| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wulan Koagouw, Richard J Hazell, Corina Cioca. Induction of apoptosis in the gonads of Mytilus edulis by metformin and increased temperature, via regulation of HSP70, CASP8, BCL2 and FAS. Marine pollution bulletin. vol 173. issue Pt A. 2021-12-06. PMID:34649205. |
induction of apoptosis in the gonads of mytilus edulis by metformin and increased temperature, via regulation of hsp70, casp8, bcl2 and fas. |
2021-12-06 |
2023-08-13 |
Not clear |
| A Wnuk, K Przepiórska, B A Pietrzak, M Kajt. Posttreatment Strategy Against Hypoxia and Ischemia Based on Selective Targeting of Nonnuclear Estrogen Receptors with PaPE-1. Neurotoxicity research. vol 39. issue 6. 2021-12-04. PMID:34797527. |
the mechanisms of the neuroprotective action of pape-1 also involved apoptosis inhibition demonstrated by normalization of both mitochondrial membrane potential and expression levels of apoptosis-related genes and proteins such as fas, fasl, bcl2, fas, fasl, bcl2, bax, and gsk3β. |
2021-12-04 |
2023-08-13 |
mouse |
| Xiang He, Lei Zhang, Lingjuan Hu, Shengbin Liu, Anying Xiong, Junyi Wang, Ying Xiong, Guoping L. PM2.5 Aggravated OVA-Induced Epithelial Tight Junction Disruption Through Fas Associated via Death Domain-Dependent Apoptosis in Asthmatic Mice. Journal of asthma and allergy. vol 14. 2021-12-03. PMID:34848976. |
pm2.5 aggravated ova-induced epithelial tight junction disruption through fas associated via death domain-dependent apoptosis in asthmatic mice. |
2021-12-03 |
2023-08-13 |
mouse |
| Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Ga. Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells. Experimental and therapeutic medicine. vol 23. issue 1. 2021-12-03. PMID:34849158. |
flow cytometry and western blot analysis were used to detect the effects of fas on cell apoptosis and to determine the expression levels of autophagy-related proteins, lc3b and beclin 1, induced by neo. |
2021-12-03 |
2023-08-13 |
Not clear |
| Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Ga. Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells. Experimental and therapeutic medicine. vol 23. issue 1. 2021-12-03. PMID:34849158. |
fas was found to inhibit neo-induced mitochondrial autophagy and mitochondrial membrane potential decline, in addition to reducing ros levels and cell apoptosis caused by neo treatment. |
2021-12-03 |
2023-08-13 |
Not clear |
| Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Ga. Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells. Experimental and therapeutic medicine. vol 23. issue 1. 2021-12-03. PMID:34849158. |
fas and mir-489 mimic inhibited the neo-induced mitochondrial autophagy and mitochondrial membrane potential decline, in addition to reducing ros levels and cell apoptosis. |
2021-12-03 |
2023-08-13 |
Not clear |
| Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Ga. Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells. Experimental and therapeutic medicine. vol 23. issue 1. 2021-12-03. PMID:34849158. |
knockdown of mir-489 expression using a mir-489 inhibitor blocked the inhibitory effects of fas on the mitochondrial membrane potential, cell apoptosis and ros production. |
2021-12-03 |
2023-08-13 |
Not clear |
| Hongseok Yoo, Jin Young Lee, Junseon Park, Gee Young Suh, Kyeongman Jeo. Association of Plasma Levels of Fas Ligand with Severity and Outcome of Sepsis. Shock (Augusta, Ga.). vol 56. issue 4. 2021-12-02. PMID:33577245. |
