| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J A Benítez, L Arregui, P Vergara, J Segovi. Targeted-simultaneous expression of Gas1 and p53 using a bicistronic adenoviral vector in gliomas. Cancer gene therapy. vol 14. issue 10. 2007-11-01. PMID:17599090. |
we showed that the targeted overexpression of gas1 and p53 (adsgas1 and adsp53, respectively) in rat glioma cells (c6) reduced the number of viable cells and induced apoptosis. |
2007-11-01 |
2023-08-12 |
human |
| J A Benítez, L Arregui, P Vergara, J Segovi. Targeted-simultaneous expression of Gas1 and p53 using a bicistronic adenoviral vector in gliomas. Cancer gene therapy. vol 14. issue 10. 2007-11-01. PMID:17599090. |
we suggest that gas1 does not act in combination with p53 in the c6 and u373 glioma cell lines, inducing apoptosis and cell cycle arrest. |
2007-11-01 |
2023-08-12 |
human |
| Sarah F Giardina, Maya Mikami, Farida Goubaeva, Jay Yan. Connexin 43 confers resistance to hydrogen peroxide-mediated apoptosis. Biochemical and biophysical research communications. vol 362. issue 3. 2007-11-01. PMID:17761141. |
c6 cells exposed to hydrogen peroxide (h2o2) or staurosporine demonstrated morphological and biochemical changes consistent with apoptosis, whereas c6 cells expressing cx43 demonstrated relative resistance to h2o2, but not to staurosporine. |
2007-11-01 |
2023-08-12 |
rat |
| Chiung-Huei Peng, Chien-Ning Huang, Shu-Ping Hsu, Chau-Jong Wan. Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells. Toxicology. vol 238. issue 2-3. 2007-10-31. PMID:17651887. |
penta-acetyl geniposide-induced apoptosis involving transcription of ngf/p75 via mapk-mediated ap-1 activation in c6 glioma cells. |
2007-10-31 |
2023-08-12 |
Not clear |
| Chiung-Huei Peng, Chien-Ning Huang, Shu-Ping Hsu, Chau-Jong Wan. Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells. Toxicology. vol 238. issue 2-3. 2007-10-31. PMID:17651887. |
we have demonstrated the herbal derivative penta-acetyl geniposide ((ac)(5)gp) induces c6 glioma cell apoptosis through the critical sphingomyelinase (smase)/nerve growth factor (ngf)/p75 and its downstream signals. |
2007-10-31 |
2023-08-12 |
Not clear |
| Xiao-Jia Huang, Zhen-Qiu Ma, Wei-Ping Zhang, Yun-Bi Lu, Er-Qing We. Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells. The Journal of pharmacy and pharmacology. vol 59. issue 6. 2007-10-04. PMID:17637177. |
here we determined whether dihydroartemisinin inhibits the growth and induces apoptosis of rat c6 glioma cells. |
2007-10-04 |
2023-08-12 |
rat |
| Xiao-Jia Huang, Zhen-Qiu Ma, Wei-Ping Zhang, Yun-Bi Lu, Er-Qing We. Dihydroartemisinin exerts cytotoxic effects and inhibits hypoxia inducible factor-1alpha activation in C6 glioma cells. The Journal of pharmacy and pharmacology. vol 59. issue 6. 2007-10-04. PMID:17637177. |
we found dihydroartemisinin (5-25 microm) inhibited the growth and induced apoptosis of c6 cells in a concentration- and time-dependent manner; however, it was much less toxic to rat primary astrocytes. |
2007-10-04 |
2023-08-12 |
rat |
| Jian Hai, Qi Lin, Yang Lu, Hao Zhang, Jing Y. Induction of apoptosis in rat C6 glioma cells by panaxydol. Cell biology international. vol 31. issue 7. 2007-08-23. PMID:17320424. |
induction of apoptosis in rat c6 glioma cells by panaxydol. |
2007-08-23 |
2023-08-12 |
rat |
| Jian Hai, Qi Lin, Yang Lu, Hao Zhang, Jing Y. Induction of apoptosis in rat C6 glioma cells by panaxydol. Cell biology international. vol 31. issue 7. 2007-08-23. PMID:17320424. |
in conclusion, panaxydol has profound effects on growth and apoptosis of c6 cells, suggesting that panaxydol may be a potential candidate for the treatment of malignant gliomas. |
2007-08-23 |
2023-08-12 |
rat |
| A Isakovic, L Harhaji, D Stevanovic, Z Markovic, M Sumarac-Dumanovic, V Starcevic, D Micic, V Trajkovi. Dual antiglioma action of metformin: cell cycle arrest and mitochondria-dependent apoptosis. Cellular and molecular life sciences : CMLS. vol 64. issue 10. 2007-06-18. PMID:17447005. |
in confluent c6 cultures, on the other hand, metformin caused massive induction of caspase-dependent apoptosis associated with c-jun n-terminal kinase (jnk) activation, mitochondrial depolarization and oxidative stress. |
2007-06-18 |
2023-08-12 |
human |
| Ying-hui Xu, Bin Dong, Qi-zhong Luo, Hong-yu Zhou, Yi-chang Jia, You-feng Yang, Yi-zheng Wan. [Influence of elemene on the expression of Bcl-2 family genes in rat C6 glioma cells]. Zhonghua yi xue za zhi. vol 85. issue 24. 2007-05-29. PMID:16251076. |
to observe the effects of elemene on the induction of apoptosis in rat c6 glioma cells and its influence on expression of bcl-2 family genes. |
2007-05-29 |
2023-08-12 |
