| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karla Becerril, Deanna Barc. Influence of emotional processing on working memory in schizophrenia. Schizophrenia bulletin. vol 37. issue 5. 2012-01-17. PMID:20176860. |
individuals with schizophrenia showed intact amygdala activity in response to emotionally evocative stimuli, but demonstrated altered dorsolateral prefrontal cortex (dlpfc) and hippocampal activity while performing an emotionally loaded wm-task. |
2012-01-17 |
2023-08-12 |
human |
| Faith M Hanlon, Jon M Houck, Clinton J Pyeatt, S Laura Lundy, Matthew J Euler, Michael P Weisend, Robert J Thoma, Juan R Bustillo, Gregory A Miller, Claudia D Tesch. Bilateral hippocampal dysfunction in schizophrenia. NeuroImage. vol 58. issue 4. 2012-01-06. PMID:21763438. |
bilateral hippocampal dysfunction in schizophrenia. |
2012-01-06 |
2023-08-12 |
human |
| Faith M Hanlon, Jon M Houck, Clinton J Pyeatt, S Laura Lundy, Matthew J Euler, Michael P Weisend, Robert J Thoma, Juan R Bustillo, Gregory A Miller, Claudia D Tesch. Bilateral hippocampal dysfunction in schizophrenia. NeuroImage. vol 58. issue 4. 2012-01-06. PMID:21763438. |
schizophrenia patients were evaluated to determine whether they exhibited a lateralized hippocampal deficit. |
2012-01-06 |
2023-08-12 |
human |
| Faith M Hanlon, Jon M Houck, Clinton J Pyeatt, S Laura Lundy, Matthew J Euler, Michael P Weisend, Robert J Thoma, Juan R Bustillo, Gregory A Miller, Claudia D Tesch. Bilateral hippocampal dysfunction in schizophrenia. NeuroImage. vol 58. issue 4. 2012-01-06. PMID:21763438. |
these data demonstrate the capacity to assess lateralized hippocampal function and suggest a bilateral hippocampal behavioral and activation deficit in schizophrenia. |
2012-01-06 |
2023-08-12 |
human |
| T Panigada, R-D Gosseli. Behavioural alteration in chronic pain: are brain glia involved? Medical hypotheses. vol 77. issue 4. 2011-12-29. PMID:21741179. |
indeed, in mood disorders (unipolar depression, anxiety disorders, autism or schizophrenia) glial changes in brain regions involved in mood control (prefrontal and cingulate cortices, amygdala and the hippocampus) have been recurrently described. |
2011-12-29 |
2023-08-12 |
Not clear |
| Matthew J Smith, Lei Wang, Will Cronenwett, Morris B Goldman, Daniel Mamah, Deanna M Barch, John G Csernansk. Alcohol use disorders contribute to hippocampal and subcortical shape differences in schizophrenia. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21658914. |
alcohol use disorders contribute to hippocampal and subcortical shape differences in schizophrenia. |
2011-12-23 |
2023-08-12 |
Not clear |
| Aristides A Capizzano, Juana L Nicoll Toscano, Beng-Choon H. Magnetic resonance spectroscopy of limbic structures displays metabolite differences in young unaffected relatives of schizophrenia probands. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21705196. |
imaging studies of schizophrenia patients showed fronto-temporal brain volume deficits, while magnetic resonance spectroscopy (mrs) studies of patients and unaffected biological relatives have found a decrement of the neuronal marker n-acetyl-aspartate (naa) in the hippocampus and frontal lobes, and increased choline-containing phospholipids. |
2011-12-23 |
2023-08-12 |
Not clear |
| Aristides A Capizzano, Juana L Nicoll Toscano, Beng-Choon H. Magnetic resonance spectroscopy of limbic structures displays metabolite differences in young unaffected relatives of schizophrenia probands. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21705196. |
using a 3t mr scanner, we determined the metabolite profile within limbic regions (anterior cingulate cortex (acc) and left hippocampus) of 36 unaffected, adolescent/young adult relatives of schizophrenia probands (first-degree=16, second-degree=20) and 25 healthy controls with no family history of schizophrenia. |
2011-12-23 |
2023-08-12 |
Not clear |
| Christine Konradi, C Kevin Yang, Eric I Zimmerman, Kathryn M Lohmann, Paul Gresch, Harry Pantazopoulos, Sabina Berretta, Stephan Hecker. Hippocampal interneurons are abnormal in schizophrenia. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21745723. |
hippocampal interneurons are abnormal in schizophrenia. |
2011-12-23 |
2023-08-12 |
Not clear |
| Christine Konradi, C Kevin Yang, Eric I Zimmerman, Kathryn M Lohmann, Paul Gresch, Harry Pantazopoulos, Sabina Berretta, Stephan Hecker. Hippocampal interneurons are abnormal in schizophrenia. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21745723. |
the cellular substrate of hippocampal dysfunction in schizophrenia remains unknown. |
