| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Suzuki, Y Nakabayashi, R Takahash. Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 15. 2001-08-30. PMID:11447297. |
finally, the ring finger mutants of xiap were less effective than wild-type xiap at preventing apoptosis induced by overexpression of either active-form caspase-3 or fas. |
2001-08-30 |
2023-08-12 |
Not clear |
| V N Ivanov, A Bhoumik, M Krasilnikov, R Raz, L B Owen-Schaub, D Levy, C M Horvath, Z Rona. Cooperation between STAT3 and c-jun suppresses Fas transcription. Molecular cell. vol 7. issue 3. 2001-08-30. PMID:11463377. |
decreased fas expression during tumor progression often results in a loss of fas-ligand (fasl)-mediated apoptosis. |
2001-08-30 |
2023-08-12 |
mouse |
| V N Ivanov, A Bhoumik, M Krasilnikov, R Raz, L B Owen-Schaub, D Levy, C M Horvath, Z Rona. Cooperation between STAT3 and c-jun suppresses Fas transcription. Molecular cell. vol 7. issue 3. 2001-08-30. PMID:11463377. |
the expression of dominant negative stat3 or c-jun in melanoma cells efficiently increased fas expression and sensitized cells to fasl-induced apoptosis. |
2001-08-30 |
2023-08-12 |
mouse |
| V N Ivanov, A Bhoumik, M Krasilnikov, R Raz, L B Owen-Schaub, D Levy, C M Horvath, Z Rona. Cooperation between STAT3 and c-jun suppresses Fas transcription. Molecular cell. vol 7. issue 3. 2001-08-30. PMID:11463377. |
stat3+/- as well as c-jun-/- cells exhibited increased fas cell surface expression and higher sensitivity to fasl-mediated apoptosis. |
2001-08-30 |
2023-08-12 |
mouse |
| M W Bennett, J O'Connell, A Houston, J Kelly, G C O'Sullivan, J K Collins, F Shanaha. Fas ligand upregulation is an early event in colonic carcinogenesis. Journal of clinical pathology. vol 54. issue 8. 2001-08-30. PMID:11477113. |
fas ligand (fasl) is a mediator of apoptosis via the fas receptor (fas/cd95/apo-1). |
2001-08-30 |
2023-08-12 |
Not clear |
| M W Bennett, J O'Connell, A Houston, J Kelly, G C O'Sullivan, J K Collins, F Shanaha. Fas ligand upregulation is an early event in colonic carcinogenesis. Journal of clinical pathology. vol 54. issue 8. 2001-08-30. PMID:11477113. |
normal colonic epithelium expresses fas, and appears to be relatively sensitive to fas mediated apoptosis. |
2001-08-30 |
2023-08-12 |
Not clear |
| M W Bennett, J O'Connell, A Houston, J Kelly, G C O'Sullivan, J K Collins, F Shanaha. Fas ligand upregulation is an early event in colonic carcinogenesis. Journal of clinical pathology. vol 54. issue 8. 2001-08-30. PMID:11477113. |
colonic adenocarcinomas coexpress fasl and fas without undergoing widespread apoptosis. |
2001-08-30 |
2023-08-12 |
Not clear |
| G Dworacki, N Meidenbauer, I Kuss, T K Hoffmann, W Gooding, M Lotze, T L Whitesid. Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 7. issue 3 Suppl. 2001-08-23. PMID:11300496. |
annexin v binding, the loss of fas expression from the cell surface as well as zeta down-regulation, which are associated with early apoptosis, were detected in a proportion of circulating fas+cd3+. |
2001-08-23 |
2023-08-12 |
human |
| G Dworacki, N Meidenbauer, I Kuss, T K Hoffmann, W Gooding, M Lotze, T L Whitesid. Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma. Clinical cancer research : an official journal of the American Association for Cancer Research. vol 7. issue 3 Suppl. 2001-08-23. PMID:11300496. |
in jurkat cells incubated with agonistic anti-fas antibody (ch-11), a rapid loss of fas expression from the cell surface coincided with annexin v binding and preceded the loss of zeta chain during early apoptosis. |
2001-08-23 |
2023-08-12 |
human |
| M Kornacker, M R Verneris, B Kornacker, C Scheffold, R S Negri. Survivin expression correlates with apoptosis resistance after lymphocyte activation and is found preferentially in memory T cells. Immunology letters. vol 76. issue 3. 2001-08-23. PMID:11306144. |
next, we correlated survivin expression with fas, fasl and the amount of apoptosis over time in culture. |
2001-08-23 |
2023-08-12 |
Not clear |
