportion of annexin v and cd95 (fas)-positive t cells engaged in apoptosis, as confirmed by dna fragmentation. |
2002-02-25 |
2023-08-12 |
Not clear |
| Ilana Kronfeld, Gila Kazimirsky, Erwin W Gelfand, Chaya Brodi. NGF rescues human B lymphocytes from anti-IgM induced apoptosis by activation of PKCzeta. European journal of immunology. vol 32. issue 1. 2002-02-25. PMID:11754354. |
the low-affinity ngfr, p75, shares structural homology with the b cell antigen, cd40, tumor necrosis factor (tnf) receptor and fas antigen (apo-1), which play a role in cell apoptosis. |
2002-02-25 |
2023-08-12 |
human |
| Josef Bodor, Jana Bodorova, Catherine Bare, Deborah L Hodge, Howard A Young, Ronald E Gres. Differential inducibility of the transcriptional repressor ICER and its role in modulation of Fas ligand expression in T and NK lymphocytes. European journal of immunology. vol 32. issue 1. 2002-02-25. PMID:11754361. |
the engagement of antigen receptor can initiate apoptosis of t lymphocytes through the induced expression of fas ligand (fasl). |
2002-02-25 |
2023-08-12 |
human |
| Masashige Bando, Yasunobu Miyake, Masashi Shiina, Masaaki Wachi, Kazuo Nagai, Takao Kataok. Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells. Biochemical and biophysical research communications. vol 290. issue 1. 2002-02-25. PMID:11779164. |
actin cytoskeleton is required for early apoptosis signaling induced by anti-fas antibody but not fas ligand in murine b lymphoma a20 cells. |
2002-02-25 |
2023-08-12 |
Not clear |
| P Augstein, A Dunger, C Salzsieder, P Heinke, R Kubernath, J Bahr, U Fischer, R Rettig, E Salzsiede. Cell surface trafficking of Fas in NIT-1 cells and dissection of surface and total Fas expression. Biochemical and biophysical research communications. vol 290. issue 1. 2002-02-25. PMID:11779190. |
the appearance of fas receptor at the surface of pancreatic beta-cells affected by progressive insulitis strongly suggests that fas-mediated beta-cell apoptosis plays an important role in the pathogenesis of type 1 diabetes. |
2002-02-25 |
2023-08-12 |
mouse |
| L F Lincz, T X Yeh, A Spence. TRAIL-induced eradication of primary tumour cells from multiple myeloma patient bone marrows is not related to TRAIL receptor expression or prior chemotherapy. Leukemia. vol 15. issue 10. 2002-02-22. PMID:11587225. |
tnf-related apoptosis-inducing ligand (trail) shares significant homology with cd95 (fas) ligand and has the ability to induce apoptosis in sensitive cells through a caspase-mediated pathway. |
2002-02-22 |
2023-08-12 |
human |
| T Maeda, S Kamihir. Apoptosis, Part II: The role of mutated Fas genes in tumorigenesis. Advances in clinical chemistry. vol 36. 2002-02-22. PMID:11605256. |
apoptosis, part ii: the role of mutated fas genes in tumorigenesis. |
2002-02-22 |
2023-08-12 |
Not clear |
| Alexander R Moise, Jason R Grant, Timothy Z Vitalis, Wilfred A Jefferie. Adenovirus E3-6.7K maintains calcium homeostasis and prevents apoptosis and arachidonic acid release. Journal of virology. vol 76. issue 4. 2002-02-22. PMID:11799152. |
in addition, e3-6.7k protected cells against apoptosis induced through fas, tnf receptor, and trail receptors. |
2002-02-22 |
2023-08-12 |
human |
| Y Kanda, C Ara, A Chizuka, R Yamamoto, T Hamaki, M Suguro, T Matsuyama, N Takezako, A Miwa, J Tohma, K Shirakawa, T Yatomi, N Nakamura, H Hirai, A Togaw. Lack of correlation between clinical characteristics and serum soluble Fas ligand levels in patients with multiple myeloma. Leukemia & lymphoma. vol 40. issue 3-4. 2002-02-21. PMID:11426557. |
showed that the neoplastic plasma cells express fas ligand (fasl), which transmits a signal of apoptosis upon ligation to fas, and suggested that the fasl suppresses the t-cells activated against malignant cells, resulting in escape from tumour immunity. |
2002-02-21 |
2023-08-12 |
Not clear |
| H Ungefroren, M L Kruse, A Trauzold, S Roeschmann, C Roeder, A Arlt, D Henne-Bruns, H Kalthof. FAP-1 in pancreatic cancer cells: functional and mechanistic studies on its inhibitory role in CD95-mediated apoptosis. Journal of cell science. vol 114. issue Pt 15. 2002-02-21. PMID:11683408. |
in this study we investigated the functional role of fap-1 as a potential inhibitor of cd95 (fas, apo-1)-mediated apoptosis in pancreatic cancer cells. |
2002-02-21 |
2023-08-12 |
Not clear |
| Philipp M Lenzlinger, Andreas Marx, Otmar Trentz, Thomas Kossmann, Maria Cristina Morganti-Kossman. Prolonged intrathecal release of soluble Fas following severe traumatic brain injury in humans. Journal of neuroimmunology. vol 122. issue 1-2. 2002-02-21. PMID:11777556. |
a truncated form of the fas receptor, soluble fas (sfas) may indicate activation of the fas/fasl system and act as a negative feedback mechanism, thereby inhibiting fas mediated apoptosis. |
2002-02-21 |
2023-08-12 |
Not clear |