| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yiwei Feng, Lishan Lin, Tengteng Wu, Yukun Feng, Fengyin Liang, Ge Li, Yongchao Li, Yalun Guan, Shuhua Liu, Yu Zhang, Guangqing Xu, Zhong Pe. Cortical microinfarcts potentiate recurrent ischemic injury through NLRP3-dependent trained immunity. Cell death & disease. vol 15. issue 1. 2024-01-12. PMID:38216560. |
the results showed that microinfarcts led to trained immunity in microglia, which worsened the pro-inflammatory response and ischemic injury in the secondary photothrombotic stroke. |
2024-01-12 |
2024-01-15 |
Not clear |
| Yiwei Feng, Lishan Lin, Tengteng Wu, Yukun Feng, Fengyin Liang, Ge Li, Yongchao Li, Yalun Guan, Shuhua Liu, Yu Zhang, Guangqing Xu, Zhong Pe. Cortical microinfarcts potentiate recurrent ischemic injury through NLRP3-dependent trained immunity. Cell death & disease. vol 15. issue 1. 2024-01-12. PMID:38216560. |
furthermore, the knockout of nlrp3 in microglia alleviated the trained immunity and reduced the harmful effects of microinfarcts on recurrent stroke. |
2024-01-12 |
2024-01-15 |
Not clear |
| Huijie Duan, Junya Hu, Yang Deng, Junqing Zou, Wangli Ding, Qiang Peng, Rui Duan, Jianguo Sun, Junrong Zh. Berberine Mediates the Production of Butyrate to Ameliorate Cerebral Ischemia via the Gut Microbiota in Mice. Nutrients. vol 16. issue 1. 2024-01-11. PMID:38201839. |
in addition, butyric acid could inhibit the activation of the microglia and astrocytes in the brains of model mice, thereby inhibiting the generation of pro-inflammatory factors il-6, il-1β and tnf-α as well as improving stroke outcomes. |
2024-01-11 |
2024-01-13 |
mouse |
| Xiao-Li Min, Wen-Ji Jia, Li Guo, Rui Jing, Xiao-Hong Zhao, Jia-Yi Hu, Xu-Hui Li, Wei Liu, Tao Wang, Xing-Kui Do. Brain microvascular endothelial cell-derived exosomes transmitting circ_0000495 promote microglial M1-polarization and endothelial cell injury under hypoxia condition. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 2. 2024-01-09. PMID:38193649. |
however, the role of hbmvecs-derived exosomes in microglia polarization after stroke remains unknown. |
2024-01-09 |
2024-01-10 |
mouse |
| Anna M Plana. Role of microglia in stroke. Glia. 2024-01-04. PMID:38173414. |
role of microglia in stroke. |
2024-01-04 |
2024-01-06 |
human |
| Anna M Plana. Role of microglia in stroke. Glia. 2024-01-04. PMID:38173414. |
accurate profiling of microglia phenotypes, alongside with a more precise understanding of the associated post-ischemic tissue conditions, is a necessary step to serve as the potential foundation for focused interventions in human stroke. |
2024-01-04 |
2024-01-06 |
human |
| Huiya Li, Pinyi Liu, Bing Zhang, Zengqiang Yuan, Mengdi Guo, Xinxin Zou, Yi Qian, Shiji Deng, Liwen Zhu, Xiang Cao, Tao Tao, Shengnan Xia, Xinyu Bao, Yun X. Acute ischemia induces spatially and transcriptionally distinct microglial subclusters. Genome medicine. vol 15. issue 1. 2023-12-12. PMID:38082331. |
microglia immediately respond to ischemic insult and initiate immune inflammation, playing an important role in the cellular injury after stroke. |
2023-12-12 |
2023-12-17 |
Not clear |
| Xin Gao, Gang Su, Miao Chai, Minghui Shen, Zhenzhen Hu, Wei Chen, Juan Gao, Ruixin Li, Tianfei Ma, Yang An, Zhenchang Zhan. Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia. Neurochemistry international. 2023-12-11. PMID:38081419. |
activated microglia participate in the pathological processes after stroke through polarization, autophagy, phagocytosis, pyroptosis, ferroptosis, apoptosis, and necrosis, thereby influencing the injury and repair following stroke. |
2023-12-11 |
2023-12-17 |
Not clear |
| Xin Gao, Gang Su, Miao Chai, Minghui Shen, Zhenzhen Hu, Wei Chen, Juan Gao, Ruixin Li, Tianfei Ma, Yang An, Zhenchang Zhan. Research progress on mechanisms of ischemic stroke: Regulatory pathways involving Microglia. Neurochemistry international. 2023-12-11. PMID:38081419. |
autophagy and phagocytosis in microglia following ischemia are dynamic processes, where moderate levels promote cell survival, while excessive responses may exacerbate neurofunctional deficits following stroke. |
2023-12-11 |
2023-12-17 |
Not clear |
| Jingwei Song, Syed Aqib Ali Zaidi, Liangge He, Shuai Zhang, Guangqian Zho. Integrative Analysis of Machine Learning and Molecule Docking Simulations for Ischemic Stroke Diagnosis and Therapy. Molecules (Basel, Switzerland). vol 28. issue 23. 2023-12-09. PMID:38067435. |
