| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Sugihara, N Yamada, T Tsujimura, T Iwasaki, K Yamashita, Y Takagi, M Tsuji, N Terad. Castration induces apoptosis in the male accessory sex organs of Fas-deficient lpr and Fas ligand-deficient gld mutant mice. In vivo (Athens, Greece). vol 15. issue 5. 2002-04-23. PMID:11695234. |
the present results suggest that the fas ligand-fas system plays little role in castration-induced apoptosis in the mouse male accessory sex organs such as the vp, sv, cg and ep. |
2002-04-23 |
2023-08-12 |
mouse |
| Mina Yaar, Sen Zhai, Richard E Fine, Patricia B Eisenhauer, Bennett L Arble, Kenneth B Stewart, Barbara A Gilchres. Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling. The Journal of biological chemistry. vol 277. issue 10. 2002-04-15. PMID:11756426. |
p75(ntr), a nerve growth factor co-receptor that has been implicated in apoptosis of neurons, is structurally related to fas and the receptors for tumor necrosis factor-alpha that display ligand independent assembly into trimers. |
2002-04-15 |
2023-08-12 |
rat |
| Joseph R Tumang, Robert S Negm, Laura A Solt, Thomas J Schneider, Thomas P Colarusso, William D Hastings, Robert T Woodland, Thomas L Rothstei. BCR engagement induces Fas resistance in primary B cells in the absence of functional Bruton's tyrosine kinase. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 6. 2002-04-15. PMID:11884437. |
the signaling mediator, bruton's tyrosine kinase (btk), is required for certain sig-triggered responses, and btk is reported to directly bind fas and block fas-mediated apoptosis. |
2002-04-15 |
2023-08-12 |
Not clear |
| Robert F Rich, William R Gree. Characterization of the Fas ligand/Fas-dependent apoptosis of antiretroviral, class I MHC tetramer-defined, CD8+ CTL by in vivo retrovirus-infected cells. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 6. 2002-04-15. PMID:11884442. |
characterization of the fas ligand/fas-dependent apoptosis of antiretroviral, class i mhc tetramer-defined, cd8+ ctl by in vivo retrovirus-infected cells. |
2002-04-15 |
2023-08-12 |
mouse |
| Robert F Rich, William R Gree. Characterization of the Fas ligand/Fas-dependent apoptosis of antiretroviral, class I MHC tetramer-defined, CD8+ CTL by in vivo retrovirus-infected cells. Journal of immunology (Baltimore, Md. : 1950). vol 168. issue 6. 2002-04-15. PMID:11884442. |
shortly thereafter, a high percentage of b6 tetramer(+) ctl cocultured with akr.h-2(b) veto cells was annexin v positive and fas(high), indicating apoptosis as the mechanism of veto cell inhibition. |
2002-04-15 |
2023-08-12 |
mouse |
| José E Cardier, Connie L Erickson-Mille. Fas (CD95)- and tumor necrosis factor-mediated apoptosis in liver endothelial cells: role of caspase-3 and the p38 MAPK. Microvascular research. vol 63. issue 1. 2002-04-12. PMID:11749068. |
fas (cd95)- and tumor necrosis factor-mediated apoptosis in liver endothelial cells: role of caspase-3 and the p38 mapk. |
2002-04-12 |
2023-08-12 |
Not clear |
| José E Cardier, Connie L Erickson-Mille. Fas (CD95)- and tumor necrosis factor-mediated apoptosis in liver endothelial cells: role of caspase-3 and the p38 MAPK. Microvascular research. vol 63. issue 1. 2002-04-12. PMID:11749068. |
recently, we showed that tnf enhances the susceptibility of endothelial cells from murine liver sinusoids (lec) to fas-mediated apoptosis, suggesting that signals transduced by fas and tnf receptors may synergistically increase intracellular death signals in these cells. |
2002-04-12 |
2023-08-12 |
Not clear |
| José E Cardier, Connie L Erickson-Mille. Fas (CD95)- and tumor necrosis factor-mediated apoptosis in liver endothelial cells: role of caspase-3 and the p38 MAPK. Microvascular research. vol 63. issue 1. 2002-04-12. PMID:11749068. |
in this work we evaluated whether caspase-3 and p38 are involved in lec apoptosis induced by fas and tnf. |
2002-04-12 |
2023-08-12 |
Not clear |
| Shuang Wei, Florentina Marches, Jozef Borvak, Weiping Zou, Jacqueline Channon, Michael White, Jay Radke, Marie-France Cesbron-Delauw, Tyler J Curie. Toxoplasma gondii-infected human myeloid dendritic cells induce T-lymphocyte dysfunction and contact-dependent apoptosis. Infection and immunity. vol 70. issue 4. 2002-04-11. PMID:11895936. |
t lymphocytes exposed to infected mddcs are significantly impaired in upregulation of cd69 and cd28, are refractory to activation, and die through contact-dependent apoptosis mediated by an as-yet-unidentified mechanism not requiring fas, tumor necrosis factor-related apoptosis-inducing ligand, leukocyte function antigen 1, intercellular adhesion molecule 1, tumor necrosis factor alpha, interleukin 10, alpha interferon, gamma interferon, prostaglandins, or reactive nitrogen intermediates. |
