| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James A Mahoney, Joseph A Odin, Sarah M White, David Shaffer, Andrew Koff, Livia Casciola-Rosen, Antony Rose. The human homologue of the yeast polyubiquitination factor Ufd2p is cleaved by caspase 6 and granzyme B during apoptosis. The Biochemical journal. vol 361. issue Pt 3. 2002-03-12. PMID:11802788. |
in the present study, we demonstrate that a human homologue of ufd2p (a yeast protein that catalyses the formation of long polyubiquitin chains, and is implicated in responses to environmental stress), ufd2 (ubiquitin fusion degradation protein-2), is cleaved during apoptosis induced by multiple stimuli, including uvb irradiation, fas ligation, staurosporine treatment and cytotoxic lymphocyte granule-induced death. |
2002-03-12 |
2023-08-12 |
mouse |
| F M Ruemmele, J F Beaulieu, J O'Connell, M W Bennett, E G Seidman, M J Lentz. The susceptibility to Fas-induced apoptosis in normal enterocytes is regulated on the level of cIAP1 and 2. Biochemical and biophysical research communications. vol 290. issue 4. 2002-03-12. PMID:11812006. |
however, no apoptosis occurred after activation of fas, whereas an upregulation of antiapoptotic ciap1 and 2 was observed. |
2002-03-12 |
2023-08-12 |
human |
| John H Stewart, Dao M Nguyen, G Aaron Chen, David S Schrum. Induction of apoptosis in malignant pleural mesothelioma cells by activation of the Fas (Apo-1/CD95) death-signal pathway. The Journal of thoracic and cardiovascular surgery. vol 123. issue 2. 2002-03-12. PMID:11828289. |
induction of apoptosis in malignant pleural mesothelioma cells by activation of the fas (apo-1/cd95) death-signal pathway. |
2002-03-12 |
2023-08-12 |
Not clear |
| F Koga, K Arai, T Kamai, H Abe, K Yoshid. Fas labeling status does not correlate with apoptosis of renal cell carcinoma in vivo. Anticancer research. vol 21. issue 5. 2002-03-12. PMID:11848472. |
fas labeling status does not correlate with apoptosis of renal cell carcinoma in vivo. |
2002-03-12 |
2023-08-12 |
Not clear |
| F Koga, K Arai, T Kamai, H Abe, K Yoshid. Fas labeling status does not correlate with apoptosis of renal cell carcinoma in vivo. Anticancer research. vol 21. issue 5. 2002-03-12. PMID:11848472. |
contribution of the fas system to apoptosis of renal cell carcinoma (rcc) was investigated in vivo. |
2002-03-12 |
2023-08-12 |
Not clear |
| N Shinoura, T Furitsu, A Asai, T Kirino, H Hamad. Co-transduction of p27Kip1 strongly augments Fas ligand- and caspase-8-mediated apoptosis in U-373MG glioma cells. Anticancer research. vol 21. issue 5. 2002-03-12. PMID:11848481. |
co-transduction of p27kip1 strongly augments fas ligand- and caspase-8-mediated apoptosis in u-373mg glioma cells. |
2002-03-12 |
2023-08-12 |
Not clear |
| N Shinoura, T Furitsu, A Asai, T Kirino, H Hamad. Co-transduction of p27Kip1 strongly augments Fas ligand- and caspase-8-mediated apoptosis in U-373MG glioma cells. Anticancer research. vol 21. issue 5. 2002-03-12. PMID:11848481. |
as malignant gliomas express fas at high levels, the relationship between fas-mediated apoptosis and p27kip1 expression may improve therapeutic approaches for treating gliomas. |
2002-03-12 |
2023-08-12 |
Not clear |
| Tineke Timmer, Elisabeth G E de Vries, Steven de Jon. Fas receptor-mediated apoptosis: a clinical application? The Journal of pathology. vol 196. issue 2. 2002-03-11. PMID:11793363. |
fas receptor-mediated apoptosis: a clinical application? |
2002-03-11 |
2023-08-12 |
mouse |
| Tineke Timmer, Elisabeth G E de Vries, Steven de Jon. Fas receptor-mediated apoptosis: a clinical application? The Journal of pathology. vol 196. issue 2. 2002-03-11. PMID:11793363. |
cross-linking of fas by its ligand, fasl, or agonistic anti-fas antibodies, induces apoptosis of cells expressing fas on the membrane by triggering a cascade of caspases. |
2002-03-11 |
2023-08-12 |
mouse |
| Tineke Timmer, Elisabeth G E de Vries, Steven de Jon. Fas receptor-mediated apoptosis: a clinical application? The Journal of pathology. vol 196. issue 2. 2002-03-11. PMID:11793363. |
since many different tumours express fas on their membrane, targeting fas-mediated apoptosis by anti-fas antibodies may be a promising anticancer therapy. |
2002-03-11 |
2023-08-12 |
mouse |
| Tineke Timmer, Elisabeth G E de Vries, Steven de Jon. Fas receptor-mediated apoptosis: a clinical application? The Journal of pathology. vol 196. issue 2. 2002-03-11. PMID:11793363. |
