| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H H Backus, D F Dukers, C J van Groeningen, W Vos, E Bloemena, D Wouters, J M van Riel, K Smid, G Giaccone, H M Pinedo, G J Peter. 5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology. vol 12. issue 2. 2001-09-13. PMID:11300326. |
5-fluorouracil induced fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients. |
2001-09-13 |
2023-08-12 |
Not clear |
| H H Backus, D F Dukers, C J van Groeningen, W Vos, E Bloemena, D Wouters, J M van Riel, K Smid, G Giaccone, H M Pinedo, G J Peter. 5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology. vol 12. issue 2. 2001-09-13. PMID:11300326. |
in vitro, thymidylate synthase (ts) inhibition by 5-fluorouracil (5-fu) induces thymineless apoptosis possibly via fas receptor fas ligand interactions and cell-cycle arrest. |
2001-09-13 |
2023-08-12 |
Not clear |
| X Q Fan, Y J Gu. Apoptosis in oncology. Cell research. vol 11. issue 1. 2001-09-13. PMID:11305320. |
apart from traditional therapies, inducing apoptosis of tumor cell by new methods employing death receptor ligands and making use of fas counterattack is also being developed. |
2001-09-13 |
2023-08-12 |
Not clear |
| K Kato, K Ohshima, K Anzai, J Suzumiya, M Kikuch. Elevated serum-soluble Fas ligand in histiocytic necrotizing lymphadenitis. International journal of hematology. vol 73. issue 1. 2001-09-13. PMID:11372760. |
recent studies have indicated that fas and perforin-based mechanisms seem to induce apoptosis in histiocytic necrotizing lymphadenitis (hnl). |
2001-09-13 |
2023-08-12 |
Not clear |
| W K Hofmann, S de Vos, K Tsukasaki, W Wachsman, G S Pinkus, J W Said, H P Koeffle. Altered apoptosis pathways in mantle cell lymphoma detected by oligonucleotide microarray. Blood. vol 98. issue 3. 2001-09-13. PMID:11468180. |
the fas-associated via death domain (fadd) gene that acts downstream of the fas cascade as a key gene to induce apoptosis was more than 10-fold down-regulated in mcl. |
2001-09-13 |
2023-08-12 |
Not clear |
| S Hayakawa, K Saeki, M Sazuka, Y Suzuki, Y Shoji, T Ohta, K Kaji, A Yuo, M Isemur. Apoptosis induction by epigallocatechin gallate involves its binding to Fas. Biochemical and biophysical research communications. vol 285. issue 5. 2001-09-13. PMID:11478767. |
apoptosis induction by epigallocatechin gallate involves its binding to fas. |
2001-09-13 |
2023-08-12 |
human |
| S Hayakawa, K Saeki, M Sazuka, Y Suzuki, Y Shoji, T Ohta, K Kaji, A Yuo, M Isemur. Apoptosis induction by epigallocatechin gallate involves its binding to Fas. Biochemical and biophysical research communications. vol 285. issue 5. 2001-09-13. PMID:11478767. |
the aim of this study was to examine the possibility that egcg-binding to fas triggers the fas-mediated apoptosis. |
2001-09-13 |
2023-08-12 |
human |
| S Hayakawa, K Saeki, M Sazuka, Y Suzuki, Y Shoji, T Ohta, K Kaji, A Yuo, M Isemur. Apoptosis induction by epigallocatechin gallate involves its binding to Fas. Biochemical and biophysical research communications. vol 285. issue 5. 2001-09-13. PMID:11478767. |
thus, the results suggest that egcg-binding to fas, presumably on the cell surface, triggers the fas-mediated apoptosis in u937 cells. |
2001-09-13 |
2023-08-12 |
human |
| T Hayashi, D L Faustma. Implications of altered apoptosis in diabetes mellitus and autoimmune disease. Apoptosis : an international journal on programmed cell death. vol 6. issue 1-2. 2001-09-06. PMID:11321039. |
in murine models of autoimmune lupus, mutations in cell death receptor cd95 (fas) and its ligand cd95l (fasl) have been identified; these errors create a lymphoid system resistant to apoptosis. |
2001-09-06 |
2023-08-12 |
mouse |
| C Giordano, P Richiusa, M Bagnasco, G Pizzolanti, F Di Blasi, M S Sbriglia, A Mattina, G Pesce, P Montagna, F Capone, G Misiano, A Scorsone, A Pugliese, A Galluzz. Differential regulation of Fas-mediated apoptosis in both thyrocyte and lymphocyte cellular compartments correlates with opposite phenotypic manifestations of autoimmune thyroid disease. Thyroid : official journal of the American Thyroid Association. vol 11. issue 3. 2001-09-06. PMID:11327614. |
to gain further insight into such mechanisms we performed an exhaustive comparative analysis of the expression of key molecules regulating cell death (fas, fas ligand [fasl], bcl-2) and apoptosis in both thyrocytes and thyroid infiltrating lymphocytes (tils) from patients with either gd or ht. |
2001-09-06 |
2023-08-12 |
Not clear |
| C Giordano, P Richiusa, M Bagnasco, G Pizzolanti, F Di Blasi, M S Sbriglia, A Mattina, G Pesce, P Montagna, F Capone, G Misiano, A Scorsone, A Pugliese, A Galluzz. Differential regulation of Fas-mediated apoptosis in both thyrocyte and lymphocyte cellular compartments correlates with opposite phenotypic manifestations of autoimmune thyroid disease. Thyroid : official journal of the American Thyroid Association. vol 11. issue 3. 2001-09-06. PMID:11327614. |
