| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Janet Liversidge, Andrew Dick, Sharon Gordo. Nitric oxide mediates apoptosis through formation of peroxynitrite and Fas/Fas-ligand interactions in experimental autoimmune uveitis. The American journal of pathology. vol 160. issue 3. 2002-04-02. PMID:11891189. |
in this study we show that tissue damage within the eye during experimental autoimmune uveoretinitis correlates with peroxynitrite formation in infiltrating monocytes/macrophages within the outer retina together with extensive photoreceptor apoptosis and apoptosis of fas(+) t cells within the retina. |
2002-04-02 |
2023-08-12 |
Not clear |
| Wilfried Roth, Frank Stenner-Liewen, Krzysztof Pawlowski, Adam Godzik, John C Ree. Identification and characterization of DEDD2, a death effector domain-containing protein. The Journal of biological chemistry. vol 277. issue 9. 2002-04-01. PMID:11741985. |
overexpression of dedd2 induces moderate apoptosis and results in substantial sensitization to apoptosis induced by fas (cd95/apo-1), tumor necrosis factor-related apoptosis-inducing ligand (trail, apo2l), or fadd. |
2002-04-01 |
2023-08-12 |
human |
| X Prévill, E Sick, S Beauchard, M Ossevoort, J Tiollier, J P Revillard, M Jonke. 6-Methylprednisolone does not impair anti-thymocyte globulin (ATG) immunosuppressive activity in non-human primates. Transplant immunology. vol 9. issue 1. 2002-03-29. PMID:11680573. |
since atg can trigger fas (cd95) mediated t cell apoptosis, a process antagonized in vitro by corticosteroids, an important issue is whether corticosteroids could interfere with t cell depleting and immunosuppressive activities of atg. |
2002-03-29 |
2023-08-12 |
Not clear |
| N Shinoura, S Sakurai, F Shibasaki, A Asai, T Kirino, H Hamad. Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas. British journal of cancer. vol 86. issue 4. 2002-03-29. PMID:11870542. |
u251 cells transduced with fas concomitant with the apaf-1 and caspase-9 genes underwent drastic apoptosis. |
2002-03-29 |
2023-08-12 |
Not clear |
| Vladimir V Didenko, Hop N Ngo, Candace Minchew, David S Baski. Apoptosis of T lymphocytes invading glioblastomas multiforme: a possible tumor defense mechanism. Journal of neurosurgery. vol 96. issue 3. 2002-03-29. PMID:11883844. |
the goal of this study was to investigate whether apoptosis occurs in t lymphocytes that invade fas ligand (fasl)-expressing glioblastomas multiforme (gbms) and if its induction could be mediated by fas. |
2002-03-29 |
2023-08-12 |
Not clear |
| S Pianko, S Patella, G Ostapowicz, P Desmond, W Siever. Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection. Journal of viral hepatitis. vol 8. issue 6. 2002-03-27. PMID:11703571. |
the aims of this study were to evaluate the relationship between alcohol consumption and hepatocyte apoptosis in hcv-infected patients and to determine the role of fas in hcv-mediated apoptosis. |
2002-03-27 |
2023-08-12 |
human |
| S Pianko, S Patella, G Ostapowicz, P Desmond, W Siever. Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection. Journal of viral hepatitis. vol 8. issue 6. 2002-03-27. PMID:11703571. |
liver tissue from 44 hcv-infected patients with variable alcohol consumption, and 10 normal control subjects who did not consume alcohol was examined for hepatocyte apoptosis, proliferation and fas expression. |
2002-03-27 |
2023-08-12 |
human |
| S Pianko, S Patella, G Ostapowicz, P Desmond, W Siever. Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection. Journal of viral hepatitis. vol 8. issue 6. 2002-03-27. PMID:11703571. |
the degree of fas expression correlated with hepatocyte apoptosis as detected by terminal utp nick end labelling (tunel). |
2002-03-27 |
2023-08-12 |
human |
| S Pianko, S Patella, G Ostapowicz, P Desmond, W Siever. Fas-mediated hepatocyte apoptosis is increased by hepatitis C virus infection and alcohol consumption, and may be associated with hepatic fibrosis: mechanisms of liver cell injury in chronic hepatitis C virus infection. Journal of viral hepatitis. vol 8. issue 6. 2002-03-27. PMID:11703571. |
the correlation between fas expression and tunel supports the hypothesis that the fas-fas ligand interaction is the major mechanism for hcv-induced hepatocyte apoptosis. |
2002-03-27 |
2023-08-12 |
human |
| Hannes Hentze, Ingo Schmitz, Markus Latta, Andreas Krueger, Peter H Krammer, Albrecht Wende. Glutathione dependence of caspase-8 activation at the death-inducing signaling complex. The Journal of biological chemistry. vol 277. issue 7. 2002-03-21. PMID:11734564. |