in addition, mutations in the fas or p53 gene can also influence the sensitivity for fas-mediated apoptosis. |
2002-03-11 |
2023-08-12 |
mouse |
| R J Sokol, C Mac. Etiopathogenesis of biliary atresia. Seminars in liver disease. vol 21. issue 4. 2002-03-08. PMID:11745039. |
fas ligand upregulation and apoptosis of bile duct epithelia have been demonstrated in human specimens, as well as t-lymphocyte and macrophage activation in portal tracts. |
2002-03-08 |
2023-08-12 |
mouse |
| S Nakatsuka, T Takakuwa, K Aozas. [Hypermethylation of DAP-kinase gene CpG Island in malignant lymphoma with B-cell phenotype]. Rinsho byori. The Japanese journal of clinical pathology. vol 49. issue 12. 2002-03-08. PMID:11797395. |
death-associated protein-kinase(dap-kinase) is a pro-apoptotic serine/threonine kinase with a death domain, which is involved in apoptosis induced by interferon-gamma, tumor necrosis factor-alpha, and fas ligand. |
2002-03-08 |
2023-08-12 |
Not clear |
| I Sasagawa, H Yazawa, Y Suzuki, T Nakad. Stress and testicular germ cell apoptosis. Archives of andrology. vol 47. issue 3. 2002-03-07. PMID:11695845. |
the apoptosis of testicular germ cells would involve certain specific gene activities and proteins, including bcl-2 family, p53, and fas. |
2002-03-07 |
2023-08-12 |
rat |
| O Nishi, K Nishi, K Wada, Y Ohmoto, J Akur. Inhibition of lens epithelial cells by Fas-specific antibody activating Fas-Fas ligand system. Current eye research. vol 23. issue 3. 2002-03-07. PMID:11803481. |
to detect cell specific apoptosis factors, fas and fas ligand, and the common intracellular apoptosis modulators, interleukin-1 beta converting enzyme (ice)-like protease (caspase 1), bcl-2, bcl-xl and bax in lens epithelial cells (lec) of human cataracts. |
2002-03-07 |
2023-08-12 |
human |
| Ewa Filipowicz, P Adegboyega, R L Sanchez, Zoran Gatalic. Expression of CD95 (Fas) in sun-exposed human skin and cutaneous carcinomas. Cancer. vol 94. issue 3. 2002-03-07. PMID:11857317. |
apoptosis, triggered by the activation of cd95 (fas), is one of the most important defense mechanisms against uv light-induced carcinogenesis in experimental models, but the dynamics of cd95 expression in patients with sun-induced lesions are largely unknown. |
2002-03-07 |
2023-08-12 |
human |
| Cornel Badorff, Hartmut Ruetten, Sven Mueller, Meike Stahmer, Doris Gehring, Frank Jung, Christian Ihling, Andreas M Zeiher, Stefanie Dimmele. Fas receptor signaling inhibits glycogen synthase kinase 3 beta and induces cardiac hypertrophy following pressure overload. The Journal of clinical investigation. vol 109. issue 3. 2002-03-06. PMID:11827997. |
here, we identified fas receptor activation, a classical death signal causing apoptosis via activation of the caspase cascade in many cell types, as a novel pathway mediating cardiomyocyte hypertrophy in vitro and in vivo. |
2002-03-06 |
2023-08-12 |
mouse |
| Ganwei Lu, Bratislav M Janjic, Jelena Janjic, Theresa L Whiteside, Walter J Storkus, Nikola L Vujanovi. Innate direct anticancer effector function of human immature dendritic cells. II. Role of TNF, lymphotoxin-alpha(1)beta(2), Fas ligand, and TNF-related apoptosis-inducing ligand. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 4. 2002-03-04. PMID:11823516. |
we determine that human immature dcs express on their cell surface four different cytotoxic tnf family ligands: tnf, lymphotoxin-alpha(1)beta(2), fas ligand, and tnf-related apoptosis inducing ligand; while cancer cells express the corresponding death receptors. |
2002-03-04 |
2023-08-12 |
human |
| N Mitsiades, C S Mitsiades, V Poulaki, K C Anderson, S P Treo. Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma and other neoplasias. Expert opinion on investigational drugs. vol 10. issue 8. 2002-03-01. PMID:11772267. |
importantly, trail/apo2l-induced apoptosis was unaffected by il-6, a potent growth and survival factor for mm cells which, as we and others have previously shown, blocks various pro-apoptotic signals including fas ligand, which like trail/apo2l is also a member of the tnf family of ligands. |
2002-03-01 |
2023-08-12 |
mouse |
| K Lai, C Wang, X Gu. [The engulfment effects of macrophage on apoptotic eosinophils treated by anti-Fas monoclonal antibody in vitro]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 24. issue 3. 2002-03-01. PMID:11802955. |
expression of the fas antigen and induction of apoptosis in eosinophils (eos) by anti-fas antibody in vitro were investigated. |
2002-03-01 |
2023-08-12 |
Not clear |