| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniela Gerovska, Marcos J Araúzo-Brav. The common incidence-age multistep model of neurodegenerative diseases revisited: wider general age range of incidence corresponds to fewer disease steps. Cell & bioscience. vol 12. issue 1. 2022-01-30. PMID:35093175. |
previously, we collected age-stratified incidence data of 404 epidemiological datasets of 10 neurodegenerative diseases (nds), namely amyotrophic lateral sclerosis (als), alzheimer's disease (ad), parkinson's disease (pd), huntington's disease (hd), fronto temporal dementia (ftd), dementia with lewy bodies (dlb), parkinsonism (pdm), parkinson's disease with dementia (pdd), creutzfeldt-jakob disease (cjd), and multiple sclerosis (ms). |
2022-01-30 |
2023-08-13 |
Not clear |
| Amina Nasri, Ikram Sghaier, Alya Gharbi, Saloua Mrabet, Mouna Ben Djebara, Amina Gargouri, Imen Kacem, Riadh Gouide. Role of Apolipoprotein E in the Clinical Profile of Atypical Parkinsonian Syndromes. Alzheimer disease and associated disorders. 2022-01-10. PMID:35001031. |
atypical parkinsonian syndromes (aps) encompass a spectrum of neurodegenerative diseases including dementia with lewy bodies (dlb), progressive supranuclear palsy (psp), multiple system atrophy (msa), and corticobasal syndrome (cbs). |
2022-01-10 |
2023-08-13 |
Not clear |
| Haitao Tu, Zhi Wei Zhang, Lifeng Qiu, Yuning Lin, Mei Jiang, Sook-Yoong Chia, Yanfei Wei, Adeline S L Ng, Richard Reynolds, Eng-King Tan, Li Zen. Increased expression of pathological markers in Parkinson's disease dementia post-mortem brains compared to dementia with Lewy bodies. BMC neuroscience. vol 23. issue 1. 2022-01-05. PMID:34983390. |
parkinson's disease (pd) and dementia with lewy bodies (dlb) are common age-related neurodegenerative diseases comprising lewy body spectrum disorders associated with cortical and subcortical lewy body pathology. |
2022-01-05 |
2023-08-13 |
Not clear |
| Lisa Fellner, Elisa Gabassi, Johannes Haybaeck, Frank Edenhofe. Autophagy in α-Synucleinopathies-An Overstrained System. Cells. vol 10. issue 11. 2021-12-08. PMID:34831366. |
alpha-synucleinopathies comprise progressive neurodegenerative diseases, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2021-12-08 |
2023-08-13 |
Not clear |
| Sven J van der Lee, Inger van Steenoven, Marleen van de Beek, Niccolò Tesi, Iris E Jansen, Natasja M van Schoor, Marcel J T Reinders, Martijn Huisman, Philip Scheltens, Charlotte E Teunissen, Henne Holstege, Wiesje M van der Flier, Afina W Lemstr. Genetics Contributes to Concomitant Pathology and Clinical Presentation in Dementia with Lewy Bodies. Journal of Alzheimer's disease : JAD. vol 83. issue 1. 2021-11-26. PMID:34308904. |
dementia with lewy bodies (dlb) is a complex, progressive neurodegenerative disease with considerable phenotypic, pathological, and genetic heterogeneity. |
2021-11-26 |
2023-08-13 |
Not clear |
| Antoine Brangier, Nathalie Jomard, Alice Duvivier, Claire Paquet, Frédéric Blan. [Assessment of the knowledge of Lewy body disease by health care professionnels compared to Alzheimer's disease: result of a descriptive analytical study]. Geriatrie et psychologie neuropsychiatrie du vieillissement. vol 19. issue 3. 2021-11-25. PMID:34405805. |
dementia with lewy body (dlb) is a common neurodegenerative disease that warrants specific care, which remains largely underdiagnosed. |
2021-11-25 |
2023-08-13 |
Not clear |
| Keita Sakurai, Daita Kaneda, Yuto Uchida, Shohei Inui, Masahiko Bundo, Akio Akagi, Takashi Nihashi, Yasuyuki Kimura, Takashi Kato, Kengo Ito, Wataru Ohashi, Yoshio Hashizum. Can Medial Temporal Impairment Be an Imaging Red Flag for Neurodegeneration in Disproportionately Enlarged Subarachnoid Space Hydrocephalus? Journal of Alzheimer's disease : JAD. vol 83. issue 3. 2021-11-19. PMID:34420966. |
