| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sathishbabu Paranthaman, Chinnappa A Uthaiah, Riyaz Ali M Osmani, Umme Hani, Mohammed Ghazwani, Ali H Alamri, Adel Al Fatease, SubbaRao V Madhunapantula, Devegowda Vishkante Gowd. Anti-Proliferative Potential of Quercetin Loaded Polymeric Mixed Micelles on Rat C6 and Human U87MG Glioma Cells. Pharmaceutics. vol 14. issue 8. 2022-08-26. PMID:36015268. |
furthermore, qu-pmms demonstrated superior cellular uptake, inhibited migration, and induced apoptosis when tested against c6 and u87mg cells than pure qu. |
2022-08-26 |
2023-08-14 |
human |
| Sepideh Khaksar, Khadijeh Kiarostami, Shahrzad Alinagh. The Effects of Methanol Extracts of Hyssopus officinalis on Model of Induced Glioblastoma Multiforme (GBM) in Rats. Journal of molecular neuroscience : MN. 2022-08-13. PMID:35963984. |
in addition, cell viability, apoptosis, and cell cycle were evaluated in c6 glioma cell culture. |
2022-08-13 |
2023-08-14 |
rat |
| Chiara Russo, Daniela Barone, Margherita Lavorgna, Concetta Piscitelli, Marcella Macaluso, Severina Pacifico, Simona Piccolella, Antonio Giordano, Marina Isidor. Cytotoxic evaluation and chemical investigation of tomatoes from plants (Solanum lycopersicum L.) grown in uncontaminated and experimentally contaminated soils. Scientific reports. vol 12. issue 1. 2022-07-29. PMID:35906264. |
cell viability (celltiter-glo luminescent assay), enzyme aldehyde dehydrogenase activity (aldeflour assay), cell cycle progression (accuri c6 flow cytometer), apoptosis and necrosis (annexin v-fitc assay) were evaluated on two gastric cancer (ags and nci-n87) and two colorectal cancer (ht-29 and hct 116) cell lines. |
2022-07-29 |
2023-08-14 |
Not clear |
| Coral Estefania Gutiérrez-Almeida, Anne Santerre, Lilia Carolina León-Moreno, Irene Guadalupe Aguilar-García, Rolando Castañeda-Arellano, Sergio Horacio Dueñas-Jiménez, Judith Marcela Dueñas-Jiméne. Proliferation and apoptosis regulation by G protein-coupled estrogen receptor in glioblastoma C6 cells. Oncology letters. vol 24. issue 1. 2022-06-20. PMID:35720489. |
proliferation and apoptosis regulation by g protein-coupled estrogen receptor in glioblastoma c6 cells. |
2022-06-20 |
2023-08-14 |
human |
| Coral Estefania Gutiérrez-Almeida, Anne Santerre, Lilia Carolina León-Moreno, Irene Guadalupe Aguilar-García, Rolando Castañeda-Arellano, Sergio Horacio Dueñas-Jiménez, Judith Marcela Dueñas-Jiméne. Proliferation and apoptosis regulation by G protein-coupled estrogen receptor in glioblastoma C6 cells. Oncology letters. vol 24. issue 1. 2022-06-20. PMID:35720489. |
the present study investigated the effect of the agonists [17β-estradiol (e2) and g1] and antagonist (g15) of gper on proliferation and apoptosis of c6 glioblastoma cells. |
2022-06-20 |
2023-08-14 |
human |
| Coral Estefania Gutiérrez-Almeida, Anne Santerre, Lilia Carolina León-Moreno, Irene Guadalupe Aguilar-García, Rolando Castañeda-Arellano, Sergio Horacio Dueñas-Jiménez, Judith Marcela Dueñas-Jiméne. Proliferation and apoptosis regulation by G protein-coupled estrogen receptor in glioblastoma C6 cells. Oncology letters. vol 24. issue 1. 2022-06-20. PMID:35720489. |
glioblastoma c6 cells express gper, and this receptor modulates cell proliferation and apoptosis. |
2022-06-20 |
2023-08-14 |
human |
