| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michał M Hryciuk, Katarina Jewgenow, Beate C Brau. Cloprostenol, a synthetic analog of prostaglandin F2α induces functional regression in cultured luteal cells of felids†. Biology of reproduction. vol 105. issue 1. 2021-11-17. PMID:33864060. |
gene-expression analysis by real-time pcr revealed that treatment with cloprostenol did not have an influence on expression of selected genes coding for enzymes of steroidogenesis (star, hsd3b, cyp11a1) or prostaglandin synthesis (ptgs2, pges), nor did it effect hormone receptors (ar, esr1, pgr, ptger2), an anti-oxidative enzyme (sod1) or factors of cell apoptosis (fas, casp3, tnfrsf1b, bcl2) over the studied period. |
2021-11-17 |
2023-08-13 |
cat |
| Taojie Zhang, Wang-Dui BaSang, Weihua Chang, Shengdong Huo, Xingbin Ma, Xianghong Ju, Sijiu Yu, Sheng Cu. Dynamics of apoptosis-related gene expression during follicular development in yak. Journal of animal physiology and animal nutrition. vol 105. issue 6. 2021-11-12. PMID:33899975. |
p53, caspase-9 (casp9), bax, bcl-2 and fas play a crucial role in the ovarian mitochondrion-dependent apoptosis and death receptor pathway. |
2021-11-12 |
2023-08-13 |
Not clear |
| Taojie Zhang, Wang-Dui BaSang, Weihua Chang, Shengdong Huo, Xingbin Ma, Xianghong Ju, Sijiu Yu, Sheng Cu. Dynamics of apoptosis-related gene expression during follicular development in yak. Journal of animal physiology and animal nutrition. vol 105. issue 6. 2021-11-12. PMID:33899975. |
overall, p53 and fas play an essential role in inducing gc apoptosis, and bax, bcl-2, casp9 and p53 are involved in oviduct epithelial regeneration in yak. |
2021-11-12 |
2023-08-13 |
Not clear |
| Miaomiao Chai, Mingli Jiang, Ce Gu, Qiaohui Lu, Yi Zhou, Ziyang Jin, Yan Zhou, Wensong Ta. Osteogenically differentiated mesenchymal stem cells promote the apoptosis of human umbilical vein endothelial cells in vitro. Biotechnology and applied biochemistry. 2021-11-12. PMID:34694656. |
based on further experiments, pedf mediated the apoptosis and proliferation of huvecs through p53, bax/bcl-2, fas, and c-caspase-3. |
2021-11-12 |
2023-08-13 |
human |
| Xiang Cheng, Feng Geng, Meixia Pan, Xiaoning Wu, Yaogang Zhong, Chunyan Wang, Zhihua Tian, Chunming Cheng, Rui Zhang, Vinay Puduvalli, Craig Horbinski, Xiaokui Mo, Xianlin Han, Arnab Chakravarti, Deliang Gu. Targeting DGAT1 Ameliorates Glioblastoma by Increasing Fat Catabolism and Oxidative Stress. Cell metabolism. vol 32. issue 2. 2021-11-09. PMID:32559414. |
inhibiting dgat1 disrupted lipid homeostasis and resulted in excessive fas moving into mitochondria for oxidation, leading to the generation of high levels of reactive oxygen species (ros), mitochondrial damage, cytochrome c release, and apoptosis. |
2021-11-09 |
2023-08-13 |
Not clear |
| Aziati Azwari Annuar, Ravindran Ankathil, Nazihah Mohd Yunus, Azlan Husin, Nur Shafawati Ab Rajab, Ahmad Aizat Abdul Aziz, Mohd Ismail Ibrahim, Sarina Sulon. Impact of Fas/Fasl Gene Polymorphisms on Susceptibility Risk and Imatinib Mesylate Treatment Response in Chronic Myeloid Leukaemia Patients. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue 2. 2021-11-08. PMID:33639675. |
the fas mediated apoptosis pathway involving the fas and fasl genes plays a crucial role in the regulation of apoptotic cell death and imatinib mesylate (im) mechanism of action. |
2021-11-08 |
2023-08-13 |
Not clear |
