| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peng Du, Shengli Hu, Yingxin Cheng, Fei Li, Mei Li, Jiangtao Li, Liang Yi, Hua Fen. Photodynamic therapy leads to death of C6 glioma cells partly through AMPAR. Brain research. vol 1433. 2012-09-12. PMID:22177774. |
we found that pdt increased extracellular glutamate and expression of ampar subunit glur1 and glur2, which might result in ca(2+) influx and apoptosis of c6 cells. |
2012-09-12 |
2023-08-12 |
Not clear |
| Peng Du, Shengli Hu, Yingxin Cheng, Fei Li, Mei Li, Jiangtao Li, Liang Yi, Hua Fen. Photodynamic therapy leads to death of C6 glioma cells partly through AMPAR. Brain research. vol 1433. 2012-09-12. PMID:22177774. |
when ampar antagonist was added, intracellular free calcium reduced and apoptosis rate of c6 cells decreased. |
2012-09-12 |
2023-08-12 |
Not clear |
| Peng Du, Shengli Hu, Yingxin Cheng, Fei Li, Mei Li, Jiangtao Li, Liang Yi, Hua Fen. Photodynamic therapy leads to death of C6 glioma cells partly through AMPAR. Brain research. vol 1433. 2012-09-12. PMID:22177774. |
these results indicate that pdt may lead to death of c6 glioma cells partly through glutamate and its receptors ampar, which induces ca(2+) influx and then cells apoptosis. |
2012-09-12 |
2023-08-12 |
Not clear |
| Shanlou Qiao, Keiko Murakami, Qinghong Zhao, Baoling Wang, Hisao Seo, Hitoshi Yamashita, Xiaotao Li, Takashi Iwamoto, Masatoshi Ichihara, Masataka Yoshin. Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation. Neurochemical research. vol 37. issue 2. 2012-08-13. PMID:21986805. |
mimosine-induced apoptosis in c6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, jnk activation. |
2012-08-13 |
2023-08-12 |
rat |
| Shanlou Qiao, Keiko Murakami, Qinghong Zhao, Baoling Wang, Hisao Seo, Hitoshi Yamashita, Xiaotao Li, Takashi Iwamoto, Masatoshi Ichihara, Masataka Yoshin. Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation. Neurochemical research. vol 37. issue 2. 2012-08-13. PMID:21986805. |
mimosine markedly inhibited proliferation and induced apoptosis of c6 glioma cells in a dose- and time-dependent manner. |
2012-08-13 |
2023-08-12 |
rat |
| Shanlou Qiao, Keiko Murakami, Qinghong Zhao, Baoling Wang, Hisao Seo, Hitoshi Yamashita, Xiaotao Li, Takashi Iwamoto, Masatoshi Ichihara, Masataka Yoshin. Mimosine-induced apoptosis in C6 glioma cells requires the release of mitochondria-derived reactive oxygen species and p38, JNK activation. Neurochemical research. vol 37. issue 2. 2012-08-13. PMID:21986805. |
mimosine was confirmed to show profound effects on apoptosis of c6 glioma cells by ros-regulated mitochondria pathway, and these results bear on the hypothesized potential for mimosine as promising agents in the treatment of malignant gliomas. |
2012-08-13 |
2023-08-12 |
rat |
| Gang Wang, Jun Jie Wang, Guang Yi Yang, Shi Ming Du, Nan Zeng, Dong Sheng Li, Rui Ming Li, Ji Yan Chen, Jin Bo Feng, Shen Hao Yuan, Fang Y. Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death. International journal of nanomedicine. vol 7. 2012-08-06. PMID:22275840. |
quercetin has been shown to induce apoptosis in a number of cancer cell lines, but a quercetin-loaded nanoliposomal formulation with enhanced antitumor activity in c6 glioma cells and its effect on cancer cell death has not been well studied. |
2012-08-06 |
2023-08-12 |
Not clear |
| Chao Ji, Yan-Li Yang, Li He, Bing Gu, Ji-Ping Xia, Wei-Ling Sun, Zhong-Lan Su, Bin Chen, Zhi-Gang B. Increasing ceramides sensitizes genistein-induced melanoma cell apoptosis and growth inhibition. Biochemical and biophysical research communications. vol 421. issue 3. 2012-08-03. PMID:22507982. |
we found that exogenously added cell-permeable short-chain ceramides (c6) dramatically enhanced genistein-induced growth inhibition and apoptosis in cultured melanoma cells. |
2012-08-03 |
2023-08-12 |
Not clear |
| Yu Mi Ha, Min Young Kim, Min Kyu Park, Young Soo Lee, Young Min Kim, Hye Jung Kim, Jae Heun Lee, Ki Churl Chan. Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways. Apoptosis : an international journal on programmed cell death. vol 17. issue 5. 2012-07-26. PMID:22183510. |
thus, we tested our hypothesis that higenamine protects brain injury by inhibition of middle cerebral artery occlusion (mcao)-mediated hmgb1 release in vivo, and glucose/glucose oxidase (gox)-induced apoptosis in c6 cells in vitro due to ho-1 induction. |
2012-07-26 |
2023-08-12 |
rat |
| Yu Mi Ha, Min Young Kim, Min Kyu Park, Young Soo Lee, Young Min Kim, Hye Jung Kim, Jae Heun Lee, Ki Churl Chan. Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways. Apoptosis : an international journal on programmed cell death. vol 17. issue 5. 2012-07-26. PMID:22183510. |
