| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei Du, Hai-Feng Mei, Xue Yin, Yi-Qiao Xin. Delayed growth of glioma by a polysaccharide from Aster tataricus involve upregulation of Bax/Bcl-2 ratio, activation of caspase-3/8/9, and downregulation of the Akt. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 35. issue 3. 2014-06-03. PMID:24081677. |
the results showed that treatment of c6 cells with atp-ii inhibited cell proliferation and this biological response came from induction of dan damage and consequent inducing apoptosis. |
2014-06-03 |
2023-08-12 |
Not clear |
| Jing Xiong, Li Zhou, Yoon Lim, Miao Yang, Yu-Hong Zhu, Zhi-Wei Li, Fiona H Zhou, Zhi-Cheng Xiao, Xin-Fu Zho. Mature BDNF promotes the growth of glioma cells in vitro. Oncology reports. vol 30. issue 6. 2014-05-13. PMID:24064679. |
in the present study using specific mature bdnf antibodies, we found that mature bdnf inhibited c6 glioma cell apoptosis and increased cell growth and migration in vitro. |
2014-05-13 |
2023-08-12 |
Not clear |
| Venkatesh Kota, Vishnu M Dhople, George Fullbright, Nancy M Smythe, Zdzislaw M Szulc, Alicja Bielawska, Hiroko Ham. 2'-hydroxy C16-ceramide induces apoptosis-associated proteomic changes in C6 glioma cells. Journal of proteome research. vol 12. issue 10. 2014-05-06. PMID:23987666. |
upon exposure to (r)-2'-hydroxy-ceramide, c6 glioma cells rapidly underwent apoptosis as indicated by caspase-3 activation, parp cleavage, chromatin condensation, and annexin v stain. |
2014-05-06 |
2023-08-12 |
Not clear |
| Gang Wang, JunJie Wang, Jie Luo, Lei Wang, XuanLi Chen, LiPing Zhang, ShanQing Jian. PEG2000-DPSE-coated quercetin nanoparticles remarkably enhanced anticancer effects through induced programed cell death on C6 glioma cells. Journal of biomedical materials research. Part A. vol 101. issue 11. 2014-04-22. PMID:23529952. |
peg2000-dpse-coated quercetin nanoparticles were prepared and tumor cell killing efficacy was studied on glioma c6 cells and assayed for cell survival, apoptosis, or necrosis. |
2014-04-22 |
2023-08-12 |
Not clear |
| Song Tong, Nanxiang Xiong, Jianying She. RNA interference suppression of Nogo-66 receptor prevents Nogo-66-mediated inhibition of invasion and adhesion and simultaneously increases cell apoptosis in C6 cells. Oncology reports. vol 30. issue 5. 2014-04-07. PMID:23982337. |
we report the impact of nogo-66 and ngr on the proliferation, apoptosis, adhesion and invasion of c6 glioma cells. |
2014-04-07 |
2023-08-12 |
Not clear |
| Song Tong, Nanxiang Xiong, Jianying She. RNA interference suppression of Nogo-66 receptor prevents Nogo-66-mediated inhibition of invasion and adhesion and simultaneously increases cell apoptosis in C6 cells. Oncology reports. vol 30. issue 5. 2014-04-07. PMID:23982337. |
ngr downregulation resulted in a significant increase of c6 adhesion and invasion activity in the presence of nogo-66, markedly inhibited proliferation and induced spontaneous apoptosis. |
2014-04-07 |
2023-08-12 |
Not clear |
| Bo Zhang, Xiyang Sun, Heng Mei, Yu Wang, Ziwei Liao, Jun Chen, Qizhi Zhang, Yu Hu, Zhiqing Pang, Xinguo Jian. LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma. Biomaterials. vol 34. issue 36. 2014-03-25. PMID:24008043. |
