Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kumari Pragati Nanda, Hena Firdau. Dietary cadmium (Cd) reduces hemocyte level by induction of apoptosis in Drosophila melanogaster. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 250. 2021-10-08. PMID:34517133. |
our results suggest a negative impact of cd exposure on the hemocytes of the drosophila larvae culminating in their lowered count by induction of apoptosis. |
2021-10-08 |
2023-08-13 |
cat |
Yan Huang, Yanping Dai, Min Li, Lulu Guo, Chulin Cao, Yuting Huang, Rui Ma, Shengyue Qiu, Xiaoyi Su, Kai Zhong, Yina Huang, Hong Gao, Qian B. Exposure to cadmium induces neuroinflammation and impairs ciliogenesis in hESC-derived 3D cerebral organoids. The Science of the total environment. vol 797. 2021-09-28. PMID:34303983. |
our study identified that cd exposure specifically induced apoptosis in neurons and inhibited the proliferation of neural progenitor cells, but neural differentiation was not significantly affected in cerebral organoids. |
2021-09-28 |
2023-08-13 |
human |
Laorrat Phuapittayalert, Nathamon Tanasrivaroottanun, Wiphawi Hipkaeo, Wisa Supanpaiboon, Natthiya Sakulsa. Increased expression of apoptotic markers in human full-term placenta after exposure to elevated environmental cadmium levels during pregnancy. Environmental science and pollution research international. vol 28. issue 37. 2021-09-24. PMID:33991298. |
collectively, our findings suggest that the exposure of pregnant women to environmental cd might induce cd to be transferred to the body and then accumulated in the placenta, resulting in disturbance of the placental function and eventual apoptosis. |
2021-09-24 |
2023-08-13 |
human |
Xiaoling Chen, Wen Wu, Baoming Gong, Long Hou, Xiaoqing Dong, Chong Xu, Rui Zhao, Qianyun Yu, Zhihan Zhou, Shile Huang, Long Che. Metformin attenuates cadmium-induced neuronal apoptosis in vitro via blocking ROS-dependent PP5/AMPK-JNK signaling pathway. Neuropharmacology. vol 175. 2021-09-23. PMID:32209321. |
cadmium (cd), a toxic environment contaminant, induces reactive oxygen species (ros)-mediated neuronal apoptosis and consequential neurodegenerative disorders. |
2021-09-23 |
2023-08-13 |
Not clear |
Shuangquan Wen, Li Wang, Hui Zou, Jianhong Gu, Ruilong Song, Jianchun Bian, Yan Yuan, Zongping Li. Puerarin Attenuates Cadmium-Induced Neuronal Injury via Stimulating Cadmium Excretion, Inhibiting Oxidative Stress and Apoptosis. Biomolecules. vol 11. issue 7. 2021-09-21. PMID:34356602. |
our results demonstrate that pur exerted its neuroprotective effects by stimulating cd excretion, ameliorating cd-induced oxidative stress and apoptosis in rat cerebral cortical neurons. |
2021-09-21 |
2023-08-13 |
rat |
Ankit Verma, Srinivas Pittala, Belal Alhozeel, Anna Shteinfer-Kuzmine, Ehud Ohana, Rajeev Gupta, Jay H Chung, Varda Shoshan-Barmat. The role of the mitochondrial protein VDAC1 in inflammatory bowel disease: a potential therapeutic target. Molecular therapy : the journal of the American Society of Gene Therapy. 2021-09-14. PMID:34217890. |
vdac1, which controls metabolism, lipids transport, apoptosis, and inflammasome activation, is overexpressed in the colon of cd and uc patients and dss-treated mice. |
