| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kühn, F Musso, A Mobascher, T Warbrick, G Winterer, J Gallina. Hippocampal subfields predict positive symptoms in schizophrenia: first evidence from brain morphometry. Translational psychiatry. vol 2. 2013-03-14. PMID:22692142. |
alterations of hippocampal anatomy have been reported consistently in schizophrenia. |
2013-03-14 |
2023-08-12 |
Not clear |
| S Kühn, F Musso, A Mobascher, T Warbrick, G Winterer, J Gallina. Hippocampal subfields predict positive symptoms in schizophrenia: first evidence from brain morphometry. Translational psychiatry. vol 2. 2013-03-14. PMID:22692142. |
our observation opens the gate for advanced investigation of the commonly reported hippocampal abnormalities in schizophrenia in terms of specific subfields. |
2013-03-14 |
2023-08-12 |
Not clear |
| Stefan Busse, Mandy Busse, Kolja Schiltz, Hendrik Bielau, Tomasz Gos, Ralf Brisch, Christian Mawrin, Andrea Schmitt, Wolfgang Jordan, Ulf J Müller, Hans-Gert Bernstein, Bernhard Bogerts, Johann Steine. Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations? Brain, behavior, and immunity. vol 26. issue 8. 2013-03-12. PMID:22917959. |
different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations? |
2013-03-12 |
2023-08-12 |
Not clear |
| Stefan Busse, Mandy Busse, Kolja Schiltz, Hendrik Bielau, Tomasz Gos, Ralf Brisch, Christian Mawrin, Andrea Schmitt, Wolfgang Jordan, Ulf J Müller, Hans-Gert Bernstein, Bernhard Bogerts, Johann Steine. Different distribution patterns of lymphocytes and microglia in the hippocampus of patients with residual versus paranoid schizophrenia: further evidence for disease course-related immune alterations? Brain, behavior, and immunity. vol 26. issue 8. 2013-03-12. PMID:22917959. |
based on these neuroinflammatory hypotheses, we have quantified the numerical density of immunostained cd3+ t-lymphocytes, cd20+ b-lymphocytes, and hla-dr+ microglial cells in the posterior hippocampus of 17 schizophrenia patients and 11 matched controls. |
2013-03-12 |
2023-08-12 |
Not clear |
| Julie M Brooks, Michelle L Pershing, Morten S Thomsen, Jens D Mikkelsen, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22781844. |
cognitive deficits represent a core symptom cluster in schizophrenia that are thought to reflect developmental dysregulations within a neural system involving the ventral hippocampus (vh), nucleus accumbens (nac), and prefrontal cortex (pfc). |
2013-02-26 |
2023-08-12 |
rat |
| Julie M Brooks, Michelle L Pershing, Morten S Thomsen, Jens D Mikkelsen, Martin Sarter, John P Brun. Transient inactivation of the neonatal ventral hippocampus impairs attentional set-shifting behavior: reversal with an α7 nicotinic agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 11. 2013-02-26. PMID:22781844. |
given that patients with schizophrenia exhibit hippocampal pathophysiology and deficits in the ed stages of set-shifting tasks, our results support the significance of transient hippocampal inactivation as an animal model for studying the cognitive impairments in schizophrenia as well as the pro-cognitive therapeutic potential of α7 nachr agonists. |
2013-02-26 |
2023-08-12 |
rat |
| Neal R Swerdlow, Gregory A Light, Michelle R Breier, Jody M Shoemaker, Richard L Saint Marie, Alaina C Neary, Mark A Geyer, Karen E Stevens, Susan B Powel. Sensory and sensorimotor gating deficits after neonatal ventral hippocampal lesions in rats. Developmental neuroscience. vol 34. issue 2-3. 2013-02-22. PMID:22572564. |
neonatal ventral hippocampal lesions (nvhls) in rats lead to reduced prepulse inhibition (ppi) of startle and other behavioral deficits in adulthood that model abnormalities in schizophrenia patients. |
2013-02-22 |
2023-08-12 |
rat |
| Xing-Shi Chen, Chen Zhang, Yi-Feng Xu, Ming-Dao Zhang, Fei-Ying Lou, Chong Chen, Jin Tan. Neonatal ventral hippocampal lesion as a valid model of schizophrenia: evidence from sensory gating study. Chinese medical journal. vol 125. issue 15. 2013-02-13. PMID:22931986. |
neonatal ventral hippocampal lesion as a valid model of schizophrenia: evidence from sensory gating study. |
2013-02-13 |
2023-08-12 |
rat |
| Xing-Shi Chen, Chen Zhang, Yi-Feng Xu, Ming-Dao Zhang, Fei-Ying Lou, Chong Chen, Jin Tan. Neonatal ventral hippocampal lesion as a valid model of schizophrenia: evidence from sensory gating study. Chinese medical journal. vol 125. issue 15. 2013-02-13. PMID:22931986. |
the neonatal ventral hippocampal lesion (nvhl) rat model has been proposed as an experimental model for schizophrenia. |
2013-02-13 |
2023-08-12 |
rat |
| Faith M Hanlon, Jon M Houck, Stefan D Klimaj, Arvind Caprihan, Andrew R Mayer, Michael P Weisend, Juan R Bustillo, Derek A Hamilton, Claudia D Tesch. Frontotemporal anatomical connectivity and working-relational memory performance predict everyday functioning in schizophrenia. Psychophysiology. vol 49. issue 10. 2013-02-12. PMID:22882287. |
