| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming Li, Shizhong Zhang, Yuan Zhou, Yanwu Guo, Xiaodan Jiang, Li Mia. Argon-helium cryosurgery for treatment of C6 gliomas in rats and its effect on cellular immunity. Technology in cancer research & treatment. vol 9. issue 1. 2010-04-15. PMID:20082534. |
to explore the cell apoptosis at the glioma foci and the cellullar immunity changes following argon-helium cryosurgery, we established wistar rat models bearing subcutaneous c6 glioma and divided the rats into the normal control (20 rats), sham-operated (32 rats), surgical resection (20 rats), and cryosurgery (32 rats) groups with corresponding treatments. |
2010-04-15 |
2023-08-12 |
rat |
| Chao Tang, Hong-li Xue, Hai-bo Huang, Xiao-gang Wan. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neuroscience letters. vol 470. issue 2. 2010-04-06. PMID:20045721. |
tanshinone iia inhibits constitutive stat3 activation, suppresses proliferation, and induces apoptosis in rat c6 glioma cells. |
2010-04-06 |
2023-08-12 |
rat |
| Chao Tang, Hong-li Xue, Hai-bo Huang, Xiao-gang Wan. Tanshinone IIA inhibits constitutive STAT3 activation, suppresses proliferation, and induces apoptosis in rat C6 glioma cells. Neuroscience letters. vol 470. issue 2. 2010-04-06. PMID:20045721. |
in this study, we evaluate the anti-proliferation and apoptosis inducing effects of tan iia on c6 glioma cells. |
2010-04-06 |
2023-08-12 |
rat |
| Mehari Endale, Sung Dae Kim, Whi Min Lee, Sangseop Kim, Kyoungho Suk, Jae Youl Cho, Hwa Jin Park, Yadav Wagley, Suk Kim, Jae-Wook Oh, Man Hee Rhe. Ischemia induces regulator of G protein signaling 2 (RGS2) protein upregulation and enhances apoptosis in astrocytes. American journal of physiology. Cell physiology. vol 298. issue 3. 2010-04-01. PMID:20032508. |
this study suggests that ischemic stress increases rgs2 expression and that this condition contributes to enhanced apoptosis in c6 cells and primary astrocytes. |
2010-04-01 |
2023-08-12 |
mouse |
| Pengfei Ge, Xunming Ji, Yuchuan Ding, Xiaofei Wang, Shuangliin Fu, Fankai Meng, Xin Jin, Feng Ling, Yinan Lu. Celastrol causes apoptosis and cell cycle arrest in rat glioma cells. Neurological research. vol 32. issue 1. 2010-03-22. PMID:19909582. |
the results demonstrated that celastrol inhibited cell proliferation in a time- and dose-dependent manner, suppressed proteasome chymotrypsin-like activity and induced apoptosis and cell cycle arrest at g2/m phase in c6 cells. |
2010-03-22 |
2023-08-12 |
rat |
| Pengfei Ge, Xunming Ji, Yuchuan Ding, Xiaofei Wang, Shuangliin Fu, Fankai Meng, Xin Jin, Feng Ling, Yinan Lu. Celastrol causes apoptosis and cell cycle arrest in rat glioma cells. Neurological research. vol 32. issue 1. 2010-03-22. PMID:19909582. |
taken together, our data suggest that celastrol can suppress proteasome activity and induce apoptosis and cell cycle arrest in c6 glioma cells, which make it be a potential drug for glioma. |
2010-03-22 |
2023-08-12 |
rat |
| Geise Ribeiro, Marcel Benadiba, Denise de Oliveira Silva, Alison Colquhou. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. Cell biochemistry and function. vol 28. issue 1. 2010-03-19. PMID:19927275. |
the novel ruthenium-gamma-linolenic complex [ru(2)(agla)(4)cl] inhibits c6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. |
2010-03-19 |
2023-08-12 |
rat |
| Geise Ribeiro, Marcel Benadiba, Denise de Oliveira Silva, Alison Colquhou. The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. Cell biochemistry and function. vol 28. issue 1. 2010-03-19. PMID:19927275. |
the properties of ru(2)gla were tested in c6 rat glioma cells by analysing cell number, viability, lipid droplet formation, apoptosis, cell cycle distribution, mitochondrial membrane potential and reactive oxygen species. |
2010-03-19 |
2023-08-12 |
rat |
| Jun Hu, Xiao-Feng Cai, Guangmei Ya. Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein. Cell cycle (Georgetown, Tex.). vol 8. issue 20. 2009-12-21. PMID:19770587. |
here, we have identified that m1, an alphavirus isolated in 1960s, targeted c6 malignant glioma cells for apoptosis. |
2009-12-21 |
2023-08-12 |
Not clear |
| Jun Hu, Xiao-Feng Cai, Guangmei Ya. Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein. Cell cycle (Georgetown, Tex.). vol 8. issue 20. 2009-12-21. PMID:19770587. |
thus, it is indicated that the downregulation of p21(waf1/cip1) mediated c6 apoptosis via overactivation of cdk2. |
2009-12-21 |
2023-08-12 |
Not clear |
| Jun Hu, Xiao-Feng Cai, Guangmei Ya. Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein. Cell cycle (Georgetown, Tex.). vol 8. issue 20. 2009-12-21. PMID:19770587. |