2021-09-14 |
2023-08-13 |
mouse |
Łukasz Kopiasz, Katarzyna Dziendzikowska, Małgorzata Gajewska, Michał Oczkowski, Kinga Majchrzak-Kuligowska, Tomasz Królikowski, Joanna Gromadzka-Ostrowsk. Effects of Dietary Oat Beta-Glucans on Colon Apoptosis and Autophagy through TLRs and Dectin-1 Signaling Pathways-Crohn's Disease Model Study. Nutrients. vol 13. issue 2. 2021-09-09. PMID:33499397. |
the aim of this study was to determine the time-dependent effects of dietary oat beta-glucans on colon apoptosis and autophagy in the cd rat model. |
2021-09-09 |
2023-08-13 |
rat |
Shuangquan Wen, Li Wang, Wenhua Zhang, Mingchang Xu, Ruilong Song, Hui Zou, Jianhong Gu, Jianchun Bian, Yan Yuan, Zongping Li. Induction of mitochondrial apoptosis pathway mediated through caspase-8 and c-Jun N-terminal kinase by cadmium-activated Fas in rat cortical neurons. Metallomics : integrated biometal science. vol 13. issue 7. 2021-09-09. PMID:34185081. |
cadmium (cd) is a toxic metal and an environmental pollutant and can cause neurotoxicity by inducing apoptosis. |
2021-09-09 |
2023-08-13 |
rat |
Shuangquan Wen, Li Wang, Wenhua Zhang, Mingchang Xu, Ruilong Song, Hui Zou, Jianhong Gu, Jianchun Bian, Yan Yuan, Zongping Li. Induction of mitochondrial apoptosis pathway mediated through caspase-8 and c-Jun N-terminal kinase by cadmium-activated Fas in rat cortical neurons. Metallomics : integrated biometal science. vol 13. issue 7. 2021-09-09. PMID:34185081. |
in vitro, cd induced apoptosis in primary cortical neurons by activating caspase-8, jnk, and the mitochondrial apoptotic pathway. |
2021-09-09 |
2023-08-13 |
rat |
Shuangquan Wen, Li Wang, Wenhua Zhang, Mingchang Xu, Ruilong Song, Hui Zou, Jianhong Gu, Jianchun Bian, Yan Yuan, Zongping Li. Induction of mitochondrial apoptosis pathway mediated through caspase-8 and c-Jun N-terminal kinase by cadmium-activated Fas in rat cortical neurons. Metallomics : integrated biometal science. vol 13. issue 7. 2021-09-09. PMID:34185081. |
fas knockdown enhanced cell viability in the presence of cd and inhibited apoptosis by blocking cd-activated fas, caspase-8, and jnk. |
2021-09-09 |
2023-08-13 |
rat |
Doudou Jing, Wei Wu, Xiangyu Deng, Yizhong Peng, Wenbo Yang, Donghua Huang, Zengwu Shao, Dong Zhen. FoxO1a mediated cadmium-induced annulus fibrosus cells apoptosis contributes to intervertebral disc degeneration in smoking. Journal of cellular physiology. vol 236. issue 1. 2021-09-01. PMID:32654176. |
in the current study, we demonstrated that cd induced the apoptosis of annulus fibrosus (af) cells, which contributed to intervertebral disc degeneration (ivdd). |
2021-09-01 |
2023-08-13 |
Not clear |
Doudou Jing, Wei Wu, Xiangyu Deng, Yizhong Peng, Wenbo Yang, Donghua Huang, Zengwu Shao, Dong Zhen. FoxO1a mediated cadmium-induced annulus fibrosus cells apoptosis contributes to intervertebral disc degeneration in smoking. Journal of cellular physiology. vol 236. issue 1. 2021-09-01. PMID:32654176. |
specifically, cd induced the nuclear translocation of foxo1a, which drives af cells apoptosis through mitochondrial-related pathway. |
2021-09-01 |
2023-08-13 |
Not clear |
