| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Esperanza Bas, Chhavi Gupta, Thomas R Van De Wate. A novel organ of corti explant model for the study of cochlear implantation trauma. Anatomical record (Hoboken, N.J. : 2007). vol 295. issue 11. 2013-04-04. PMID:23044812. |
hc apoptosis and intracochlear fibrosis are thought to be causes of poor ci functional outcomes. |
2013-04-04 |
2023-08-12 |
rat |
| Maria Chomova, Zuzana Tatarkova, Dusan Dobrota, Peter Raca. Ischemia-induced inhibition of mitochondrial complex I in rat brain: effect of permeabilization method and electron acceptor. Neurochemical research. vol 37. issue 5. 2012-08-20. PMID:22219133. |
add to this, initialization of p53 mitochondrial apoptosis through p53, bax, bcl-x(l) proteins and a possible involvement of grim-19, the ci structural subunit, in apoptotic processes were also studied. |
2012-08-20 |
2023-08-12 |
rat |
| Linda Ebermann, Sylwia Wika, Inga Klumpe, Elke Hammer, Karin Klingel, Dirk Lassner, Uwe Völker, Ulrike Erben, Heinz Zeichhardt, Heinz-Peter Schultheiss, Andrea Dörne. The mitochondrial respiratory chain has a critical role in the antiviral process in Coxsackievirus B3-induced myocarditis. Laboratory investigation; a journal of technical methods and pathology. vol 92. issue 1. 2012-02-15. PMID:21968812. |
correlation analyses including data from the two mouse strains revealed that reduced cvb3 titer correlated with increased ci and ciii activity, oxidative stress as well as active apoptosis during acute myocarditis (mc). |
2012-02-15 |
2023-08-12 |
mouse |
| Alkesh Jani, Elaine Epperson, Jessica Martin, Arijana Pacic, Danica Ljubanovic, Sandra L Martin, Charles L Edelstei. Renal protection from prolonged cold ischemia and warm reperfusion in hibernating squirrels. Transplantation. vol 92. issue 11. 2012-02-02. PMID:22082817. |
we have previously shown that cold ischemia (ci) results in massive increases in caspase-3 activity, tubular apoptosis, and brush border injury (bbi) in mouse kidneys. |
2012-02-02 |
2023-08-12 |
mouse |
| Alkesh Jani, Elaine Epperson, Jessica Martin, Arijana Pacic, Danica Ljubanovic, Sandra L Martin, Charles L Edelstei. Renal protection from prolonged cold ischemia and warm reperfusion in hibernating squirrels. Transplantation. vol 92. issue 11. 2012-02-02. PMID:22082817. |
we sought to determine whether ci and wi during hibernation caused caspase-3 activation, tubular apoptosis, acute tubular necrosis, or bbi, and reduced renal function. |
2012-02-02 |
2023-08-12 |
mouse |
| Dongmei Li, Hui Chen, Abigail Florentino, Deepu Alex, Patricia Sikorski, William A Fonzi, Richard Calderon. Enzymatic dysfunction of mitochondrial complex I of the Candida albicans goa1 mutant is associated with increased reactive oxidants and cell death. Eukaryotic cell. vol 10. issue 5. 2011-10-31. PMID:21398508. |
the consequence of a defective ci in goa31 is an increase in reactive oxidant species (ros), loss of chronological aging, and programmed cell death ([pcd] apoptosis) in vitro compared to control strains. |
2011-10-31 |
2023-08-12 |
human |
| Dongmei Li, Hui Chen, Abigail Florentino, Deepu Alex, Patricia Sikorski, William A Fonzi, Richard Calderon. Enzymatic dysfunction of mitochondrial complex I of the Candida albicans goa1 mutant is associated with increased reactive oxidants and cell death. Eukaryotic cell. vol 10. issue 5. 2011-10-31. PMID:21398508. |
our observation of increased ros production associated with a defective ci and pcd is reminiscent of mitochondrial studies of patients with some types of neurodegenerative diseases where ci and/or ciii dysfunctions lead to increased ros and apoptosis. |
2011-10-31 |
2023-08-12 |
human |
