| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Yu Ma, Sha-Sha Wang, Qing-Lin Wu, Xin Zhou, Shi-Feng Chu, Nai-Hong Che. The versatile role of TREM2 in regulating of microglia fate in the ischemic stroke. International immunopharmacology. vol 109. 2022-05-07. PMID:35525233. |
in this paper, we have summarized the functional changes of trem2 in microglia after stroke in recent years, and found that trem2 has important effects on energy metabolism, phagocytosis and anti-inflammatory function of microglia after stroke, suggesting that trem2 is a potential therapeutic target for the treatment of stroke. |
2022-05-07 |
2023-08-13 |
Not clear |
| Hai Xiao, Shuqin Han, Huricha Baigud. Regulation of microglia polarization RSC advances. vol 11. issue 52. 2022-05-02. PMID:35493551. |
regulation of microglia polarization the pro-inflammatory polarization of microglia after stroke is one of the major causes of secondary brain injury. |
2022-05-02 |
2023-08-13 |
Not clear |
| Irene F Ugidos, Cristiana Pistono, Paula Korhonen, Mireia Gómez-Budia, Valeriia Sitnikova, Pamela Klecki, Iveta Stanová, Jukka Jolkkonen, Tarja Mal. Sex Differences in Poststroke Inflammation: a Focus on Microglia Across the Lifespan. Stroke. vol 53. issue 5. 2022-04-25. PMID:35468000. |
poststroke neuroinflammation is geared largely by brain microglia and infiltrating peripheral immune cells and largely contributes to sex differences in the outcome of stroke. |
2022-04-25 |
2023-08-13 |
Not clear |
| Hubert Doleżyczek, Piotr Kasprzycki, Jakub Włodarczyk, Maciej Wojtkowski, Monika Malinowsk. Optical coherence tomography reveals heterogeneity of the brain tissue and vasculature in the ischemic region after photothrombotic stroke in mice. Acta neurobiologiae experimentalis. vol 82. issue 1. 2022-04-22. PMID:35451428. |
the goal of our research was analysis of vascularity of the ischemic area during 2‑week progress of stroke and correlating the hypo‑ and hyperreflective oct scattering areas with the location of activated microglia and astroglia. |
2022-04-22 |
2023-08-13 |
mouse |
| Confidence Dordoe, Xue Wang, Ping Lin, Zhengyi Wang, Jian Hu, Dongxue Wang, Yani Fang, Fei Liang, Shasha Ye, Jun Chen, Yeli Zhao, Ye Xiong, Yunjun Yang, Li Lin, Xianfeng L. Non-mitogenic fibroblast growth factor 1 protects against ischemic stroke by regulating microglia/macrophage polarization through Nrf2 and NF-κB pathways. Neuropharmacology. 2022-04-22. PMID:35452626. |
the present study aimed to investigate the effects and mechanism of the neuroprotective ability of nmfgf1 on microglia in mice after photothrombosis (pt) stroke model, to determine whether it could ameliorate ischemic injury in stroke experiment. |
2022-04-22 |
2023-08-13 |
mouse |
| Lulu Jin, Zhixin Zhu, Liangjie Hong, Zhefeng Qian, Fang Wang, Zhengwei Ma. ROS-responsive 18β-glycyrrhetic acid-conjugated polymeric nanoparticles mediate neuroprotection in ischemic stroke through HMGB1 inhibition and microglia polarization regulation. Bioactive materials. vol 19. 2022-04-13. PMID:35415314. |
dga presented excellent therapeutic efficacy in stroke mice, as evidenced by the reduction of infarct volume, recovery of motor function, suppressed of m1 microglia activation and enhanced m2 activation, and induction of neurogenesis. |
2022-04-13 |
2023-08-13 |
mouse |
| Teng Wan, Yunling Huang, Xiaoyu Gao, Wanpeng Wu, Weiming Gu. Microglia Polarization: A Novel Target of Exosome for Stroke Treatment. Frontiers in cell and developmental biology. vol 10. 2022-03-31. PMID:35356292. |
microglia polarization: a novel target of exosome for stroke treatment. |
2022-03-31 |
2023-08-13 |
human |
| Teng Wan, Yunling Huang, Xiaoyu Gao, Wanpeng Wu, Weiming Gu. Microglia Polarization: A Novel Target of Exosome for Stroke Treatment. Frontiers in cell and developmental biology. vol 10. 2022-03-31. PMID:35356292. |
microglia are core members of central intrinsic immune regulatory cells, which play an important regulatory role in the pathogenesis and progression of stroke. |
2022-03-31 |
2023-08-13 |
human |
| Teng Wan, Yunling Huang, Xiaoyu Gao, Wanpeng Wu, Weiming Gu. Microglia Polarization: A Novel Target of Exosome for Stroke Treatment. Frontiers in cell and developmental biology. vol 10. 2022-03-31. PMID:35356292. |
this research reviews the role of exosomes in the regulation of microglia polarization and reveals their potential value in stroke treatment. |
2022-03-31 |
2023-08-13 |
human |
| Hongrui Zhu, Yi Guo, Ailing Huang, Huidan Shen, Yang Chen, Jingyi Song, Ao Guan, Liang Wu, Huiting Wang, Bin Den. HDAC3-Regulated PGE2 Production by Microglia Induces Phobic Anxiety Susceptibility After Stroke and Pointedly Exploiting a Signal-Targeted Gamma Visual Stimulation New Therapy. Frontiers in immunology. vol 13. 2022-03-07. PMID:35251047. |
