| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhang Yiming, Yin Hang, Shao Bing, Xue Hua, Huang Bo, Liu Honggui, Li Sh. Antagonistic effect of VDR/CREB1 pathway on cadmium-induced apoptosis in porcine spleen. Ecotoxicology and environmental safety. vol 209. 2021-01-29. PMID:33360786. |
the results of this study showed that cd exposure can induce apoptosis by promoting the absorption of various toxic trace elements in the spleen and inducing oxidative stress. |
2021-01-29 |
2023-08-13 |
Not clear |
| Paria Amanpour, Parvin Khodarahmi, Masoud Salehipou. Protective effects of vitamin E on cadmium-induced apoptosis in rat testes. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 3. 2021-01-25. PMID:31620823. |
cadmium (cd) is a toxic metal that is involved in apoptosis. |
2021-01-25 |
2023-08-13 |
rat |
| Paria Amanpour, Parvin Khodarahmi, Masoud Salehipou. Protective effects of vitamin E on cadmium-induced apoptosis in rat testes. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 3. 2021-01-25. PMID:31620823. |
according to the obtained results, cd exerts its apoptotic effects through the mitochondrial pathway by increasing the ratio of bax/bcl-2 and activating caspases in the rats' testes, and vitamin e plays a protective role against cd-induced apoptosis. |
2021-01-25 |
2023-08-13 |
rat |
| Guo-Xiang Zhou, Hua-Long Zhu, Xue-Ting Shi, Yuan Nan, Wei-Bo Liu, Li-Min Dai, Yong-Wei Xiong, Song-Jia Yi, Xue-Lin Cao, De-Xiang Xu, Hua Wan. Autophagy in Sertoli cell protects against environmental cadmium-induced germ cell apoptosis in mouse testes. Environmental pollution (Barking, Essex : 1987). vol 270. 2021-01-21. PMID:33321432. |
cadmium (cd) was an environmental pollutant, which could result in germ cell apoptosis in testes. |
2021-01-21 |
2023-08-13 |
mouse |
| Ke Huang, Yaotang Deng, Wenya Yuan, Jian Geng, Guanghai Wang, Fei Zo. Phospholipase D1 Ameliorates Apoptosis in Chronic Renal Toxicity Caused by Low-Dose Cadmium Exposure. BioMed research international. vol 2020. 2021-01-19. PMID:32337269. |
previous studies have shown that pld1 promotes cell proliferation and inhibits apoptosis, indicating that pld1 may be implicated in the pathogenesis of kidney injury induced by cd. |
2021-01-19 |
2023-08-13 |
rat |
| Fangchao Yin, Yujuan Zhu, Yaqing Wang, Jianhua Qi. Engineering Brain Organoids to Probe Impaired Neurogenesis Induced by Cadmium. ACS biomaterials science & engineering. vol 4. issue 5. 2021-01-15. PMID:33445346. |
with cd exposure, brain organoids displayed induced cell apoptosis, skewed neural differentiation, and varied brain regionalization, indicating the presence of impaired neurogenesis in the human fetal brain. |
2021-01-15 |
2023-08-13 |
human |
| Mei Wang, Xiao-Fei Wang, Ya-Min Li, Na Chen, Yan Fan, Wen-Kai Huang, Shi-Fu Hu, Meng Rao, Yuan-Zhen Zhang, Ping S. Cross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cadmium via PI3K with mTOR-independent pathway. Cell death & disease. vol 11. issue 1. 2021-01-14. PMID:31969557. |
here, generating a sd rats model-treated with cadmium (cd) to mimic environmental exposure on human, we show that autophagy and apoptosis present synchronous change trends in cd-induced testicular injury/self-recovery. |
2021-01-14 |
2023-08-13 |
human |
| Mei Wang, Xiao-Fei Wang, Ya-Min Li, Na Chen, Yan Fan, Wen-Kai Huang, Shi-Fu Hu, Meng Rao, Yuan-Zhen Zhang, Ping S. Cross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cadmium via PI3K with mTOR-independent pathway. Cell death & disease. vol 11. issue 1. 2021-01-14. PMID:31969557. |
conclusively, cross-talk between autophagy and apoptosis regulates testicular injury/recovery induced by cd via pi3k with mtor-independent pathway. |
