| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guocai Guo, Ang Tian, Xiaolei Lan, Changqing Fu, Zhiyong Yan, Chao Wan. Nano hydroxyapatite induces glioma cell apoptosis by suppressing NF-κB signaling pathway. Experimental and therapeutic medicine. vol 17. issue 5. 2020-09-29. PMID:30988786. |
flow cytometry revealed that nha (20-100 µg/ml) significantly induced apoptosis and cell cycle g2/m arrest in c6 and u87mg atcc cells (p<0.05). |
2020-09-29 |
2023-08-13 |
human |
| Yuh-Feng Tsai, Yuh-Fung Chen, Chen-Yu Hsiao, Ching-Wen Huang, Chi-Cheng Lu, Shih-Chang Tsai, Jai-Sing Yan. Caspase‑dependent apoptotic death by gadolinium chloride (GdCl3) via reactive oxygen species production and MAPK signaling in rat C6 glioma cells. Oncology reports. vol 41. issue 2. 2020-09-11. PMID:30535448. |
in conclusion, ros production and mapks signaling pathways contribute to gdcl3‑induced caspase cascade‑mediated apoptosis in c6 cells. |
2020-09-11 |
2023-08-13 |
rat |
| Hongqiang Yin, Yu Jiang, Yinguo Zhang, Hui Ge, Zhuo Yan. The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma. Journal of cellular biochemistry. vol 120. issue 11. 2020-09-08. PMID:31219215. |
in our study, we found that ag1601 markedly inhibited proliferation and promoted c6 glioma cell apoptosis in vitro. |
2020-09-08 |
2023-08-13 |
Not clear |
| Hongqiang Yin, Yu Jiang, Yinguo Zhang, Hui Ge, Zhuo Yan. The inhibition of BDNF/TrkB/PI3K/Akt signal mediated by AG1601 promotes apoptosis in malignant glioma. Journal of cellular biochemistry. vol 120. issue 11. 2020-09-08. PMID:31219215. |
k252a, a specific inhibitor of trkb, and ag1601 in combination aggravated c6 glioma cell apoptosis. |
2020-09-08 |
2023-08-13 |
Not clear |
| Euteum Park, Do Kyung Kim, Chun-Sung Kim, Jae-Sung Kim, Seung Kim, Hong Sung Chu. Protective effects of fusidic acid against sodium nitroprusside-induced apoptosis in C6 glial cells. Neuroreport. vol 30. issue 17. 2020-08-06. PMID:31651708. |
protective effects of fusidic acid against sodium nitroprusside-induced apoptosis in c6 glial cells. |
2020-08-06 |
2023-08-13 |
Not clear |
| Dagmar E Ehrnhoefer, Niels H Skotte, Jeanette Reinshagen, Xiaofan Qiu, Björn Windshügel, Priyadarshini Jaishankar, Safia Ladha, Olga Petina, Mehdi Khankischpur, Yen T N Nguyen, Nicholas S Caron, Adelia Razeto, Matthias Meyer Zu Rheda, Yu Deng, Khuong T Huynh, Ilka Wittig, Philip Gribbon, Adam R Renslo, Detlef Geffken, Sheraz Gul, Michael R Hayde. Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound. Cell chemical biology. vol 26. issue 9. 2020-07-27. PMID:31353319. |
aberrant activation of caspase-6 (c6) in the absence of other hallmarks of apoptosis has been demonstrated in cells and tissues from patients with huntington disease (hd) and animal models. |
2020-07-27 |
2023-08-13 |
Not clear |
| Ya Xu, Xiangcai Yang, Shuting Mei, Yi Sun, Jiejing L. Acquisition of temozolomide resistance by the rat C6 glioma cell line increases cell migration and side population phenotype. Oncology reports. vol 42. issue 6. 2020-04-13. PMID:31578583. |
blockade of the abc transporter could increase sensitivity to temozolomide and temozolomide‑induced apoptosis in c6 cells. |
2020-04-13 |
2023-08-13 |
rat |
| Xiao Lin Lin, Kai Li, Zhuo Yang, Baogui Chen, Tao Zhan. Dulcitol suppresses proliferation and migration of hepatocellular carcinoma via regulating SIRT1/p53 pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 66. 2020-03-26. PMID:31786318. |
dulcitol, a natural product extracted from euonymus alatus, was reported that it could induce apoptosis of c6 glioma cells. |
2020-03-26 |
2023-08-13 |
Not clear |
| Wang-Sheng Chen, Lan Hong, Fei Wang, Jian-Jun L. Investigation of dacomitinib on reducing cell necrosis and enhancing cell apoptosis in C6 glioma rat model by MRI. Bioscience reports. vol 39. issue 3. 2020-02-20. PMID:30782784. |
investigation of dacomitinib on reducing cell necrosis and enhancing cell apoptosis in c6 glioma rat model by mri. |
2020-02-20 |
2023-08-13 |
rat |
| Mingwei Q. The Neuroprotective Effect of Steroid Receptor Coactivator-Interacting Protein (SIP) in Astrocyte Model of 1-Methyl-4-Phenylpyridinium (MPP⁺)-Induced Parkinson's Disease. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-17. PMID:31376345. |
sip overexpression relieved mpp⁺-induced cytotoxicity of c6 cells, displayed as increased cell viability and reduced cell apoptosis and reduced ldh release. |
2020-02-17 |
2023-08-13 |
rat |
| Zhenjiang Li, Vishnu Priya Veeraraghavan, Surapaneni Krishna Mohan, Srinivasa Rao Bolla, Hariprasath Lakshmanan, Subramanian Kumaran, Wilson Aruni, Aref Ali Mohammed Aladresi, Omar H M Shair, Sulaiman Ali Alharbi, Arunachalam Chinnathamb. Apoptotic induction and anti-metastatic activity of eugenol encapsulated chitosan nanopolymer on rat glioma C6 cells via alleviating the MMP signaling pathway. Journal of photochemistry and photobiology. B, Biology. vol 203. 2020-02-13. PMID:31931385. |
