| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huiya Li, Pinyi Liu, Bing Zhang, Zengqiang Yuan, Mengdi Guo, Xinxin Zou, Yi Qian, Shiji Deng, Liwen Zhu, Xiang Cao, Tao Tao, Shengnan Xia, Xinyu Bao, Yun X. Acute ischemia induces spatially and transcriptionally distinct microglial subclusters. Genome medicine. vol 15. issue 1. 2023-12-12. PMID:38082331. |
microglia immediately respond to ischemic insult and initiate immune inflammation, playing an important role in the cellular injury after stroke. |
2023-12-12 |
2023-12-17 |
Not clear |
| Xin Gao, Gang Su, Miao Chai, Minghui Shen, Zhenzhen Hu, Wei Chen, Juan Gao, Ruixin Li, Tianfei Ma, Yang An, Zhenchang Zhan. Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia. Neurochemistry international. 2023-12-11. PMID:38081419. |
activated microglia participate in the pathological processes after stroke through polarization, autophagy, phagocytosis, pyroptosis, ferroptosis, apoptosis, and necrosis, thereby influencing the injury and repair following stroke. |
2023-12-11 |
2023-12-17 |
Not clear |
| Xin Gao, Gang Su, Miao Chai, Minghui Shen, Zhenzhen Hu, Wei Chen, Juan Gao, Ruixin Li, Tianfei Ma, Yang An, Zhenchang Zhan. Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia. Neurochemistry international. 2023-12-11. PMID:38081419. |
autophagy and phagocytosis in microglia following ischemia are dynamic processes, where moderate levels promote cell survival, while excessive responses may exacerbate neurofunctional deficits following stroke. |
2023-12-11 |
2023-12-17 |
Not clear |
| Jingwei Song, Syed Aqib Ali Zaidi, Liangge He, Shuai Zhang, Guangqian Zho. Integrative Analysis of Machine Learning and Molecule Docking Simulations for Ischemic Stroke Diagnosis and Therapy. Molecules (Basel, Switzerland). vol 28. issue 23. 2023-12-09. PMID:38067435. |
the rna velocity and pseudo time analysis showed that microglia subcluster 0 would develop toward subcluster 2 within 24 h from stroke onset. |
2023-12-09 |
2023-12-17 |
Not clear |
| Jingwei Song, Syed Aqib Ali Zaidi, Liangge He, Shuai Zhang, Guangqian Zho. Integrative Analysis of Machine Learning and Molecule Docking Simulations for Ischemic Stroke Diagnosis and Therapy. Molecules (Basel, Switzerland). vol 28. issue 23. 2023-12-09. PMID:38067435. |
az_628, which screened from cmap analysis, was found to have lower binding energy with mmp12, lgals3, fam20c, capg, pkm2, sdc4, and itga5 in microglia subcluster 2 and maybe a therapeutic agent for the poor development of microglia subcluster 2 after stroke. |
2023-12-09 |
2023-12-17 |
Not clear |
| Lu Yu, Zuohui Zhang, Hao Chen, Miao Wang, Wenqi Mao, Jinxia Hu, Dandan Zuo, Bingchen Lv, Weifeng Wu, Suhua Qi, Guiyun Cu. Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke. Bioengineering & translational medicine. vol 8. issue 6. 2023-12-01. PMID:38023701. |
remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating hgf after acute ischemia stroke. |
2023-12-01 |
2023-12-07 |
mouse |
| Lu Yu, Zuohui Zhang, Hao Chen, Miao Wang, Wenqi Mao, Jinxia Hu, Dandan Zuo, Bingchen Lv, Weifeng Wu, Suhua Qi, Guiyun Cu. Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke. Bioengineering & translational medicine. vol 8. issue 6. 2023-12-01. PMID:38023701. |
remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating hgf after acute ischemia stroke. |
2023-11-29 |
2023-12-07 |
mouse |
| Weizhuo Lu, Zhiwu Chen, Jiyue We. Flavonoids and ischemic stroke-induced neuroinflammation: Focus on the glial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-11-28. PMID:38016362. |
after stroke onset, microglia, astrocytes and the infiltrating immune cells contribute to a complicated neuroinflammation cascade and play the complicated roles in the pathophysiological variations of ischemic stroke. |
2023-11-28 |
2023-12-07 |
Not clear |
| Nikolett Lénárt, Csaba Cserép, Eszter Császár, Balázs Pósfai, Ádám Déne. Microglia-neuron-vascular interactions in ischemia. Glia. 2023-11-15. PMID:37964690. |
while the contribution of non-neuronal cells to stroke pathophysiology is increasingly recognized, recent data show that microglia, the main immune cells of the central nervous system parenchyma, play previously unrecognized roles in basic physiological processes beyond their inflammatory functions, which markedly change during ischemic conditions. |