hippocampal (relational memory) and prefrontal cortex (pfc; working memory) impairments have been found in patients with schizophrenia (sp), possibly due to a dysfunctional connection between structures. |
2013-02-12 |
2023-08-12 |
human |
| Carol A Tamminga, Sarah Southcott, Carolyn Sacco, Anthony D Wagner, Subroto Ghos. Glutamate dysfunction in hippocampus: relevance of dentate gyrus and CA3 signaling. Schizophrenia bulletin. vol 38. issue 5. 2013-02-04. PMID:22532703. |
hippocampal imaging studies in schizophrenia have identified 2 alterations in mtl--increases in baseline blood perfusion and decreases in task-related activation. |
2013-02-04 |
2023-08-12 |
Not clear |
| Carol A Tamminga, Sarah Southcott, Carolyn Sacco, Anthony D Wagner, Subroto Ghos. Glutamate dysfunction in hippocampus: relevance of dentate gyrus and CA3 signaling. Schizophrenia bulletin. vol 38. issue 5. 2013-02-04. PMID:22532703. |
these observations along with converging postsynaptic hippocampal protein changes suggest that homeostatic plasticity mechanisms might be altered in schizophrenia hippocampus. |
2013-02-04 |
2023-08-12 |
Not clear |
| H Ozdemir, A Ertugrul, K Basar, E Sak. Differential effects of antipsychotics on hippocampal presynaptic protein expressions and recognition memory in a schizophrenia model in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 39. issue 1. 2013-01-21. PMID:22640753. |
differential effects of antipsychotics on hippocampal presynaptic protein expressions and recognition memory in a schizophrenia model in mice. |
2013-01-21 |
2023-08-12 |
mouse |
| Nathan L Hutcheson, Meredith A Reid, David M White, Nina V Kraguljac, Kathy B Avsar, Mark S Bolding, Robert C Knowlton, Jan A den Hollander, Adrienne C Laht. Multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging. Schizophrenia research. vol 140. issue 1-3. 2013-01-18. PMID:22831772. |
multimodal analysis of the hippocampus in schizophrenia using proton magnetic resonance spectroscopy and functional magnetic resonance imaging. |
2013-01-18 |
2023-08-12 |
Not clear |
| Keith G Phillips, Ullrich Bartsch, Andrew P McCarthy, Dale M Edgar, Mark D Tricklebank, Keith A Wafford, Matt W Jone. Decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia. Neuron. vol 76. issue 3. 2013-01-11. PMID:23141065. |
decoupling of sleep-dependent cortical and hippocampal interactions in a neurodevelopmental model of schizophrenia. |
2013-01-11 |
2023-08-12 |
rat |
| Francine M Bene. Nicotinic receptors and functional regulation of GABA cell microcircuitry in bipolar disorder and schizophrenia. Handbook of experimental pharmacology. issue 213. 2013-01-10. PMID:23027422. |
studies of the hippocampus in postmortem brains from patients with schizophrenia and bipolar disorder have provided evidence for a defect of gabaergic interneurons. |
2013-01-10 |
2023-08-12 |
Not clear |
| Ammar Kutiyanawalla, Wanwisa Promsote, Alvin Terry, Anilkumar Pilla. Cysteamine treatment ameliorates alterations in GAD67 expression and spatial memory in heterozygous reeler mice. The international journal of neuropsychopharmacology. vol 15. issue 8. 2012-12-28. PMID:21777509. |
interestingly, heterozygous reeler mice (hrm) have decreased gad67 expression in the frontal cortex and hippocampus and they exhibit many behavioural and neurochemical abnormalities similar to schizophrenia. |
2012-12-28 |
2023-08-12 |
mouse |
| S K Bhardwaj, P A Forcelli, G Palchik, K Gale, L K Srivastava, A Kondratye. Neonatal exposure to phenobarbital potentiates schizophrenia-like behavioral outcomes in the rat. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22366076. |
thus, in this study, we examined the effects of a single acute neonatal exposure to phenobarbital on adult behavioral outcomes in the rat neonatal ventral hippocampal (nvh) lesion model of schizophrenia. |
2012-12-20 |
2023-08-12 |
rat |
| T Wobrock, A Hasan, P Falka. Innovative treatment approaches in schizophrenia enhancing neuroplasticity: aerobic exercise, erythropoetin and repetitive transcranial magnetic stimulation. Current pharmaceutical biotechnology. vol 13. issue 8. 2012-12-18. PMID:22283764. |
out of these interventions aerobic exercise has been shown to increase hippocampal volume, elevate n-acetyl-aspartate in the hippocampus as neuronal marker, and improve short-term memory in schizophrenia. |
2012-12-18 |
2023-08-12 |
Not clear |
| Snezana Kusljic, Maarten Van Den Buus. Differential role of serotonin projections from the dorsal and median raphe nuclei in phencyclidine-induced hyperlocomotion and fos-like immunoreactivity in rats. Synapse (New York, N.Y.). vol 66. issue 10. 2012-11-30. PMID:22733588. |
these results support our previous studies suggesting a role of serotonergic projections from the mrn to the dorsal hippocampus in some of the symptoms of schizophrenia. |
2012-11-30 |
2023-08-12 |
rat |