rat |
| Wei Zhang, Zhou Fei, Hai-Ning Zhen, Jian-Ning Zhang, Xiang Zhan. Resveratrol inhibits cell growth and induces apoptosis of rat C6 glioma cells. Journal of neuro-oncology. vol 81. issue 3. 2007-04-05. PMID:17031560. |
resveratrol inhibits cell growth and induces apoptosis of rat c6 glioma cells. |
2007-04-05 |
2023-08-12 |
mouse |
| Wei Zhang, Zhou Fei, Hai-Ning Zhen, Jian-Ning Zhang, Xiang Zhan. Resveratrol inhibits cell growth and induces apoptosis of rat C6 glioma cells. Journal of neuro-oncology. vol 81. issue 3. 2007-04-05. PMID:17031560. |
in the present study, we determined the effect of res on the cell growth and apoptosis of rat glioma c6 cell line as well as mouse fibroblast 3t3 cell line, in vitro. |
2007-04-05 |
2023-08-12 |
mouse |
| Jan-Ying Yeh, Bor-Rung Ou, Yu-Chuan Liang, Joel Burchfiel, Judy A Butler, Neil E Forsberg, Philip D Whange. Mechanism for proliferation inhibition by various selenium compounds and selenium-enriched broccoli extract in rat glial cells. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 19. issue 6. 2007-02-26. PMID:16951906. |
c6 rat glial cells were incubated with graded concentrations up to 1000 nm of selenite, selenate, selenomethionine (sem), se-methyl-selenocysteine (semcys), high-se broccoli (h-seb) extract or low-se broccoli (l-seb) extract for 24 and 48 h. mtt results indicated that all se sources and levels examined inhibited c6 cell proliferation at 48 h. the results from cell cycle progression and apoptosis analysis indicated that sem, semcys, h-seb or l-seb treatments at the concentration of 1000 nm reduced the cell population in g(0)/g(1) phase, but induced g(2)/m phase arrest and increased apoptosis and secondary necrosis in c6 cells at 24 h. the populations of apoptotic cells and secondary necrotic cells were increased by all se sources examined. |
2007-02-26 |
2023-08-12 |
rat |
| Yen-Chou Chen, Jyh-Ming Chow, Cheng-Wei Lin, Chin-Yen Wu, Shing-Chuan She. Baicalein inhibition of oxidative-stress-induced apoptosis via modulation of ERKs activation and induction of HO-1 gene expression in rat glioma cells C6. Toxicology and applied pharmacology. vol 216. issue 2. 2006-11-07. PMID:16814338. |
baicalein inhibition of oxidative-stress-induced apoptosis via modulation of erks activation and induction of ho-1 gene expression in rat glioma cells c6. |
2006-11-07 |
2023-08-12 |
rat |
| Vjera Pejanović, Vesna Piperski, Dragana Ugljesić-Kilibarda, Jelena Tasić, Mirjana Dacević, Ljubica Medić-Mijacević, Esmir Gunić, Mirjana Popsavin, Velimir Popsavi. Synthesis and biological activity of some new 5'-O-acyl tiazofurin derivatives. European journal of medicinal chemistry. vol 41. issue 4. 2006-10-20. PMID:16519966. |
three new 5'-o-acyl tiazofurin derivatives 2-4 were synthesized and evaluated for their antiproliferative activity against different tumour cell lines as well as for their ability to induce apoptosis in c6 cells in vitro. |
2006-10-20 |
2023-08-12 |
Not clear |
| Chiung-Huei Peng, Chien-Ning Huang, Shu-Ping Hsu, Chau-Jong Wan. Penta-acetyl geniposide induce apoptosis in C6 glioma cells by modulating the activation of neutral sphingomyelinase-induced p75 nerve growth factor receptor and protein kinase Cdelta pathway. Molecular pharmacology. vol 70. issue 3. 2006-09-28. PMID:16763091. |
penta-acetyl geniposide induce apoptosis in c6 glioma cells by modulating the activation of neutral sphingomyelinase-induced p75 nerve growth factor receptor and protein kinase cdelta pathway. |
2006-09-28 |
2023-08-12 |
Not clear |
| Chee-Fah Chia, Soul-Chin Chen, Chin-Shyang Chen, Chuen-Ming Shih, Horng-Mo Lee, Chih-Hsiung W. Thallium acetate induces C6 glioma cell apoptosis. Annals of the New York Academy of Sciences. vol 1042. 2006-09-11. PMID:15965099. |
thallium acetate induces c6 glioma cell apoptosis. |
2006-09-11 |
2023-08-12 |
Not clear |
| Tríona Ní Chonghaile, Caoimhín G Concannon, Eva Szegezdi, Adrienne M Gorman, Afshin Samal. Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL. Apoptosis : an international journal on programmed cell death. vol 11. issue 7. 2006-09-11. PMID:16699951. |
dexamethasone inhibits apoptosis in c6 glioma cells through increased expression of bcl-xl. |
2006-09-11 |
2023-08-12 |
Not clear |
| Tríona Ní Chonghaile, Caoimhín G Concannon, Eva Szegezdi, Adrienne M Gorman, Afshin Samal. Dexamethasone inhibits apoptosis in C6 glioma cells through increased expression of Bcl-XL. Apoptosis : an international journal on programmed cell death. vol 11. issue 7. 2006-09-11. PMID:16699951. |
we conclude that dex-mediated inhibition of apoptosis in c6 glioma cells is through induction of bcl-x(l). |
2006-09-11 |
2023-08-12 |
Not clear |