2021-01-14 |
2023-08-13 |
human |
| Jiaming Zheng, Liling Zhuo, Di Ran, Yonggang Ma, Tongwang Luo, Hongyan Zhao, Ruilong Song, Hui Zou, Jiaqiao Zhu, Jianhong Gu, Jianchun Bian, Yan Yuan, Zongping Li. Cadmium induces apoptosis via generating reactive oxygen species to activate mitochondrial p53 pathway in primary rat osteoblasts. Toxicology. vol 446. 2021-01-14. PMID:33031904. |
we found that treatment with 2 and 5 μm cd for 12 h decreased osteoblast viability and increased apoptosis. |
2021-01-14 |
2023-08-13 |
rat |
| Jiaming Zheng, Liling Zhuo, Di Ran, Yonggang Ma, Tongwang Luo, Hongyan Zhao, Ruilong Song, Hui Zou, Jiaqiao Zhu, Jianhong Gu, Jianchun Bian, Yan Yuan, Zongping Li. Cadmium induces apoptosis via generating reactive oxygen species to activate mitochondrial p53 pathway in primary rat osteoblasts. Toxicology. vol 446. 2021-01-14. PMID:33031904. |
our results indicate that cd can induce apoptosis in osteoblasts by increasing the generation of ros and activating the mitochondrial p53 signaling pathway, and this mechanism requires the transcriptional activation of p53. |
2021-01-14 |
2023-08-13 |
rat |
| Zeyneb Chouit, Dounia Djellal, Souhila Haddad, Mourad Hanfer, Messaoud Hachemi, Zhoura Lakroun, Smail Chafaa, Hamadi Fetoui, Mohamed Kebieche, Rachid Souliman. Potentiation of the apoptotic signaling pathway in both the striatum and hippocampus and neurobehavioral impairment in rats exposed chronically to a low-dose of cadmium. Environmental science and pollution research international. vol 28. issue 3. 2021-01-08. PMID:32915453. |
in conclusion, our results reported that chronic exposure to cd produces behavioral and cognitive perturbations, enhances oxidative stress associated with mitochondrial edema and cyt-c leakage, and, ultimately, potentiates apoptosis signaling pathway in both brain regions in rats. |
2021-01-08 |
2023-08-13 |
rat |
| Kun Wang, Jiao-Yang Ma, Meng-Ying Li, Yi-Shu Qin, Xin-Chen Bao, Cheng-Chen Wang, Dao-Lei Cui, Ping Xiang, Lena Q M. Mechanisms of Cd and Cu induced toxicity in human gastric epithelial cells: Oxidative stress, cell cycle arrest and apoptosis. The Science of the total environment. vol 756. 2021-01-01. PMID:33261865. |
mechanisms of cd and cu induced toxicity in human gastric epithelial cells: oxidative stress, cell cycle arrest and apoptosis. |
2021-01-01 |
2023-08-13 |
human |
| Fotios Papadopoulos, Rafaela Isihou, George A Alexiou, Thomas Tsalios, Evrysthenis Vartholomatos, Georgios S Markopoulos, Chrissa Sioka, Pericles Tsekeris, Athanasios P Kyritsis, Vasiliki Galan. Haloperidol Induced Cell Cycle Arrest and Apoptosis in Glioblastoma Cells. Biomedicines. vol 8. issue 12. 2020-12-29. PMID:33322363. |
apoptosis, using the annexin-propidium iodide (pi), and cell cycle, cluster of differentiation (cd) expression and caspase-8 activation were measured using flow cytometry. |
2020-12-29 |
2023-08-13 |
Not clear |
| Chang Wang, Gaohui Nie, Fan Yang, Jian Chen, Yu Zhuang, Xueyan Dai, Zhiyue Liao, Zhi Yang, Huabin Cao, Chenghong Xing, Guoliang Hu, Caiying Zhan. Molybdenum and cadmium co-induce oxidative stress and apoptosis through mitochondria-mediated pathway in duck renal tubular epithelial cells. Journal of hazardous materials. vol 383. 2020-12-11. PMID:31518807. |
to investigate the combined effects of mo and cd on oxidative stress and mitochondrial apoptosis in primary duck renal tubular epithelial cells, the cells were either treated with (nh |
2020-12-11 |
2023-08-13 |
Not clear |
