| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G M Kasof, J J Lu, D Liu, B Speer, K N Mongan, B C Gomes, M V Lorenz. Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. Oncogene. vol 20. issue 55. 2002-01-10. PMID:11753679. |
expression of a dominant negative mutant of fadd failed to protect from dr6-mediated apoptosis indicating that unlike tnfr1 and fas, dr6 induced apoptosis via a fadd-independent mechanism. |
2002-01-10 |
2023-08-12 |
Not clear |
| S K Jo, S Y Lee, S Y Han, D R Cha, W Y Cho, H K Kim, N H Wo. alpha-Melanocyte stimulating hormone (MSH) decreases cyclosporine a induced apoptosis in cultured human proximal tubular cells. Journal of Korean medical science. vol 16. issue 5. 2002-01-03. PMID:11641530. |
csa induced apoptosis in cultured tubular epithelial cells demonstrated by increased number of tunel positive cells and it was accompanied by a significant increase in fas mrna and fas ligand protein expressions. |
2002-01-03 |
2023-08-12 |
human |
| S K Jo, S Y Lee, S Y Han, D R Cha, W Y Cho, H K Kim, N H Wo. alpha-Melanocyte stimulating hormone (MSH) decreases cyclosporine a induced apoptosis in cultured human proximal tubular cells. Journal of Korean medical science. vol 16. issue 5. 2002-01-03. PMID:11641530. |
in alpha-msh co-treated cells, apoptosis markedly decreased with downregulation of fas, fas ligand and fadd expressions and also the cleavage product of parp. |
2002-01-03 |
2023-08-12 |
human |
| S K Jo, S Y Lee, S Y Han, D R Cha, W Y Cho, H K Kim, N H Wo. alpha-Melanocyte stimulating hormone (MSH) decreases cyclosporine a induced apoptosis in cultured human proximal tubular cells. Journal of Korean medical science. vol 16. issue 5. 2002-01-03. PMID:11641530. |
in conclusion, these data suggest that tubular cell apoptosis mediated by fas system may play a role in tubular atrophy in chronic csa nephrotoxicity and pretreatment of alpha-msh may have a some inhibitory effect on csa induced tubular cell apoptosis. |
2002-01-03 |
2023-08-12 |
human |
| J Majo, H Ghezzo, M G Cosi. Lymphocyte population and apoptosis in the lungs of smokers and their relation to emphysema. The European respiratory journal. vol 17. issue 5. 2002-01-02. PMID:11488331. |
anti-cd95 monoclonal antibodies and in situ end-labelling techniques were used to detect fas expression and apoptosis. |
2002-01-02 |
2023-08-12 |
human |
| Y Z Zhu, Y C Zhu, Z J Wang, Q Lu, H S Lee, T Unge. Time-dependent apoptotic development and pro-apoptotic genes expression in rat heart after myocardial infarction. Japanese journal of pharmacology. vol 86. issue 3. 2002-01-02. PMID:11488438. |
bax gene expression was increased at 12 h after mi and peaked at 24 h. fas gene started to over-express at 12 h after mi as well but it reached maximum at 72 h. in the mi groups, strongest staining of apoptosis was detected in rats 3 days post operation. |
2002-01-02 |
2023-08-12 |
rat |
| A M Hohlbaum, M S Gregory, S T Ju, A Marshak-Rothstei. Fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 11. 2002-01-02. PMID:11714783. |
fas ligand engagement of resident peritoneal macrophages in vivo induces apoptosis and the production of neutrophil chemotactic factors. |
2002-01-02 |
2023-08-12 |
mouse |
| J van der Werff ten Bosch, J Otten, K Thieleman. Autoimmune lymphoproliferative syndrome type III, an indefinite disorder. Leukemia & lymphoma. vol 41. issue 5-6. 2001-12-31. PMID:11378568. |
although the pathogenesis is not fully understood, deficient fas mediated apoptosis appears to be an important factor. |
2001-12-31 |
2023-08-12 |
Not clear |
| M C Lee, J S Lee, M J Lee, J H Lee, H I Ki. Fas mediates apoptosis in steroid-induced myopathy of rats. Neuropathology and applied neurobiology. vol 27. issue 5. 2001-12-31. PMID:11679091. |
fas mediates apoptosis in steroid-induced myopathy of rats. |
2001-12-31 |
2023-08-12 |
rat |
| M C Lee, J S Lee, M J Lee, J H Lee, H I Ki. Fas mediates apoptosis in steroid-induced myopathy of rats. Neuropathology and applied neurobiology. vol 27. issue 5. 2001-12-31. PMID:11679091. |
these findings indicate that ta can induce apoptosis in differentiated skeletal muscles, and fas antigen might be partly related to apoptotic muscle death in steroid-induced myopathy. |