the rna velocity and pseudo time analysis showed that microglia subcluster 0 would develop toward subcluster 2 within 24 h from stroke onset. |
2023-12-09 |
2023-12-17 |
Not clear |
| Jingwei Song, Syed Aqib Ali Zaidi, Liangge He, Shuai Zhang, Guangqian Zho. Integrative Analysis of Machine Learning and Molecule Docking Simulations for Ischemic Stroke Diagnosis and Therapy. Molecules (Basel, Switzerland). vol 28. issue 23. 2023-12-09. PMID:38067435. |
az_628, which screened from cmap analysis, was found to have lower binding energy with mmp12, lgals3, fam20c, capg, pkm2, sdc4, and itga5 in microglia subcluster 2 and maybe a therapeutic agent for the poor development of microglia subcluster 2 after stroke. |
2023-12-09 |
2023-12-17 |
Not clear |
| Lu Yu, Zuohui Zhang, Hao Chen, Miao Wang, Wenqi Mao, Jinxia Hu, Dandan Zuo, Bingchen Lv, Weifeng Wu, Suhua Qi, Guiyun Cu. Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke. Bioengineering & translational medicine. vol 8. issue 6. 2023-12-01. PMID:38023701. |
remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating hgf after acute ischemia stroke. |
2023-12-01 |
2023-12-07 |
mouse |
| Lu Yu, Zuohui Zhang, Hao Chen, Miao Wang, Wenqi Mao, Jinxia Hu, Dandan Zuo, Bingchen Lv, Weifeng Wu, Suhua Qi, Guiyun Cu. Remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating HGF after acute ischemia stroke. Bioengineering & translational medicine. vol 8. issue 6. 2023-12-01. PMID:38023701. |
remote limb ischemic postconditioning inhibits microglia pyroptosis by modulating hgf after acute ischemia stroke. |
2023-11-29 |
2023-12-07 |
mouse |
| Weizhuo Lu, Zhiwu Chen, Jiyue We. Flavonoids and ischemic stroke-induced neuroinflammation: Focus on the glial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-11-28. PMID:38016362. |
after stroke onset, microglia, astrocytes and the infiltrating immune cells contribute to a complicated neuroinflammation cascade and play the complicated roles in the pathophysiological variations of ischemic stroke. |
2023-11-28 |
2023-12-07 |
Not clear |
| Nikolett Lénárt, Csaba Cserép, Eszter Császár, Balázs Pósfai, Ádám Déne. Microglia-neuron-vascular interactions in ischemia. Glia. 2023-11-15. PMID:37964690. |
while the contribution of non-neuronal cells to stroke pathophysiology is increasingly recognized, recent data show that microglia, the main immune cells of the central nervous system parenchyma, play previously unrecognized roles in basic physiological processes beyond their inflammatory functions, which markedly change during ischemic conditions. |
2023-11-15 |
2023-11-20 |
Not clear |
| Miguel M Lino, Tiago Rondão, Arnab Banerjee, Inês Aires, Magda Rodrigues, Tiago Reis, António Santinha, Dominique Fernandes, Débora Serrenho, Tomás Sobrino, João Sargento-Freitas, Frederico C Pereira, Ana Luísa Carvalho, Lino Ferreir. Small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. Nanoscale. 2023-11-07. PMID:37933179. |
small extracellular vesicles administered directly in the brain promote neuroprotection and decreased microglia reactivity in a stroke mouse model. |
2023-11-07 |
2023-11-08 |
mouse |
| Kimberly Prescott, Alexandra E Münch, Evan Brahms, Maya M Weigel, Kenya Inoue, Marion S Buckwalter, Shane A Liddelow, Todd C Peterso. Blocking Formation of Neurotoxic Reactive Astrocytes is Beneficial Following Stroke. bioRxiv : the preprint server for biology. 2023-10-31. PMID:37905154. |
microglia and astrocytes play an important role in the neuroinflammatory response and contribute to both the destruction of neighboring tissue as well as the resolution of inflammation following stroke. |
2023-10-31 |
2023-11-08 |
Not clear |
| Fatemehsadat Seyedaghamiri, Mohammad Hossein Geranmayeh, Tahereh Ghadiri, Abbas Ebrahimi-Kalan, Leila Hossein. A new insight into the role of pericytes in ischemic stroke. Acta neurologica Belgica. 2023-10-07. PMID:37805645. |
microglia regulate immunity and inflammatory response after stroke. |
2023-10-07 |
2023-10-15 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
changes in microglia during drug treatment of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |
| Ling-Jing Zhang, Hong-Su Zhou, Shi-Ya Wang, Yi-Huan Guan, Chao Zhang, De-Rong Fan. Changes in microglia during drug treatment of stroke. Ibrain. vol 8. issue 2. 2023-10-03. PMID:37786889. |
microglia play a complex role in the process of stroke. |
2023-10-03 |
2023-10-07 |
Not clear |