2011-12-23 |
2023-08-12 |
Not clear |
| Daniel J Lodge, Anthony A Grac. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends in pharmacological sciences. vol 32. issue 9. 2011-12-14. PMID:21700346. |
hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. |
2011-12-14 |
2023-08-12 |
Not clear |
| Daniel J Lodge, Anthony A Grac. Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends in pharmacological sciences. vol 32. issue 9. 2011-12-14. PMID:21700346. |
enhanced hippocampal activity has been reported in preclinical models and in schizophrenia patients. |
2011-12-14 |
2023-08-12 |
Not clear |
| Liam J Drew, Kimberly L Stark, Karine Fénelon, Maria Karayiorgou, Amy B Macdermott, Joseph A Gogo. Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion. Molecular and cellular neurosciences. vol 47. issue 4. 2011-12-06. PMID:21635953. |
the hippocampus has been implicated in schizophrenia pathogenesis, is reduced in volume in 22q11.2 deletion carriers and displays altered neuronal structure in a mouse model of the mutation (df(16)a(+/-) mice). |
2011-12-06 |
2023-08-12 |
mouse |
| Liam J Drew, Kimberly L Stark, Karine Fénelon, Maria Karayiorgou, Amy B Macdermott, Joseph A Gogo. Evidence for altered hippocampal function in a mouse model of the human 22q11.2 microdeletion. Molecular and cellular neurosciences. vol 47. issue 4. 2011-12-06. PMID:21635953. |
overall, experiments performed in this 22q11.2 deletion model demonstrated deficits of various degrees across different regions of the hippocampus, which together may contribute to the increased risk of developing schizophrenia. |
2011-12-06 |
2023-08-12 |
mouse |
| Noriko Takashima, Yuri S Odaka, Kazuto Sakoori, Takumi Akagi, Tsutomu Hashikawa, Naoko Morimura, Kazuyuki Yamada, Jun Arug. Impaired cognitive function and altered hippocampal synapse morphology in mice lacking Lrrtm1, a gene associated with schizophrenia. PloS one. vol 6. issue 7. 2011-12-06. PMID:21818371. |
impaired cognitive function and altered hippocampal synapse morphology in mice lacking lrrtm1, a gene associated with schizophrenia. |
2011-12-06 |
2023-08-12 |
mouse |
| Gregory G Brown, Jun-Seok Lee, Irina A Strigo, Michael P Caligiuri, M J Meloy, James Loh. Voxel-based morphometry of patients with schizophrenia or bipolar I disorder: a matched control study. Psychiatry research. vol 194. issue 2. 2011-12-06. PMID:21924872. |
two recent meta-analyses have reported that gray matter volumes of schizophrenia and bipolar i patients differ in the amygdala, hippocampus, or perigenual anterior cingulate. |
2011-12-06 |
2023-08-12 |
human |
| Gregory G Brown, Jun-Seok Lee, Irina A Strigo, Michael P Caligiuri, M J Meloy, James Loh. Voxel-based morphometry of patients with schizophrenia or bipolar I disorder: a matched control study. Psychiatry research. vol 194. issue 2. 2011-12-06. PMID:21924872. |
region of interest analyses found moderately large to large differences between schizophrenia and healthy subjects in the amygdala and hippocampus. |
2011-12-06 |
2023-08-12 |
human |
| Gregory G Brown, Jun-Seok Lee, Irina A Strigo, Michael P Caligiuri, M J Meloy, James Loh. Voxel-based morphometry of patients with schizophrenia or bipolar I disorder: a matched control study. Psychiatry research. vol 194. issue 2. 2011-12-06. PMID:21924872. |
when schizophrenia and bipolar groups were directly compared, the schizophrenia group showed smaller gray matter volumes in right subcortical regions involving the right hippocampus, putamen, and amygdala. |
2011-12-06 |
2023-08-12 |
human |
| David Freedman, Raymond Deicken, Lawrence S Kegeles, Sophia Vinogradov, Yuanyuan Bao, Alan S Brow. Maternal-fetal blood incompatibility and neuromorphologic anomalies in schizophrenia: Preliminary findings. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 6. 2011-11-29. PMID:21570439. |
the findings also suggest that the larger hippocampal volume in exposed controls may indicate a mechanism of adaptive resilience which diminishes the risk that controls will develop schizophrenia. |
2011-11-29 |
2023-08-12 |
Not clear |
| Emmanuel Kostakis, Ming-Kuei Jang, Shelley J Russek, Terrell T Gibbs, David H Far. A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons. Journal of neurochemistry. vol 119. issue 3. 2011-11-29. PMID:21883211. |
the neuroactive steroid pregnenolone sulfate (ps) acts as a cognitive enhancer in impaired animals, augments ltp in hippocampal slices by enhancing nmdar activity, and may participate in the reduction of schizophrenia's negative symptoms by systemic pregnenolone. |
2011-11-29 |
2023-08-12 |
Not clear |