2001-12-31 |
2023-08-12 |
rat |
| B Malassagne, P J Ferret, R Hammoud, M Tulliez, S Bedda, H Trébéden, P Jaffray, Y Calmus, B Weill, F Batteu. The superoxide dismutase mimetic MnTBAP prevents Fas-induced acute liver failure in the mouse. Gastroenterology. vol 121. issue 6. 2001-12-31. PMID:11729124. |
acute liver failure (alf) of viral origin results from massive hepatocyte apoptosis induced by the interaction between fas expressed on hepatocytes and fas ligand on activated t lymphocytes. |
2001-12-31 |
2023-08-12 |
mouse |
| N I Sharova, A K Dzutsev, M M Litvina, G N Pleskovskaya, T Y Kharchenko, A A Yarili. Thymic epithelial cells induce Fas-independent activation apoptosis of thymocytes. Immunology letters. vol 78. issue 3. 2001-12-26. PMID:11578696. |
thymocytes of mice mrl-lpr/lpr bearing mutant form of gene fas were sensitive to apoptosis induction in co-culture with tec in the same degree as thymocytes of mice bearing fas gene of wild type. |
2001-12-26 |
2023-08-12 |
mouse |
| H Marusawa, M Hijikata, K Watashi, T Chiba, K Shimotohn. Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte derived cell lines. Microbiology and immunology. vol 45. issue 6. 2001-12-21. PMID:11497224. |
notably, inactivation of nf-kappab by the production of ikappab-alpha protein made these cells more susceptible to apoptosis induced by fas stimulation. |
2001-12-21 |
2023-08-12 |
human |
| H Marusawa, M Hijikata, K Watashi, T Chiba, K Shimotohn. Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte derived cell lines. Microbiology and immunology. vol 45. issue 6. 2001-12-21. PMID:11497224. |
these findings suggest the involvement of nf-kappab in suppression of fas-mediated apoptosis in human hepatocyte derived cell lines, in which concomitant activation of this transcriptional factor was observed through the stimulation of fas signaling. |
2001-12-21 |
2023-08-12 |
human |
| J Rho, S Gong, N Kim, Y Cho. TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo. Molecular and cellular biology. vol 21. issue 24. 2001-12-21. PMID:11713273. |
tdag51 has been shown to play critical roles in the up-regulation of fas gene expression and t-cell apoptosis in vitro. |
2001-12-21 |
2023-08-12 |
mouse |
| J Rho, S Gong, N Kim, Y Cho. TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo. Molecular and cellular biology. vol 21. issue 24. 2001-12-21. PMID:11713273. |
although tdag51 is required for up-regulation of fas expression in t-cell hybridomas, tdag51-/- mice expressed normal levels of fas and had normal t-cell apoptosis. |
2001-12-21 |
2023-08-12 |
mouse |
| J Rho, S Gong, N Kim, Y Cho. TDAG51 is not essential for Fas/CD95 regulation and apoptosis in vivo. Molecular and cellular biology. vol 21. issue 24. 2001-12-21. PMID:11713273. |
therefore, we conclude that tdag51 is not essential for fas up-regulation and t-cell apoptosis in vivo. |
2001-12-21 |
2023-08-12 |
mouse |
| S Y Lin, Y T Chang, J D Liu, C H Yu, Y S Ho, Y H Lee, W S Le. Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells. Molecular carcinogenesis. vol 32. issue 2. 2001-12-20. PMID:11746819. |
pretreatment of the cells with zb4 (which disrupts the fas response mechanism) also decreased the subsequent magnolol-induced caspase-8 activation and reduced the occurrence of apoptosis. |
2001-12-20 |
2023-08-12 |
human |
| S Y Lin, Y T Chang, J D Liu, C H Yu, Y S Ho, Y H Lee, W S Le. Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells. Molecular carcinogenesis. vol 32. issue 2. 2001-12-20. PMID:11746819. |
we interpreted these findings to indicate that the above-listed sequence of intracellular events led to the apoptosis seen in hep g2 cells and that [ca(2+)](i), cyto c, and fas function as intracellular signals to coordinate those events. |
2001-12-20 |
2023-08-12 |
human |
| P Reddy, T Teshima, M Kukuruga, R Ordemann, C Liu, K Lowler, J L Ferrar. Interleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosis. The Journal of experimental medicine. vol 194. issue 10. 2001-12-13. PMID:11714750. |
administration of il-18 attenuated early donor t cell expansion and was associated with increased fas expression and greater apoptosis of donor t cells. |
2001-12-13 |
2023-08-12 |
mouse |