| Jinxu Qi, Taichen Liu, Wei Zhao, Xinhua Zheng, Yihong Wan. Synthesis, crystal structure and antiproliferative mechanisms of gallium(iii) complexes with benzoylpyridine thiosemicarbazones. RSC advances. vol 10. issue 32. 2022-05-06. PMID:35518317. |
ga(iii) complex (c6) promotes apoptosis by consuming intracellular iron, enhancing intracellular reactive oxygen species (ros), activating caspase-3/9, releasing cytochromes and apoptotic protease activating factor-1 (apaf-1). |
2022-05-06 |
2023-08-13 |
human |
| Edgar Rangel-López, Benjamín Robles-Bañuelos, Natalia Guadiana-Ramírez, Valeria Alvarez-Garduño, Sonia Galván-Arzate, Cecilia Zazueta, Cimen Karasu, Isaac Túnez, Alexey Tinkov, Michael Aschner, Abel Santamarí. Thallium Induces Antiproliferative and Cytotoxic Activity in Glioblastoma C6 and U373 Cell Cultures via Apoptosis and Changes in Cell Cycle. Neurotoxicity research. 2022-04-27. PMID:35476314. |
thallium induces antiproliferative and cytotoxic activity in glioblastoma c6 and u373 cell cultures via apoptosis and changes in cell cycle. |
2022-04-27 |
2023-08-13 |
Not clear |
| Yuan Zhang, Mei Wang, Xiaotong Zhang, Zhenyi Jiang, Yuanxiang Zhang, Xiangjun Fu, Yanna Li, Danping Cao, Jun Han, Jiucui Ton. Helicid Improves Lipopolysaccharide-Induced Apoptosis of C6 Cells by Regulating SH2D5 DNA Methylation via the CytC/Caspase9/Caspase3 Signaling Pathway. Contrast media & molecular imaging. vol 2022. 2022-02-17. PMID:35173561. |
helicid improves lipopolysaccharide-induced apoptosis of c6 cells by regulating sh2d5 dna methylation via the cytc/caspase9/caspase3 signaling pathway. |
2022-02-17 |
2023-08-13 |
rat |
| Yuan Zhang, Mei Wang, Xiaotong Zhang, Zhenyi Jiang, Yuanxiang Zhang, Xiangjun Fu, Yanna Li, Danping Cao, Jun Han, Jiucui Ton. Helicid Improves Lipopolysaccharide-Induced Apoptosis of C6 Cells by Regulating SH2D5 DNA Methylation via the CytC/Caspase9/Caspase3 Signaling Pathway. Contrast media & molecular imaging. vol 2022. 2022-02-17. PMID:35173561. |
the results showed that helicid regulated the cytc/caspase9/caspase3 signaling pathway and improved the apoptosis indices of c6 cells through the overexpression of sh2d5. |
2022-02-17 |
2023-08-13 |
rat |
| Ravena Pereira do Nascimento, Balbino Lino Dos Santos, Jéssika Alves Oliveira Amparo, Janaina Ribeiro Pereira Soares, Karina Costa da Silva, Monique Reis Santana, Áurea Maria Alves Nunes Almeida, Victor Diógenes Amaral da Silva, Maria de Fátima Dias Costa, Henning Ulrich, Vivaldo Moura-Neto, Giselle Pinto de Faria Lopes, Silvia Lima Cost. Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma. Pharmaceutics. vol 14. issue 1. 2022-01-21. PMID:35057010. |
apigenin and rutin induce apoptosis in c6 cells increasing tnfα, while decreasing il-10 production, denoting a shift from the immunosuppressive th2 to the th1 profile. |
2022-01-21 |
2023-08-13 |
Not clear |
| Suppanut Wongkularb, Tanapol Limboonreung, Patoomratana Tuchinda, Sukumal Chongthammaku. Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells. In vitro cellular & developmental biology. Animal. 2021-12-15. PMID:34907494. |
suppression of pi3k/akt/mtor pathway in chrysoeriol-induced apoptosis of rat c6 glioma cells. |
2021-12-15 |
2023-08-13 |
rat |
| Suppanut Wongkularb, Tanapol Limboonreung, Patoomratana Tuchinda, Sukumal Chongthammaku. Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells. In vitro cellular & developmental biology. Animal. 2021-12-15. PMID:34907494. |
