| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
fas aggregation does not correlate with fas-mediated apoptosis. |
2001-09-20 |
2023-08-12 |
human |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
cross-linking of cell surface fas molecules by fas ligand or by agonistic anti-fas abs induces cell death by apoptosis. |
2001-09-20 |
2023-08-12 |
human |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
tlck treatment had no effect on fas expression levels on the cell surface, and neither promoted death-inducing signaling complex formation nor decreased expression levels of cellular inhibitors of apoptosis (flice inhibitory protein, x chromosome-linked inhibitor of apoptosis, and bcl-2). |
2001-09-20 |
2023-08-12 |
human |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
fas aggregation is often considered to be required for fas-mediated apoptosis. |
2001-09-20 |
2023-08-12 |
human |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
however, sensitization of cells to fas-mediated apoptosis by tlck or other agents (cycloheximide, protein kinase c inhibitors) causes less fas aggregation during the apoptotic process compared with that in nonsensitized cells. |
2001-09-20 |
2023-08-12 |
human |
| Y Lee, E Shacte. Fas aggregation does not correlate with Fas-mediated apoptosis. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418635. |
these results show that fas aggregation and fas-mediated apoptosis are not directly correlated and may even be inversely correlated. |
2001-09-20 |
2023-08-12 |
human |
| Y Osawa, Y Banno, M Nagaki, D A Brenner, T Naiki, Y Nozawa, S Nakashima, H Moriwak. TNF-alpha-induced sphingosine 1-phosphate inhibits apoptosis through a phosphatidylinositol 3-kinase/Akt pathway in human hepatocytes. Journal of immunology (Baltimore, Md. : 1950). vol 167. issue 1. 2001-09-20. PMID:11418646. |
furthermore, apoptosis mediated by fas ligand (fasl) involving akt activation also was potentiated by dms pretreatment in hc cells. |
2001-09-20 |
2023-08-12 |
mouse |
| R Guillot, A F Bringuier, B Porokhov, P J Guillausseau, G Feldman. Increased levels of soluble Fas in serum from diabetic patients with neuropathy. Diabetes & metabolism. vol 27. issue 3. 2001-09-20. PMID:11431596. |
the aim of this study was to investigate circulating soluble fas (sfas) and fas ligand (sfasl), two transmembrane glycoproteins involved in apoptosis, in the serum of diabetic patients. |
2001-09-20 |
2023-08-12 |
Not clear |
| D Decaudin, A Beurdeley-Thomas, F Nemati, L Miccoli, P Pouillart, Y Bourgeois, R B Gonçalves, D Rouillard, M F Poupo. Distinct experimental efficacy of anti-Fas/APO-1/CD95 receptor antibody in human tumors. Experimental cell research. vol 268. issue 2. 2001-09-20. PMID:11478842. |
ligation of the fas receptor (fasr) is a key step in apoptosis induction. |
2001-09-20 |
2023-08-12 |
mouse |
| X Zhong, T J Schneider, D S Cabral, T J Donohoe, T L Rothstei. An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain. Molecular immunology. vol 38. issue 1. 2001-09-20. PMID:11483211. |
an alternatively spliced long form of fas apoptosis inhibitory molecule (faim) with tissue-specific expression in the brain. |
2001-09-20 |
2023-08-12 |
human |
| X Zhong, T J Schneider, D S Cabral, T J Donohoe, T L Rothstei. An alternatively spliced long form of Fas apoptosis inhibitory molecule (FAIM) with tissue-specific expression in the brain. Molecular immunology. vol 38. issue 1. 2001-09-20. PMID:11483211. |
the gene encoding fas apoptosis inhibitory molecule (faim) was cloned by differential display using rna obtained from fas-resistant and fas-sensitive primary murine b lymphocytes. |
2001-09-20 |
2023-08-12 |
human |
| N I Tapinos, M Polihronis, A G Tzioufas, F N Skopoul. Immunopathology of Sjögren's syndrome. Annales de medecine interne. vol 149. issue 1. 2001-09-20. PMID:11490512. |
the characteristic destruction of epithelial cells of sjögren's syndrome patients is probably due to activation of several apoptotic pathways since epithelial cells express different apoptosis related molecules such as fas, fasl, bax, while mononuclear cells express perforin and granzymes. |