2002-04-11 |
2023-08-12 |
human |
| T Mustafa, T G Bjune, R Jonsson, R H Pando, R Nilse. Increased expression of fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection. Scandinavian journal of immunology. vol 54. issue 6. 2002-04-11. PMID:11902340. |
to study the location and mechanism of apoptosis within the human tuberculosis (tb) and leprosy lesions, parallel sections were analyzed for mycobacterial antigens (m.ag), fas ligand (fasl), fas, cd68 and mac387 by immunohistochemistry, and apoptotic cells by the terminal deoxynucleotidyl-transferase-mediated dutp-digoxigenin nick end labelling method. |
2002-04-11 |
2023-08-12 |
human |
| M Thome, J Tschop. Regulation of lymphocyte proliferation and death by FLIP. Nature reviews. Immunology. vol 1. issue 1. 2002-04-11. PMID:11905814. |
signals from members of the tumour-necrosis-factor receptor (tnf-r) family, such as fas and tnf-r1, activate the caspase cascade and result in lymphocyte death by apoptosis. |
2002-04-11 |
2023-08-12 |
Not clear |
| T Maruo, N Ishihara, T Samoto, H Murakoshi, J B Laoag-Fernandez, H Matsu. Regulation of human trophoblast proliferation and apoptosis during pregnancy. Early pregnancy (Online). vol 5. issue 1. 2002-04-09. PMID:11753500. |
pcna, bcl-2 protein and fas antigen expression were examined by the avidin/biotin immunoperoxidase method, while apoptosis was assessed by in situ dna 3'-end labeling method. |
2002-04-09 |
2023-08-12 |
human |
| C Schnurr, U Glatzel, R Tolba, A Hirner, T Mino. Fas receptor is upregulated in livers from non-heart-beating donors. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 33. issue 5-6. 2002-04-09. PMID:11805392. |
we suggested that apoptosis in nhbd livers might be mediated by the fas receptor. |
2002-04-09 |
2023-08-12 |
rat |
| C Schnurr, U Glatzel, R Tolba, A Hirner, T Mino. Fas receptor is upregulated in livers from non-heart-beating donors. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 33. issue 5-6. 2002-04-09. PMID:11805392. |
therefore the aim of our study was the detection and quantification of the fas receptor, fas mrna and apoptosis in nhbd livers. |
2002-04-09 |
2023-08-12 |
rat |
| C Schnurr, U Glatzel, R Tolba, A Hirner, T Mino. Fas receptor is upregulated in livers from non-heart-beating donors. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 33. issue 5-6. 2002-04-09. PMID:11805392. |
we conclude that upregulation of the fas receptor on hepatocytes in nhbds will prime these cells to eventually undergo apoptosis upon reperfusion in vivo. |
2002-04-09 |
2023-08-12 |
rat |
| C Schnurr, U Glatzel, R Tolba, A Hirner, T Mino. Fas receptor is upregulated in livers from non-heart-beating donors. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 33. issue 5-6. 2002-04-09. PMID:11805392. |
therefore, therapeutic modulation of the fas pathway must be considered as a new strategy in order to additionally protect nhbd livers which are otherwise prone to parenchymal apoptosis. |
2002-04-09 |
2023-08-12 |
rat |
| Mi-Ock Lee, Hyo-Jin Kang, Young Mi Kim, Ji-Hyun Oum, Jungchan Par. Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T-cells. European journal of biochemistry. vol 269. issue 4. 2002-04-05. PMID:11856352. |
retinoids are potent immune modulators that inhibit fas ligand (fasl) expression and thereby repress the activation-induced apoptosis of immature thymocytes and t-cell hybridomas. |
2002-04-05 |
2023-08-12 |
Not clear |
| Xue Wang, Marie C DeFrances, Yu Dai, Peter Pediaditakis, Carla Johnson, Aaron Bell, George K Michalopoulos, Reza Zarnega. A mechanism of cell survival: sequestration of Fas by the HGF receptor Met. Molecular cell. vol 9. issue 2. 2002-04-05. PMID:11864613. |
this interaction prevents fas self-aggregation and fas ligand binding, thus inhibiting fas activation and apoptosis. |
2002-04-05 |
2023-08-12 |
Not clear |
| Gary K Smith, David G Barrett, Kevin Blackburn, Michael Cory, Walter S Dallas, Roderick Davis, Daniel Hassler, Randy McConnell, Mary Moyer, Kurt Weave. Expression, preparation, and high-throughput screening of caspase-8: discovery of redox-based and steroid diacid inhibition. Archives of biochemistry and biophysics. vol 399. issue 2. 2002-04-05. PMID:11888206. |
because of the intimate role of caspase-8 in apoptosis signaling pathways from fas, tnfr1, and other death receptors, the enzyme is a potentially important therapeutic target. |
2002-04-05 |
2023-08-12 |
Not clear |
| Jianguo Ma, Karin A Reed, James M Gall. Cells designed to deliver anticancer drugs by apoptosis. Cancer research. vol 62. issue 5. 2002-04-05. PMID:11888909. |
significant apoptosis of flk-1:fas expression cells was observed in tumor, apparently driven by vegf secreted from tumor cells. |
2002-04-05 |
2023-08-12 |
mouse |