| Xin Liang, Jianxin J. Matrine inhibits ovarian cancer cell viability and promotes apoptosis by regulating the ERK/JNK signaling pathway via p38MAPK. Oncology reports. vol 45. issue 5. 2021-11-08. PMID:33786627. |
the results demonstrated that compared with the control group, matrine significantly induced ovarian cancer cell apoptosis by upregulating caspase‑8 and fas cell surface death receptor (fas) expression levels, and downregulating bcl‑2 and bcl‑xl expression levels. |
2021-11-08 |
2023-08-13 |
mouse |
| Meredith Gregory-Ksander, Ann Marshak-Rothstei. The FasLane to ocular pathology-metalloproteinase cleavage of membrane-bound FasL determines FasL function. Journal of leukocyte biology. vol 110. issue 5. 2021-11-05. PMID:33565149. |
both mfasl and sfasl can form trimers that engage the trimeric fas receptor, but only mfasl can form a multimeric complex in lipid rafts to trigger apoptosis and inflammation. |
2021-11-05 |
2023-08-13 |
Not clear |
| Ying-Qi Zhao, Ren-Ren Chen, Qiao-Qiao Kong, Jin-Song An, Xin-Yue Zhao, Shuai Gong, Hong-Jie Yuan, Jing-He Ta. Corticosterone induced apoptosis of mouse oviduct epithelial cells independent of the TNF-α system. The Journal of reproduction and development. vol 67. issue 1. 2021-10-29. PMID:33310974. |
it has been reported in recent studies that restraint stress on pregnant mice during the preimplantation stage elevated corticotrophin-releasing hormone (crh) and glucocorticoid levels in the serum and oviducts; furthermore, crh and corticosterone (cort) impacted preimplantation embryos indirectly by triggering the apoptosis of oviductal epithelial cells (oecs) through activation of the fas system. |
2021-10-29 |
2023-08-13 |
mouse |
| Ying-Qi Zhao, Ren-Ren Chen, Qiao-Qiao Kong, Jin-Song An, Xin-Yue Zhao, Shuai Gong, Hong-Jie Yuan, Jing-He Ta. Corticosterone induced apoptosis of mouse oviduct epithelial cells independent of the TNF-α system. The Journal of reproduction and development. vol 67. issue 1. 2021-10-29. PMID:33310974. |
taken together, our results demonstrated that crh-induced oec apoptosis involved both fas signaling and tnf-α signaling. |
2021-10-29 |
2023-08-13 |
mouse |
| Ying-Qi Zhao, Ren-Ren Chen, Qiao-Qiao Kong, Jin-Song An, Xin-Yue Zhao, Shuai Gong, Hong-Jie Yuan, Jing-He Ta. Corticosterone induced apoptosis of mouse oviduct epithelial cells independent of the TNF-α system. The Journal of reproduction and development. vol 67. issue 1. 2021-10-29. PMID:33310974. |
conversely, cort-induced oec apoptosis involved only the fas, but not the tnf-α, signaling pathway. |
2021-10-29 |
2023-08-13 |
mouse |
| Anna Sirés, Mireia Turch-Anguera, Patricia Bogdanov, Joel Sampedro, Hugo Ramos, Agustín Ruíz Lasa, Jianxin Huo, Shengli Xu, Kong-Peng Lam, Joaquín López-Soriano, M Jose Pérez-García, Cristina Hernández, Rafael Simó, Montse Solé, Joan X Comell. Faim knockout leads to gliosis and late-onset neurodegeneration of photoreceptors in the mouse retina. Journal of neuroscience research. 2021-10-29. PMID:34713467. |
fas apoptotic inhibitory molecule protein (faim) is a death receptor antagonist and an apoptosis regulator. |
2021-10-29 |
2023-08-13 |
mouse |
| Karol Alí Apaza Alccayhuaman, Patrick Heimel, Jung-Seok Lee, Stefan Tangl, Franz J Strauss, Alexandra Stähli, Eva Matalová, Reinhard Grube. FasL Is Required for Osseous Healing in Extraction Sockets in Mice. Frontiers in immunology. vol 12. 2021-10-26. PMID:34135904. |
