| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wenjie Su, Min Xie, Yao Li, Xinran Gong, Jiacen L. Topiramate Reverses Physiological and Behavioral Alterations by Postoperative Cognitive Dysfunction in Rat Model Through Inhibiting TNF Signaling Pathway. Neuromolecular medicine. vol 22. issue 2. 2021-07-19. PMID:31758388. |
besides, inhibition of fas enhanced tpm-induced down-regulation of apoptosis of neuronal cell in hippocampus tissues of pocd rats. |
2021-07-19 |
2023-08-13 |
rat |
| Xin Chen, Xiaoshan Yang, Pingyun Yuan, Ronghua Jin, Lili Bao, Xinyu Qiu, Siying Liu, Tao Liu, John Justin Gooding, WanJun Chen, Guozhen Liu, Yongkang Bai, Shiyu Liu, Yan Ji. Modular immune-homeostatic microparticles promote immune tolerance in mouse autoimmune models. Science translational medicine. vol 13. issue 584. 2021-07-12. PMID:33692135. |
specifically, in an experimental model of colitis, ihms rapidly released monocyte chemotactic protein-1 after intravenous administration, which recruited activated t cells and then induced their apoptosis by conjugated fas ligand on the ihm surface. |
2021-07-12 |
2023-08-13 |
mouse |
| Zhaoyi Song, Xinyu Tian, Qingyun Sh. Fas, Caspase-8, and Caspase-9 pathway-mediated bile acid-induced fetal cardiomyocyte apoptosis in intrahepatic cholestasis pregnant rat models. The journal of obstetrics and gynaecology research. vol 47. issue 7. 2021-07-05. PMID:33847039. |
fas, caspase-8, and caspase-9 pathway-mediated bile acid-induced fetal cardiomyocyte apoptosis in intrahepatic cholestasis pregnant rat models. |
2021-07-05 |
2023-08-13 |
rat |
| Zhaoyi Song, Xinyu Tian, Qingyun Sh. Fas, Caspase-8, and Caspase-9 pathway-mediated bile acid-induced fetal cardiomyocyte apoptosis in intrahepatic cholestasis pregnant rat models. The journal of obstetrics and gynaecology research. vol 47. issue 7. 2021-07-05. PMID:33847039. |
in this study, we aimed to investigate the role of fas, caspase-8, and caspase-9 pathways in the internal relations of fetal myocardial apoptosis in icp rat models, thus resulting in fetal intrauterine death. |
2021-07-05 |
2023-08-13 |
rat |
| Wen-Yuan Lin, Bruce Chi-Kang Tsai, Cecilia Hsuan Day, Ping-Ling Chiu, Ray-Jade Chen, Michael Yu-Chih Chen, V Vijaya Padma, Hsiang-Ning Luk, Hsiang-Chen Lee, Chih-Yang Huan. Arecoline induces heart injure via Fas/Fas ligand apoptotic pathway in heart of Sprague-Dawley rat. Environmental toxicology. vol 36. issue 8. 2021-07-05. PMID:33929070. |
arecoline promoted the protein expression of both fas dependent snd mitochondrial dependent apoptosis. |
2021-07-05 |
2023-08-13 |
rat |
| Anhui Yang, Ping Zhang, Zhen Sun, Xin Liu, Xinrui Zhang, Xingkai Liu, Di Wang, Zhaoli Men. Lysionotin induces apoptosis of hepatocellular carcinoma cells via caspase-3 mediated mitochondrial pathway. Chemico-biological interactions. vol 344. 2021-06-25. PMID:33989594. |
additionally, the pre-treatment of ac-devd-cho, an inhibitor of caspase-3, strongly restored the low cell viability, the enhanced apoptosis rate, the dissipation of mmp caused by lysionotin exposure, as well as prevented the lysionotin-caused enhancement on expressions of apoptosis related proteins, especially cleaved poly (adp-ribose) polymerase (parp), fas ligand (fasl), cleaved caspase-3 and bax in both hepg2 and smmc-7721 cells. |
2021-06-25 |
2023-08-13 |
mouse |
| Roxanne Couture, Nathalie Mora, Sheiraz Al Bittar, Mustapha Najih, Mohamed Touaibia, Luc J Marti. Luteolin modulates gene expression related to steroidogenesis, apoptosis, and stress response in rat LC540 tumor Leydig cells. Cell biology and toxicology. vol 36. issue 1. 2021-06-23. PMID:31201582. |
