| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wim Wätjen, Abdessamab Debbab, Anke Hohlfeld, Yvonni Chovolou, Peter Proksc. The mycotoxin beauvericin induces apoptotic cell death in H4IIE hepatoma cells accompanied by an inhibition of NF-κB-activity and modulation of MAP-kinases. Toxicology letters. vol 231. issue 1. 2015-02-02. PMID:25178661. |
as a molecular mechanism of cell death, necrosis was detected in c6 glioma cells (pi staining), but apoptosis prevails in h4iie hepatoma cells (caspase 3/7 activity, nuclear fragmentation). |
2015-02-02 |
2023-08-13 |
Not clear |
| Xuejun Li, Fei Liu, Zhao Li, Ningrong Ye, Chunhai Huang, Xianrui Yua. Atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma C6 cells. International journal of biological macromolecules. vol 66. 2014-11-24. PMID:24556116. |
atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma c6 cells. |
2014-11-24 |
2023-08-12 |
Not clear |
| Xuejun Li, Fei Liu, Zhao Li, Ningrong Ye, Chunhai Huang, Xianrui Yua. Atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma C6 cells. International journal of biological macromolecules. vol 66. 2014-11-24. PMID:24556116. |
the results demonstrated that amps significantly inhibited proliferation of c6 cells in a concentration dependent manner by dna fragmentation and apoptosis induction. |
2014-11-24 |
2023-08-12 |
Not clear |
| Xuejun Li, Fei Liu, Zhao Li, Ningrong Ye, Chunhai Huang, Xianrui Yua. Atractylodes macrocephala polysaccharides induces mitochondrial-mediated apoptosis in glioma C6 cells. International journal of biological macromolecules. vol 66. 2014-11-24. PMID:24556116. |
these results suggested that the induction of apoptosis via the mitochondrial pathway was involved in the anti-proliferative activity of amps against glioma c6 cells. |
2014-11-24 |
2023-08-12 |
Not clear |
| Xinhui Zhu, Xueping Du, Xiaolong Deng, Hong Yi, Shengyu Cui, Wei Liu, Aiguo Shen, Zhiming Cu. C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. Biochemical and biophysical research communications. vol 452. issue 1. 2014-11-24. PMID:25152399. |
c6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. |
2014-11-24 |
2023-08-13 |
human |
| Xinhui Zhu, Xueping Du, Xiaolong Deng, Hong Yi, Shengyu Cui, Wei Liu, Aiguo Shen, Zhiming Cu. C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. Biochemical and biophysical research communications. vol 452. issue 1. 2014-11-24. PMID:25152399. |
pemetrexed induced moderate apoptosis in os cells, which was dramatically augmented by c6 ceramide. |
2014-11-24 |
2023-08-13 |
human |
| Xinhui Zhu, Xueping Du, Xiaolong Deng, Hong Yi, Shengyu Cui, Wei Liu, Aiguo Shen, Zhiming Cu. C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. Biochemical and biophysical research communications. vol 452. issue 1. 2014-11-24. PMID:25152399. |
the apoptosis inhibitor z-vad-fmk largely inhibited c6 ceramide plus pemetrexed-induced cytotoxicity and apoptosis in os cells. |
2014-11-24 |
2023-08-13 |
human |
| Xinhui Zhu, Xueping Du, Xiaolong Deng, Hong Yi, Shengyu Cui, Wei Liu, Aiguo Shen, Zhiming Cu. C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells. Biochemical and biophysical research communications. vol 452. issue 1. 2014-11-24. PMID:25152399. |
together, we conclude that c6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in os cells probably through in-activation of akt-mtor signaling. |
2014-11-24 |
2023-08-13 |
human |
| Yayuan Liu, Rui Ran, Jiantao Chen, Qifang Kuang, Jie Tang, Ling Mei, Qianyu Zhang, Huile Gao, Zhirong Zhang, Qin H. Paclitaxel loaded liposomes decorated with a multifunctional tandem peptide for glioma targeting. Biomaterials. vol 35. issue 17. 2014-11-17. PMID:24651033. |
when paclitaxel (ptx) was loaded in liposomes, r8-rgd-lipo could induce the strongest inhibition and apoptosis against c6 cells and finally achieved the longest survival in intracranial c6 glioma bearing mice. |
2014-11-17 |
2023-08-12 |
mouse |
| Wei Xu, Maohong Cao, Heyi Zheng, Xiang Tan, Lei Li, Gang Cui, Jian Xu, Jianhua Cao, Kaifu Ke, Qiyun W. Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammation. Journal of neuroscience research. vol 92. issue 3. 2014-09-10. PMID:24301298. |
in vitro studies showed that the upregulation of syf2 might be involved in the activation of c6 cells after lps challenge and the neuronal apoptosis after conditioned media challenge. |
2014-09-10 |
2023-08-12 |
rat |