hdac3-regulated pge2 production by microglia induces phobic anxiety susceptibility after stroke and pointedly exploiting a signal-targeted gamma visual stimulation new therapy. |
2022-03-07 |
2023-08-13 |
Not clear |
| Yi-Sha Guo, Mei Yuan, Yu Han, Xin-Ya Shen, Zhen-Kun Gao, Xia B. Effects of enriched environment on microglia and functional white matter recovery in rats with post stroke cognitive impairment. Neurochemistry international. 2022-02-05. PMID:35121010. |
effects of enriched environment on microglia and functional white matter recovery in rats with post stroke cognitive impairment. |
2022-02-05 |
2023-08-13 |
rat |
| Cristina Barca, Amanda J Kiliaan, Lydia Wachsmuth, Claudia Foray, Sven Hermann, Cornelius Faber, Michael Schaefers, Maximilian Wiesmann, Bastian Zinnhardt, Andreas H Jacob. Short-term colony stimulating factor-1 receptor inhibition-induced repopulation after stroke assessed by longitudinal Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2022-02-04. PMID:35115368. |
short-term colony stimulating factor-1 receptor inhibition-induced repopulation after stroke assessed by longitudinal studies on colony stimulating factor-1 receptor (csf-1r) inhibition-induced microglia depletion indicated that inhibitor withdrawal allowed the renewal of the microglial compartment via repopulation and resolved the inflammatory imbalance. |
2022-02-04 |
2023-08-13 |
mouse |
| Junqiu Jia, Lixuan Yang, Yan Chen, Lili Zheng, Yanting Chen, Yun Xu, Meijuan Zhan. The Role of Microglial Phagocytosis in Ischemic Stroke. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082781. |
during the past decades, microglial polarization and chemotactic properties have been well-studied, whereas less attention has been paid to phagocytic phenotypes of microglia in stroke. |
2022-01-27 |
2023-08-13 |
Not clear |
| Junqiu Jia, Lixuan Yang, Yan Chen, Lili Zheng, Yanting Chen, Yun Xu, Meijuan Zhan. The Role of Microglial Phagocytosis in Ischemic Stroke. Frontiers in immunology. vol 12. 2022-01-27. PMID:35082781. |
generally, whether phagocytosis mediated by microglia plays a beneficial or detrimental role in stroke remains controversial, which calls for further investigations. |
2022-01-27 |
2023-08-13 |
Not clear |
| Yao Lin, Tingting Huang, Weimin Shen, Qiongyi Pang, Qingfeng Xie, Xiang Chen, Fengxia T. TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury. Journal of molecular neuroscience : MN. 2022-01-18. PMID:35041191. |
in recent years, it has been reported that autophagy in microglia played an important role in inflammatory response after stroke. |
2022-01-18 |
2023-08-13 |
Not clear |
| Mandeep Kaur, Saurabh Sharm. Molecular mechanisms of cognitive impairment associated with stroke. Metabolic brain disease. 2022-01-14. PMID:35029798. |
the pathophysiology of stroke associated cognitive impairment is complex and recent molecular, cellular, and animal models studies have revealed that multiple cellular changes have been implicated, including altered redox state, mitochondrial dysfunction, disruption of the blood-brain barrier, perivascular spacing, glymphatic system impairment, microglia activation and amyloid-β deposition in the parenchyma of the brain. |
2022-01-14 |
2023-08-13 |
Not clear |
| Xiao-Wen Lian, Bin Lu. Knockdown of NEAT1 induced microglial M2 polarization via miR‑374a‑5p/NFAT5 axis to inhibit inflammatory response caused by OGD/R. Acta neurobiologiae experimentalis. vol 81. issue 4. 2022-01-11. PMID:35014985. |
knockdown of neat1 regulated ogd/r injury of chme5 cells via mir‑374a‑5p/nfat5 axis to induce the shifting of microglia from m1 to m2 and inhibit inflammatory response, making it a potential target for stroke treatment. |
2022-01-11 |
2023-08-13 |
Not clear |
| Ming-Xing Cheng, Chen-Hui Li, Wei Meng, Chen Wan. [Dual roles and mechanism of microglia in ischemic stroke]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 6. 2021-12-28. PMID:34961871. |
here, we briefly describe the mechanism of microglia activation after stroke, and comprehensively review the dual role of microglia in neurodegeneration and regeneration after stroke. |
2021-12-28 |
2023-08-13 |
Not clear |
| Ming-Xing Cheng, Chen-Hui Li, Wei Meng, Chen Wan. [Dual roles and mechanism of microglia in ischemic stroke]. Sheng li xue bao : [Acta physiologica Sinica]. vol 73. issue 6. 2021-12-28. PMID:34961871. |
in-depth exploration of the cytotoxic and protective mechanisms of microglia will provide new targets and new strategies for stroke treatment. |
2021-12-28 |
2023-08-13 |
Not clear |
| Susanna R Var, Anala V Shetty, Andrew W Grande, Walter C Low, Maxim C Cheera. Microglia and Macrophages in Neuroprotection, Neurogenesis, and Emerging Therapies for Stroke. Cells. vol 10. issue 12. 2021-12-24. PMID:34944064. |
microglia and macrophages in neuroprotection, neurogenesis, and emerging therapies for stroke. |
2021-12-24 |
2023-08-13 |
Not clear |