| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Martinotti, G Di Iorio, S Marini, V Ricci, D De Berardis, M Di Giannantoni. Nerve growth factor and brain-derived neurotrophic factor concentrations in schizophrenia: a review. Journal of biological regulators and homeostatic agents. vol 26. issue 3. 2012-11-30. PMID:23034254. |
low serum bdnf levels were associated with reduction in hippocampal volume (hv) at the onset of schizophrenia. |
2012-11-30 |
2023-08-12 |
Not clear |
| L Lecourtier, M-C Antal, B Cosquer, A Schumacher, B Samama, M-J Angst, A Ferrandon, E Koning, J-C Cassel, A Nehli. Intact neurobehavioral development and dramatic impairments of procedural-like memory following neonatal ventral hippocampal lesion in rats. Neuroscience. vol 207. 2012-11-27. PMID:22322113. |
neonatal ventral hippocampal lesions (nvhl) in rats are considered a potent developmental model of schizophrenia. |
2012-11-27 |
2023-08-12 |
rat |
| Daniel Mamah, Michael P Harms, Deanna Barch, Martin Styner, Jeffrey A Lieberman, Lei Wan. Hippocampal shape and volume changes with antipsychotics in early stage psychotic illness. Frontiers in psychiatry. vol 3. 2012-11-20. PMID:23162479. |
progression of hippocampal shape and volume abnormalities has been described in psychotic disorders such as schizophrenia. |
2012-11-20 |
2023-08-12 |
Not clear |
| Inga H Deakin, Wiebke Nissen, Amanda J Law, Tracy Lane, Riam Kanso, Markus H Schwab, Klaus-Armin Nave, Karri P Lamsa, Ole Paulsen, David M Bannerman, Paul J Harriso. Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cerebral cortex (New York, N.Y. : 1991). vol 22. issue 7. 2012-11-13. PMID:21878485. |
it is a schizophrenia candidate gene, and hippocampal expression of the nrg1 type i isoform is increased in the disorder. |
2012-11-13 |
2023-08-12 |
mouse |
| Akira Wada, Yasuto Kunii, Keiko Ikemoto, Qiaohui Yang, Mizuki Hino, Junya Matsumoto, Shin-ichi Niw. Increased ratio of calcineurin immunoreactive neurons in the caudate nucleus of patients with schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 37. issue 1. 2012-11-08. PMID:22285318. |
there was no significant difference in the ratio of can immunoreactive (ir) neurons between schizophrenia and control groups in the dlpfc or hippocampus, and a significantly increased ratio of can-ir neurons was seen in the caudate nucleus in the brains from schizophrenia patients. |
2012-11-08 |
2023-08-12 |
human |
| Carol A Tamminga, Binu P Thomas, Ronald Chin, Perry Mihalakos, Kenneth Youens, Anthony D Wagner, Alison R Presto. Hippocampal novelty activations in schizophrenia: disease and medication effects. Schizophrenia research. vol 138. issue 2-3. 2012-10-24. PMID:22480957. |
hippocampal novelty activations in schizophrenia: disease and medication effects. |
2012-10-24 |
2023-08-12 |
Not clear |
| Carol A Tamminga, Binu P Thomas, Ronald Chin, Perry Mihalakos, Kenneth Youens, Anthony D Wagner, Alison R Presto. Hippocampal novelty activations in schizophrenia: disease and medication effects. Schizophrenia research. vol 138. issue 2-3. 2012-10-24. PMID:22480957. |
we examined hippocampal activation in schizophrenia (sz) with fmri bold in response to the presentation of novel and familiar scenes. |
2012-10-24 |
2023-08-12 |
Not clear |
| Stefan Borgwardt, Renata Smieskova, Paolo Fusar-Pol. Gray matter pathology of hippocampus - a specific endophenotype for schizophrenia? Psychiatry research. vol 202. issue 3. 2012-10-16. PMID:22743117. |
gray matter pathology of hippocampus - a specific endophenotype for schizophrenia? |
2012-10-16 |
2023-08-12 |
Not clear |
| Richard H Andersson, April Johnston, Paul A Herman, Ursula H Winzer-Serhan, Irina Karavanova, Detlef Vullhorst, André Fisahn, Andres Buonann. Neuregulin and dopamine modulation of hippocampal gamma oscillations is dependent on dopamine D4 receptors. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 32. 2012-10-15. PMID:22822214. |
the neuregulin/erbb signaling network is genetically associated with schizophrenia and modulates hippocampal γ oscillations--a type of neuronal network activity important for higher brain processes and altered in psychiatric disorders. |
2012-10-15 |
2023-08-12 |
Not clear |
| Paul R Matthews, Sharon L Eastwood, Paul J Harriso. Reduced myelin basic protein and actin-related gene expression in visual cortex in schizophrenia. PloS one. vol 7. issue 6. 2012-10-11. PMID:22675524. |
