| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jinsong Yang, Wei Chen, Yi Sun, Pincang Xia, Jin Liu, Wenchang Zhan. The role of microRNAs in regulating cadmium-induced apoptosis by targeting Bcl-2 in IEC-6 cells. Toxicology and applied pharmacology. vol 432. 2021-11-08. PMID:34662668. |
overall, the results demonstrated that cd exposure could induce apoptosis in iec-6 cells. |
2021-11-08 |
2023-08-13 |
Not clear |
| Rui-Feng Fan, Zi-Fa Li, Dong Zhang, Zhen-Yong Wan. Involvement of Nrf2 and mitochondrial apoptotic signaling in trehalose protection against cadmium-induced kidney injury. Metallomics : integrated biometal science. vol 12. issue 12. 2021-11-02. PMID:33226392. |
herein, an in vivo model of tr antagonizing cd nephrotoxicity was established and the indictors related to kidney function, oxidative stress, and apoptosis were detected to investigate the molecular mechanism underlying the tr-protection against cd-induced kidney injury of rats. |
2021-11-02 |
2023-08-13 |
rat |
| Zhineng Wang, Ying Sun, Wenbo Yao, Qian Ba, Hui Wan. Effects of Cadmium Exposure on the Immune System and Immunoregulation. Frontiers in immunology. vol 12. 2021-11-01. PMID:34354707. |
cd acts as an immunotoxic agent by regulating the activity and apoptosis of immune cells, altering the secretion of immune cytokines, inducing reactive oxygen species (ros) production and oxidative stress, changing the frequency of t lymphocyte subsets, and altering the production of selective antibodies in immune cells. |
2021-11-01 |
2023-08-13 |
Not clear |
| Yulan Yan, Lijuan Jia, Jin Zhang, Yang Liu, Xuefeng B. Effect of recombinant Newcastle disease virus transfection on lung adenocarcinoma A549 cells Oncology letters. vol 8. issue 6. 2021-10-21. PMID:25364430. |
following rl-rvg transfection, rvg and ndv gene expression, decreased tumor growth, subcutaneous tumor necrosis, tumor apoptosis and an increased number of cluster of differentiation (cd)3 |
2021-10-21 |
2023-08-13 |
mouse |
| Jing Fang, Shenglan Xie, Zhuo Chen, Fengyuan Wang, Kejie Chen, Zhicai Zuo, Hengmin Cui, Hongrui Guo, Ping Ouyang, Zhengli Chen, Chao Huang, Wentao Liu, Yi Gen. Protective Effect of Vitamin E on Cadmium-Induced Renal Oxidative Damage and Apoptosis in Rats. Biological trace element research. vol 199. issue 12. 2021-10-18. PMID:33565019. |
it is known that ve exerts a protective effect on renal oxidative damage caused by cd, but the effect and mechanism of ve on apoptosis are not fully understood. |
2021-10-18 |
2023-08-13 |
rat |
| Chong Xu, Sujuan Chen, Ming Xu, Xiaoling Chen, Xiaoxue Wang, Hai Zhang, Xiaoqing Dong, Ruijie Zhang, Xin Chen, Wei Gao, Shile Huang, Long Che. Cadmium Impairs Autophagy Leading to Apoptosis by Ca Neurochemical research. vol 46. issue 8. 2021-10-18. PMID:34021889. |
further investigation demonstrated that cd activated jnk pathway contributing to autophagosome expansion-dependent neuronal apoptosis. |
2021-10-18 |
2023-08-13 |
Not clear |
| Massimo Venditti, Mariem Ben Rhouma, Maria Zelinda Romano, Imed Messaoudi, Russel J Reiter, Sergio Minucc. Altered Expression of DAAM1 and PREP Induced by Cadmium Toxicity Is Counteracted by Melatonin in the Rat Testis. Genes. vol 12. issue 7. 2021-10-18. PMID:34208970. |
this report confirms that cd increased oxidative stress and apoptosis of germ and somatic cells and provoked testicular injury, as documented by biomolecular and histological alterations, i.e., cat and sod activity, the protein level of steroidogenic enzymes (star and 3β-hsd), and morphometric parameters. |
2021-10-18 |
2023-08-13 |
human |
| Dongxu Han, Nuan Song, Wei Wang, Ting Chen, Zhiying Mia. Subacute cadmium exposure modulates Th1 polarization to trigger ER stress-induced porcine hepatocyte apoptosis via regulation of miR-369-TNFα axis. Environmental science and pollution research international. 2021-10-14. PMID:34648162. |
cadmium (cd), as a common environmental pollutant, has been reported to cause t lymphocyte dysfunction and cell apoptosis in multiple organs. |
2021-10-14 |
2023-08-13 |
Not clear |
| Dongxu Han, Nuan Song, Wei Wang, Ting Chen, Zhiying Mia. Subacute cadmium exposure modulates Th1 polarization to trigger ER stress-induced porcine hepatocyte apoptosis via regulation of miR-369-TNFα axis. Environmental science and pollution research international. 2021-10-14. PMID:34648162. |
however, whether subacute cd exposure can induce apoptosis of hepatocytes and the relationship with th1/th2 imbalance were still unclear. |
2021-10-14 |
2023-08-13 |
Not clear |
| Ping Zhong, Jin Liu, Hong Li, Senbin Lin, Lingfeng Zeng, Lingfeng Luo, Minxia Wu, Wenchang Zhan. MicroRNA-204-5p regulates apoptosis by targeting Bcl2 in rat ovarian granulosa cells exposed to cadmium†. Biology of reproduction. vol 103. issue 3. 2021-10-11. PMID:32500147. |
