| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Susanne Schiffmann, Thorsten Jürgen Maier, Ivonne Wobst, Astrid Janssen, Heike Corban-Wilhelm, Carlo Angioni, Gerd Geisslinger, Sabine Grösc. The anti-proliferative potency of celecoxib is not a class effect of coxibs. Biochemical pharmacology. vol 76. issue 2. 2008-07-31. PMID:18547544. |
apoptosis and cell cycle arrest were determined using flow cytometric and western blot analysis. |
2008-07-31 |
2023-08-12 |
mouse |
| Wei Zhou, Xu Zhu, Liang Zhu, Yong Yao Cui, Hao Wang, Hong Qi, Qiu Shi Ren, Hong Zhuan Che. Neuroprotection of muscarinic receptor agonist pilocarpine against glutamate-induced apoptosis in retinal neurons. Cellular and molecular neurobiology. vol 28. issue 2. 2008-07-30. PMID:18172757. |
in rat primary retinal cultures, identification of neuron, cell viability, apoptosis, intracellular ca(2+) concentration, mitochondrial membrane potential, gene expression were studied by immunofluorescence, mtt, high content scanning, confocal microscopy, reverse-transcription pcr, and western blot analysis, respectively. |
2008-07-30 |
2023-08-12 |
rat |
| Sin Ting Lau, Zhi-Xiu Lin, Ming Zhao, Po Sing Leun. Brucea javanica fruit induces cytotoxicity and apoptosis in pancreatic adenocarcinoma cell lines. Phytotherapy research : PTR. vol 22. issue 4. 2008-07-29. PMID:18386257. |
western blot analysis further showed down-regulation of pro-caspase 3 protein expression, indicating that the observed cytotoxic effects of the extract were associated with induction of apoptosis. |
2008-07-29 |
2023-08-12 |
human |
| Viktor R Drel, Pal Pacher, Tayyeba K Ali, Jeho Shin, Ulrich Julius, Azza B El-Remessy, Irina G Obrosov. Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis. International journal of molecular medicine. vol 21. issue 6. 2008-07-23. PMID:18506358. |
apoptosis was assessed by tunel assay, nitrotyrosine and poly(adp-ribose) by immunocytochemistry, and bax and bcl-2 expression by western blot analyses. |
2008-07-23 |
2023-08-12 |
rat |
| b' Martina Rez\\xc3\\xa1cov\\xc3\\xa1, Ales Tich\\xc3\\xbd, Jirina V\\xc3\\xa1vrov\\xc3\\xa1, Doris Vokurkov\\xc3\\xa1, Em\\xc3\\xadlie Luk\\xc3\\xa1sov\\xc3\\xa. Is defect in phosphorylation of Nbs1 responsible for high radiosensitivity of T-lymphocyte leukemia cells MOLT-4? Leukemia research. vol 32. issue 8. 2008-07-15. PMID:18262646.' |
western blot method revealed massive phosphorylation of h2a.x during apoptosis induction, 6-24 h after irradiation by the doses 1.5 and 3 gy. |
2008-07-15 |
2023-08-12 |
Not clear |
| Qiang Zhang, Xin-Huai Zhao, Zhu-Jun Wan. Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 46. issue 6. 2008-07-10. PMID:18331776. |
furthermore, the expression of genes related to cell cycle arrest and apoptosis was assessed by oligonucleotide microarray, real-time rt-pcr and western blot. |
2008-07-10 |
2023-08-12 |
human |
| Adnan O Abu-Yousif, Kimberly A Smith, Spiro Getsios, Kathleen J Green, Rukiyah T Van Dross, Jill C Pellin. Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures. Cancer research. vol 68. issue 8. 2008-06-10. PMID:18413777. |
each keratinocyte model was exposed to a moderate dose of uvb (300-1,000 j/m(2)), then treated with apigenin (0-50 micromol/l), and harvested to assess apoptosis by western blot analysis for poly(adp)ribose polymerase cleavage, annexin-v staining by flow cytometry, and/or the presence of sunburn cells. |
2008-06-10 |
2023-08-12 |
mouse |
| Minghao Fang, Xuemei Ji, Yi Tang, Wenli Li. P53 regulation of leukemia cells with the blockage of MDM2 by antisense oligonucleotides. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 26. issue 4. 2008-06-06. PMID:17120736. |
fcm analysis and western blot and rt-pcr were used to estimate apoptosis and the expression of mdm2 and p53. |
2008-06-06 |
2023-08-12 |
Not clear |
| J-Y Kim, S-K Kwok, K-H Hur, H-J Kim, N S Kim, S-A Yoo, W-U Kim, C-S Ch. Up-regulated macrophage migration inhibitory factor protects apoptosis of dermal fibroblasts in patients with systemic sclerosis. Clinical and experimental immunology. vol 152. issue 2. 2008-06-04. PMID:18355352. |
the degree of apoptosis was determined by colorimetric assay, and signalling pathways were examined by western blot. |
2008-06-04 |
2023-08-12 |
Not clear |
| Guanghui Liu, Yingying Sun, Zhenhua Li, Tao Song, Haibin Wang, Yun Zhang, Zhiming G. Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease. Biochemical and biophysical research communications. vol 370. issue 4. 2008-05-30. PMID:18420027. |
we performed immunohistochemistry, western blot, and real-time pcr to analyze indicators of er molecule chaperone and er-associated apoptosis. |
2008-05-30 |
2023-08-12 |
rat |
| Fréderic Lirussi, Zo Rakotoniaina, Siham Madani, Françoise Goirand, Michelle Breuiller-Fouché, Marie-Josèphe Leroy, Paul Sagot, John J Morrison, Monique Dumas, Marc Bardo. ADRB3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis. Biology of reproduction. vol 78. issue 3. 2008-05-22. PMID:17989355. |
