| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew A Taylor, Firas Khathayer, Swapan K Ra. Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:31011879. |
quercetin and sodium butyrate synergistically increase apoptosis in rat c6 and human t98g glioblastoma cells through inhibition of autophagy. |
2019-08-12 |
2023-08-13 |
human |
| Matthew A Taylor, Firas Khathayer, Swapan K Ra. Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:31011879. |
this study investigated the efficacy of quercetin (qct) in combination with sodium butyrate (nab) in enhancing apoptosis in rat c6 and human t98g glioblastoma cells though blockage of autophagy under nutrient-starvation. |
2019-08-12 |
2023-08-13 |
human |
| Matthew A Taylor, Firas Khathayer, Swapan K Ra. Quercetin and Sodium Butyrate Synergistically Increase Apoptosis in Rat C6 and Human T98G Glioblastoma Cells Through Inhibition of Autophagy. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:31011879. |
this study demonstrated the therapeutic potentials of a novel combination therapy in inhibiting protective autophagy to enhance apoptosis in rat c6 and human t98g glioblastoma cells. |
2019-08-12 |
2023-08-13 |
human |
| Nadezda V Amaegberi, Galina N Semenkova, Zinaida B Kvacheva, Alexandra G Lisovskaya, Serge V Pinchuk, Oleg I Shadyr. 2-Hexadecenal inhibits growth of C6 glioma cells. Cell biochemistry and function. vol 37. issue 4. 2019-08-12. PMID:31038222. |
this study demonstrated that 2hd inhibits growth of c6 glioma cells due to modification of intracellular processes of signal transduction, cytoskeleton rearrangement, change in the mitotic regimen and apoptosis induction. |
2019-08-12 |
2023-08-13 |
Not clear |
| L A L Maués, G M Alves, N M G Couto, B J M da Silva, M S P Arruda, B M Macchi, C B C Sena, A F Prado, M E Crespo-Lopez, E O Silva, J L M do Nasciment. Flavonoids from the Amazon plant Brosimum acutifolium induce C6 glioma cell line apoptosis by disrupting mitochondrial membrane potential and reducing AKT phosphorylation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 113. 2019-08-06. PMID:30856536. |
flavonoids from the amazon plant brosimum acutifolium induce c6 glioma cell line apoptosis by disrupting mitochondrial membrane potential and reducing akt phosphorylation. |
2019-08-06 |
2023-08-13 |
Not clear |
| Yao Xiao, Lan Cheng, Hong-Jun Xie, Rui-Jun Ju, Xin Wang, Min Fu, Jing-Jing Liu, Xue-Tao L. Vinorelbine cationic liposomes modified with wheat germ agglutinin for inhibiting tumor metastasis in treatment of brain glioma. Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup3. 2019-06-18. PMID:30299160. |
results in vitro demonstrated that the targeting liposomes could induce c6 cells apoptosis, promote drugs across the blood-brain barrier, inhibit the metastasis of tumor cells and increase targeting effects to tumor cells. |
2019-06-18 |
2023-08-13 |
mouse |
| Yue Sun, Haiping Wang, Pan Wang, Kun Zhang, Xiaorui Geng, Quanhong Liu, Xiaobing Wan. Tumor targeting DVDMS-nanoliposomes for an enhanced sonodynamic therapy of gliomas. Biomaterials science. vol 7. issue 3. 2019-06-14. PMID:30601475. |
the irgd-lipo-dvdms exhibited significantly improved drug accumulation in monolayer cells, 3d tumor spheroids and transplanted c6 tumors, thus causing significant glioma cell apoptosis. |
2019-06-14 |
2023-08-13 |
mouse |
| Yan Wang, Hui Wang, Hui Ge, Zhuo Yan. AG-1031 induced autophagic cell death and apoptosis in C6 glioma cells associated with Notch-1 signaling pathway. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575026. |
ag-1031 induced autophagic cell death and apoptosis in c6 glioma cells associated with notch-1 signaling pathway. |
2019-05-08 |
2023-08-13 |
Not clear |
| Yan Wang, Hui Wang, Hui Ge, Zhuo Yan. AG-1031 induced autophagic cell death and apoptosis in C6 glioma cells associated with Notch-1 signaling pathway. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575026. |
results from hoechst 33342 staining and western blot assay indicated that ag-1031 induced c6 cell apoptosis. |
2019-05-08 |
2023-08-13 |
Not clear |
| Yan Wang, Hui Wang, Hui Ge, Zhuo Yan. AG-1031 induced autophagic cell death and apoptosis in C6 glioma cells associated with Notch-1 signaling pathway. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575026. |
these results suggest that ag-1031 may induce autophagic cell death through the inhibition of akt-mtor signaling pathway by down-regulating notch-1 signaling pathway and activating apoptosis in c6 cells via notch-1 signaling, which develops a new target spot to treat glioma in the future. |
2019-05-08 |
2023-08-13 |
Not clear |
| Xiong Zhang, Qi Ni, Ying Wang, Hongwei Fan, Yingbin L. Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells. Biological & pharmaceutical bulletin. vol 41. issue 8. 2019-01-09. PMID:29848900. |
