| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A J Belanger, A Scaria, H Lu, J A Sullivan, S H Cheng, R J Gregory, C Jian. Fas ligand/Fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action. Cardiovascular research. vol 51. issue 4. 2001-11-01. PMID:11530108. |
fas ligand/fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action. |
2001-11-01 |
2023-08-12 |
human |
| A J Belanger, A Scaria, H Lu, J A Sullivan, S H Cheng, R J Gregory, C Jian. Fas ligand/Fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action. Cardiovascular research. vol 51. issue 4. 2001-11-01. PMID:11530108. |
this study aimed to determine the mode of action of fas ligand (fasl)/fas at mediating apoptosis so as to evaluate the potential of fasl in gene therapy for restenosis. |
2001-11-01 |
2023-08-12 |
human |
| M Stella, P Cassano, D Bollero, A Clemente, G Giori. Toxic epidermal necrolysis treated with intravenous high-dose immunoglobulins: our experience. Dermatology (Basel, Switzerland). vol 203. issue 1. 2001-11-01. PMID:11549799. |
toxic epidermal necrolysis (ten) is a rare severe acute exfoliative drug-induced skin disorder which has recently been ascribed to alterations in the control of keratinocyte apoptosis, mediated by an interaction between the cell surface death receptor fas and its respective ligand. |
2001-11-01 |
2023-08-12 |
human |
| A Ghose, J Fleming, P R Harriso. Selenium and signal transduction: roads to cell death and anti-tumour activity. BioFactors (Oxford, England). vol 14. issue 1-4. 2001-11-01. PMID:11568449. |
induction of fas ligand was associated with selenium-induced apoptosis. |
2001-11-01 |
2023-08-12 |
Not clear |
| H C Hsu, H G Zhang, G G Song, J Xie, D Liu, P A Yang, M Fleck, W Wintersberger, T Zhou, C K Edwards, J D Mount. Defective Fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to Mycoplasma pulmonis infection. Arthritis and rheumatism. vol 44. issue 9. 2001-11-01. PMID:11592380. |
defective fas ligand-mediated apoptosis predisposes to development of a chronic erosive arthritis subsequent to mycoplasma pulmonis infection. |
2001-11-01 |
2023-08-12 |
Not clear |
| S J Meech, R Edelson, P Walsh, D A Norris, R C Duk. Reversible resistance to apoptosis in cutaneous T cell lymphoma. Annals of the New York Academy of Sciences. vol 941. 2001-11-01. PMID:11594582. |
factors leading to the resistance of apoptosis in ctcl and new therapeutic approaches for reversing this resistance will be discussed, including the important role that the fas death pathway may play in the pathogenesis and treatment of ctcl. |
2001-11-01 |
2023-08-12 |
Not clear |
| L Boldrini, P Faviana, F Pistolesi, S Gisfredi, D Di Quirico, M Lucchi, A Mussi, C A Angeletti, F Baldinotti, A Fogli, P Simi, F Basolo, G Fontanin. Alterations of Fas (APO-1/CD 95) gene and its relationship with p53 in non small cell lung cancer. Oncogene. vol 20. issue 45. 2001-11-01. PMID:11641789. |
the ligand for fas induces apoptosis by interacting with a transmembrane cell surface fas receptor. |
2001-11-01 |
2023-08-12 |
human |
| L Boldrini, P Faviana, F Pistolesi, S Gisfredi, D Di Quirico, M Lucchi, A Mussi, C A Angeletti, F Baldinotti, A Fogli, P Simi, F Basolo, G Fontanin. Alterations of Fas (APO-1/CD 95) gene and its relationship with p53 in non small cell lung cancer. Oncogene. vol 20. issue 45. 2001-11-01. PMID:11641789. |
the key role of the fas system has been studied mostly in the immune system, but fas mutations, one of the possible mechanisms for resistance to apoptosis signaling, may be involved in the pathogenesis of non-lymphoid malignancies as well. |
2001-11-01 |
2023-08-12 |
human |
| I Peták, J A Houghto. Shared pathways: death receptors and cytotoxic drugs in cancer therapy. Pathology oncology research : POR. vol 7. issue 2. 2001-10-25. PMID:11458271. |
the involvement of the fas signaling pathway in chemotherapy-induced apoptosis has been the most extensively studied, with the current emergence of information on the trail signaling pathway. |
2001-10-25 |
2023-08-12 |
Not clear |
| K Fujii, Y Fujii, S Hubscher, Y Tanak. CD44 is the physiological trigger of Fas up-regulation on rheumatoid synovial cells. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 3. 2001-10-25. PMID:11466334. |
