| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yehao Zhang, Lan Miao, Qing Peng, Xiaodi Fan, Wenting Song, Bin Yang, Peng Zhang, Guangyu Liu, Jianxun Li. Parthenolide modulates cerebral ischemia-induced microglial polarization and alleviates neuroinflammatory injury via the RhoA/ROCK pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 105. 2022-08-10. PMID:35947899. |
microglia can be activated as proinflammatory (m1) phenotypes and anti-inflammatory (m2) phenotypes after stroke. |
2022-08-10 |
2023-08-14 |
Not clear |
| Stefano Raffaele, Marta Fumagall. Dynamics of Microglia Activation in the Ischemic Brain: Implications for Myelin Repair and Functional Recovery. Frontiers in cellular neuroscience. vol 16. 2022-07-28. PMID:35899017. |
some molecular signals regulating the pro-regenerative functions of microglia after stroke have been highlighted to provide new possible therapeutic targets involved in the protective functions of these cells. |
2022-07-28 |
2023-08-14 |
Not clear |
| Xiao Ke, Manfei Deng, Zhuoze Wu, Hongyan Yu, Dian Yu, Hao Li, Youming Lu, Kai Shu, Lei Pe. miR-34b-3p Inhibition of eIF4E Causes Post-stroke Depression in Adult Mice. Neuroscience bulletin. 2022-07-08. PMID:35802246. |
together, our data demonstrated that insufficient mir34b-3p after stroke cannot inhibit eif4e translation, which causes psd by the activation of microglia in the hippocampus. |
2022-07-08 |
2023-08-14 |
mouse |
| Hyo Jung Shin, Ka Young Lee, Joon Won Kang, Seung Gyu Choi, Dong Woon Kim, Yoon Young Y. Perampanel Reduces Brain Damage via Induction of M2 Microglia in a Neonatal Rat Stroke Model. International journal of nanomedicine. vol 17. 2022-07-05. PMID:35782016. |
perampanel reduces brain damage via induction of m2 microglia in a neonatal rat stroke model. |
2022-07-05 |
2023-08-14 |
rat |
| Hyo Jung Shin, Ka Young Lee, Joon Won Kang, Seung Gyu Choi, Dong Woon Kim, Yoon Young Y. Perampanel Reduces Brain Damage via Induction of M2 Microglia in a Neonatal Rat Stroke Model. International journal of nanomedicine. vol 17. 2022-07-05. PMID:35782016. |
in this study, we investigated the effect of perampanel (per)-loaded poly lactic-co-glycolic acid (plga) by targeting microglia in perinatal stroke. |
2022-07-05 |
2023-08-14 |
rat |
| Shin-Shin Lee, Li Pang, Yin Cheng, Jia Xin Liu, Anson Cho Kiu Ng, Gilberto Ka Kit Leun. A previous hemorrhagic stroke protects against a subsequent stroke via microglia alternative polarization. Communications biology. vol 5. issue 1. 2022-07-02. PMID:35780249. |
a previous hemorrhagic stroke protects against a subsequent stroke via microglia alternative polarization. |
2022-07-02 |
2023-08-14 |
mouse |
| Yoshiki Hase, Kamar E Ameen-Ali, Rachel Waller, Julie E Simpson, Charlotte Stafford, Ayushi Mahesh, Lucy Ryan, Lucy Pickering, Caroline Bodman, Mai Hase, Delphine Boche, Karen Horsburgh, Stephen B Wharton, Raj N Kalari. Differential perivascular microglial activation in the deep white matter in vascular dementia developed post-stroke. Brain pathology (Zurich, Switzerland). 2022-06-24. PMID:35748290. |
with the hypothesis that perivascular microglia are involved as neuroinflammatory components of the gliovascular unit contributing to white matter hyperintensities on mri and pathophysiology, we assessed their status in stroke survivors who develop dementia. |
2022-06-24 |
2023-08-14 |
human |
| Clara Bourget, Kelsey V Adams, Cindi M Morshea. Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke. Journal of neuroinflammation. vol 19. issue 1. 2022-06-15. PMID:35705953. |
reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke. |
2022-06-15 |
2023-08-14 |
mouse |
| Clara Bourget, Kelsey V Adams, Cindi M Morshea. Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke. Journal of neuroinflammation. vol 19. issue 1. 2022-06-15. PMID:35705953. |
given metformin's demonstrated anti-inflammatory properties, we investigated its role in regulating the microglia activation and used a microglia ablation strategy to investigate the microglia-mediated outcomes in a mouse model of neonatal stroke. |
2022-06-15 |
2023-08-14 |
mouse |
| Sinai Kim, Wonhyo Lee, Huiju Jo, Seong-Keun Sonn, Se-Jin Jeong, Seungwoon Seo, Joowon Suh, Jing Jin, Hyae Yon Kweon, Tae Kyeong Kim, Shin Hye Moon, Sejin Jeon, Jong Woo Kim, Yu Ri Kim, Eun-Woo Lee, Hwa Kyoung Shin, Sung Ho Park, Goo Taeg O. The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke. Redox biology. vol 54. 2022-06-10. PMID:35688114. |
here, we identified a new type of microglia associated with stroke in the i/r injured brain. |
2022-06-10 |
2023-08-14 |
