| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bailey A Dyck, Mattea L Tan, Ritesh P Daya, Dipannita Basu, Christal D R Sookram, Nancy Thomas, Ram K Mishr. Behavioral effects of non-viral mediated RNA interference of synapsin II in the medial prefrontal cortex of the rat. Schizophrenia research. vol 137. issue 1-3. 2012-09-18. PMID:22341900. |
researchers have demonstrated reductions in synapsin ii mrna and protein in post-mortem prefrontal cortex and hippocampus samples from patients with schizophrenia. |
2012-09-18 |
2023-08-12 |
mouse |
| Hidenaga Yamamori, Ryota Hashimoto, Kazutaka Ohi, Yuka Yasuda, Motoyuki Fukumoto, Emiko Kasahara, Atsuo Sekiyama, Satomi Umeda-Yano, Takeya Okada, Masao Iwase, Hiroaki Kazui, Akira Ito, Masatoshi Taked. A promoter variant in the chitinase 3-like 1 gene is associated with serum YKL-40 level and personality trait. Neuroscience letters. vol 513. issue 2. 2012-09-18. PMID:22366530. |
the chitinase 3-like 1 (chi3l1) gene, a cellular survival factor against several environmental and psychosocial stresses, has been sown to be more highly expressed in the hippocampus and prefrontal cortex of patients with schizophrenia than unaffected individuals. |
2012-09-18 |
2023-08-12 |
Not clear |
| Mireille Nieuwenhuis, Neeltje E M van Haren, Hilleke E Hulshoff Pol, Wiepke Cahn, René S Kahn, Hugo G Schnac. Classification of schizophrenia patients and healthy controls from structural MRI scans in two large independent samples. NeuroImage. vol 61. issue 3. 2012-09-17. PMID:22507227. |
the model's discriminative pattern showed, amongst other differences, gray matter density decreases in frontal and superior temporal lobes and hippocampus in schizophrenia patients with respect to healthy controls and increases in gray matter density in basal ganglia and left occipital lobe and. |
2012-09-17 |
2023-08-12 |
human |
| Hai-Ying Shen, Philipp Singer, Nikki Lytle, Catherine J Wei, Jing-Quan Lan, Rebecca L Williams-Karnesky, Jiang-Fan Chen, Benjamin K Yee, Detlev Boiso. Adenosine augmentation ameliorates psychotic and cognitive endophenotypes of schizophrenia. The Journal of clinical investigation. vol 122. issue 7. 2012-09-11. PMID:22706302. |
this functional double dissociation between striatal and hippocampal adenosine demonstrated in adk transgenic mice highlights the independent contributions of these two interconnected brain regions in the pathophysiology of schizophrenia and thus provides the rationale for developing local adenosine augmentation therapies for the treatment of schizophrenia. |
2012-09-11 |
2023-08-12 |
mouse |
| Carol A Tamminga, Deborah R Medof. Studies in schizophrenia: pathophysiology and treatment. Dialogues in clinical neuroscience. vol 4. issue 4. 2012-09-10. PMID:22033751. |
studies on the pathophysiology of schizophrenia have implicated the limbic cortex, using postmortem, structural, and functional data, especially in the hippocampus (hc) and the anterior cingulate cortex (acc). |
2012-09-10 |
2023-08-12 |
Not clear |
| Barbara K Lipsk. Neonatal disconnection of the rat hippocampus: a neurodevelopmental model of schizophrenia. Dialogues in clinical neuroscience. vol 4. issue 4. 2012-09-10. PMID:22034469. |
neonatal disconnection of the rat hippocampus: a neurodevelopmental model of schizophrenia. |
2012-09-10 |
2023-08-12 |
rat |
| Jerome J Maller, Zafiris J Daskalakis, Richard H S Thomson, Melissa Daigle, Mera S Barr, Paul B Fitzgeral. Hippocampal volumetrics in treatment-resistant depression and schizophrenia: the devil's in de-tail. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:20882552. |