| Kultigin Turkmen, Jessica Martin, Ali Akcay, Quocan Nguyen, Kameswaran Ravichandran, Sarah Faubel, Arijana Pacic, Danica Ljubanović, Charles L Edelstein, Alkesh Jan. Apoptosis and autophagy in cold preservation ischemia. Transplantation. vol 91. issue 11. 2011-07-26. PMID:21577181. |
ci results in caspase-3 activation, tubular injury, and apoptosis. |
2011-07-26 |
2023-08-12 |
Not clear |
| Kultigin Turkmen, Jessica Martin, Ali Akcay, Quocan Nguyen, Kameswaran Ravichandran, Sarah Faubel, Arijana Pacic, Danica Ljubanović, Charles L Edelstein, Alkesh Jan. Apoptosis and autophagy in cold preservation ischemia. Transplantation. vol 91. issue 11. 2011-07-26. PMID:21577181. |
we sought to determine apoptosis and autophagic flux in ci. |
2011-07-26 |
2023-08-12 |
Not clear |
| In-Su Kim, Hyun-Myung Ko, Sushruta Koppula, Byung-Wook Kim, Dong-Kug Cho. Protective effect of Chrysanthemum indicum Linne against 1-methyl-4-phenylpridinium ion and lipopolysaccharide-induced cytotoxicity in cellular model of Parkinson's disease. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 4. 2011-07-01. PMID:21219959. |
the molecular mechanisms involved by ci might involve its inhibitory actions both on neuronal apoptosis and neuroinflammatory nf-κb/iκb-α signaling pathway. |
2011-07-01 |
2023-08-12 |
Not clear |
| S V Michurina, Iu I Borodin, V A Trufakin, A D Belkin, G M Vakulin, P M Larionov, A V Shurlygin. [Micro- and ultrastructural characteristics of liver and nuclear endonuclease activity in hepatocytes after the combined exposure to industrial frequency magnetic field and continuous illumination]. Morfologiia (Saint Petersburg, Russia). vol 137. issue 5. 2011-05-12. PMID:21500433. |
the effects of combined action of the industrial frequency magnetic field (mf) and continuous illumination (ci) on microcirculation, ultrastructural features of liver cells and apoptosis were studied in wistar rats (n=56). |
2011-05-12 |
2023-08-12 |
rat |
| Alkesh Jani, Michael Zimmerman, Jessica Martin, Li Lu, Kultigin Turkmen, Kameswaran Ravichandran, Arijana Pacic, Danica Ljubanović, Charles L Edelstei. Perfusion storage reduces apoptosis in a porcine kidney model of donation after cardiac death. Transplantation. vol 91. issue 2. 2011-02-23. PMID:21200363. |
in a porcine model of dcd, we hypothesized that dcd kidneys have increased caspase-1 due to warm ischemia (wi) and increased caspase-3 and apoptosis due to ci. |
2011-02-23 |
2023-08-12 |
Not clear |
| MaLing Gou, Ke Men, Juan Zhang, YuHua Li, Jia Song, Shan Luo, HuaShan Shi, YanJun Wen, Gang Guo, MeiJuan Huang, Xia Zhao, ZhiYong Qian, YuQuan We. Efficient inhibition of C-26 colon carcinoma by VSVMP gene delivered by biodegradable cationic nanogel derived from polyethyleneimine. ACS nano. vol 4. issue 10. 2011-02-02. PMID:20839784. |
intraperitoneal injection of pvsvmp/hpei complexes efficiently inhibited the abdominal metastases of c-26 colon carcinoma through apoptosis induction (mean tumor weight in mice treated with pvsvmp/hpei complex = 0.93 g and in control mice = 3.28 g, difference = 2.35 g, 95% confidence interval [ci] = 1.75-2.95 g, p < 0.001) and prolonged the survival of treated mice. |
2011-02-02 |
2023-08-12 |
mouse |
| Lei Zhang, Yan Liu, Xiao Ting Lu, Xin Sheng Xu, Yu Xia Zhao, Xiao Ping Ji, Peng Fei Zhang, Chun Xi Liu, Meng Xiong Tang, Wen Qiang Chen, Yun Zhan. Intraplaque injection of Ad5-CMV.p53 aggravates local inflammation and leads to plaque instability in rabbits. Journal of cellular and molecular medicine. vol 13. issue 8B. 2010-07-19. PMID:19602038. |