| Jie Zhang, Min Xu, Weihua Zhou, Dejian Li, Hong Zhang, Yi Chen, Longgui Ning, Yuwei Zhang, Sha Li, Mengli Yu, Yishu Chen, Hang Zeng, Li Cen, Tianyu Zhou, Xinxin Zhou, Chao Lu, Chaohui Yu, Youming Li, Jing Sun, Xiaoni Kong, Zhe She. Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53. The Journal of biological chemistry. vol 295. issue 13. 2020-12-09. PMID:32075910. |
increased intestinal epithelial cell (iec) apoptosis and excessive activation of the p53 signaling pathway is a hallmark of inflammatory bowel disease (ibd), which includes ulcerative colitis (uc) and crohn's disease (cd). |
2020-12-09 |
2023-08-13 |
human |
| Jie Zhang, Min Xu, Weihua Zhou, Dejian Li, Hong Zhang, Yi Chen, Longgui Ning, Yuwei Zhang, Sha Li, Mengli Yu, Yishu Chen, Hang Zeng, Li Cen, Tianyu Zhou, Xinxin Zhou, Chao Lu, Chaohui Yu, Youming Li, Jing Sun, Xiaoni Kong, Zhe She. Deficiency in the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel disease via p53. The Journal of biological chemistry. vol 295. issue 13. 2020-12-09. PMID:32075910. |
to determine whether dj-1 deficiency is involved in the p53 activation that results in iec apoptosis in colitis, here we performed immunostaining, real-time pcr, and immunoblotting analyses to assess dj-1 expression in human uc and cd samples. |
2020-12-09 |
2023-08-13 |
human |
| Sun Jiaxin, Wang Shengchen, Cao Yirong, Wang Shuting, Li Sh. Cadmium exposure induces apoptosis, inflammation and immunosuppression through CYPs activation and antioxidant dysfunction in common carp neutrophils. Fish & shellfish immunology. vol 99. 2020-11-30. PMID:32058096. |
in addition, cd activated cysteinyl aspartate specific proteinases (caspase-3) and induced apoptosis by altering the expression of major genes including mitochondrial pathway factors such as b-cell lymphoma-2 (bcl-2), pro-apoptosis factors bcl-2-associated x (bax), and caspase-9 and death receptor pathways such as fas/fas ligand (fas/fasl), tumour necrosis factor alpha/tumor necrosis factor receptor 1 (tnf-α/tnfr1) and caspase-8. |
2020-11-30 |
2023-08-13 |
Not clear |
| Hongyan Li, Wenjie Xu, Liyun Wu, Bo Dong, Junyan Jin, Dong Han, Xiaoming Zhu, Yunxia Yang, Haokun Liu, Shouqi Xi. Distinct dietary cadmium toxic effects and defense strategies in two strains of gibel carp (Carassius gibelio) revealed by a comprehensive perspective. Chemosphere. vol 261. 2020-11-02. PMID:32707321. |
activation of er stress response positively stimulated the autophagy, then triggering apoptosis in fish after dietary cd exposure. |
2020-11-02 |
2023-08-13 |
human |
| Hongyan Li, Wenjie Xu, Liyun Wu, Bo Dong, Junyan Jin, Dong Han, Xiaoming Zhu, Yunxia Yang, Haokun Liu, Shouqi Xi. Distinct dietary cadmium toxic effects and defense strategies in two strains of gibel carp (Carassius gibelio) revealed by a comprehensive perspective. Chemosphere. vol 261. 2020-11-02. PMID:32707321. |
last but not least, the f strain showed stronger response on antioxidant, er stress and autophagy, but apoptosis were remitted compared with the a strain, implying the f strain showed stronger response but better defense strategies to dietary cd exposure. |
2020-11-02 |
2023-08-13 |
human |
| H J Ni, F F Liu, X Liang, Y L Yin, G Li. The role of zinc chelate of hydroxy analogue of methionine in cadmium toxicity: effects on cadmium absorption on intestinal health in piglets. Animal : an international journal of animal bioscience. vol 14. issue 7. 2020-10-28. PMID:32051055. |
the concentrations of cd and metal trace elements in the gi tract and organs were analysed, as was the relative messenger rna (mrna) expression of inflammatory cytokines and metal element transporters in the small intestine, and epithelial apoptosis in the small intestine. |
2020-10-28 |
2023-08-13 |
Not clear |