consistent with this, ly 294002, a pi3k inhibitor, inhibited ho-1 induction by higenamine and apoptosis induced by glucose/gox in c6 cells was prevented by higenamine, which effect was reversed by ly 294002. |
2012-07-26 |
2023-08-12 |
rat |
| Yu Mi Ha, Min Young Kim, Min Kyu Park, Young Soo Lee, Young Min Kim, Hye Jung Kim, Jae Heun Lee, Ki Churl Chan. Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways. Apoptosis : an international journal on programmed cell death. vol 17. issue 5. 2012-07-26. PMID:22183510. |
in addition, recombinant high mobility group box 1 induced apoptosis in c6 cells by increasing ratio of bax/bcl-2 and cleaved caspase c, which was inhibited by higenamine, and all of these effects were reversed by co-treatment with znppix. |
2012-07-26 |
2023-08-12 |
rat |
| Kirsten Hattermann, Rolf Mentlein, Janka Held-Feind. CXCL12 mediates apoptosis resistance in rat C6 glioma cells. Oncology reports. vol 27. issue 5. 2012-07-23. PMID:22323084. |
cxcl12 mediates apoptosis resistance in rat c6 glioma cells. |
2012-07-23 |
2023-08-12 |
human |
| Kirsten Hattermann, Rolf Mentlein, Janka Held-Feind. CXCL12 mediates apoptosis resistance in rat C6 glioma cells. Oncology reports. vol 27. issue 5. 2012-07-23. PMID:22323084. |
similarly, cxcl12 protected c6 cells from apoptosis under treatment with higher temozolomide doses. |
2012-07-23 |
2023-08-12 |
human |
| Lili Sun, Li Gu, Shuting Wang, Jifang Yuan, Huimin Yang, Jiawei Zhu, Hong Zhan. N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity. PloS one. vol 7. issue 3. 2012-07-23. PMID:22442667. |
in this study, we investigated the effects of n-acetylcysteine (nac), a precursor of the antioxidant glutathione, on group i mglus activation in apoptosis of glial c6 and mn9d cell lines, and a rat model of parkinson's disease (pd). |
2012-07-23 |
2023-08-12 |
rat |
| Pratibha Gaur, Priya Ranjan, Shipra Sharma, Jenish R Patel, J Bradford Bowzard, Shah K Rahman, Rashmi Kumari, Shivaprakash Gangappa, Jacqueline M Katz, Nancy J Cox, Renu B Lal, Suryaprakash Sambhara, Sunil K La. Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein. The Journal of biological chemistry. vol 287. issue 18. 2012-07-02. PMID:22396546. |
sirna-mediated suppression of c6 resulted in a down-regulation of activated src, fak, and akt, increased apoptosis, and reduced expression of viral proteins and viral titers in influenza virus-infected human lung adenocarcinoma epithelial and normal human bronchial epithelial cells. |
2012-07-02 |
2023-08-12 |
human |
| Tânia R Mielcke, Alessandra Mascarello, Eduardo Filippi-Chiela, Rafael F Zanin, Guido Lenz, Paulo César Leal, Louise Domeneghini Chiaradia, Louise D Chirardia, Rosendo A Yunes, Ricardo J Nunes, Ana M O Battastini, Fernanda B Morrone, Maria M Campo. Activity of novel quinoxaline-derived chalcones on in vitro glioma cell proliferation. European journal of medicinal chemistry. vol 48. 2012-06-12. PMID:22209415. |
flow cytometry analysis demonstrated that incubation of c6 cells with compound 6 led to g1 phase arrest, likely indicating an interference with apoptosis. |
2012-06-12 |
2023-08-12 |
human |
| Joo-Hyun Shin, Ji-Young Jeong, Yinchuan Jin, Il-Doo Kim, Ja-Kyeong Le. p38β MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of αB-crystallin and its anti-apoptotic function. Neuroscience letters. vol 501. issue 3. 2012-05-31. PMID:21777656. |
in these cells, hydrogen peroxide-induced apoptosis was reduced to 44.3% of that obtained from normal c6 cells. |
2012-05-31 |
2023-08-12 |
Not clear |
| Joo-Hyun Shin, Ji-Young Jeong, Yinchuan Jin, Il-Doo Kim, Ja-Kyeong Le. p38β MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of αB-crystallin and its anti-apoptotic function. Neuroscience letters. vol 501. issue 3. 2012-05-31. PMID:21777656. |
repression of αb-crystallin expression by αb-crystallin sirna transfection suppressed the protective effect and recovered caspase 3 activity, indicating that αb-crystallin induction plays a crucial role in the protection against h₂o₂-induced apoptosis observed in p38β-overexpressing c6 astroglioma cells. |
2012-05-31 |
2023-08-12 |
Not clear |
| Jing Xu, Pengjuan Xu, Zhigui Li, Jie Huang, Zhuo Yan. Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells. Journal of biomedical materials research. Part A. vol 100. issue 3. 2012-05-21. PMID:22213249. |
oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in c6 cells. |
2012-05-21 |
2023-08-12 |
human |
| Jing Xu, Pengjuan Xu, Zhigui Li, Jie Huang, Zhuo Yan. Oxidative stress and apoptosis induced by hydroxyapatite nanoparticles in C6 cells. Journal of biomedical materials research. Part A. vol 100. issue 3. 2012-05-21. PMID:22213249. |
the aim of this study was to explore whether ha can inhibit the proliferation and induce the apoptosis of c6 cells. |
2012-05-21 |
2023-08-12 |
human |