however, a binary logistic regression model revealed that hs-crp concentration rather than apoptosis rate played an independent role in plaque rupture with an odds ratio as 1.314 (95% ci: 1.041-1.657, p = 0.021), and there were high positive correlations between inflammatory biomarkers (hs-crp or mcp-1) and apoptosis (r(2) = 0.761, and r(2) = 0.557, respectively, both p < 0.01). |
2010-07-19 |
2023-08-12 |
Not clear |
| Hui-fang Ma, Xiu-jun Ren, Ya Tu, Lei Zho. [Effect of electroacupuncture on the expression of hippocampal calbindin-D 28 K in hyperlipemia rats with concurrent cerebral ischemia]. Zhen ci yan jiu = Acupuncture research. vol 35. issue 1. 2010-06-15. PMID:20458902. |
to observe the effect of electroacupuncture (ea) on calbindin d28 k(cb) expression and apoptosis in hippocampus in hyperlipemia rats with concomitant cerebral ischemia (ci). |
2010-06-15 |
2023-08-12 |
rat |
| Asfar S Azmi, Amro Aboukameel, Sanjeev Banerjee, Zhiwei Wang, Momin Mohammad, Jack Wu, Shaomeng Wang, Dajun Yang, Philip A Philip, Fazlul H Sarkar, Ramzi M Mohamma. MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function. European journal of cancer (Oxford, England : 1990). vol 46. issue 6. 2010-06-14. PMID:20156675. |
mi-319-cisplatin combination synergistically suppressed cell growth (mtt combination index [ci]<1) and colony formation (clonogenic assay) and induced apoptosis. |
2010-06-14 |
2023-08-12 |
human |
| G J Leclerc, C Mou, G M Leclerc, A M Mian, J C Barred. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy. Leukemia. vol 24. issue 3. 2010-03-30. PMID:20072153. |
combination treatment with mtx plus saha significantly increased cytotoxicity and apoptosis in b- and t-all cell lines as compared with each drug alone (ci
| 2010-03-30 |
2023-08-12 |
Not clear |
|
| Young-Yim Kim, Chul-Kee Park, Seung-Ki Kim, Ji-Hoon Phi, Jin-Hyun Kim, Chae-Yong Kim, Kyu-Chang Wang, Byung-Kyu Ch. CKD-602, a camptothecin derivative, inhibits proliferation and induces apoptosis in glioma cell lines. Oncology reports. vol 21. issue 6. 2009-07-09. PMID:19424618. |
susceptibility to ckd-602 at 48 h after treatment varied among the four cell lines and their ic50 value was as follows: 9.07 nm (95% ci 0.18-37.42) for ln229, 14.57 nm (95% ci 0.86-47.33) for u251 mg, 29.13 nm (95% ci 0.35-101.23) for u343 mg, and 84.66 nm (95% ci 34.63-148.25) for u87 mg. ckd-602 induced cell cycle arrest at g2 phase and produced antiproliferative activity and apoptosis in all cell lines. |
2009-07-09 |
2023-08-12 |
human |
| D M Toro-Nieves, Y Rodriguez, M Plaud, P Ciborowski, F Duan, J Pérez Laspiur, V Wojna, L M Melénde. Proteomic analyses of monocyte-derived macrophages infected with human immunodeficiency virus type 1 primary isolates from Hispanic women with and without cognitive impairment. Journal of neurovirology. vol 15. issue 1. 2009-05-26. PMID:19115125. |
the mdm proteins linked to infection with ci strains were related to apoptosis, chemotaxis, inflammation, and redox metabolism. |
2009-05-26 |
2023-08-12 |
human |
| Rita Ghosh, Manonmani Ganapathy, William L Alworth, Daniel C Chan, Addanki P Kuma. Combination of 2-methoxyestradiol (2-ME2) and eugenol for apoptosis induction synergistically in androgen independent prostate cancer cells. The Journal of steroid biochemistry and molecular biology. vol 113. issue 1-2. 2009-04-15. PMID:19084597. |
combining 2-me(2) with eugenol (i) inhibited growth of prostate cancer cells and induced apoptosis at lower concentrations than either single agent alone; (ii) analysis of the data using combination index (ci) showed ci values of 0.4 indicating strong synergistic interaction; (iii) increased population of cells g(2)/m phase by 4.5-fold (p=0.01); (iv) significantly reduced expression of antiapoptotic protein bcl-2 and enhanced expression of proapoptotic protein bax. |
2009-04-15 |
2023-08-12 |
human |