this study aimed to investigate whether cadmium (cd) cytotoxicity in rat ovarian granulosa cells (ogcs) is mediated through apoptosis or autophagy and to determine the role of micrornas (mirnas) in cd cytotoxicity. |
2021-10-11 |
2023-08-13 |
rat |
| Ping Zhong, Jin Liu, Hong Li, Senbin Lin, Lingfeng Zeng, Lingfeng Luo, Minxia Wu, Wenchang Zhan. MicroRNA-204-5p regulates apoptosis by targeting Bcl2 in rat ovarian granulosa cells exposed to cadmium†. Biology of reproduction. vol 103. issue 3. 2021-10-11. PMID:32500147. |
as the cd concentration increased, ogc apoptosis increased. |
2021-10-11 |
2023-08-13 |
rat |
| Ping Zhong, Jin Liu, Hong Li, Senbin Lin, Lingfeng Zeng, Lingfeng Luo, Minxia Wu, Wenchang Zhan. MicroRNA-204-5p regulates apoptosis by targeting Bcl2 in rat ovarian granulosa cells exposed to cadmium†. Biology of reproduction. vol 103. issue 3. 2021-10-11. PMID:32500147. |
in addition, cd promoted apoptosis by decreasing the mrna and protein expression levels of inhibition of b-cell lymphoma 2 (bcl2). |
2021-10-11 |
2023-08-13 |
rat |
| Ping Zhong, Jin Liu, Hong Li, Senbin Lin, Lingfeng Zeng, Lingfeng Luo, Minxia Wu, Wenchang Zhan. MicroRNA-204-5p regulates apoptosis by targeting Bcl2 in rat ovarian granulosa cells exposed to cadmium†. Biology of reproduction. vol 103. issue 3. 2021-10-11. PMID:32500147. |
our findings suggest that cd is cytotoxic to rat ogcs, and mitochondrial apoptosis rather than autophagy mediates cd-induced damage to ogcs. |
2021-10-11 |
2023-08-13 |
rat |
| Kumari Pragati Nanda, Hena Firdau. Dietary cadmium (Cd) reduces hemocyte level by induction of apoptosis in Drosophila melanogaster. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 250. 2021-10-08. PMID:34517133. |
dietary cadmium (cd) reduces hemocyte level by induction of apoptosis in drosophila melanogaster. |
2021-10-08 |
2023-08-13 |
cat |
| Kumari Pragati Nanda, Hena Firdau. Dietary cadmium (Cd) reduces hemocyte level by induction of apoptosis in Drosophila melanogaster. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 250. 2021-10-08. PMID:34517133. |
our results suggest a negative impact of cd exposure on the hemocytes of the drosophila larvae culminating in their lowered count by induction of apoptosis. |
2021-10-08 |
2023-08-13 |
cat |
| Yan Huang, Yanping Dai, Min Li, Lulu Guo, Chulin Cao, Yuting Huang, Rui Ma, Shengyue Qiu, Xiaoyi Su, Kai Zhong, Yina Huang, Hong Gao, Qian B. Exposure to cadmium induces neuroinflammation and impairs ciliogenesis in hESC-derived 3D cerebral organoids. The Science of the total environment. vol 797. 2021-09-28. PMID:34303983. |
our study identified that cd exposure specifically induced apoptosis in neurons and inhibited the proliferation of neural progenitor cells, but neural differentiation was not significantly affected in cerebral organoids. |
2021-09-28 |
2023-08-13 |
human |
| Laorrat Phuapittayalert, Nathamon Tanasrivaroottanun, Wiphawi Hipkaeo, Wisa Supanpaiboon, Natthiya Sakulsa. Increased expression of apoptotic markers in human full-term placenta after exposure to elevated environmental cadmium levels during pregnancy. Environmental science and pollution research international. vol 28. issue 37. 2021-09-24. PMID:33991298. |
collectively, our findings suggest that the exposure of pregnant women to environmental cd might induce cd to be transferred to the body and then accumulated in the placenta, resulting in disturbance of the placental function and eventual apoptosis. |
2021-09-24 |
2023-08-13 |
human |
| Xiaoling Chen, Wen Wu, Baoming Gong, Long Hou, Xiaoqing Dong, Chong Xu, Rui Zhao, Qianyun Yu, Zhihan Zhou, Shile Huang, Long Che. Metformin attenuates cadmium-induced neuronal apoptosis in vitro via blocking ROS-dependent PP5/AMPK-JNK signaling pathway. Neuropharmacology. vol 175. 2021-09-23. PMID:32209321. |
cadmium (cd), a toxic environment contaminant, induces reactive oxygen species (ros)-mediated neuronal apoptosis and consequential neurodegenerative disorders. |
2021-09-23 |
2023-08-13 |
Not clear |
| Shuangquan Wen, Li Wang, Hui Zou, Jianhong Gu, Ruilong Song, Jianchun Bian, Yan Yuan, Zongping Li. Puerarin Attenuates Cadmium-Induced Neuronal Injury via Stimulating Cadmium Excretion, Inhibiting Oxidative Stress and Apoptosis. Biomolecules. vol 11. issue 7. 2021-09-21. PMID:34356602. |
our results demonstrate that pur exerted its neuroprotective effects by stimulating cd excretion, ameliorating cd-induced oxidative stress and apoptosis in rat cerebral cortical neurons. |
2021-09-21 |
2023-08-13 |
rat |
| Ankit Verma, Srinivas Pittala, Belal Alhozeel, Anna Shteinfer-Kuzmine, Ehud Ohana, Rajeev Gupta, Jay H Chung, Varda Shoshan-Barmat. The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-09-14. PMID:34217890. |
vdac1, which controls metabolism, lipids transport, apoptosis, and inflammasome activation, is overexpressed in the colon of cd and uc patients and dss-treated mice. |
2021-09-14 |
2023-08-13 |
mouse |