apoptosis triggered by the death receptor cd95 (apo-1 or fas) is pivotal for the homeostasis of the immune system. |
2002-03-21 |
2023-08-12 |
Not clear |
| Stamatis Adamopoulos, John Parissis, Dimitrios Karatzas, Christos Kroupis, Michael Georgiadis, George Karavolias, John Paraskevaidis, Katerina Koniavitou, Andrew J S Coats, Dimitrios Th Kremastino. Physical training modulates proinflammatory cytokines and the soluble Fas/soluble Fas ligand system in patients with chronic heart failure. Journal of the American College of Cardiology. vol 39. issue 4. 2002-03-21. PMID:11849865. |
we sought to investigate the effects of physical training on circulating proinflammatory cytokines and the soluble apoptosis mediators fas (sfas) and fas ligand (sfasl) in patients with chronic heart failure (chf). |
2002-03-21 |
2023-08-12 |
Not clear |
| Ugochukwu C Nzeako, Maria Eugenia Guicciardi, Jung-Hwan Yoon, Steven F Bronk, Gregory J Gore. COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells. Hepatology (Baltimore, Md.). vol 35. issue 3. 2002-03-21. PMID:11870367. |
however, many human cholangiocarcinomas express fas, suggesting these cancers have developed mechanisms to inhibit fas-mediated apoptosis. |
2002-03-21 |
2023-08-12 |
human |
| Ugochukwu C Nzeako, Maria Eugenia Guicciardi, Jung-Hwan Yoon, Steven F Bronk, Gregory J Gore. COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells. Hepatology (Baltimore, Md.). vol 35. issue 3. 2002-03-21. PMID:11870367. |
prostaglandin e2 reduced apoptosis and mitochondrial depolarization after treatment with the fas agonist ch-11. |
2002-03-21 |
2023-08-12 |
human |
| H Kimura, H Minakami, A Shoj. Ultraviolet B irradiation modulates susceptibility to tumour necrosis factor-alpha-induced apoptosis via induction of death receptors in murine fibroblasts. Cell biology international. vol 25. issue 12. 2002-03-19. PMID:11748915. |
these results suggest that uvb irradiation modulates susceptibility to tnf-alpha-induced apoptosis through the induction of tnfrs, fas, and fas-l in murine fibroblasts. |
2002-03-19 |
2023-08-12 |
Not clear |
| C D Riffkin, A Z Gray, C J Hawkins, C W Chow, D M Ashle. Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction. Neuro-oncology. vol 3. issue 4. 2002-03-15. PMID:11584892. |
ex vivo pediatric brain tumors express fas (cd95) and fasl (cd95l) and are resistant to apoptosis induction. |
2002-03-15 |
2023-08-12 |
Not clear |
| C D Riffkin, A Z Gray, C J Hawkins, C W Chow, D M Ashle. Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction. Neuro-oncology. vol 3. issue 4. 2002-03-15. PMID:11584892. |
despite the presence of fas, all the specimens analyzed demonstrated a high degree of resistance to fas-mediated apoptosis. |
2002-03-15 |
2023-08-12 |
Not clear |
| C D Riffkin, A Z Gray, C J Hawkins, C W Chow, D M Ashle. Ex vivo pediatric brain tumors express Fas (CD95) and FasL (CD95L) and are resistant to apoptosis induction. Neuro-oncology. vol 3. issue 4. 2002-03-15. PMID:11584892. |
the results suggest that fas expression may be a general feature of tumors of the cns and that a significant degree of resistance to fas-mediated apoptosis may exist in ex vivo pediatric brain tumor specimens. |
2002-03-15 |
2023-08-12 |
Not clear |
| Takao Kataoka, Mika Ito, Ralph C Budd, Jürg Tschopp, Kazuo Naga. Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells. Experimental cell research. vol 273. issue 2. 2002-03-15. PMID:11822881. |
the murine thymoma cell line el-4 was resistant to fas ligand (fasl)-induced apoptosis by constitutive expression of flip (l). |
2002-03-15 |
2023-08-12 |
Not clear |
| Satoshi Ohno, Mitsuo Tachibana, Toshiyuki Fujii, Shuhei Ueda, Hirofumi Kubota, Naofumi Nagasu. Role of stromal collagen in immunomodulation and prognosis of advanced gastric carcinoma. International journal of cancer. vol 97. issue 6. 2002-03-15. PMID:11857352. |
tissue specimens from 84 advanced gastric carcinoma patients who had undergone a curative resection were evaluated for host immune status (cd8+ t cells), tumor stromal reaction (azan staining), tumor fas ligand expression and incidence of tumor cell apoptosis (by tunel). |
2002-03-15 |
2023-08-12 |
Not clear |
| T Komata, S Koga, S Hirohata, M Takakura, I M Germano, M Inoue, S Kyo, S Kondo, Y Kond. A novel treatment of human malignant gliomas in vitro and in vivo: FADD gene transfer under the control of the human telomerase reverse transcriptase gene promoter. International journal of oncology. vol 19. issue 5. 2002-03-13. PMID:11605003. |
over-expression of fadd induces apoptosis in the cells regardless of fas expression on the cell surface. |
2002-03-13 |
2023-08-12 |
human |