| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Screpanti, R P Wallin, H G Ljunggren, A Grandie. A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 4. 2001-12-05. PMID:11489989. |
when injected in immunocompetent recipients, rma-s cells up-regulate fas, rendering in vivo-passed mock-transduced cells sensitive to fas-mediated apoptosis. |
2001-12-05 |
2023-08-12 |
Not clear |
| I W Park, C K Ullrich, E Schoenberger, R K Ganju, J E Groopma. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 5. 2001-12-05. PMID:11509621. |
this apoptosis occurred without induction of either fas or tnf, known mediators of programmed cell death. |
2001-12-05 |
2023-08-12 |
human |
| I W Park, C K Ullrich, E Schoenberger, R K Ganju, J E Groopma. HIV-1 Tat induces microvascular endothelial apoptosis through caspase activation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 5. 2001-12-05. PMID:11509621. |
taken together, these data demonstrate that hiv-1 tat is able to activate apoptosis in microvascular endothelium by a mechanism distinct from tnf secretion or the fas pathway. |
2001-12-05 |
2023-08-12 |
human |
| P M Yao, I Taba. Free cholesterol loading of macrophages is associated with widespread mitochondrial dysfunction and activation of the mitochondrial apoptosis pathway. The Journal of biological chemistry. vol 276. issue 45. 2001-12-05. PMID:11533046. |
we recently showed that fc loading of macrophages causes apoptosis, approximately 50% of which is mediated by activation of cell-surface fasl and triggering of the fas pathway (yao, p. m., and tabas, i. |
2001-12-05 |
2023-08-12 |
mouse |
| B Selam, U A Kayisli, N Mulayim, A Aric. Regulation of Fas ligand expression by estradiol and progesterone in human endometrium. Biology of reproduction. vol 65. issue 4. 2001-12-05. PMID:11566716. |
fas ligand (fasl) is one of the mediators of apoptosis in differentiated cells and in embryonic development. |
2001-12-05 |
2023-08-12 |
human |
| B Selam, U A Kayisli, N Mulayim, A Aric. Regulation of Fas ligand expression by estradiol and progesterone in human endometrium. Biology of reproduction. vol 65. issue 4. 2001-12-05. PMID:11566716. |
interaction of fasl with its receptor, fas, induces apoptosis through autocrine and paracrine signaling. |
2001-12-05 |
2023-08-12 |
human |
| A Gruslin, Q Qiu, B K Tsan. Influence of maternal smoking on trophoblast apoptosis throughout development: possible involvement of Xiap regulation. Biology of reproduction. vol 65. issue 4. 2001-12-05. PMID:11566739. |
in this study, we examined the influence of maternal smoking on trophoblast apoptosis throughout development and correlated those findings with changes in expression of x-linked inhibitor of apoptosis protein (xiap) as well as fas and fas ligand (fasl). |
2001-12-05 |
2023-08-12 |
Not clear |
| S Santourlidis, U Warskulat, A R Florl, S Maas, T Pulte, J Fischer, W Müller, W A Schul. Hypermethylation of the tumor necrosis factor receptor superfamily 6 (APT1, Fas, CD95/Apo-1) gene promoter at rel/nuclear factor kappaB sites in prostatic carcinoma. Molecular carcinogenesis. vol 32. issue 1. 2001-12-05. PMID:11568974. |
the fas (cd95, apo-1) protein encoded by the tnfrsf6 gene is an important mediator of apoptosis, which also is downregulated in different types of human carcinoma. |
2001-12-05 |
2023-08-12 |
mouse |
| J J Bleesing, M R Brown, S E Straus, J K Dale, R M Siegel, M Johnson, M J Lenardo, J M Puck, T A Fleishe. Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome. Blood. vol 98. issue 8. 2001-12-05. PMID:11588044. |
because quantitative defects in apoptosis were similar in mutation-positive relatives regardless of the presence of clinical alps, factors, other than modifiers of the fas apoptosis pathway, leading to these distinctive immunophenotypic profiles most likely contribute to disease penetrance in alps. |
2001-12-05 |
2023-08-12 |
Not clear |
| R F Abu-Helu, I D Dimitriou, E K Kapsogeorgou, H M Moutsopoulos, M N Manoussaki. Induction of salivary gland epithelial cell injury in Sjogren's syndrome: in vitro assessment of T cell-derived cytokines and Fas protein expression. Journal of autoimmunity. vol 17. issue 2. 2001-12-05. PMID:11591123. |
sjogren's syndrome (ss) is an exocrinopathy characterized by t cell infiltrates, salivary gland epithelial cell (sgec) apoptosis and high fas and fasl expression. |
2001-12-05 |
2023-08-12 |
Not clear |
| R F Abu-Helu, I D Dimitriou, E K Kapsogeorgou, H M Moutsopoulos, M N Manoussaki. Induction of salivary gland epithelial cell injury in Sjogren's syndrome: in vitro assessment of T cell-derived cytokines and Fas protein expression. Journal of autoimmunity. vol 17. issue 2. 2001-12-05. PMID:11591123. |
