| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patamapan Tamvapee, Ramida Watanapokasi. Apoptosis Induction through MAPK Signaling Pathway in LoVo Cells by Fatty Acid Fraction from Rice Bran Oil. Nutrition and cancer. 2021-08-30. PMID:34459332. |
the results demonstrated that fas inhibited cell viability and induced cell death via apoptosis associated with mapks pathway. |
2021-08-30 |
2023-08-13 |
human |
| Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gon. Fas regulates the apoptosis and migration of trophoblast cells by targeting NF-κB. Experimental and therapeutic medicine. vol 22. issue 4. 2021-08-27. PMID:34434269. |
fas regulates the apoptosis and migration of trophoblast cells by targeting nf-κb. |
2021-08-27 |
2023-08-13 |
human |
| Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gon. Fas regulates the apoptosis and migration of trophoblast cells by targeting NF-κB. Experimental and therapeutic medicine. vol 22. issue 4. 2021-08-27. PMID:34434269. |
the results of flow cytometry, cell counting kit-8 and transwell assays indicated that the overexpression of fas promoted apoptosis, suppressed viability and impaired the migration of the human trophoblast cells. |
2021-08-27 |
2023-08-13 |
human |
| Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gon. Fas regulates the apoptosis and migration of trophoblast cells by targeting NF-κB. Experimental and therapeutic medicine. vol 22. issue 4. 2021-08-27. PMID:34434269. |
by contrast, the knockdown of fas decreased the apoptosis of trophoblast cells and increased their viability and migration. |
2021-08-27 |
2023-08-13 |
human |
| Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gon. Fas regulates the apoptosis and migration of trophoblast cells by targeting NF-κB. Experimental and therapeutic medicine. vol 22. issue 4. 2021-08-27. PMID:34434269. |
notably, the overexpression of nf-κb p65 attenuated the fas knockdown-induced inhibition of apoptosis and acceleration of migration of the trophoblast cells. |
2021-08-27 |
2023-08-13 |
human |
| Ruihong Lan, Yang Yang, Jie Song, Ling Wang, Humin Gon. Fas regulates the apoptosis and migration of trophoblast cells by targeting NF-κB. Experimental and therapeutic medicine. vol 22. issue 4. 2021-08-27. PMID:34434269. |
these results indicate that fas regulates the apoptosis and migration of trophoblast cells by targeting nf-κb, which suggests that the silencing of fas is a promising therapeutic strategy for preeclampsia. |
2021-08-27 |
2023-08-13 |
human |
| Andre G Loxton, Ilana C van Rensbur. FasL regulatory B-cells during Mycobacterium tuberculosis infection and TB disease. Journal of molecular biology. vol 433. issue 13. 2021-08-24. PMID:33845087. |
expression and interaction of the fas receptor-ligand promotes the induction of apoptosis and the induction of t-cell tolerance. |
2021-08-24 |
2023-08-13 |
mouse |
| Ana Patrícia Bastos Ferreira, Ana Paula Pimentel Cassilhas, Patrícia Moura, Pedro Augusto Sampaio Rocha-Filh. Intrinsic and Extrinsic Cell Apoptotic Pathways in Patients with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Systematic Review. Viral immunology. vol 34. issue 6. 2021-08-16. PMID:33470891. |
the descriptors used for this systematic literature review were: tropical paraparesis, proto-oncogenic protein c, bcl-2, bcl-x protein, bax protein, fas ligand (fasl) protein, fas receptor, tnf-related apoptosis-inducing ligand and fas-associated protein with death domain (fadd)-like apoptosis regulating. |