in addition, increased expression of genes such as fas, cdkn1a, atp7b, and tp53, as well as increased accumulation of cleaved caspase 3 and parp, in response to luteolin treatment indicates that apoptosis is being activated. |
2021-06-23 |
2023-08-13 |
rat |
| Hilit Levy-Barazany, Liat Shachnai-Pinkas, Galina Rodionov, Alex Saar, Michal Rosenzwaig, Liron Gez, Anastasia Rodin, Nitzan Marelly, Michal Abraham, Inbal Mishalian, Hila Wildbaum, Tamar Katz, Yuval Baar, Shai Yarkoni, Ronit Bakimer-Kleiner, Amnon Peled, Tsila Zuckerman, Jerry Stei. Brief ex vivo Fas-ligand incubation attenuates GvHD without compromising stem cell graft performance. Bone marrow transplantation. vol 55. issue 7. 2021-06-21. PMID:32433499. |
here we show that a short incubation (2 h) of mpbcs with hexameric fas ligand (fasl) selectively induces apoptosis of specific donor t cell subsets and apcs but not of cd34 |
2021-06-21 |
2023-08-13 |
Not clear |
| F A Monsalve, A Rojas, I Gonzalez, R Perez, C Añasco, J Romero, P Araya, L S Santos, F Delgado-Lope. RID: Evaluation of the Possible Inhibiting Effect of the Proinflammatory Signaling Induced by TNF- Mediators of inflammation. vol 2020. 2021-06-21. PMID:32655311. |
rid downregulates the cell surface expression of epidermal growth factor receptor (egfr), tumor necrosis factor receptor (tnfr), and apoptosis antigen 1 (fas), causing a reduction of the effects of their respective ligands. |
2021-06-21 |
2023-08-13 |
human |
| Xun Yin, Yingjie Wang, Yingfei Sun, Yun Han, Huanling Sun, Mengyun Zou, Ronglong Luo, Xiuli Pen. Down-regulated gga-miR-223 inhibits proliferation and induces apoptosis of MG-infected DF-1 cells by targeting FOXO3. Microbial pathogenesis. vol 155. 2021-06-17. PMID:33932542. |
further studies showed that overexpressed gga-mir-223 could promote cell proliferation, cell cycle, and inhibit cell apoptosis by notably promoting the expression of cell cycle marker genes cyclin-dependent kinase 1 (cdk1), cyclin-dependent kinase 6 (cdk6) and cyclin d1 (ccnd1) and inhibiting the expression of apoptosis markers bcl-2-like 11(bim), fas ligand (faslg) and tnf-related apoptosis-inducing ligand (trail). |
2021-06-17 |
2023-08-13 |
chicken |
| Yu-Lan Yeh, Min-Chi Lu, Bruce Chi-Kang Tsai, Bor-Show Tzang, Shiu-Min Cheng, Xiaoyong Zhang, Liang-Yo Yang, B Mahalakshmi, Wei-Wen Kuo, Peng Xiang, Chih-Yang Huan. Heat-Killed Lactobacillus reuteri GMNL-263 Inhibits Systemic Lupus Erythematosus-Induced Cardiomyopathy in NZB/W F1 Mice. Probiotics and antimicrobial proteins. vol 13. issue 1. 2021-06-16. PMID:32514746. |
significant reduction in tunel-positive cells, fas death receptor-related components, and apoptosis was also detected in the cardiac tissues of the nzb/w f1 mice after l. reuteri gmnl-263 feeding compared with the control group. |
2021-06-16 |
2023-08-13 |
mouse |
| Laurynas Vilys, Inga Peciuliene, Egle Jakubauskiene, Ruta Zinkeviciute, Yuichi Makino, Arvydas Kanopk. U2AF - Hypoxia-induced fas alternative splicing regulator. Experimental cell research. vol 399. issue 1. 2021-06-15. PMID:33347855. |
fas pre-mrna is alternatively spliced by excluding exon 6 to produce soluble fas (sfas) protein that lacks a transmembrane domain and acts by inhibiting fas mediated apoptosis. |
2021-06-15 |
2023-08-13 |
Not clear |
| Sean Hasan, Belal Alshaikh, Kamran Yusu. Serum levels of soluble Fas and Fas ligand in pregnant women who smoke. American journal of reproductive immunology (New York, N.Y. : 1989). vol 85. issue 6. 2021-06-14. PMID:33247994. |
during normal pregnancy, fas ligand (fasl) present on trophoblasts induces apoptosis of fas bearing maternal immune cells. |
2021-06-14 |
2023-08-13 |
Not clear |