| Wei Xu, Maohong Cao, Heyi Zheng, Xiang Tan, Lei Li, Gang Cui, Jian Xu, Jianhua Cao, Kaifu Ke, Qiyun W. Upregulation of SYF2 is associated with neuronal apoptosis caused by reactive astrogliosis to neuroinflammation. Journal of neuroscience research. vol 92. issue 3. 2014-09-10. PMID:24301298. |
in addition, with silencing of syf2 in c6 and pc12 cells by sirna, the results indicated that syf2 was required for astrocyte activation and neuronal apoptosis induced by lps. |
2014-09-10 |
2023-08-12 |
rat |
| Jing Xu, Pengjuan Xu, Zhigui Li, Lu Xiao, Zhuo Yan. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cellular & molecular biology letters. vol 18. issue 4. 2014-09-07. PMID:23990403. |
the purpose of this study was to assess whether remifentanil can induce the apoptosis of c6 cells through gsk-3β activation. |
2014-09-07 |
2023-08-12 |
Not clear |
| Jing Xu, Pengjuan Xu, Zhigui Li, Lu Xiao, Zhuo Yan. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cellular & molecular biology letters. vol 18. issue 4. 2014-09-07. PMID:23990403. |
hoechst 33342 staining and flow cytometry showed that remifentanil significantly induced c6 cell apoptosis. |
2014-09-07 |
2023-08-12 |
Not clear |
| Jing Xu, Pengjuan Xu, Zhigui Li, Lu Xiao, Zhuo Yan. The role of glycogen synthase kinase-3β in glioma cell apoptosis induced by remifentanil. Cellular & molecular biology letters. vol 18. issue 4. 2014-09-07. PMID:23990403. |
these results suggest that remifentanil is able to induce c6 cell apoptosis through gsk-3β activation, which provides a basis for its potential use in the treatment of malignant gliomas. |
2014-09-07 |
2023-08-12 |
Not clear |
| Rachana Mishra, Gurcharan Kau. Aqueous ethanolic extract of Tinospora cordifolia as a potential candidate for differentiation based therapy of glioblastomas. PloS one. vol 8. issue 10. 2014-08-07. PMID:24205314. |
on analysis of the cell cycle and apoptotic markers, tce treatment was seen to arrest the c6 cells in g0/g1 and g2/m phase, suppressing expression of g1/s phase specific protein cyclin d1 and anti-apoptotic protein bcl-xl, thus supporting its anti-proliferative and apoptosis inducing potential. |
2014-08-07 |
2023-08-12 |
Not clear |
| Ying Chen, Shih-Hung Yang, Dueng-Yuan Hueng, Jhih-Pu Syu, Chih-Chen Liao, Ya-Chieh W. Cordycepin induces apoptosis of C6 glioma cells through the adenosine 2A receptor-p53-caspase-7-PARP pathway. Chemico-biological interactions. vol 216. 2014-06-24. PMID:24704558. |
cordycepin induces apoptosis of c6 glioma cells through the adenosine 2a receptor-p53-caspase-7-parp pathway. |
2014-06-24 |
2023-08-13 |
rat |
| Ying Chen, Shih-Hung Yang, Dueng-Yuan Hueng, Jhih-Pu Syu, Chih-Chen Liao, Ya-Chieh W. Cordycepin induces apoptosis of C6 glioma cells through the adenosine 2A receptor-p53-caspase-7-PARP pathway. Chemico-biological interactions. vol 216. 2014-06-24. PMID:24704558. |
cordycepin caused apoptosis in c6 glioma cells in a time- and concentration-dependent manner, but did not affect the survival of primary cultured rat astrocytes. |
2014-06-24 |
2023-08-13 |
rat |
| Li-sen Qin, Zheng-quan Yu, Shi-ming Zhang, Guan Sun, Jian Zhu, Jin Xu, Jun Guo, Lin-shan F. The short chain cell-permeable ceramide (C6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells. Molecular biology reports. vol 40. issue 10. 2014-06-07. PMID:24065522. |
the short chain cell-permeable ceramide (c6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells. |
2014-06-07 |
2023-08-12 |
Not clear |
| Li-sen Qin, Zheng-quan Yu, Shi-ming Zhang, Guan Sun, Jian Zhu, Jin Xu, Jun Guo, Lin-shan F. The short chain cell-permeable ceramide (C6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells. Molecular biology reports. vol 40. issue 10. 2014-06-07. PMID:24065522. |
for mechanism study, we observed that ceramide (c6) inhibited autophagy induction to restore cell apoptosis and perifosine sensitivity. |
2014-06-07 |
2023-08-12 |
Not clear |
| Li-sen Qin, Zheng-quan Yu, Shi-ming Zhang, Guan Sun, Jian Zhu, Jin Xu, Jun Guo, Lin-shan F. The short chain cell-permeable ceramide (C6) restores cell apoptosis and perifosine sensitivity in cultured glioblastoma cells. Molecular biology reports. vol 40. issue 10. 2014-06-07. PMID:24065522. |
in conclusion, our study suggests that autophagy inhibition by ceramide (c6) restores perifosine-induced apoptosis and cytotoxicity in glioblastoma cells. |
2014-06-07 |
2023-08-12 |
Not clear |