the differentiation of idiopathic normal pressure hydrocephalus (inph) from neurodegenerative diseases such as alzheimer's disease (ad) and dementia with lewy bodies (dlb) is often challenging because of their non-specific symptoms. |
2021-11-19 |
2023-08-13 |
Not clear |
| Surabhi Mehra, Laxmikant Gadhe, Riya Bera, Ajay Singh Sawner, Samir K Maj. Structural and Functional Insights into α-Synuclein Fibril Polymorphism. Biomolecules. vol 11. issue 10. 2021-11-08. PMID:34680054. |
abnormal accumulation of aggregated α-synuclein (α-syn) is seen in a variety of neurodegenerative diseases, including parkinson's disease (pd), multiple system atrophy (msa), dementia with lewy body (dlb), parkinson's disease dementia (pdd), and even subsets of alzheimer's disease (ad) showing lewy-body-like pathology. |
2021-11-08 |
2023-08-13 |
Not clear |
| Dariusz Koziorowski, Monika Figura, Łukasz M Milanowski, Stanisław Szlufik, Piotr Alster, Natalia Madetko, Andrzej Friedma. Mechanisms of Neurodegeneration in Various Forms of Parkinsonism-Similarities and Differences. Cells. vol 10. issue 3. 2021-10-18. PMID:33809527. |
parkinson's disease (pd), dementia with lewy body (dlb), progressive supranuclear palsy (psp), corticobasal degeneration (cbd) and multiple system atrophy (msa) belong to a group of neurodegenerative diseases called parkinsonian syndromes. |
2021-10-18 |
2023-08-13 |
Not clear |
| Ito Kawakami, Atsuko Motoda, Masashi Hashimoto, Aki Shimozawa, Masami Masuda-Suzukake, Reiko Ohtani, Mina Takase, Mari Kumashiro, Kazuyuki Samejima, Masato Hasegaw. Progression of phosphorylated α-synuclein in Macaca fuscata. Brain pathology (Zurich, Switzerland). vol 31. issue 5. 2021-10-13. PMID:33754430. |
prion-like spreading of abnormal proteins is proposed to occur in neurodegenerative diseases, and the progression of α-synuclein (α-syn) deposits has been reported in the brains of animal models injected with synthetic α-syn fibrils or pathological α-syn prepared from patients with parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2021-10-13 |
2023-08-13 |
human |
| Sezgi Canaslan, Matthias Schmitz, Anna Villar-Piqué, Fabian Maass, Karin Gmitterová, Daniela Varges, Paul Lingor, Franc Llorens, Peter Hermann, Inga Zer. Detection of Cerebrospinal Fluid Neurofilament Light Chain as a Marker for Alpha-Synucleinopathies. Frontiers in aging neuroscience. vol 13. 2021-10-12. PMID:34630068. |
alpha-synucleinopathies, such as parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa), are a class of neurodegenerative diseases. |
2021-10-12 |
2023-08-13 |
Not clear |
| Sofia Lövestam, Manuel Schweighauser, Tomoyasu Matsubara, Shigeo Murayama, Taisuke Tomita, Takashi Ando, Kazuko Hasegawa, Mari Yoshida, Airi Tarutani, Masato Hasegawa, Michel Goedert, Sjors H W Schere. Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy. FEBS open bio. vol 11. issue 4. 2021-10-06. PMID:33548114. |
seeded assembly of α-synuclein into filaments is believed to underlie the prion-like spreading of protein inclusions in a number of human neurodegenerative diseases, including parkinson's disease, dementia with lewy bodies (dlb) and multiple system atrophy (msa). |
2021-10-06 |
2023-08-13 |
human |
| Sumeyya Akyol, Ali Yilmaz, Kyung Joon Oh, Zafer Ugur, Buket Aydas, Bernadette McGuinness, Peter Passmore, Patrick G Kehoe, Michael Maddens, Brian D Green, Stewart F Graha. Evidence that the Kennedy and polyamine pathways are dysregulated in human brain in cases of dementia with Lewy bodies. Brain research. vol 1743. 2021-10-04. PMID:32450077. |
dlb is less well known than other neurodegenerative diseases such as alzheimer's and parkinson's disease which is perhaps why it is under-investigated. |
2021-10-04 |
2023-08-13 |
human |
| Rahel Feleke, Regina H Reynolds, Amy M Smith, Bension Tilley, Sarah A Gagliano Taliun, John Hardy, Paul M Matthews, Steve Gentleman, David R Owen, Michael R Johnson, Prashant K Srivastava, Mina Ryte. Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases. Acta neuropathologica. vol 142. issue 3. 2021-09-09. PMID:34309761. |