in addition, confocal microscopy showed that p21(waf1/cip1) totally translocated to nucleolus during m1-induced c6 apoptosis. |
2009-12-21 |
2023-08-12 |
Not clear |
| Jun Hu, Xiao-Feng Cai, Guangmei Ya. Alphavirus M1 induces apoptosis of malignant glioma cells via downregulation and nucleolar translocation of p21WAF1/CIP1 protein. Cell cycle (Georgetown, Tex.). vol 8. issue 20. 2009-12-21. PMID:19770587. |
altogether, downregulation and nucleolar translocation of the p21(waf1/cip1) protein played an active role in m1-induced c6 apoptosis. |
2009-12-21 |
2023-08-12 |
Not clear |
| Yumei Liu, Wuqing Ouyang, Ziqiang Zhang, Xuefeng Yang, Shuyan M. [Effects of vinblastine nanoparticles on growth and apoptosis of glioma cell line C6]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 34. issue 14. 2009-12-08. PMID:19894518. |
[effects of vinblastine nanoparticles on growth and apoptosis of glioma cell line c6]. |
2009-12-08 |
2023-08-12 |
Not clear |
| Yumei Liu, Wuqing Ouyang, Ziqiang Zhang, Xuefeng Yang, Shuyan M. [Effects of vinblastine nanoparticles on growth and apoptosis of glioma cell line C6]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 34. issue 14. 2009-12-08. PMID:19894518. |
to compare effects of vinblastine (vlb) nanoparticles (nps) and vlb physiologic saline solution on inhibiting glioma cell lines c6 growth and inducting its apoptosis. |
2009-12-08 |
2023-08-12 |
Not clear |
| Joo-Hyun Shin, Seung-Woo Kim, Chae-Moon Lim, Ji-Young Jeong, Chun-Shu Piao, Ja-Kyeong Le. alphaB-crystallin suppresses oxidative stress-induced astrocyte apoptosis by inhibiting caspase-3 activation. Neuroscience research. vol 64. issue 4. 2009-12-03. PMID:19379782. |
furthermore, the repression of alphab-crystallin expression by alphab-crystallin sirna transfection suppressed this protective effect, indicating that alphab-crystallin is responsible for the protection against h2o2-induced apoptosis in c6 astroglioma cells. |
2009-12-03 |
2023-08-12 |
Not clear |
| Mar Lorente, Arkaitz Carracedo, Sofía Torres, Francesco Natali, Ainara Egia, Sonia Hernández-Tiedra, María Salazar, Cristina Blázquez, Manuel Guzmán, Guillermo Velasc. Amphiregulin is a factor for resistance of glioma cells to cannabinoid-induced apoptosis. Glia. vol 57. issue 13. 2009-10-30. PMID:19229996. |
by analyzing the gene expression profile of two sub-clones of c6 glioma cells with different sensitivity to cannabinoid-induced apoptosis, we found a subset of genes with a marked differential expression in the two sub-clones. |
2009-10-30 |
2023-08-12 |
Not clear |
| Xiuling Xu, Xuesi Chen, Zhanfeng Wang, Xiabin Jin. Ultrafine PEG-PLA fibers loaded with both paclitaxel and doxorubicin hydrochloride and their in vitro cytotoxicity. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. vol 72. issue 1. 2009-09-21. PMID:19027067. |
in vitro cytotoxicity against rat glioma c6 cells indicated that the dual drug combination showed a higher inhibition and apoptosis against c6 cells than a single drug-loaded system, which suggests the promise for multi-drug delivery on combination therapy. |
2009-09-21 |
2023-08-12 |
rat |
| Tzu-Ching Kuo, Jai-Sing Yang, Meng-Wei Lin, Shu-Chun Hsu, Jen-Jyh Lin, Hui-Ju Lin, Te-Chun Hsia, Ching-Lung Liao, Mei-Due Yang, Ming-Jen Fan, W G Wood, Jing-Gung Chun. Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival. The Journal of pharmacology and experimental therapeutics. vol 330. issue 3. 2009-09-21. PMID:19549930. |
emodin inhibited the proliferation and induced apoptosis of c6 cells in a 12-h treatment, but c6 cells survived a 72-h drug treatment, indicating resistance to emodin. |
2009-09-21 |
2023-08-12 |
rat |
| Tzu-Ching Kuo, Jai-Sing Yang, Meng-Wei Lin, Shu-Chun Hsu, Jen-Jyh Lin, Hui-Ju Lin, Te-Chun Hsia, Ching-Lung Liao, Mei-Due Yang, Ming-Jen Fan, W G Wood, Jing-Gung Chun. Emodin has cytotoxic and protective effects in rat C6 glioma cells: roles of Mdr1a and nuclear factor kappaB in cell survival. The Journal of pharmacology and experimental therapeutics. vol 330. issue 3. 2009-09-21. PMID:19549930. |
c6 cells also expressed grp78 to decrease emodin-induced endoplasmic reticulum (er) stress that would cause apoptosis in c6 cells, and grp78 inhibited the expression of gadd153 to enhance the expression of bcl-2 that could balance the er- and mitochondria-induced apoptosis of c6 cells. |
2009-09-21 |
2023-08-12 |
rat |
| Fen Tian, Huijiao Wu, Zhihua Li, Na Wang, Jintao Huang, Chaohong Li, Fukang Xi. Activated PKCalpha/ERK1/2 signaling inhibits tamoxifen-induced apoptosis in C6 cells. Cancer investigation. vol 27. issue 7. 2009-08-25. PMID:19544110. |
activated pkcalpha/erk1/2 signaling inhibits tamoxifen-induced apoptosis in c6 cells. |
2009-08-25 |
2023-08-12 |
human |