levels of the apoptosis regulator fas ligand (fasl) are associated with severity of sepsis, but its association with the mortality of sepsis and necroptosis, a regulated cell death mechanism, is not yet clear. |
2021-12-02 |
2023-08-13 |
Not clear |
| Yan Zhang, Linchao Zhang, Jialu Bao, Liantao Liu, Xiaodan Wan. Perfluorooctanoic acid exposure in early pregnancy induces oxidative stress in mice uterus and liver. Environmental science and pollution research international. vol 28. issue 46. 2021-12-02. PMID:34331232. |
we also determined the expressions of fas, fasl, bax, bcl-2, and caspase-3 in decidual cells by immunohistochemistry and the tunel assay to detect apoptosis uterine cells. |
2021-12-02 |
2023-08-13 |
mouse |
| Pengcheng Wang, Wenze Xun, Tianyu Han, Zhujun Chen. FAIM-S functions as a negative regulator of NF-κB pathway and blocks cell cycle progression in NSCLC cells. Cell cycle (Georgetown, Tex.). vol 19. issue 24. 2021-11-30. PMID:33249986. |
in our study, we found that the short form of fas apoptosis inhibitory molecule 1 (faim-s) could regulate the expression of ccnd1 and had a tumor-suppressing role in non-small cell lung cancer (nsclc). |
2021-11-30 |
2023-08-13 |
Not clear |
| Barbora Kalousková, Ondřej Skořepa, Denis Cmunt, Celeste Abreu, Kateřina Krejčová, Jan Bláha, Irena Sieglová, Vlastimil Král, Milan Fábry, Robert Pola, Michal Pechar, Ondřej Vaně. Tumor Marker B7-H6 Bound to the Coiled Coil Peptide-Polymer Conjugate Enables Targeted Therapy by Activating Human Natural Killer Cells. Biomedicines. vol 9. issue 11. 2021-11-30. PMID:34829829. |
the binding of b7-h6 to nkp30 activates nk cells and results in fas ligand or granzyme-mediated apoptosis of target tumor cells. |
2021-11-30 |
2023-08-13 |
human |
| Shaobin Huang, Jing Liao, Xiaohua Luo, Fang Liu, Ge Shi, Weiping We. Kindlin-2 promoted the progression of keloids through the Smad pathway and Fas/FasL pathway. Experimental cell research. vol 408. issue 1. 2021-11-29. PMID:34492266. |
moreover, knocking down kindlin-2 increased the expression of fas and fasl in kfs, which demonstrated that knocking down kindlin-2 promoted the activation of the exogenous apoptotic pathway of kfs and then facilitated apoptosis. |
2021-11-29 |
2023-08-13 |
Not clear |
| Andressa da Silva Castro, Mariana Bodini Angeloni, Bellisa de Freitas Barbosa, Renata Lima de Miranda, Samuel Cota Teixeira, Pâmela Mendonça Guirelli, Fernanda Chaves de Oliveira, Rafaela José da Silva, Priscila Silva Franco, Mayara Ribeiro, Iliana Claudia Balga Milian, Angélica de Oliveira Gomes, Francesca Ietta, Sílvio Favoreto Júnior, Tiago Wilson Patriarca Mineo, José Roberto Mineo, Celene Maria de Oliveira Simões Alves, Eloisa Amália Vieira Ferr. BEWO trophoblast cells and Toxoplasma gondii infection modulate cell death mechanisms in THP-1 monocyte cells by interference in the expression of death receptor and intracellular proteins. Tissue & cell. vol 73. 2021-11-29. PMID:34597888. |
the supernatants were collected and analyzed for the secretion of human fas ligand, and cells were used to determine cell death and apoptosis, cell death receptor, and intracellular proteins expression. |
2021-11-29 |
2023-08-13 |
human |
| Guven Yenmis, Tugba Soydas, Cumhur Gokhan Ekmekci, Ayse Canan Yazici Guvercin, Ozlem Su Kucuk, Gonul Kanigur Sultuybe. Fas and microRNAs Variations as a Possible Risk for Behçet Disease. Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases. vol 27. issue 8. 2021-11-25. PMID:32000230. |
fas and some mirnas have revealed to display remarkable roles in both autoimmune and autoinflammatory processes, and they can play important roles in defective apoptosis in bd. |