Not clear |
| Zhizhun Mo, Zhongyi Zeng, Yuxiang Liu, Linsheng Zeng, Jiansong Fang, Yinzhong M. Activation of Wnt/Beta-Catenin Signaling Pathway as a Promising Therapeutic Candidate for Cerebral Ischemia/Reperfusion Injury. Frontiers in pharmacology. vol 13. 2022-06-07. PMID:35668927. |
to better understand the therapeutic potential of wnt as a novel target for stroke, we reviewed the role of wnt signaling in the pathogenesis of stroke in different cell types, including endothelial cells, neurons, oligodendrocytes, and microglia. |
2022-06-07 |
2023-08-14 |
Not clear |
| Jong Youl Kim, Jiwon Kim, Meiying Huang, Renée Kosonen, Jong Eun Le. CCR4 and CCR5 Involvement in Monocyte-Derived Macrophage Migration in Neuroinflammation. Frontiers in immunology. vol 13. 2022-05-31. PMID:35634277. |
microglia, resident macrophages in the brain, play major roles in neuroinflammation after an acute many neurological diseases, including stroke. |
2022-05-31 |
2023-08-13 |
Not clear |
| Jong Youl Kim, Jiwon Kim, Meiying Huang, Renée Kosonen, Jong Eun Le. CCR4 and CCR5 Involvement in Monocyte-Derived Macrophage Migration in Neuroinflammation. Frontiers in immunology. vol 13. 2022-05-31. PMID:35634277. |
our recent animal stroke model showed that interleukin (il)-4 and il-13 released by microglia are converted into monocyte-derived macrophages. |
2022-05-31 |
2023-08-13 |
Not clear |
| Ping Li, Xue Luo, Zhen Luo, Gen-Lin He, Ting-Ting Shen, Xue-Ting Yu, Ze-Ze Wang, Yu-Long Tan, Xiao-Qian Liu, Xue-Sen Yan. Increased miR-155 in Microglial Exosomes Following Heat Stress Accelerates Neuronal Autophagy Frontiers in cellular neuroscience. vol 16. 2022-05-31. PMID:35634460. |
in our previous studies, both activated microglia and increased neuronal autophagy were found in the cortices of mice with heat stroke. |
2022-05-31 |
2023-08-13 |
mouse |
| Zhaoxia Wang, Xinming Li, Zhixing Shao, ZhengFang, Yueping Zha. Retracted Article: Elevation of USP4 antagonizes oxygen glucose deprivation/reoxygenation-evoked microglia activation and neuroinflammation-mediated neurotoxicity RSC advances. vol 9. issue 41. 2022-05-09. PMID:35530618. |
microglia activation after a stroke results in the release of pro-inflammatory cytokines that can further aggravate brain damage. |
2022-05-09 |
2023-08-13 |
Not clear |
| Wen-Yu Ma, Sha-Sha Wang, Qing-Lin Wu, Xin Zhou, Shi-Feng Chu, Nai-Hong Che. The versatile role of TREM2 in regulating of microglia fate in the ischemic stroke. International immunopharmacology. vol 109. 2022-05-07. PMID:35525233. |
microglia are the earliest activated and the longest lasting immune cells after stroke, and they participate in almost all the pathological reactions after stroke. |
2022-05-07 |
2023-08-13 |
Not clear |
| Wen-Yu Ma, Sha-Sha Wang, Qing-Lin Wu, Xin Zhou, Shi-Feng Chu, Nai-Hong Che. The versatile role of TREM2 in regulating of microglia fate in the ischemic stroke. International immunopharmacology. vol 109. 2022-05-07. PMID:35525233. |
however, trem2 does not provide a systematic summary of the functional transformation and intrinsic molecular mechanisms of microglia after stroke. |
2022-05-07 |
2023-08-13 |
Not clear |
| Wen-Yu Ma, Sha-Sha Wang, Qing-Lin Wu, Xin Zhou, Shi-Feng Chu, Nai-Hong Che. The versatile role of TREM2 in regulating of microglia fate in the ischemic stroke. International immunopharmacology. vol 109. 2022-05-07. PMID:35525233. |
in this paper, we have summarized the functional changes of trem2 in microglia after stroke in recent years, and found that trem2 has important effects on energy metabolism, phagocytosis and anti-inflammatory function of microglia after stroke, suggesting that trem2 is a potential therapeutic target for the treatment of stroke. |
2022-05-07 |
2023-08-13 |
Not clear |
| Hai Xiao, Shuqin Han, Huricha Baigud. Regulation of microglia polarization RSC advances. vol 11. issue 52. 2022-05-02. PMID:35493551. |
regulation of microglia polarization the pro-inflammatory polarization of microglia after stroke is one of the major causes of secondary brain injury. |
2022-05-02 |
2023-08-13 |
Not clear |
| Irene F Ugidos, Cristiana Pistono, Paula Korhonen, Mireia Gómez-Budia, Valeriia Sitnikova, Pamela Klecki, Iveta Stanová, Jukka Jolkkonen, Tarja Mal. Sex Differences in Poststroke Inflammation: a Focus on Microglia Across the Lifespan. Stroke. vol 53. issue 5. 2022-04-25. PMID:35468000. |
poststroke neuroinflammation is geared largely by brain microglia and infiltrating peripheral immune cells and largely contributes to sex differences in the outcome of stroke. |
2022-04-25 |
2023-08-13 |
Not clear |