2021-08-16 |
2023-08-13 |
human |
| Ana Patrícia Bastos Ferreira, Ana Paula Pimentel Cassilhas, Patrícia Moura, Pedro Augusto Sampaio Rocha-Filh. Intrinsic and Extrinsic Cell Apoptotic Pathways in Patients with HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Systematic Review. Viral immunology. vol 34. issue 6. 2021-08-16. PMID:33470891. |
increased bcl-xl expression inhibited t lymphocyte apoptosis, whereas bcl-2, serum levels, and cellular expression did not influence t lymphocyte apoptosis and serum levels of fas were significantly higher and associated with markers of leukocyte activation in patients with ham/tsp. |
2021-08-16 |
2023-08-13 |
human |
| Rui Ding, Han Huang, Hongyu Wang, Zewen Yi, Siyu Qiu, Yingjun Lv, Endong Ba. Goose Nephritic Astrovirus Infection of Goslings Induces Lymphocyte Apoptosis, Reticular Fiber Destruction, and CD8 T-Cell Depletion in Spleen Tissue. Viruses. vol 13. issue 6. 2021-08-16. PMID:34207913. |
furthermore, tunel staining confirmed apoptosis of lymphocytes, and the mrna levels of fas and fasl were significantly increased in the gnastv-infected goslings. |
2021-08-16 |
2023-08-13 |
Not clear |
| Joyshikh Sonowal, Chhabi Lal Patel, Ravi Kumar Gandham, Basavaraj Sajjanar, Raja Ishaq Nabi Khan, Manas Ranjan Praharaj, Waseem Akram Malla, Deepak Kumar, Kapil Dev, N Barkathullah, Krishna Bharali, Amitesh Dubey, D Lalita, Insha Zafir, B P Mishra, Bina Mishr. Genome-wide expression analysis reveal host genes involved in immediate-early infections of different sheeppox virus strains. Gene. vol 801. 2021-08-16. PMID:34274484. |
sppv modulates the expression of several important host proteins such as cd40, fas, itgβ1, itgα1, pak1, pak2, cd14, ilk leading to viral attachment and entry; immune-related degs such as mapk, jnk, erk, nfkb, ikb, pi3k, stat which provide optimal cellular condition for early viral protein expression; and foxo3, atf, cdkna1, tcf, srf, bdnf which help in inducing apoptosis and mptp, bad and tp53 inhibits apoptosis or cell death at the immediate-early time. |
2021-08-16 |
2023-08-13 |
Not clear |
| Paola Ayala-Ramírez, Catalina Machuca-Acevedo, Tatiana Gámez, Sandra Quijano, Alfonso Barreto, Jaime L Silva, Mercedes Olaya-C, Reggie García-Roble. Assessment of Placental Extracellular Vesicles-Associated Fas Ligand and TNF-Related Apoptosis-Inducing Ligand in Pregnancies Complicated by Early and Late Onset Preeclampsia. Frontiers in physiology. vol 12. 2021-08-10. PMID:34366896. |
it has also been reported that placenta-derived extracellular vesicles (ev) carry fas ligand (fasl) and tumor necrosis factor-related apoptosis-inducing ligand (trail) and trigger apoptosis in jurkat t cells. |
2021-08-10 |
2023-08-13 |
Not clear |
| Lin Bai, Yongtao Lin, Juan Xie, Yiyuan Zhang, Hongwu Wang, Donghui Zhen. MiR-27b-3p inhibits the progression of renal fibrosis via suppressing STAT1. Human cell. vol 34. issue 2. 2021-08-06. PMID:33454903. |
in addition, overexpression of mir-27b-3p markedly decreased tgf-β1-induced apoptosis in hk-2 cells, as evidenced by the decreased levels of fas, active caspase 8 and active caspase 3. |
2021-08-06 |
2023-08-13 |
mouse |
| Yoshiaki Sato, Hironori Yoshino, Eichi Tsuruga, Ikuo Kashiwakur. Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-like Receptor Agonist and Radiation. Current cancer drug targets. vol 20. issue 5. 2021-08-02. PMID:31951181. |