parkinson's disease (pd), parkinson's disease with dementia (pdd) and dementia with lewy bodies (dlb) are three clinically, genetically and neuropathologically overlapping neurodegenerative diseases collectively known as the lewy body diseases (lbds). |
2021-09-09 |
2023-08-13 |
Not clear |
| Rahel Feleke, Regina H Reynolds, Amy M Smith, Bension Tilley, Sarah A Gagliano Taliun, John Hardy, Paul M Matthews, Steve Gentleman, David R Owen, Michael R Johnson, Prashant K Srivastava, Mina Ryte. Cross-platform transcriptional profiling identifies common and distinct molecular pathologies in Lewy body diseases. Acta neuropathologica. vol 142. issue 3. 2021-09-09. PMID:34309761. |
using this approach, we (i) found transcriptional alterations in multiple cell types across the lbds; (ii) discovered evidence for widespread dysregulation of rna splicing, particularly in pdd and dlb; (iii) identified potential splicing factors, with links to other dementia-related neurodegenerative diseases, coordinating this dysregulation; and (iv) identified transcriptomic commonalities and distinctions between the lbds that inform understanding of the relationships between these three clinical disorders. |
2021-09-09 |
2023-08-13 |
Not clear |
| Karan Sharma, Surabhi Mehra, Ajay S Sawner, Pratap S Markam, Rajlaxmi Panigrahi, Ambuja Navalkar, Debdeep Chatterjee, Rakesh Kumar, Pradeep Kadu, Komal Patel, Soumik Ray, Ashutosh Kumar, Samir K Maj. Effect of Disease-Associated P123H and V70M Mutations on β-Synuclein Fibrillation. ACS chemical neuroscience. vol 11. issue 18. 2021-06-18. PMID:32833434. |
synucleinopathies are a class of neurodegenerative diseases, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2021-06-18 |
2023-08-13 |
Not clear |
| Taku Homma, Shuta Toru, Katsuiku Hirokawa, Toshiki Uchihar. Digital mapping of Lewy bodies and neurites in alpha-synuclein stained large cerebral hemispheric sections from three patients with dementia with Lewy bodies showing psychotic manifestations: A pilot study. Neuroscience letters. vol 747. 2021-06-03. PMID:33548407. |
dementia with lewy bodies (dlb) is one of the major neurodegenerative diseases and a clinical diagnosis is made based on the fourth consensus report on dlb. |
2021-06-03 |
2023-08-13 |
Not clear |
| Michiyo Iba, Changyoun Kim, Michelle Sallin, Somin Kwon, Anjali Verma, Cassia Overk, Robert A Rissman, Ranjan Sen, Jyoti Misra Sen, Eliezer Maslia. Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models. Journal of neuroinflammation. vol 17. issue 1. 2021-05-24. PMID:32680537. |
α-synuclein (α-syn) is a pre-synaptic protein which progressively accumulates in neuronal and non-neuronal cells in neurodegenerative diseases such as parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy. |
2021-05-24 |
2023-08-13 |
Not clear |
| Dylan Torboli, Giovanna Mioni, Cinzia Bussé, Annachiara Cagnin, Antonino Valles. Subjective experience of time in dementia with Lewy bodies during COVID-19 lockdown. Current psychology (New Brunswick, N.J.). 2021-05-18. PMID:33994757. |
dementia with lewy bodies (dlb) is a neurodegenerative disease characterized by cognitive, behavioral and motor symptoms and has a more challenging clinical management and poorer prognosis compared to other forms of dementia. |
2021-05-18 |
2023-08-13 |
Not clear |
| Andrei Surgucho. Analysis of Protein Conformational Strains-A Key for New Diagnostic Methods of Human Diseases. International journal of molecular sciences. vol 21. issue 8. 2021-01-18. PMID:32316500. |
it is associated with several neurodegenerative diseases, including parkinson's disease (pd), dementia with lewy bodies (dlb), and multiple system atrophy (msa). |
2021-01-18 |
2023-08-13 |
human |