results showed that chrysoeriol significantly decreased cell viability and induced apoptosis in rat c6 glioma cells. |
2021-12-15 |
2023-08-13 |
rat |
| Suppanut Wongkularb, Tanapol Limboonreung, Patoomratana Tuchinda, Sukumal Chongthammaku. Suppression of PI3K/Akt/mTOR pathway in chrysoeriol-induced apoptosis of rat C6 glioma cells. In vitro cellular & developmental biology. Animal. 2021-12-15. PMID:34907494. |
these results suggest that chrysoeriol promote apoptosis in rat c6 glioma cells via suppression of the pi3k/akt/mtor signaling pathway, thereby demonstrating the potential antineoplastic effects of chrysoeriol on glioma cells. |
2021-12-15 |
2023-08-13 |
rat |
| Wei Yin, Ke Zhang, Qinghua Deng, Qingqing Yu, Yanjiao Mao, Ruping Zhao, Shenglin M. AZD3759 inhibits glioma through the blockade of the epidermal growth factor receptor and Janus kinase pathways. Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34635007. |
we found that proliferation was significantly suppressed and that apoptosis and cell cycle arrest were dramatically induced in both c6 and u87 cells by azd3759 in a dose-dependent manner. |
2021-11-23 |
2023-08-13 |
Not clear |
| Sedat Kacar, Ceyhan Hacioglu, Fatih Kar, Varol Sahinturk, Gungor Kanba. Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 73. 2021-11-08. PMID:33675893. |
cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of sirt1 in c6 glioblastoma cells. |
2021-11-08 |
2023-08-13 |
Not clear |
| Liangxiao Wang, Shengnan Tang, Yawen Yu, Yanan Lv, Aiping Wang, Xiuju Yan, Nuannuan Li, Chunjie Sha, Kaoxiang Sun, Youxin L. Intranasal Delivery of Temozolomide-Conjugated Gold Nanoparticles Functionalized with Anti-EphA3 for Glioblastoma Targeting. Molecular pharmaceutics. vol 18. issue 3. 2021-11-02. PMID:33417456. |
in vitro studies showed that anti-epha3-tmz@gnps exhibited significantly enhanced cellular uptake and toxicity, and a higher cell apoptosis ratio has been seen compared with that of tmz (54.9 and 14.1%, respectively) toward glioma cells (c6). |
2021-11-02 |
2023-08-13 |
Not clear |
| Huaiying Zhang, Winant L van Os, Xiaobo Tian, Guangyue Zu, Laís Ribovski, Reinier Bron, Jeroen Bussmann, Alexander Kros, Yong Liu, Inge S Zuhor. Development of curcumin-loaded zein nanoparticles for transport across the blood-brain barrier and inhibition of glioblastoma cell growth. Biomaterials science. vol 9. issue 21. 2021-10-28. PMID:33538729. |
fluorescence microscopy and flow cytometry studies showed that the cur-zpd-g23 nps increased cellular ros production and induced apoptosis of c6 glioma cells. |
2021-10-28 |
2023-08-13 |
Not clear |
| Nedret Altiok, Melike Ersoz, Meral Koyutur. Estradiol induces JNK-dependent apoptosis in glioblastoma cells. Oncology letters. vol 2. issue 6. 2021-10-21. PMID:22848302. |
the results showed that high concentrations of estradiol inhibit growth and induce apoptosis in c6 rat glioma and t98g human glioblastoma cells. |
2021-10-21 |
2023-08-12 |
human |
| Jian-Hua Li, Zhi-Qiang Chen, Zheng Huang, Qi Zhan, Fu-Bin Ren, Jing-Ye Liu, Wu Yue, Zhi Wan. In vitro study of low intensity ultrasound combined with different doses of PDT: Effects on C6 glioma cells. Oncology letters. vol 5. issue 2. 2021-10-21. PMID:23420417. |
the pathway of pdt inducing c6 glioma cell apoptosis includes both the mitochondrial and death receptor pathways. |
2021-10-21 |
2023-08-12 |
Not clear |