2021-11-25 |
2023-08-13 |
Not clear |
| Bao-Li Fei, Chun-Nuan Hui, Zuzhuang Wei, Ling-Yan Kong, Jian-Ying Long, Chunhua Qiao, Zhen-Feng Che. Copper(II) and iron(III) complexes of chiral dehydroabietic acid derived from natural rosin: metal effect on structure and cytotoxicity. Metallomics : integrated biometal science. vol 13. issue 4. 2021-11-23. PMID:33765148. |
caspase-8/caspase-4 activation and up-regulated fas expression indicate that death receptor-mediated extrinsic apoptosis was included. |
2021-11-23 |
2023-08-13 |
Not clear |
| Layanna Freitas de Oliveira, Amanda Araújo Serrão de Andrade, Carla Pagliari, Leda Viegas de Carvalho, Taiana S Silveira, Jedson Ferreira Cardoso, André Luiz Teles E Silva, Janaina Mota de Vasconcelos, Caroline Aquino Moreira-Nunes, Rommel Mario Rodríguez Burbano, Márcio Roberto Teixeira Nunes, Eduardo José Melo Dos Santos, João Lídio da Silva Gonçalves Vianez Júnio. Differential expression analysis and profiling of hepatic miRNA and isomiRNA in dengue hemorrhagic fever. Scientific reports. vol 11. issue 1. 2021-11-22. PMID:33692368. |
enrichment analysis with predicted target genes of micrornas revealed regulatory pathways of apoptosis, involving mapk, ras, cdk and fas. |
2021-11-22 |
2023-08-13 |
human |
| E A Klimentova, I A Suchkov, A A Egorov, R E Kalini. Apoptosis and Cell Proliferation Markers in Inflammatory-Fibroproliferative Diseases of the Vessel Wall (Review). Sovremennye tekhnologii v meditsine. vol 12. issue 4. 2021-11-20. PMID:34795999. |
the main markers of apoptosis (fas, fas ligand, p53, bcl-2, bax) and cell proliferation (toll receptor) have been considered in the current review. |
2021-11-20 |
2023-08-13 |
rabbit |
| Hyun-Ju Kim, Young-Jin Kim, Wansu Par. Berberine modulates hyper-inflammation in mouse macrophages stimulated with polyinosinic-polycytidylic acid via calcium-CHOP/STAT pathway. Scientific reports. vol 11. issue 1. 2021-11-19. PMID:34050236. |
levels of nitric oxide (no), prostaglandin e2 (pge2), first apoptosis signal receptor (fas; cd95), cytokines, intracellular calcium, phosphorylated i-kappa-b-alpha (ikb-α), phosphorylated p38 mitogen-activated protein kinase (mapk), phosphorylated erk1/2, phosphorylated signal transducer and activated transcription 3 (stat3), and mrna expression of inflammatory genes in poly i:c-induced raw 264.7 mouse macrophages were evaluated. |
2021-11-19 |
2023-08-13 |
mouse |
| Edyta Rytelewska, Marta Kiezun, Ewa Zaobidna, Marlena Gudelska, Katarzyna Kisielewska, Kamil Dobrzyn, Tadeusz Kaminski, Nina Smolinsk. Chemerin as a modulator of angiogenesis and apoptosis processes in the corpus luteum of pigs: an in vitro study†. Biology of reproduction. vol 105. issue 4. 2021-11-18. PMID:34192738. |
the study also revealed that chemerin exerts a modulatory effect (stimulatory/inhibitory, depending on the phase of the cycle) on the protein abundance of first apoptosis signal (fas), fas ligand, b-cell lymphoma 2, and caspase-3 in porcine lc. |
2021-11-18 |
2023-08-13 |
Not clear |
| Jin-Woo Kim, Hyun-Ju An, HyunJeong Yeo, Yunhui Jeong, HyeonHae Lee, Jusung Lee, Kisik Nam, Jongheon Lee, Dong-Eun Shin, Soonchul Le. Activation of Hypoxia-Inducible Factor-1α Signaling Pathway Has the Protective Effect of Intervertebral Disc Degeneration. International journal of molecular sciences. vol 22. issue 21. 2021-11-18. PMID:34768786. |
moreover, ca hif-1α reduced the apoptosis of np cells induced by the fas ligand. |
2021-11-18 |
2023-08-13 |
rat |