to explore the cellular consequences of chorioamnionitis and detect apoptosis, we first performed immunostaining and western blot experiments on human myometrial samples obtained from women with confirmed chorioamnionitis. |
2008-05-22 |
2023-08-12 |
human |
| Yan-Qiu Shi, Yong-Xiang Liao, Xian-Jun Qu, Hui-Qing Yuan, Song Li, Jian-Bo Qu, Hong-Xiang Lo. Marchantin C, a macrocyclic bisbibenzyl, induces apoptosis of human glioma A172 cells. Cancer letters. vol 262. issue 2. 2008-05-13. PMID:18215458. |
rt-pcr and western blot assay further substantiated that marchantin c, as a promising pro-apoptotic agent, had strong effects to induce a172 cell apoptosis, suggesting that the action was achieved through up-regulating bax and down-regulating bcl-2. |
2008-05-13 |
2023-08-12 |
human |
| Norifumi Sawada, Jian Yao, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Isao Araki, Masayuki Takeda, Masanori Kitamur. Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder. Laboratory investigation; a journal of technical methods and pathology. vol 88. issue 5. 2008-05-08. PMID:18347581. |
an experimental model of boo was established in rats by complete ligature of the urethra for 24 h, and bladders were subjected to northern blot analysis and assessment of apoptosis. |
2008-05-08 |
2023-08-12 |
rat |
| L Chu, J Gu, L Sun, Q Qian, C Qian, X Li. Oncolytic adenovirus-mediated shRNA against Apollon inhibits tumor cell growth and enhances antitumor effect of 5-fluorouracil. Gene therapy. vol 15. issue 7. 2008-05-02. PMID:18239605. |
cell cycle analysis, 4',6-diamidino-2-phenylindole staining and western blot analysis reveal that zd55-siapollon-mediated suppression of apollon induces apoptosis. |
2008-05-02 |
2023-08-12 |
mouse |
| Sanjica Jakopec, Dalibor Karlović, Klara Dubravcić, Drago Batinić, Jasna Sorić, Anamaria Brozović, Danijel Buljan, Maja Osma. Lithium effect on glutamate induced damage in glioblastoma cells. Collegium antropologicum. vol 32 Suppl 1. 2008-05-01. PMID:18405064. |
cytotoxicity of glutamate was examined by spectrophotometric mtt assay, while the expression of apoptosis related genes was examined by western blot method. |
2008-05-01 |
2023-08-12 |
human |
| Lei Qiang, Yong Yang, Qi-Dong You, Yan-Jun Ma, Lan Yang, Fei-Fei Nie, Hong-Yan Gu, Li Zhao, Na Lu, Qi Qi, Wei Liu, Xiao-Tang Wang, Qing-Long Gu. Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study. Biochemical pharmacology. vol 75. issue 5. 2008-04-25. PMID:18070617. |
to reveal an involvement of the intrinsic mitochondrial pathway of apoptosis, the mitochondrial membrane potential and the western blot evaluation of bax, bcl-2, caspase-3, caspase-9 and cytochrome c released from mitochondria were performed. |
2008-04-25 |
2023-08-12 |
rat |
| Y B Ji, S Y Gao, C F Ji, X Zo. Induction of apoptosis in HepG2 cells by solanine and Bcl-2 protein. Journal of ethnopharmacology. vol 115. issue 2. 2008-04-22. PMID:18022776. |
the effect on the morphology was observed with a laser confocal microscopy; the rate of apoptosis and the cell cycle were measured using flow cytometry (fcm); the expression of bcl-2 protein was measured by western blot. |
2008-04-22 |
2023-08-12 |
Not clear |
| W Y Lam, Julian W Tang, Apple C M Yeung, Lawrence C M Chiu, Joseph J Y Sung, Paul K S Cha. Avian influenza virus A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells. Journal of virology. vol 82. issue 6. 2008-03-31. PMID:18199656. |
western blot analyses also showed that there was prominent cleavage of poly(adp-ribose) polymerase and activation of caspase-3, caspase-7, and caspase-8 during the ns1-induced apoptosis. |
2008-03-31 |
2023-08-12 |
human |
| Sumit Bhattacharyya, Alip Borthakur, Pradeep K Dudeja, Joanne K Tobacma. Carrageenan induces cell cycle arrest in human intestinal epithelial cells in vitro. The Journal of nutrition. vol 138. issue 3. 2008-03-21. PMID:18287351. |
additional data, including dna ladder, poly adp ribose polymerase western blot, nuclear dna staining, and activities of caspases 3 and 7, indicated no evidence of increased apoptosis following cgn exposure and were consistent with cgn-induced necrotic cell death. |
2008-03-21 |
2023-08-12 |
human |
| Jae Myung Park, Takashi Kakimoto, Tsukasa Kuroki, Ryosuke Shiraishi, Takehiro Fujise, Ryuichi Iwakiri, Kazuma Fujimot. Suppression of intestinal mucosal apoptosis by ghrelin in fasting rats. Experimental biology and medicine (Maywood, N.J.). vol 233. issue 1. 2008-03-17. PMID:18156305. |
intestinal mucosal apoptosis was evaluated as the percentage of fragmented dna, villus height, and terminal deoxynucleotidyl transferase-mediated dudp-biotin nick end-labeling (tunel) staining and by western blot analysis of caspase-3 in 48-hr fasting rats. |
2008-03-17 |
2023-08-12 |
rat |