surface co-expression of fas and fasl was not associated with spontaneous fratricide apoptosis. |
2001-12-05 |
2023-08-12 |
Not clear |
| R F Abu-Helu, I D Dimitriou, E K Kapsogeorgou, H M Moutsopoulos, M N Manoussaki. Induction of salivary gland epithelial cell injury in Sjogren's syndrome: in vitro assessment of T cell-derived cytokines and Fas protein expression. Journal of autoimmunity. vol 17. issue 2. 2001-12-05. PMID:11591123. |
dexamethasone inhibited the upregulation of fas and fasl by ifn-gamma and the induction of sgec apoptosis and detachment by anti-fas mab or ifn-gamma. |
2001-12-05 |
2023-08-12 |
Not clear |
| S J Lin, L Y Wang, Y J Huang, M L Ku. Effect of interleukin (IL)-12 and IL-15 on apoptosis and proliferation of umbilical cord blood mononuclear cells. Bone marrow transplantation. vol 28. issue 5. 2001-12-05. PMID:11593316. |
the results of our study indicated that: (1) the combination of il-12+il-15 resulted in a greater degree of cb and apb apoptosis than either cytokine alone; (2) the level of both spontaneous and cytokine-induced apoptosis by il-12 and/or il-15 are greater in cb mncs than in apb mncs using tunel assays; (3) il-15 is superior to il-12 in enhancing the proliferative response in cb and apb mncs; (4) the combination of il-12+il-15, but not either cytokine alone, significantly enhanced apoptosis in cd8+ and cd56+ cb subsets, but not in cd4+ cb subsets; (5) il-12 or il-15 alone resulted in increased proliferation in cd4+, cd8+ and cd56+ cb subsets, with il-12+il-15 producing the greatest increase of proliferation in all three cb subsets; and (6) il-15 and/or il-12 significantly upregulate fas (cd95) expression on cb t and nk cells. |
2001-12-05 |
2023-08-12 |
Not clear |
| G Roué, L Lancry, F Duquesne, V Salaün, X Troussard, B Sol. Upstream mediators of the Fas apoptotic transduction pathway are defective in B-chronic lymphocytic leukemia. Leukemia research. vol 25. issue 11. 2001-12-05. PMID:11597732. |
fas triggering was inefficient in inducing apoptosis whatever the number of fas-positive b-cells, the amount of fas receptors. |
2001-12-05 |
2023-08-12 |
Not clear |
| Y Song, G Xu, L Zhan. [Transfection of Fas(CD95) gene into HL-60 cell and its role in rhG-CSF-induced apoptosis]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 20. issue 5. 2001-12-05. PMID:11601212. |
[transfection of fas(cd95) gene into hl-60 cell and its role in rhg-csf-induced apoptosis]. |
2001-12-05 |
2023-08-12 |
Not clear |
| Y Song, G Xu, L Zhan. [Transfection of Fas(CD95) gene into HL-60 cell and its role in rhG-CSF-induced apoptosis]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. vol 20. issue 5. 2001-12-05. PMID:11601212. |
to explore the role of fas gene in rhg-csf-induced apoptosis. |
2001-12-05 |
2023-08-12 |
Not clear |
| R Levy, I Seifer-Akni. [Apoptosis during spermatogenesis and in ejaculated spermatozoa: importance for fertilization]. Annales de biologie clinique. vol 59. issue 5. 2001-12-05. PMID:11602383. |
however, the analysis of other molecular markers of apoptosis (fas, annexine v.) is now necessary to assess the role of apoptosis in human ejaculated sperm cells. |
2001-12-05 |
2023-08-12 |
human |
| P Hubert, S L Giannini, A Vanderplasschen, E Franzen-Detrooz, N Jacobs, J Boniver, P Delvenn. Dendritic cells induce the death of human papillomavirus-transformed keratinocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 13. 2001-12-05. PMID:11641258. |
furthermore, although fasl and fas were detected on dc and hpv+ cell lines, respectively, functional analysis revealed that this pathway is not responsible for the apoptosis induced by the dc. |
2001-12-05 |
2023-08-12 |
human |
| A M Owyang, J R Tumang, B R Schram, C Y Hsia, T W Behrens, T L Rothstein, H C Lio. c-Rel is required for the protection of B cells from antigen receptor-mediated, but not Fas-mediated, apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 9. 2001-12-05. PMID:11673501. |
the fas apoptosis inhibitor molecule and flice inhibitory protein (c-flip) proteins are up-regulated normally in c-rel(-/-) b cells, and these two molecules may play a more physiological role in the fas pathway. |
2001-12-05 |
2023-08-12 |
mouse |
| B Z Packard, A Komoriya, T M Brotz, P A Henkar. Caspase 8 activity in membrane blebs after anti-Fas ligation. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 9. 2001-12-05. PMID:11673515. |
previous studies of thymocyte apoptosis using a series of cell-permeable fluorogenic peptide substrates showed that fas cross-linking triggered a caspase cascade in which cleavage of the ietdase (caspase 8-selective) substrate was the earliest caspase activity measured by flow cytometry. |
2001-12-05 |
2023-08-12 |
Not clear |