over all our results authentically confirms eugenol loaded chitosan nanopolymer persuasively induces apoptosis and inhibits metastasis in rat c6 glioma cells. |
2020-02-13 |
2023-08-13 |
rat |
| Yulong Jia, Lei Chen, Dapeng Chi, Damin Cong, Peng Zhou, Jiaqi Jin, Hang Ji, Binbin Liang, Shuai Gao, Shaoshan H. Photodynamic therapy combined with temozolomide inhibits C6 glioma migration and invasion and promotes mitochondrial-associated apoptosis by inhibiting sodium-hydrogen exchanger isoform 1. Photodiagnosis and photodynamic therapy. vol 26. 2020-01-15. PMID:31085295. |
photodynamic therapy combined with temozolomide inhibits c6 glioma migration and invasion and promotes mitochondrial-associated apoptosis by inhibiting sodium-hydrogen exchanger isoform 1. |
2020-01-15 |
2023-08-13 |
Not clear |
| N G Krylova, M S Drobysh, G N Semenkova, T A Kulahava, S V Pinchuk, O I Shadyr. Cytotoxic and antiproliferative effects of thymoquinone on rat C6 glioma cells depend on oxidative stress. Molecular and cellular biochemistry. vol 462. issue 1-2. 2020-01-14. PMID:31493190. |
here, we tested the hypothesis that tq-induced mild oxidative stress provokes c6 glioma cell apoptosis through redox-dependent alteration of mapk proteins. |
2020-01-14 |
2023-08-13 |
rat |
| N G Krylova, M S Drobysh, G N Semenkova, T A Kulahava, S V Pinchuk, O I Shadyr. Cytotoxic and antiproliferative effects of thymoquinone on rat C6 glioma cells depend on oxidative stress. Molecular and cellular biochemistry. vol 462. issue 1-2. 2020-01-14. PMID:31493190. |
tq provoked apoptosis in c6 glioma cells through mitochondrial potential dissipation and permeability transition pore opening. |
2020-01-14 |
2023-08-13 |
rat |
| Jiajun Chen, Yue Zhou, Xiangyu Zhou, Jia Li, Feng Liu, Qingwei Zho. Inhibitory effects of plasmid small interfering RNA targeting signal transducer and activator of transcription‑3 in C6 glioma cells. Molecular medicine reports. vol 20. issue 3. 2020-01-06. PMID:31322201. |
the current study investigated the effect of plasmid small interfering rna (psirna)‑mediated silencing of signal transducer and activator of transcription‑3 (stat3) on the invasion, apoptosis, and expression levels of cyclin d1, caspase‑3 and b‑cell lymphoma‑2 (bcl‑2) in c6 glioma cells. |
2020-01-06 |
2023-08-13 |
Not clear |
| Jiajun Chen, Yue Zhou, Xiangyu Zhou, Jia Li, Feng Liu, Qingwei Zho. Inhibitory effects of plasmid small interfering RNA targeting signal transducer and activator of transcription‑3 in C6 glioma cells. Molecular medicine reports. vol 20. issue 3. 2020-01-06. PMID:31322201. |
taken together, psirna‑stat3 inhibited the migration and invasive abilities, and induced the apoptosis of c6 glioma cells, possibly through regulation of the expression of cyclin d1, caspase‑3 and bcl‑2 proteins. |
2020-01-06 |
2023-08-13 |
Not clear |
| Hyun Joung Lim, Jung Hyun Park, Chulman Jo, Keejung Yoon, Young Ho Ko. Cigarette smoke extracts and cadmium induce COX-2 expression through γ-secretase-mediated p38 MAPK activation in C6 astroglia cells. PloS one. vol 14. issue 2. 2019-11-21. PMID:30794693. |
notch signaling induced by cse and cd induced apoptosis in c6 cells. |
2019-11-21 |
2023-08-13 |
rat |
| Xue Ying, Yahua Wang, Haolun Xu, Xia Li, Helu Yan, Hui Tang, Chen Wen, Yingchun L. The construction of the multifunctional targeting ursolic acids liposomes and its apoptosis effects to C6 glioma stem cells. Oncotarget. vol 8. issue 38. 2019-11-20. PMID:28969057. |
the construction of the multifunctional targeting ursolic acids liposomes and its apoptosis effects to c6 glioma stem cells. |
2019-11-20 |
2023-08-13 |
human |
| Xue Ying, Yahua Wang, Haolun Xu, Xia Li, Helu Yan, Hui Tang, Chen Wen, Yingchun L. The construction of the multifunctional targeting ursolic acids liposomes and its apoptosis effects to C6 glioma stem cells. Oncotarget. vol 8. issue 38. 2019-11-20. PMID:28969057. |
in this research, we chose ursolic acids (ua) as an anti-cancer drug to inhibit the growth of c6 glioma cells, while epigallocatechin 3-gallate(egcg) as the agent that could induce the apoptosis of c6 glioma stem cells. |
2019-11-20 |
2023-08-13 |
human |
| Shuang Hao, Jing Gao, Hui Wang, Yan Zhang, Andrey Pavlov, Hui Ge, Zhuo Yan. AG-1031 and AG-1503 improve cognitive deficits by promoting apoptosis and inhibiting autophagy in C6 glioma model rats. Brain research. vol 1699. 2019-09-30. PMID:29935156. |
ag-1031 and ag-1503 improve cognitive deficits by promoting apoptosis and inhibiting autophagy in c6 glioma model rats. |
2019-09-30 |
2023-08-13 |
rat |