| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ruixia Wang, Weili Zhan. Isoliquiritigenin regulates microglial M1/M2 polarisation by mediating the P38/MAPK pathway in cerebral stroke. The Journal of pharmacy and pharmacology. 2023-04-07. PMID:37027320. |
regulation of microglia polarisation may be a new way to treat ischaemic stroke based on its effects on brain injury. |
2023-04-07 |
2023-08-14 |
Not clear |
| Ze Wang, Yaying Song, Shuwei Bai, Weiwei Xiang, Xiajun Zhou, Lu Han, Desheng Zhu, Yangtai Gua. Imaging of microglia in post-stroke inflammation. Nuclear medicine and biology. vol 118-119. 2023-04-07. PMID:37028196. |
our review discusses alternative biological targets that have attracted considerable interest for the imaging of microglia activation in recent years, and the potential value of imaging of microglia in the assessment of stroke therapies. |
2023-04-07 |
2023-08-14 |
Not clear |
| Chenye Qiao, Zongjian Liu, Shuyan Qi. The Implications of Microglial Regulation in Neuroplasticity-Dependent Stroke Recovery. Biomolecules. vol 13. issue 3. 2023-03-29. PMID:36979506. |
we have previously shown that the development of neuroplasticity is spatiotemporally consistent with microglial activation, suggesting that microglia may have a profound impact on neuroplasticity after stroke and may be a key therapeutic target for post-stroke rehabilitation. |
2023-03-29 |
2023-08-14 |
Not clear |
| Ricardo Jair Ramírez-Carreto, Yesica María Rodríguez-Cortés, Haydee Torres-Guerrero, Anahí Chavarrí. Possible Implications of Obesity-Primed Microglia that Could Contribute to Stroke-Associated Damage. Cellular and molecular neurobiology. 2023-03-20. PMID:36935429. |
understanding how microglia react in various microenvironments, such as chronic inflammation, made it possible to establish therapeutic windows and identify synergic interactions with acute damage events like stroke. |
2023-03-20 |
2023-08-14 |
human |
| Rui Liu, Ying Li, Ziyue Wang, Peng Chen, Yi Xie, Wensheng Qu, Minghuan Wang, Zhiyuan Yu, Xiang Lu. Regulatory T cells promote functional recovery after spinal cord injury by alleviating microglia inflammation via STAT3 inhibition. CNS neuroscience & therapeutics. 2023-03-14. PMID:36914969. |
previous studies have reported that regulatory t cells (tregs) enter the central nervous system and exert immunosuppressive effects on microglia during multiple sclerosis and stroke. |
2023-03-14 |
2023-08-14 |
Not clear |
| Hongyan Liao, Jiagui Huang, Jie Liu, Yue Chen, Huimin Zhu, Xuemei Li, Jun Wen, Qin Xiang, Qin Yan. Resveratrol Inhibits Activation of Microglia after Stroke through Triggering Translocation of Smo to Primary Cilia. Journal of personalized medicine. vol 13. issue 2. 2023-02-25. PMID:36836502. |
resveratrol inhibits activation of microglia after stroke through triggering translocation of smo to primary cilia. |
2023-02-25 |
2023-08-14 |
mouse |
| Hongyan Liao, Jiagui Huang, Jie Liu, Yue Chen, Huimin Zhu, Xuemei Li, Jun Wen, Qin Xiang, Qin Yan. Resveratrol Inhibits Activation of Microglia after Stroke through Triggering Translocation of Smo to Primary Cilia. Journal of personalized medicine. vol 13. issue 2. 2023-02-25. PMID:36836502. |
activated microglia act as a double-edged sword for stroke. |
2023-02-25 |
2023-08-14 |
mouse |
| Hongyan Liao, Jiagui Huang, Jie Liu, Yue Chen, Huimin Zhu, Xuemei Li, Jun Wen, Qin Xiang, Qin Yan. Resveratrol Inhibits Activation of Microglia after Stroke through Triggering Translocation of Smo to Primary Cilia. Journal of personalized medicine. vol 13. issue 2. 2023-02-25. PMID:36836502. |
therefore, it is of great clinical transforming potential to explore drugs or methods that can inhibit abnormal activation of microglia in the acute phase of stroke to improve neurological function after stroke. |
2023-02-25 |
2023-08-14 |
mouse |
| Victoria G Hernandez, Kendra J Lechtenberg, Todd C Peterson, Li Zhu, Tawaun A Lucas, Justice O Owah, Alanna I Dorsey, Andrew J Gentles, Marion S Buckwalte. Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke. bioRxiv : the preprint server for biology. 2023-02-24. PMID:36824949. |
translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke. |
2023-02-24 |
2023-08-14 |
Not clear |
| Victoria G Hernandez, Kendra J Lechtenberg, Todd C Peterson, Li Zhu, Tawaun A Lucas, Justice O Owah, Alanna I Dorsey, Andrew J Gentles, Marion S Buckwalte. Translatome analysis reveals microglia and astrocytes to be distinct regulators of inflammation in the hyperacute and acute phases after stroke. bioRxiv : the preprint server for biology. 2023-02-24. PMID:36824949. |