fas ligand enhances apoptosis of human lung cancer cells cotreated with rig-i-like receptor agonist and radiation. |
2021-08-02 |
2023-08-13 |
human |
| Yoshiaki Sato, Hironori Yoshino, Eichi Tsuruga, Ikuo Kashiwakur. Fas Ligand Enhances Apoptosis of Human Lung Cancer Cells Cotreated with RIG-I-like Receptor Agonist and Radiation. Current cancer drug targets. vol 20. issue 5. 2021-08-02. PMID:31951181. |
in addition, cotreatment with poly(i:c)-hmw and ir induced apoptosis in a fas-independent manner, and increased fas expression on the cell surface. |
2021-08-02 |
2023-08-13 |
human |
| J Rzemieniec, E Bratek, A Wnuk, K Przepiórska, E Salińska, M Kajt. Neuroprotective effect of 3,3'-Diindolylmethane against perinatal asphyxia involves inhibition of the AhR and NMDA signaling and hypermethylation of specific genes. Apoptosis : an international journal on programmed cell death. vol 25. issue 9-10. 2021-07-30. PMID:32816128. |
in addition, dim inhibited apoptosis and oxidative stress accompanying perinatal asphyxia through: downregulation of fas, casp-3, capn1, gpx3 and sod-1, attenuation of caspase-9 activity, and upregulation of anti-apoptotic bcl2 mrna. |
2021-07-30 |
2023-08-13 |
human |
| Kiarash Saleki, Mohammad Banazadeh, Niloufar Sadat Miri, Abbas Azadmeh. Triangle of cytokine storm, central nervous system involvement, and viral infection in COVID-19: the role of sFasL and neuropilin-1. Reviews in the neurosciences. 2021-07-27. PMID:34225390. |
apoptosis of cells invaded by this virus involves fas receptor-fas ligand (fasl) signaling; moreover, fas receptor may function as a controller of inflammation. |
2021-07-27 |
2023-08-13 |
Not clear |
| Takamichi Ojima, Masashi Kawami, Ryoko Yumoto, Mikihisa Takan. Differential mechanisms underlying methotrexate-induced cell death and epithelial-mesenchymal transition in A549 cells. Toxicological research. vol 37. issue 3. 2021-07-24. PMID:34295794. |
furthermore, the increase in the mrna expression of α-sma was well correlated with cyclin-dependent kinase inhibitor 1a, a cell cycle arrest marker, but not with bcl-2 binding component 3 and fas cell surface death receptor, which are both pro-apoptotic factors, indicating that the mtx-induced emt may be related to cell cycle arrest, but not to apoptosis. |
2021-07-24 |
2023-08-13 |
human |
| b' Jan \\xc5\\xa0r\\xc3\\xa1mek, Vlasta N\\xc4\\x9bmcov\\xc3\\xa1, Jan Kov\\xc3\\xa1\\xc5\\x9. Calcium channel blockers do not protect against saturated fatty acid-induced ER stress and apoptosis in human pancreatic \\xce\\xb2-cells. Nutrition & metabolism. vol 18. issue 1. 2021-07-22. PMID:34274001.' |
it was evidenced that saturated fatty acids (fas) have a detrimental effect on pancreatic β-cells function and survival, leading to endoplasmic reticulum (er) calcium release, er stress, and apoptosis. |
2021-07-22 |
2023-08-13 |
human |
| Zun-Wen Lin, Wei Zhang, Si-Ding Jiang, Wen-Bo Wei, Xiao-Feng L. Inhibition of microRNA-940 suppresses the migration and invasion of human osteosarcoma cells through the secreted frizzled-related protein 1-mediated Wnt/β-catenin signaling pathway. Journal of cellular biochemistry. 2021-07-21. PMID:30324663. |
with the treatment of mir-940 mimic, licl, or sirna-sfrp1, os cells showed promoted proliferation, migration, invasion, tumor formation, and impeded apoptosis (further reflected by elevated bcl-2 expression and reduced fas and bax expression). |
2021-07-21 |
2023-08-13 |
mouse |