most brain gene expression studies of schizophrenia have been conducted in the frontal cortex or hippocampus. |
2012-10-11 |
2023-08-12 |
human |
| Guusje Collin, Hilleke E Hulshoff Pol, Sander V Haijma, Wiepke Cahn, René S Kahn, Martijn P van den Heuve. Impaired cerebellar functional connectivity in schizophrenia patients and their healthy siblings. Frontiers in psychiatry. vol 2. 2012-10-02. PMID:22203807. |
compared to healthy control subjects, schizophrenia patients showed impaired functional connectivity between the cerebellum and several left-sided cerebral regions, including the hippocampus, thalamus, middle cingulate gyrus, triangular part of the inferior frontal gyrus, supplementary motor area, and lingual gyrus (all p < 0.0025, whole-brain significant). |
2012-10-02 |
2023-08-12 |
human |
| Cynthia G Wibl. Hippocampal temporal-parietal junction interaction in the production of psychotic symptoms: a framework for understanding the schizophrenic syndrome. Frontiers in human neuroscience. vol 6. 2012-10-02. PMID:22737114. |
hippocampal system hyper-activity and atrophy have been consistently found in schizophrenia. |
2012-10-02 |
2023-08-12 |
Not clear |
| Peter C Williamson, John M Allma. A framework for interpreting functional networks in schizophrenia. Frontiers in human neuroscience. vol 6. 2012-10-02. PMID:22737116. |
alternatively, it is proposed that schizophrenia arises from a uniquely human brain network associated with directed effort including the dorsal anterior and posterior cingulate cortex (pcc), auditory cortex, and hippocampus while mood disorders arise from a different brain network associated with emotional encoding including the ventral anterior cingulate cortex (acc), orbital frontal cortex, and amygdala. |
2012-10-02 |
2023-08-12 |
human |
| Michael J Gandal, J Christopher Edgar, Kerstin Klook, Steven J Siege. Gamma synchrony: towards a translational biomarker for the treatment-resistant symptoms of schizophrenia. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21349276. |
such a model likely reflects hippocampal and cortical dysfunction, as well as reduced glutamatergic signaling with downstream gabaergic deficits, but is probably less influenced by dopaminergic abnormalities implicated in schizophrenia. |
2012-09-27 |
2023-08-12 |
Not clear |
| Anthony A Grac. Dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21621548. |
dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia. |
2012-09-27 |
2023-08-12 |
Not clear |
| Anthony A Grac. Dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21621548. |
convergent studies in animals and in humans have now focused on the hippocampus as a central component in the generation of psychosis and possibly other symptom states in schizophrenia. |
2012-09-27 |
2023-08-12 |
Not clear |
| Anthony A Grac. Dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21621548. |
therapeutic approaches that focus on normalizing hippocampal function may prove to be more effective treatment avenues for the schizophrenia patient. |
2012-09-27 |
2023-08-12 |
Not clear |
| Thomas M Sanderson, Marie-Caroline Cotel, Michael J O'Neill, Mark D Tricklebank, Graham L Collingridge, Emanuele She. Alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia. Neuropharmacology. vol 62. issue 3. 2012-09-27. PMID:21854789. |
alterations in hippocampal excitability, synaptic transmission and synaptic plasticity in a neurodevelopmental model of schizophrenia. |
2012-09-27 |
2023-08-12 |
rat |
| Kenkichi Takase, Yasuhiro Yamamoto, Tatsurou Yagam. Maternal deprivation in the middle of a stress hyporesponsive period decreases hippocampal calcineurin expression and causes abnormal social and cognitive behaviours in adult male Wistar rats: relevance to negative symptoms of schizophrenia. Behavioural brain research. vol 232. issue 1. 2012-09-27. PMID:22543011. |
maternal deprivation in the middle of a stress hyporesponsive period decreases hippocampal calcineurin expression and causes abnormal social and cognitive behaviours in adult male wistar rats: relevance to negative symptoms of schizophrenia. |
2012-09-27 |
2023-08-12 |
human |
| Ketan Marballi, Dianne Cruz, Peter Thompson, Consuelo Walss-Bas. Differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings. PloS one. vol 7. issue 5. 2012-09-19. PMID:22590542. |
differential neuregulin 1 cleavage in the prefrontal cortex and hippocampus in schizophrenia and bipolar disorder: preliminary findings. |
2012-09-19 |
2023-08-12 |
mouse |