microglia initiated a rapid response to stroke at 4 hours by adopting an inflammatory profile associated with the recruitment of immune cells. |
2023-02-24 |
2023-08-14 |
Not clear |
| Junqiu Jia, Lili Zheng, Lei Ye, Jian Chen, Shu Shu, Siyi Xu, Xinyu Bao, Shengnan Xia, Renyuan Liu, Yun Xu, Meijuan Zhan. CD11c Cell death & disease. vol 14. issue 2. 2023-02-24. PMID:36828819. |
additionally, the precise molecular communications between microglia and white matter repair during the stroke rehabilitation phase remain elusive. |
2023-02-24 |
2023-08-14 |
mouse |
| Junqiu Jia, Lili Zheng, Lei Ye, Jian Chen, Shu Shu, Siyi Xu, Xinyu Bao, Shengnan Xia, Renyuan Liu, Yun Xu, Meijuan Zhan. CD11c Cell death & disease. vol 14. issue 2. 2023-02-24. PMID:36828819. |
in this current study, mri dti scan and immunofluorescence staining were performed to trace white matter and microglia in the mouse transient middle cerebral artery occlusion (tmcao) stroke model. |
2023-02-24 |
2023-08-14 |
mouse |
| Sanna H Loppi, Marco A Tavera-Garcia, Danielle A Becktel, Boaz K Maiyo, Kristos E Johnson, Thuy-Vi V Nguyen, Rick G Schnellmann, Kristian P Doyl. Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023-02-11. PMID:36772984. |
increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke. |
2023-02-11 |
2023-08-14 |
mouse |
| Sanna H Loppi, Marco A Tavera-Garcia, Danielle A Becktel, Boaz K Maiyo, Kristos E Johnson, Thuy-Vi V Nguyen, Rick G Schnellmann, Kristian P Doyl. Increased fatty acid metabolism and decreased glycolysis are hallmarks of metabolic reprogramming within microglia in degenerating white matter during recovery from experimental stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2023-02-11. PMID:36772984. |
these results indicate that chronic metabolic differences exist between stroked and control brains, including alterations in fatty acid metabolism and glycolysis within microglia in areas of degenerating white matter for at least 12 weeks after stroke. |
2023-02-11 |
2023-08-14 |
mouse |
| Komal Thapa, Kumar Shivam, Heena Khan, Amarjot Kaur, Kamal Dua, Sachin Singh, Thakur Gurjeet Sing. Emerging Targets for Modulation of Immune Response and Inflammation in Stroke. Neurochemical research. 2023-02-10. PMID:36763312. |
the innate immune activation stimulated by microglia during stroke results in the migration of macrophages and lymphocytes into the brain and are responsible for tissue damage. |
2023-02-10 |
2023-08-14 |
Not clear |
| A D Roseborough, S J Myers, R Khazaee, Y Zhu, L Zhao, E Iorio, F M Elahi, S H Pasternak, S N Whitehea. Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model. Journal of neuroinflammation. vol 20. issue 1. 2023-02-01. PMID:36721258. |
plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model. |
2023-02-01 |
2023-08-14 |
Not clear |
| A D Roseborough, S J Myers, R Khazaee, Y Zhu, L Zhao, E Iorio, F M Elahi, S H Pasternak, S N Whitehea. Plasma derived extracellular vesicle biomarkers of microglia activation in an experimental stroke model. Journal of neuroinflammation. vol 20. issue 1. 2023-02-01. PMID:36721258. |
the aim of this study was to identify activation-state specific microglia evs (mevs) in vitro followed by validation in an experimental stroke model. |
2023-02-01 |
2023-08-14 |
Not clear |
| Hongyan Liao, Jiagui Huang, Jie Liu, Huimin Zhu, Yue Chen, Xuemei Li, Jun Wen, Qin Yan. Sirt1 regulates microglial activation and inflammation following oxygen-glucose deprivation/reoxygenation injury by targeting the Shh/Gli-1 signaling pathway. Molecular biology reports. 2023-02-01. PMID:36725745. |
cerebral ischemic injury leads to over-activation of microglia, which release pro-inflammatory factors that deteriorate neurological function during the acute phase of stroke. |
2023-02-01 |
2023-08-14 |
Not clear |
| Vivianne E Morrison, Gregory J Bi. The meal Maketh the Microglia: Why studying microglial phagocytosis is critical to stroke research. Neurochemistry international. 2023-01-27. PMID:36707032. |
the meal maketh the microglia: why studying microglial phagocytosis is critical to stroke research. |
2023-01-27 |
2023-08-14 |
Not clear |
| Seung Gyu Choi, Juhee Shin, Ka Young Lee, Hyewon Park, Song I Kim, Yoon Young Yi, Dong Woon Kim, Hee-Jung Song, Hyo Jung Shi. PINK1 siRNA-loaded poly(lactic-co-glycolic acid) nanoparticles provide neuroprotection in a mouse model of photothrombosis-induced ischemic stroke. Glia. 2023-01-19. PMID:36655313. |
application of nanoparticles for pink1 inhibition attenuates rb-induced photothrombotic ischemic injury by inhibiting microglia responses, suggesting that a nanomedical approach targeting the pink1 pathway may provide a therapeutic avenue for stroke treatment. |
2023-01-19 |
2023-08-14 |
mouse |