in this study, we propose a novel function for cd44 using synovial cells from rheumatoid arthritis (ra) patients and demonstrated that cd44 cross-linking augmented fas expression and subsequent fas-mediated apoptosis of the cells: 1) cross-linking of cd44 on ra synovial cells markedly augmented fas expression and its mrna transcription; 2) engagement of cd44 up-regulated fas on the cells within 3 h, much more than il-1beta and tnf-alpha did; 3) the fas-mediated early apoptotic change of the cells was amplified by cd44 cross-linking; and 4) hyaluronan, especially when fragmented, also augmented fas-mediated early apoptosis of the cells. |
2001-10-25 |
2023-08-12 |
Not clear |
| K Fujii, Y Fujii, S Hubscher, Y Tanak. CD44 is the physiological trigger of Fas up-regulation on rheumatoid synovial cells. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 3. 2001-10-25. PMID:11466334. |
based on these findings, we postulate a new concept: that interaction of cd44 on ra synovial cells with hyaluronan fragments present in the surrounding extracellular matrix augments fas expression as well as fas-mediated apoptosis of synovial cells. |
2001-10-25 |
2023-08-12 |
Not clear |
| M J Lee, J S Lee, M C Le. Apoptosis of skeletal muscle on steroid-induced myopathy in rats. Journal of Korean medical science. vol 16. issue 4. 2001-10-25. PMID:11511793. |
these findings indicate that ta can induce apoptosis in differentiated skeletal muscles, and fas antigen might be partly related to apoptotic muscle death in steroid-induced myopathy. |
2001-10-25 |
2023-08-12 |
rat |
| D H Dockrel. Apoptotic cell death in the pathogenesis of infectious diseases. The Journal of infection. vol 42. issue 4. 2001-10-25. PMID:11545564. |
a number of different pathways induce hiv-associated cd4 t-lymphocyte apoptosis and apoptosis of uninfected bystander cells is particularly associated with increased susceptibility to fas. |
2001-10-25 |
2023-08-12 |
human |
| J Sträter, P Mölle. Fas (CD95)-mediated apoptosis in celiac disease. American journal of clinical pathology. vol 116. issue 4. 2001-10-25. PMID:11601145. |
fas (cd95)-mediated apoptosis in celiac disease. |
2001-10-25 |
2023-08-12 |
Not clear |
| M L Bajt, S L Vonderfecht, H Jaeschk. Differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and Fas receptor-mediated hepatocellular apoptosis. Toxicology and applied pharmacology. vol 175. issue 3. 2001-10-18. PMID:11559023. |
differential protection with inhibitors of caspase-8 and caspase-3 in murine models of tumor necrosis factor and fas receptor-mediated hepatocellular apoptosis. |
2001-10-18 |
2023-08-12 |
mouse |
| M Chakraborty, S G Qiu, K M Vasudevan, V M Rangneka. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer research. vol 61. issue 19. 2001-10-18. PMID:11585763. |
par-4 drives trafficking and activation of fas and fasl to induce prostate cancer cell apoptosis and tumor regression. |
2001-10-18 |
2023-08-12 |
Not clear |
| M Chakraborty, S G Qiu, K M Vasudevan, V M Rangneka. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer research. vol 61. issue 19. 2001-10-18. PMID:11585763. |
par-4 induced apoptosis of selective prostate cancer cells pc-3, du-145, and tsu-pr and caused tumor regression by inhibition of nf-kappab activity and cell membrane trafficking of fas and fasl that leads to the activation of the fas-fas-associated death domain-caspase-8 pro-death pathway. |
2001-10-18 |
2023-08-12 |
Not clear |
| M Chakraborty, S G Qiu, K M Vasudevan, V M Rangneka. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer research. vol 61. issue 19. 2001-10-18. PMID:11585763. |
neither fas pathway activation alone nor inhibition of nf-kappab activity with ikappab-super repressor was sufficient to induce apoptosis of prostate cancer cells. |
2001-10-18 |
2023-08-12 |
Not clear |
| M Chakraborty, S G Qiu, K M Vasudevan, V M Rangneka. Par-4 drives trafficking and activation of Fas and Fasl to induce prostate cancer cell apoptosis and tumor regression. Cancer research. vol 61. issue 19. 2001-10-18. PMID:11585763. |
on the other hand, prostate cancer cells lncap or normal prostatic epithelial cells that were resistant to apoptosis by par-4 did not show fas or fasl trafficking. |
2001-10-18 |
2023-08-12 |
Not clear |
| A W Tong, M H Papayoti, G Netto, D T Armstrong, G Ordonez, J M Lawson, M J Ston. Growth-inhibitory effects of CD40 ligand (CD154) and its endogenous expression in human breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 7. issue 3. 2001-10-11. PMID:11297266. |
thirty-one and 27% of gp39-treated t47d and bt-20 cells underwent apoptosis, respectively, as compared with 56 and 65% from the same cell lines after treatment with the fas agonistic antibody ch-11. |
2001-10-11 |
2023-08-12 |
human |