dual-targeting effects in an in vitro bbb model showed that peptide-22 decoration on nanoparticles loaded with paclitaxel significantly increased the transport ratio of ptx across the bbb and induced apoptosis of c6 glioma cells below the bbb, and these effects were significantly inhibited by excess free peptide-22. |
2014-03-25 |
2023-08-12 |
mouse |
| Min-Bin Chen, Yan Zhang, Mu-Xin Wei, Wei Shen, Xiao-Yang Wu, Chen Yao, Pei-Hua L. Activation of AMP-activated protein kinase (AMPK) mediates plumbagin-induced apoptosis and growth inhibition in cultured human colon cancer cells. Cellular signalling. vol 25. issue 10. 2014-03-03. PMID:23712032. |
finally, we found that exogenously-added short-chain ceramide (c6) enhances plumbagin-induced ampk activation and facilitates cell apoptosis and growth inhibition. |
2014-03-03 |
2023-08-12 |
human |
| Jian Niu, Chunyang Xing, Chao Yan, Hao Liu, Yuqiong Cui, Haisheng Peng, Yingli Chen, Dianjun Li, Chuanlu Jiang, Nannan Li, Haicheng Yan. Lentivirus-mediated CD/TK fusion gene transfection neural stem cell therapy for C6 glioblastoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:23828263. |
to observe the tumor size and rat survival period in different groups, c6 glioma cell apoptosis and cell viability rate were applied to analyze the tumor inhibition effect of the neural stem cells' transfected cd/tk fusion gene. |
2014-02-21 |
2023-08-12 |
rat |
| Jian Niu, Chunyang Xing, Chao Yan, Hao Liu, Yuqiong Cui, Haisheng Peng, Yingli Chen, Dianjun Li, Chuanlu Jiang, Nannan Li, Haicheng Yan. Lentivirus-mediated CD/TK fusion gene transfection neural stem cell therapy for C6 glioblastoma. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 34. issue 6. 2014-02-21. PMID:23828263. |
c6 cell viability showed that cdglytk-nsc + gcv/5-fc (group 1) was lower than cdglytk-nsc (group 2), nsc + gcv/5-fc (group 3), and control (group 4) from day 2 (p < 0.05), and the apoptosis rate was higher in group 1 compared with that of other groups (50.6%, p < 0.05) either in vitro or in vivo (35.47%, p < 0.05); both cell viability and apoptosis had no significance in the other three groups. |
2014-02-21 |
2023-08-12 |
rat |
| Gokhan Kus, Pinar Oztopcu-Vatan, Ruhi Uyar, Selda Kabader. Cytotoxic and apoptotic functions of licofelone on rat glioma cells. Acta biologica Hungarica. vol 64. issue 4. 2014-01-17. PMID:24275590. |
using colchicine and 5-fluorouracil as positive controls, we questioned whether licofelone affects the survival of rat glioma cell line (c6) and induces apoptosis in vitro. |
2014-01-17 |
2023-08-12 |
rat |
| Gokhan Kus, Pinar Oztopcu-Vatan, Ruhi Uyar, Selda Kabader. Cytotoxic and apoptotic functions of licofelone on rat glioma cells. Acta biologica Hungarica. vol 64. issue 4. 2014-01-17. PMID:24275590. |
comparing to the control, treatments with 10, 50 and 100 μm licofelone for 24 or 48 h did not influence c6 survival, however, 150, 200 and 250 μm licofelone reduced the number of living cells by 58, 88 and 93%, respectively, and induced apoptosis of c6 cells in a dose and time dependent manner. |
2014-01-17 |
2023-08-12 |
rat |
| Hai-zhong Huo, Bing Wang, Jian Qin, Shan-yu Guo, Wen-yong Liu, Yan G. AMP-activated protein kinase (AMPK)/Ulk1-dependent autophagic pathway contributes to C6 ceramide-induced cytotoxic effects in cultured colorectal cancer HT-29 cells. Molecular and cellular biochemistry. vol 378. issue 1-2. 2013-11-04. PMID:23508272. |