2001-09-20 |
2023-08-12 |
Not clear |
| B S Youn, Y J Kim, C Mantel, K Y Yu, H E Broxmeye. Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction. Blood. vol 98. issue 4. 2001-09-20. PMID:11493434. |
when molt4 cells, which expressed fas as well as cxcr4, were stimulated with cycloheximide (chx), an agonistic anti-fas antibody, or a combination of these, the cells rapidly underwent apoptosis. |
2001-09-20 |
2023-08-12 |
human |
| A Di Sabatino, R Ciccocioppo, S D'Alò, R Parroni, D Millimaggi, M G Cifone, G R Corazz. Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease. Gut. vol 49. issue 3. 2001-09-20. PMID:11511560. |
intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in fas based cytotoxicity in coeliac disease. |
2001-09-20 |
2023-08-12 |
Not clear |
| J J Bleesing, M R Brown, J K Dale, S E Straus, M J Lenardo, J M Puck, T P Atkinson, T A Fleishe. TcR-alpha/beta(+) CD4(-)CD8(-) T cells in humans with the autoimmune lymphoproliferative syndrome express a novel CD45 isoform that is analogous to murine B220 and represents a marker of altered O-glycan biosynthesis. Clinical immunology (Orlando, Fla.). vol 100. issue 3. 2001-09-20. PMID:11513545. |
autoimmune lymphoproliferative syndrome (alps), caused by inherited defects in apoptosis secondary to mutations in genes encoding fas/cd95/apo-1 and fas ligand (fasl)/cd95l, is characterized by nonmalignant lymphadenopathy and splenomegaly, increased t cell receptor alpha/beta(+) cd4(-)cd8(-) t cells (alpha/beta(+) double-negative t cells [alpha/beta(+)-dnt cells]), autoimmunity, hypergammaglobulinemia, and cytokine abnormalities. |
2001-09-20 |
2023-08-12 |
mouse |
| S Gilbert, A Loranger, N Daigle, N Marcea. Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. The Journal of cell biology. vol 154. issue 4. 2001-09-20. PMID:11514590. |
here, we report that k8-null mouse hepatocytes in primary culture and in vivo are three- to fourfold more sensitive than wild-type (wt) mouse hepatocytes to fas-mediated apoptosis after stimulation with jo2, an agonistic antibody of fas ligand. |
2001-09-20 |
2023-08-12 |
mouse |
| S Gilbert, A Loranger, N Daigle, N Marcea. Simple epithelium keratins 8 and 18 provide resistance to Fas-mediated apoptosis. The protection occurs through a receptor-targeting modulation. The Journal of cell biology. vol 154. issue 4. 2001-09-20. PMID:11514590. |
together, the results strongly suggest that simple epithelium k8/k18 provide resistance to fas-mediated apoptosis and that this protection occurs through a modulation of fas targeting to the cell surface. |
2001-09-20 |
2023-08-12 |
mouse |
| W Chen, W Jin, H Tian, P Sicurello, M Frank, J M Orenstein, S M Wah. Requirement for transforming growth factor beta1 in controlling T cell apoptosis. The Journal of experimental medicine. vol 194. issue 4. 2001-09-20. PMID:11514601. |
engagement of the t cell receptor enhanced this aberrant t cell apoptosis, as did signaling through either the death receptor fas or the tumor necrosis factor alpha receptor in peripheral t cells. |
2001-09-20 |
2023-08-12 |
mouse |
| S Fiorucci, E Distrutti, M N Ajuebor, A Mencarelli, R Mannucci, B Palazzetti, P Del Soldato, A Morelli, J L Wallac. NO-mesalamine protects colonic epithelial cells against apoptotic damage induced by proinflammatory cytokines. American journal of physiology. Gastrointestinal and liver physiology. vol 281. issue 3. 2001-09-20. PMID:11518677. |
nitric oxide (no) protects from apoptosis induced by fas and tnf-alpha. |
2001-09-20 |
2023-08-12 |
Not clear |
| A Pileggi, R D Molano, T Berney, P Cattan, C Vizzardelli, R Oliver, C Fraker, C Ricordi, R L Pastori, F H Bach, L Inverard. Heme oxygenase-1 induction in islet cells results in protection from apoptosis and improved in vivo function after transplantation. Diabetes. vol 50. issue 9. 2001-09-20. PMID:11522663. |
ho-1 upregulation was induced reproducibly with protoporphyrins and was correlated with protection from apoptosis induced in vitro with proinflammatory cytokines or fas engagement. |
2001-09-20 |
2023-08-12 |
Not clear |