| Sofie Mossner, Doreen Manuela Floss, Jürgen Schelle. Pro- and anti-apoptotic fate decisions induced by di- and trimeric synthetic cytokine receptors. iScience. vol 24. issue 5. 2021-06-12. PMID:34113818. |
simultaneous integration of dimeric interleukin (il-)6 receptor gp130 and trimeric fas as synthetic cytokine receptors in one cell enabled binary cell fate decisions, gp130-mediated proliferation or fas-mediated apoptosis. |
2021-06-12 |
2023-08-13 |
Not clear |
| Hanqing Tang, Shitian Zhang, Cenhan Huang, Keming Li, Qiuhua Zhao, Xiaohua L. MiR-448-5p/VEGFA Axis Protects Cardiomyocytes from Hypoxia Through Regulating the FAS/FAS-L Signaling Pathway. International heart journal. vol 62. issue 3. 2021-06-10. PMID:33994507. |
the expressions of apoptosis-related proteins, mir-448-5p, fas, and fas-l were measured using western blotting and quantitative reverse transcription-polymerase chain reaction (qrt-pcr).hypoxia-reduced h9c2 cell viability and promoted apoptosis. |
2021-06-10 |
2023-08-13 |
rat |
| Yu-Xuan Wu, Hsu-Feng Lu, Yen-Hsi Lin, Hui-Yu Chuang, Shih-Chi Su, Yi-Jen Liao, Yuh-Ching Tw. Branched I antigen regulated cell susceptibility against natural killer cytotoxicity through its N-linked glycosylation and overall expression. Glycobiology. vol 31. issue 5. 2021-06-07. PMID:33403394. |
mutations on two fas extracellular n-linkage sites (118 and 136) for glycosylation impaired activation of fas-mediated apoptosis during nk-92mi cytotoxicity. |
2021-06-07 |
2023-08-13 |
Not clear |
| Chengqiang Wang, Hui He, Gen Liu, Haoyue Ma, Li Li, Mingdong Jiang, Qianwei Lu, Pan Li, Hongyi Q. DT-13 induced apoptosis and promoted differentiation of acute myeloid leukemia cells by activating AMPK-KLF2 pathway. Pharmacological research. vol 158. 2021-06-04. PMID:32416217. |
moreover, dt-13 induced the death receptor pathway-dependent apoptosis of hl-60 and kasumi-1 cells by up-regulating fas, fasl, dr5 and trail as well as promoted the cleavage of caspase 8, caspase 3 and parp. |
2021-06-04 |
2023-08-13 |
mouse |
| Haruki Jimbo, Hiroshi Nagai, Susumu Fujiwara, Noriko Shimoura, Chikako Nishigor. Fas-FasL interaction in cytotoxic T cell-mediated vitiligo: The role of lesional expression of tumor necrosis factor-α and interferon-γ in Fas-mediated melanocyte apoptosis. Experimental dermatology. vol 29. issue 1. 2021-06-01. PMID:31675451. |
tumor necrosis factor (tnf)-α and interferon (ifn)-γ, the expression levels of which have been reported to be elevated in lesional skin of patients with vitiligo, synergistically upregulated fas expression on human melanocytes but inhibited the fas-mediated apoptosis. |
2021-06-01 |
2023-08-13 |
mouse |
| Sandro Sacchi, Paola Sena, Chiara Addabbo, Erika Cuttone, Antonio La Marc. Gonadotrophins modulate cell death-related genes expression in human endometrium. Hormone molecular biology and clinical investigation. vol 41. issue 2. 2021-06-01. PMID:32304301. |
fsh induced autophagy and apoptosis by increasing the relative expression of map1lc3b and fas receptor. |
2021-06-01 |
2023-08-13 |
human |
| D V Novikov, S G Selivanova, N V Krasnogorova, E N Gorshkova, S N Pleskova, V V Novikov, A V Karaulo. Serum Protein Corona Abolishes Changes in the Expression of Proinflammatory Genes Induced by Quantum Dots in Human Blood Mononuclear Cell. Bulletin of experimental biology and medicine. vol 169. issue 1. 2021-06-01. PMID:32495165. |
we studied changes in the transcription of genes encoding cytokines (tnf, il-6, il-10, and il-32), cell activation markers (icam1, cd38, fas, and fcgriii), ros production catalyst (nox2), autophagy (beclin 1, lc3b, and p62) and apoptosis (bax, bcl2) regulators in peripheral blood mononuclear cells upon contact with quantum dots cdse/zns-mpa and cdse/cdsezns/zns-ptvp. |
2021-06-01 |
2023-08-13 |
human |