the patterns of apoptosis observed were consistent with the regulation of fas, fasl, and bcl-2 described above. |
2001-09-06 |
2023-08-12 |
Not clear |
| M Di Renzo, D Serrano, Z Zhou, I George, K Becker, C Cunningham-Rundle. Enhanced T cell apoptosis in common variable immunodeficiency: negative role of the fas/fasligand system and of the Bcl-2 family proteins and possible role of TNF-RS. Clinical and experimental immunology. vol 125. issue 1. 2001-09-06. PMID:11472434. |
however, attempts to induce fas-mediated apoptosis in these high fas expressing cells, as evaluated by propidium iodide staining and apo2.7 staining, were unsuccessful. |
2001-09-06 |
2023-08-12 |
human |
| B Adler, S Ashkar, H Cantor, G F Webe. Costimulation by extracellular matrix proteins determines the response to TCR ligation. Cellular immunology. vol 210. issue 1. 2001-09-06. PMID:11485350. |
engagement of the tcr leads to induction of fas, but not to measurable il-2 secretion or apoptosis. |
2001-09-06 |
2023-08-12 |
Not clear |
| R Maruyama, G Takemura, T Aoyama, K Hayakawa, M Koda, Y Kawase, X Qiu, Y Ohno, S Minatoguchi, K Miyata, T Fujiwara, H Fujiwar. Dynamic process of apoptosis in adult rat cardiomyocytes analyzed using 48-hour videomicroscopy and electron microscopy: beating and rate are associated with the apoptotic process. The American journal of pathology. vol 159. issue 2. 2001-09-06. PMID:11485926. |
soluble fas ligand (0.1 microg/ml) in the presence of actinomycin d (0.05 microg/ml) induced apoptosis in cultured adult rat cardiomyocytes, as documented by activated caspase-3, dna fragmentation, and apoptotic ultrastructure. |
2001-09-06 |
2023-08-12 |
rat |
| S Abe, K Kotoh, S Arao, A Tabaru, M Otsuk. Fas antigen expression on hepatocytes predicts the short- and long-term response to interferon therapy in patients with chronic hepatitis C. Scandinavian journal of gastroenterology. vol 36. issue 3. 2001-08-30. PMID:11305523. |
fas antigen expression on hepatocytes predicts the short- and long-term response to interferon therapy in patients with chronic hepatitis c. interaction between fas antigen on hepatocytes and fas ligand on cytotoxic t cells induces apoptosis, a major mechanism of hepatitis c virus (hcv) -induced hepatocyte injury. |
2001-08-30 |
2023-08-12 |
Not clear |
| M Kunz, S Ibrahim, D Koczan, H J Thiesen, H J Köhler, T Acker, K H Plate, S Ludwig, U R Rapp, E B Bröcker, G N van Muijen, E Flory, G Gros. Activation of c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK) is critical for hypoxia-induced apoptosis of human malignant melanoma. Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research. vol 12. issue 3. 2001-08-30. PMID:11306514. |
in contrast to recent findings, jnk/sapk activation did not correlate with fas or fas ligand (fasl) expression, suggesting that the fas/fasl system is not involved in hypoxia-induced apoptosis in melanoma cells. |
2001-08-30 |
2023-08-12 |
human |
| S Khan, A Koepke, G Jarad, K Schlessman, R P Cleveland, B Wang, M Konieczkowski, J R Schellin. Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney international. vol 60. issue 1. 2001-08-30. PMID:11422737. |
apoptosis and jnk activation are differentially regulated by fas expression level in renal tubular epithelial cells. |
2001-08-30 |
2023-08-12 |
Not clear |
| S Khan, A Koepke, G Jarad, K Schlessman, R P Cleveland, B Wang, M Konieczkowski, J R Schellin. Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney international. vol 60. issue 1. 2001-08-30. PMID:11422737. |
in vitro, cytokine- or hypoxia-induced up-regulation of fas expression is associated with rtc apoptosis. |
2001-08-30 |
2023-08-12 |
Not clear |
| S Khan, A Koepke, G Jarad, K Schlessman, R P Cleveland, B Wang, M Konieczkowski, J R Schellin. Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney international. vol 60. issue 1. 2001-08-30. PMID:11422737. |
in contrast, constitutively expressed, low level rtc fas does not mediate apoptosis, suggesting that fas may be coupled to expression level-dependent rtc signaling pathways. |
2001-08-30 |
2023-08-12 |
Not clear |
| S Khan, A Koepke, G Jarad, K Schlessman, R P Cleveland, B Wang, M Konieczkowski, J R Schellin. Apoptosis and JNK activation are differentially regulated by Fas expression level in renal tubular epithelial cells. Kidney international. vol 60. issue 1. 2001-08-30. PMID:11422737. |
fas is known to signal through jnk in many systems, but the requirement of jnk activation for apoptosis remains controversial. |
2001-08-30 |
2023-08-12 |
Not clear |