the effect of formononetin in combination with tmz on apoptosis of c6 cells was investigated by flow cytometry. |
2019-01-09 |
2023-08-13 |
human |
| Qian Cheng, Xin Li, Yue Wang, Min Dong, Feng-Huang Zhan, Jing Li. The ceramide pathway is involved in the survival, apoptosis and exosome functions of human multiple myeloma cells in vitro. Acta pharmacologica Sinica. vol 39. issue 4. 2018-09-25. PMID:28858294. |
in this study, we showed that c6 ceramide (an exogenous ceramide supplement, 1.25-40 μmol/l) dose-dependently inhibited the proliferation and promoted the apoptosis in human mm opm2 cell line, which were associated with elevated caspase 3/9 and parp cleavage. |
2018-09-25 |
2023-08-13 |
human |
| Qian Cheng, Xin Li, Yue Wang, Min Dong, Feng-Huang Zhan, Jing Li. The ceramide pathway is involved in the survival, apoptosis and exosome functions of human multiple myeloma cells in vitro. Acta pharmacologica Sinica. vol 39. issue 4. 2018-09-25. PMID:28858294. |
of note, exosomes from c6 ceramide-treated opm2 cells could influence the proliferation and apoptosis of the recipient opm2 cells, which correlated with increased tumor-suppressive exosomal mirs. |
2018-09-25 |
2023-08-13 |
human |
| Mariana Colombo, Fabrício Figueiró, Amanda de Fraga Dias, Helder Ferreira Teixeira, Ana Maria Oliveira Battastini, Letícia Scherer Koeste. Kaempferol-loaded mucoadhesive nanoemulsion for intranasal administration reduces glioma growth in vitro. International journal of pharmaceutics. vol 543. issue 1-2. 2018-09-24. PMID:29605695. |
in addition, kpf-mne reduced c6 glioma cell viability through induction of apoptosis to a greater extent than either free kpf or kpf-ne. |
2018-09-24 |
2023-08-13 |
rat |
| Wei-Cheng Lu, Hui Xie, Xin-Xin Tie, Ruizhe Wang, An-Hua Wu, Feng-Ping Sha. NFAT-1 hyper-activation by methionine enkephalin (MENK) significantly induces cell apoptosis of rats C6 glioma in vivo and in vitro. International immunopharmacology. vol 56. 2018-09-07. PMID:29324390. |
nfat-1 hyper-activation by methionine enkephalin (menk) significantly induces cell apoptosis of rats c6 glioma in vivo and in vitro. |
2018-09-07 |
2023-08-13 |
rat |
| Wei-Cheng Lu, Hui Xie, Xin-Xin Tie, Ruizhe Wang, An-Hua Wu, Feng-Ping Sha. NFAT-1 hyper-activation by methionine enkephalin (MENK) significantly induces cell apoptosis of rats C6 glioma in vivo and in vitro. International immunopharmacology. vol 56. 2018-09-07. PMID:29324390. |
our findings showed that menk could inhibit the growth of rat c6 glioma, prolong median survival times in tumor-bearing rats, and induce glioma cell apoptosis. |
2018-09-07 |
2023-08-13 |
rat |
| Anubha Shukla, Sunil P Trived. An in vitro analysis of the rat C6 glioma cells to elucidate the linear alkylbenzene sulfonate induced oxidative stress and consequent G2/M phase cell cycle arrest and cellular apoptosis. Chemosphere. vol 205. 2018-08-22. PMID:29705635. |
an in vitro analysis of the rat c6 glioma cells to elucidate the linear alkylbenzene sulfonate induced oxidative stress and consequent g2/m phase cell cycle arrest and cellular apoptosis. |
2018-08-22 |
2023-08-13 |
rat |
| Eunmi Hwang, Sangwan Sim, Sang Hyuk Park, Ki Duk Song, Hak-Kyo Lee, Tae-Hwe Heo, Hyun Sik Jun, Sung-Jo Ki. Anti-proliferative effect of Zea mays L. cob extract on rat C6 glioma cells through regulation of glycolysis, mitochondrial ROS, and apoptosis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 98. 2018-08-13. PMID:29306210. |
anti-proliferative effect of zea mays l. cob extract on rat c6 glioma cells through regulation of glycolysis, mitochondrial ros, and apoptosis. |
2018-08-13 |
2023-08-13 |
rat |
| Mehlika Dilek Altıntop, Belgin Sever, Gülşen Akalın Çiftçi, Gülhan Turan-Zitouni, Zafer Asım Kaplancıklı, Ahmet Özdemi. Design, synthesis, in vitro and in silico evaluation of a new series of oxadiazole-based anticancer agents as potential Akt and FAK inhibitors. European journal of medicinal chemistry. vol 155. 2018-08-07. PMID:29966916. |
compounds 2, 6 and 9 were found to be the most potent anticancer agents against a549 and c6 cell lines and therefore their effects on apoptosis, caspase-3 activation, akt, fak, mitochondrial membrane potential and ultrastructural morphological changes were evaluated. |
2018-08-07 |
2023-08-13 |
mouse |
| Lei Chen, Damin Cong, Yongzhe Li, Dan Wang, Qingsong Li, Shaoshan H. Combination of sonodynamic with temozolomide inhibits C6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing NHE-1 expression. Ultrasonics sonochemistry. vol 39. 2018-07-23. PMID:28732990. |
combination of sonodynamic with temozolomide inhibits c6 glioma migration and promotes mitochondrial pathway apoptosis via suppressing nhe-1 expression. |
2018-07-23 |
2023-08-13 |
Not clear |