2023-11-15 |
2023-11-20 |
Not clear |
| Miguel M Lino, Tiago Rondão, Arnab Banerjee, Inês Aires, Magda Rodrigues, Tiago Reis, António Santinha, Dominique Fernandes, Débora Serrenho, Tomás Sobrino, João Sargento-Freitas, Frederico C Pereira, Ana Luísa Carvalho, Lino Ferreir. Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. Nanoscale. 2023-11-07. PMID:37933179. |
small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. |
2023-11-07 |
2023-11-08 |
mouse |
| Kimberly Prescott, Alexandra E Münch, Evan Brahms, Maya M Weigel, Kenya Inoue, Marion S Buckwalter, Shane A Liddelow, Todd C Peterso. Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke. bioRxiv : the preprint server for biology. 2023-10-31. PMID:37905154. |
microglia and astrocytes play an important role in the neuroinflammatory response and contribute to both the destruction of neighboring tissue as well as the resolution of inflammation following stroke. |
2023-10-31 |
2023-11-08 |
Not clear |
| Fatemehsadat Seyedaghamiri, Mohammad Hossein Geranmayeh, Tahereh Ghadiri, Abbas Ebrahimi-Kalan, Leila Hossein. A new insight into the role of pericytes in ischemic stroke. Acta neurologica Belgica. 2023-10-07. PMID:37805645. |
microglia regulate immunity and inflammatory response after stroke. |
2023-10-07 |
2023-10-15 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
changes in microglia during drug treatment of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
microglia play a complex role in the process of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
therefore, we talk about the pathophysiological mechanisms of stroke and elaborate on the microglia signaling pathways of drug action in stroke models and how these drugs play a role in stroke treatment in this review. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
understanding how drugs modulate proinflammatory and anti-inflammatory responses of microglia may be critical to implementing therapeutic strategies using immune interventions in stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| S J Myers, Agapova, S V Patel, S H Hayes, L A Sposato, B L Allman, S N Whitehea. Acute minocycline treatment inhibits microglia activation, reduces infarct volume, and has domain-specific effects on post-ischemic stroke cognition in rats. Behavioural brain research. 2023-09-24. PMID:37742808. |
acute minocycline treatment inhibits microglia activation, reduces infarct volume, and has domain-specific effects on post-ischemic stroke cognition in rats. |
2023-09-24 |
2023-10-07 |
rat |
| George Fadoul, Milos Ikonomovic, Feng Zhang, Tuo Yan. The cell-specific roles of Nrf2 in acute and chronic phases of ischemic stroke. CNS neuroscience & therapeutics. 2023-09-16. PMID:37715557. |
in this review, we comprehensively summarize the protective effects of nrf2 in experimental ischemic stroke, emphasizing the role of nrf2 in different cell types including neurons, astrocytes, oligodendrocytes, microglia, and endothelial cells during acute and chronic phases of stroke and providing insights on the neuroprotective role of nrf2 on each cell type throughout the long term of stroke care. |
2023-09-16 |
2023-10-07 |
Not clear |
| Matteo Haupt, Stefan T Gerner, Hagen B Huttner, Thorsten R Doeppne. Preconditioning Concepts for the Therapeutic Use of Extracellular Vesicles Against Stroke. Stem cells translational medicine. 2023-09-11. PMID:37696005. |
various preclinical stroke models have demonstrated the neuroprotective effects of extracellular vesicles (evs) obtained from several types of cells, including neurons, astrocytes, microglia, neuronal progenitor cells, bone marrow stem cells, and mesenchymal stem cells. |
2023-09-11 |
2023-10-07 |
Not clear |
| Chikage Kijima, Toshiki Inaba, Kenichiro Hira, Nobukazu Miyamoto, Kazuo Yamashiro, Takao Urabe, Nobutaka Hattori, Yuji Uen. Astrocytic Extracellular Vesicles Regulated by Microglial Inflammatory Responses Improve Stroke Recovery. Molecular neurobiology. 2023-09-07. PMID:37676390. |
we investigated whether astrocytic extracellular vesicles (aevs) regulated by microglia modulate glial scars and improve stroke recovery. |
2023-09-07 |
2023-10-07 |
Not clear |