fas ligand (fasl) is a member of the tumor necrosis factor (tnf) superfamily involved in the activation of apoptosis. |
2021-10-26 |
2023-08-13 |
mouse |
| Evgenia Olegovna Khalturina, Natalia Dmitrievna Degtyareva, Anastasiia Vasi'evna Bairashevskaia, Alena Valerievna Mulenkova, Anna Vladimirovna Degtyarev. Modern diagnostic capabilities of neonatal screening for primary immunodeficiencies in newborns. Clinical and experimental pediatrics. vol 64. issue 10. 2021-10-22. PMID:33781055. |
primary immunodeficiency diseases and primary immunodeficiency syndrome (pids) are a heterogeneous group of diseases and conditions based on impaired immune system function associated with developmental defects and characterized by various combinations of recurrent infections, development of autoimmune and lymphoproliferative syndromes (genetic defects in apoptosis, gene mutation fas receptor or ligand), granulomatous process, and malignant neoplasms. |
2021-10-22 |
2023-08-13 |
Not clear |
| Masumeh Sanaei, Fraidoon Kavoos. Effects of trichostatin A on the intrinsic and extrinsic apoptotic pathway, cell viability, and apoptosis induction in hepatocellular carcinoma cell lines. Gastroenterology and hepatology from bed to bench. vol 14. issue 4. 2021-10-22. PMID:34659660. |
the current study investigated the effect of trichostatin a (tsa) on mitochondrial/intrinsic [pro- (bax, bak, and bim) and anti- (bcl-2, bcl-xl, and mcl-1) apoptotic genes] and cytoplasmic/extrinsic (dr4, dr5, fas, fas-l, and trail genes) pathways, histone deacetylase 1, 2, and 3, p53, p73, cell viability, and apoptosis in hepatocellular carcinoma (hcc) hcclm3, mhcc97h, and mhcc97l cell lines. |
2021-10-22 |
2023-08-13 |
Not clear |
| Y J Park, S Lee, T J Kieffer, G L Warnock, N Safikhan, M Speck, Z Hao, M Woo, L Marzba. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. 2021-10-21. PMID:22301943. |
beta cell fas upregulation, caspase-3 activation, apoptosis and function, and islet il-1β levels were assessed. |
2021-10-21 |
2023-08-12 |
mouse |
| Y J Park, S Lee, T J Kieffer, G L Warnock, N Safikhan, M Speck, Z Hao, M Woo, L Marzba. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. 2021-10-21. PMID:22301943. |
results: hiapp treatment induced fas upregulation, caspase-3 activation and apoptosis in ins-1 and islet cells. |
2021-10-21 |
2023-08-12 |
mouse |
| Y J Park, S Lee, T J Kieffer, G L Warnock, N Safikhan, M Speck, Z Hao, M Woo, L Marzba. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. 2021-10-21. PMID:22301943. |
the amyloid inhibitor or fas antagonist reduced apoptosis in hiapp-treated beta cells. |
2021-10-21 |
2023-08-12 |
mouse |
| Y J Park, S Lee, T J Kieffer, G L Warnock, N Safikhan, M Speck, Z Hao, M Woo, L Marzba. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. 2021-10-21. PMID:22301943. |
islet cells with fas deletion had lower hiapp-induced beta cell apoptosis than those expressing fas. |
2021-10-21 |
2023-08-12 |
mouse |
| Y J Park, S Lee, T J Kieffer, G L Warnock, N Safikhan, M Speck, Z Hao, M Woo, L Marzba. Deletion of Fas protects islet beta cells from cytotoxic effects of human islet amyloid polypeptide. Diabetologia. 2021-10-21. PMID:22301943. |
cultured hiapp-expressing mouse islets with fas deletion had similar amyloid levels, but lower caspase-3 activation and beta cell apoptosis, and a higher islet beta:alpha cell ratio and insulin response to glucose, compared with islets expressing fas and hiapp. |
2021-10-21 |
2023-08-12 |
mouse |