however, no significant apoptosis was observed in c6 ceramide-treated ht-29 cells. |
2013-11-04 |
2023-08-12 |
Not clear |
| Hai-zhong Huo, Bing Wang, Jian Qin, Shan-yu Guo, Wen-yong Liu, Yan G. AMP-activated protein kinase (AMPK)/Ulk1-dependent autophagic pathway contributes to C6 ceramide-induced cytotoxic effects in cultured colorectal cancer HT-29 cells. Molecular and cellular biochemistry. vol 378. issue 1-2. 2013-11-04. PMID:23508272. |
our results suggest that autophagy, but not apoptosis, is a major contributor for c6 ceramide-induced cytotoxic effects in ht-29 cells, and activation of ampk/ulk1 is required for the process. |
2013-11-04 |
2023-08-12 |
Not clear |
| Jianrong Lu, Feng Zhang, Yong Yuan, Caixia Ding, Liying Zhang, Qing L. All-trans retinoic acid upregulates the expression of p53 via Axin and inhibits the proliferation of glioma cells. Oncology reports. vol 29. issue 6. 2013-10-29. PMID:23588680. |
in addition, ectopic expression of axin by transient transfection of c6 cells with raxin revealed that overexpression of axin induced cell cycle arrest and apoptosis with an upregulation of p53. |
2013-10-29 |
2023-08-12 |
Not clear |
| Yan Li, Ning Xu, Lei Cai, Zijun Gao, Lan Shen, Qiaomei Zhang, Wugang Hou, Haixing Zhong, Qiang Wang, Lize Xion. NDRG2 is a novel p53-associated regulator of apoptosis in C6-originated astrocytes exposed to oxygen-glucose deprivation. PloS one. vol 8. issue 2. 2013-09-27. PMID:23451161. |
in this study, we investigated the role of ndrg2 in cellular apoptosis induced by oxygen-glucose deprivation (ogd) in il-6-differentiated c6 glioma cells. |
2013-09-27 |
2023-08-12 |
Not clear |
| Ye Xu, Jinsong Kang, Zhaoxin Yuan, Hongyan Li, Jing Su, Yang Li, Xiaoxia Kong, Hongyu Zhang, Weiwei Wang, Liankun Su. Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23380911. |
suppression of clic4/mtclic enhances hydrogen peroxide-induced apoptosis in c6 glioma cells. |
2013-09-12 |
2023-08-12 |
Not clear |
| Ye Xu, Jinsong Kang, Zhaoxin Yuan, Hongyan Li, Jing Su, Yang Li, Xiaoxia Kong, Hongyu Zhang, Weiwei Wang, Liankun Su. Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23380911. |
in this study, we showed the important role of clic4 in apoptosis of c6 glioma cells induced by hydrogen peroxide (h2o2). |
2013-09-12 |
2023-08-12 |
Not clear |
| Ye Xu, Jinsong Kang, Zhaoxin Yuan, Hongyan Li, Jing Su, Yang Li, Xiaoxia Kong, Hongyu Zhang, Weiwei Wang, Liankun Su. Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23380911. |
our results showed that clic4 protein expression was upregulated following h2o2-induced c6 cell apoptosis. |
2013-09-12 |
2023-08-12 |
Not clear |
| Ye Xu, Jinsong Kang, Zhaoxin Yuan, Hongyan Li, Jing Su, Yang Li, Xiaoxia Kong, Hongyu Zhang, Weiwei Wang, Liankun Su. Suppression of CLIC4/mtCLIC enhances hydrogen peroxide-induced apoptosis in C6 glioma cells. Oncology reports. vol 29. issue 4. 2013-09-12. PMID:23380911. |
the upregulation of clic4 protein expression was paralleled with an increased bax/bcl-2 ratio, cytochrome c and cleaved caspase-3 protein expression upon h2o2-induced c6 cell apoptosis. |
2013-09-12 |
2023-08-12 |
Not clear |