hippocampal volumetrics in treatment-resistant depression and schizophrenia: the devil's in de-tail. |
2012-09-06 |
2023-08-12 |
human |
| Jerome J Maller, Zafiris J Daskalakis, Richard H S Thomson, Melissa Daigle, Mera S Barr, Paul B Fitzgeral. Hippocampal volumetrics in treatment-resistant depression and schizophrenia: the devil's in de-tail. Hippocampus. vol 22. issue 1. 2012-09-06. PMID:20882552. |
studies of patients with major depressive disorder (mdd) and schizophrenia (sch) have revealed reduced hippocampal volumes, but findings have been inconsistent due to sample and measurement differences. |
2012-09-06 |
2023-08-12 |
human |
| Kara Kittelberger, Elizabeth E Hur, Saba Sazegar, Vidya Keshavan, Bernat Kocsi. Comparison of the effects of acute and chronic administration of ketamine on hippocampal oscillations: relevance for the NMDA receptor hypofunction model of schizophrenia. Brain structure & function. vol 217. issue 2. 2012-09-04. PMID:21979451. |
comparison of the effects of acute and chronic administration of ketamine on hippocampal oscillations: relevance for the nmda receptor hypofunction model of schizophrenia. |
2012-09-04 |
2023-08-12 |
human |
| Zong-Ling He, Wei Deng, Ming-Li Li, Zhuang-Fei Chen, David A Collier, Xiaohong Ma, Tao L. Detection of metabolites in the white matter of frontal lobes and hippocampus with proton in first-episode treatment-naïve schizophrenia patients. Early intervention in psychiatry. vol 6. issue 2. 2012-08-28. PMID:21951785. |
detection of metabolites in the white matter of frontal lobes and hippocampus with proton in first-episode treatment-naïve schizophrenia patients. |
2012-08-28 |
2023-08-12 |
Not clear |
| Zong-Ling He, Wei Deng, Ming-Li Li, Zhuang-Fei Chen, David A Collier, Xiaohong Ma, Tao L. Detection of metabolites in the white matter of frontal lobes and hippocampus with proton in first-episode treatment-naïve schizophrenia patients. Early intervention in psychiatry. vol 6. issue 2. 2012-08-28. PMID:21951785. |
this study aimed to investigate the changes of the metabolites in the white matter of frontal lobes and hippocampus in schizophrenia by using proton magnetic resonance spectroscopy ((1) h-mrs). |
2012-08-28 |
2023-08-12 |
Not clear |
| Jyotirmoy Banerjee, Manickavasagom Alkondon, Edna F R Pereira, Edson X Albuquerqu. Regulation of GABAergic inputs to CA1 pyramidal neurons by nicotinic receptors and kynurenic acid. The Journal of pharmacology and experimental therapeutics. vol 341. issue 2. 2012-08-20. PMID:22344459. |
impaired α7 nicotinic acetylcholine receptor (nachr) function and gabaergic transmission in the hippocampus and elevated brain levels of kynurenic acid (kyna), an astrocyte-derived metabolite of the kynurenine pathway, are key features of schizophrenia. |
2012-08-20 |
2023-08-12 |
Not clear |
| Carlos Eduardo Macedo, Marie-Josée Angst, Serge Gobaille, Carmen Schleef, Blandine Guignard, Thierry Guiberteau, Alain Louilot, Guy Sandne. Prefrontal dopamine release and sensory-specific satiety altered in rats with neonatal ventral hippocampal lesions. Behavioural brain research. vol 231. issue 1. 2012-08-20. PMID:22409974. |
rats with a neonatal ventral hippocampal lesion (nvhl) have been used to model certain features of schizophrenia because they display dopaminergic activity and behavioral alterations consistent with a dysfunctional prefrontal cortex after puberty. |
2012-08-20 |
2023-08-12 |
rat |