| A Stephanou, T M Scarabelli, B K Brar, Y Nakanishi, M Matsumura, R A Knight, D S Latchma. Induction of apoptosis and Fas receptor/Fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the STAT-1 transcription factor but not tyrosine 701. The Journal of biological chemistry. vol 276. issue 30. 2001-08-23. PMID:11309387. |
induction of apoptosis and fas receptor/fas ligand expression by ischemia/reperfusion in cardiac myocytes requires serine 727 of the stat-1 transcription factor but not tyrosine 701. |
2001-08-23 |
2023-08-12 |
Not clear |
| J Van Der Werff Ten Bosch, J Otten, K Thieleman. Autoimmune lymphoproliferative syndrome type III: an indefinite disorder. Leukemia & lymphoma. vol 41. issue 1-2. 2001-08-23. PMID:11342357. |
although the pathogenesis is not fully understood, deficient fas mediated apoptosis appears to be an important factor. |
2001-08-23 |
2023-08-12 |
Not clear |
| S Kamihira, Y Yamad. Soluble Fas (APO-1/CD95) isoform in adult T-cell leukemia. Leukemia & lymphoma. vol 41. issue 1-2. 2001-08-23. PMID:11342370. |
fas (apo-1/cd95) consists mainly of 2 isoforms, membrane-anchored (mfas) and soluble (sfas), both of which can mediate apoptosis through the fas-signalling process, not only in normal but also in leukemia t-cells. |
2001-08-23 |
2023-08-12 |
Not clear |
| S Kamihira, Y Yamad. Soluble Fas (APO-1/CD95) isoform in adult T-cell leukemia. Leukemia & lymphoma. vol 41. issue 1-2. 2001-08-23. PMID:11342370. |
for studying the tumor biology related to fas-mediated apoptosis, atl cells with up-regulated fas proteins and its mrnas are convenient and useful for understanding apoptotic oncology as it occurs in nature. |
2001-08-23 |
2023-08-12 |
Not clear |
| J O Nwankw. Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. Medical hypotheses. vol 56. issue 5. 2001-08-23. PMID:11388772. |
tumor cells are more vulnerable to this induced toxicity due to possession of specific phenotypes of elevated expression for fas and pyruvate kinase, type m2, both factors inducing tumor cell apoptosis on inhibition. |
2001-08-23 |
2023-08-12 |
Not clear |
| Z Tan, J Levid, S S Schreibe. Increased expression of Fas (CD95/APO-1) in adult rat brain after kainate-induced seizures. Neuroreport. vol 12. issue 9. 2001-08-23. PMID:11435933. |
fas (cd95/apo-1), a transmembrane glycoprotein and receptor for the fas ligand, plays an important role in apoptosis. |
2001-08-23 |
2023-08-12 |
rat |
| Z Tan, J Levid, S S Schreibe. Increased expression of Fas (CD95/APO-1) in adult rat brain after kainate-induced seizures. Neuroreport. vol 12. issue 9. 2001-08-23. PMID:11435933. |
fas induction was correlated with neuronal apoptosis as demonstrated by colocalization of fas and terminal dt-mediated dutp nick end-labeling (tunel). |
2001-08-23 |
2023-08-12 |
rat |
| T Suhara, T Mano, B E Oliveira, K Wals. Phosphatidylinositol 3-kinase/Akt signaling controls endothelial cell sensitivity to Fas-mediated apoptosis via regulation of FLICE-inhibitory protein (FLIP). Circulation research. vol 89. issue 1. 2001-08-23. PMID:11440972. |
fas is constitutively expressed on endothelial cells, but in contrast to smooth muscle and other cell types, endothelial cells are highly resistant to fas-mediated apoptosis. |
2001-08-23 |
2023-08-12 |
Not clear |
| R Roggero, V Robert-Hebmann, S Harrington, J Roland, L Vergne, S Jaleco, C Devaux, M Biard-Piechaczy. Binding of human immunodeficiency virus type 1 gp120 to CXCR4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of Fas signaling. Journal of virology. vol 75. issue 16. 2001-08-23. PMID:11462036. |
binding of human immunodeficiency virus type 1 gp120 to cxcr4 induces mitochondrial transmembrane depolarization and cytochrome c-mediated apoptosis independently of fas signaling. |
2001-08-23 |
2023-08-12 |
human |
| K Maedler, G A Spinas, R Lehmann, P Sergeev, M Weber, A Fontana, N Kaiser, M Y Donat. Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes. vol 50. issue 8. 2001-08-23. PMID:11473025. |
glucose induces beta-cell apoptosis via upregulation of the fas receptor in human islets. |
2001-08-23 |
2023-08-12 |
human |