Yulan Ye, Liping Zhang, Tong Hu, Juan Yin, Lijuan Xu, Zhi Pang, Weichang Che. CircRNA_103765 acts as a proinflammatory factor via sponging miR-30 family in Crohn's disease. Scientific reports. vol 11. issue 1. 2021-08-27. PMID:33436852. |
here we report the potential roles of hsa_circrna_103765 in regulating cell apoptosis induced by tnf-α in crohn's disease (cd). |
2021-08-27 |
2023-08-13 |
human |
Suryakant Niture, Minghui Lin, Qi Qi, John T Moore, Keith E Levine, Reshan A Fernando, Deepak Kuma. Role of Autophagy in Cadmium-Induced Hepatotoxicity and Liver Diseases. Journal of toxicology. vol 2021. 2021-08-24. PMID:34422041. |
cd affects liver function via modulation of cell survival/proliferation, differentiation, and apoptosis. |
2021-08-24 |
2023-08-13 |
human |
Lingna Yi, Juan Dai, Yong Chen, Yeqing Tong, You Li, Guoqing Fu, Zengguang Teng, Jufeng Huang, Chao Quan, Zhibing Zhang, Ting Zhou, Ling Zhang, Yuqin Sh. Reproductive toxicity of cadmium in pubertal male rats induced by cell apoptosis. Toxicology and industrial health. vol 37. issue 8. 2021-08-16. PMID:34128436. |
in the 1 and 3 mg/kg/day cd groups, serum testosterone decreased and apoptosis of testicular cells increased significantly ( |
2021-08-16 |
2023-08-13 |
rat |
Keum-Young So, Byung-Hyun Park, Seon-Hee O. Cytoplasmic sirtuin 6 translocation mediated by p62 polyubiquitination plays a critical role in cadmium-induced kidney toxicity. Cell biology and toxicology. vol 37. issue 2. 2021-07-31. PMID:32394328. |
at earlier times during cd treatment, polyubiquitination of p62 and apoptosis were reduced. |
2021-07-31 |
2023-08-13 |
mouse |
Keum-Young So, Byung-Hyun Park, Seon-Hee O. Cytoplasmic sirtuin 6 translocation mediated by p62 polyubiquitination plays a critical role in cadmium-induced kidney toxicity. Cell biology and toxicology. vol 37. issue 2. 2021-07-31. PMID:32394328. |
cd treatment in mice for 4 weeks promoted p62, sirt6, and lc3-ii accumulation, inducing apoptosis in kidney tissues. |
2021-07-31 |
2023-08-13 |
mouse |
Zhang Yiming, Liu Zhaoyi, Lan Jing, Wang Jinliang, Shen Zhiqiang, Shi Guangliang, Li Sh. Cadmium induces the thymus apoptosis of pigs through ROS-dependent PTEN/PI3K/AKT signaling pathway. Environmental science and pollution research international. vol 28. issue 29. 2021-07-28. PMID:33765263. |
to explore whether cd induces apoptosis in pig thymus and its possible mechanism, the role cd induction of the pten/pi3k/akt pathway in apoptosis of thymus cells was studied in pigs. |
2021-07-28 |
2023-08-13 |
cat |
Markus Ritter, Nikolaus Bresgen, Hubert H Kerschbau. From Pinocytosis to Methuosis-Fluid Consumption as a Risk Factor for Cell Death. Frontiers in cell and developmental biology. vol 9. 2021-07-13. PMID:34249909. |
however, when a cell death (cd) pathway is triggered, cv persistently decreases in isotonic conditions in apoptosis and it increases in necrosis. |
2021-07-13 |
2023-08-13 |
Not clear |
Jitender Kumar Bhardwaj, Harish Panchal, Priyanka Sara. Cadmium as a testicular toxicant: A Review. Journal of applied toxicology : JAT. vol 41. issue 1. 2021-07-05. PMID:32876350. |
in testes, cd has been reported to induce oxidative stress, apoptosis of spermatogenic cells, reduction in androgen production and sperm functions. |
2021-07-05 |
2023-08-13 |
human |