| Louisa Lyon, Philip W J Burnet, James N C Kew, Corrado Corti, J Nicholas P Rawlins, Tracy Lane, Bianca De Filippis, Paul J Harrison, David M Bannerma. Fractionation of spatial memory in GRM2/3 (mGlu2/mGlu3) double knockout mice reveals a role for group II metabotropic glutamate receptors at the interface between arousal and cognition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 13. 2012-08-14. PMID:21832989. |
group ii metabotropic glutamate receptors (mglur2 and mglur3, encoded by grm2 and grm3) are implicated in hippocampal function and cognition, and in the pathophysiology and treatment of schizophrenia and other psychiatric disorders. |
2012-08-14 |
2023-08-12 |
mouse |
| Kristian Liaury, Tsuyoshi Miyaoka, Toshiko Tsumori, Motohide Furuya, Rei Wake, Masa Ieda, Keiko Tsuchie, Michiyo Taki, Kotomi Ishihara, Andi Jayalangkara Tanra, Jun Horiguch. Morphological features of microglial cells in the hippocampal dentate gyrus of Gunn rat: a possible schizophrenia animal model. Journal of neuroinflammation. vol 9. 2012-08-14. PMID:22424389. |
morphological features of microglial cells in the hippocampal dentate gyrus of gunn rat: a possible schizophrenia animal model. |
2012-08-14 |
2023-08-12 |
rat |
| Inna Gaisler-Salomon, Yvonne Wang, Nao Chuhma, Hong Zhang, Yaela N Golumbic, Andra Mihali, Ottavio Arancio, Etienne Sibille, Stephen Raypor. Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation. Hippocampus. vol 22. issue 5. 2012-08-14. PMID:22431402. |
glutaminase-deficient mice (gls1 hets), with reduced glutamate recycling, have a focal reduction in hippocampal activity, mainly in ca1, and manifest behavioral and neurochemical phenotypes suggestive of schizophrenia resilience. |
2012-08-14 |
2023-08-12 |
mouse |
| Sara Sannino, Fabio Russo, Giulia Torromino, Valentina Pendolino, Paolo Calabresi, Elvira De Leonibu. Role of the dorsal hippocampus in object memory load. Learning & memory (Cold Spring Harbor, N.Y.). vol 19. issue 5. 2012-08-14. PMID:22523415. |
these results have important heuristic and clinical implications because they open new perspective toward the understanding of the role of the hippocampus in item memory and in memory span deficits occurring in human pathologies, such as alzheimer's disease and schizophrenia. |
2012-08-14 |
2023-08-12 |
mouse |
| Umberto Volpe, Armida Mucci, Mario Quarantelli, Silvana Galderisi, Mario Ma. Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 37. issue 2. 2012-08-10. PMID:22349577. |
the aim of the present study was to investigate whether patients with ds differed from those with nondeficit schizophrenia (nds) with respect to the volume of the dorsolateral prefrontal cortex (dlpfc) and hippocampus, two brain areas considered as key regions in the pathogenesis of schizophrenia. |
2012-08-10 |
2023-08-12 |
human |
| Julie M Brooks, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus permanently disrupts the mesolimbic regulation of prefrontal cholinergic transmission: implications for schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 12. 2012-08-08. PMID:21814184. |
transient inactivation of the neonatal ventral hippocampus permanently disrupts the mesolimbic regulation of prefrontal cholinergic transmission: implications for schizophrenia. |
2012-08-08 |
2023-08-12 |
rat |
| Sivan Subburaju, Francine M Bene. Induction of the GABA cell phenotype: an in vitro model for studying neurodevelopmental disorders. PloS one. vol 7. issue 3. 2012-08-03. PMID:22457755. |
recent studies of the hippocampus have suggested that a network of genes is associated with the regulation of the gad₆₇ (gad1) expression and may play a role in γ-amino butyric acid (gaba) dysfunction in schizophrenia (sz) and bipolar disorder (bd). |
2012-08-03 |
2023-08-12 |
Not clear |