| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seyed Saman Nemati, Leila Sadeghi, Gholamreza Dehghan, Nader Sheiban. Lateralization of the hippocampus: A review of molecular, functional, and physiological properties in health and disease. Behavioural brain research. 2023-09-08. PMID:37683813. |
the hippocampus is very important in cognitive disorders, related to seizures and dementia, such as epilepsy and alzheimer's disease. |
2023-09-08 |
2023-10-07 |
Not clear |
| Enya Paschen, Piret Kleis, Diego M Vieira, Katharina Heining, Christian Boehler, Ulrich Egert, Ute Häussler, Carola A Haa. On-demand low-frequency stimulation for seizure control: efficacy and behavioural implications. Brain : a journal of neurology. 2023-09-07. PMID:37675644. |
mesial temporal lobe epilepsy (mtle), the most common form of focal epilepsy in adults, is often refractory to medication and associated with hippocampal sclerosis. |
2023-09-07 |
2023-10-07 |
mouse |
| Enya Paschen, Piret Kleis, Diego M Vieira, Katharina Heining, Christian Boehler, Ulrich Egert, Ute Häussler, Carola A Haa. On-demand low-frequency stimulation for seizure control: efficacy and behavioural implications. Brain : a journal of neurology. 2023-09-07. PMID:37675644. |
in preclinical epilepsy models, hippocampal lfs successfully prevented seizures when applied continuously. |
2023-09-07 |
2023-10-07 |
mouse |
| Caroline Reindl, Katrin Walther, Anna-Lena Allgäuer, Johannes D Lang, Tamara M Welte, Jenny Stritzelberger, Stephanie Gollwitzer, Michael Schwarz, Regina Trollmann, Dominik Madzar, Michael Knott, Arnd Doerfler, Frank Seifert, Karl Rössler, Sebastian Brandner, Stefan Rampp, Stefan Schwab, Hajo M Hame. Age of epilepsy onset as modulating factor for naming deficit after epilepsy surgery: a voxel-based lesion-symptom mapping study. Scientific reports. vol 13. issue 1. 2023-09-01. PMID:37658152. |
for late epilepsy onset, the temporomesial expansion also included the left hippocampus. |
2023-09-01 |
2023-09-07 |
Not clear |
| Caroline Reindl, Katrin Walther, Anna-Lena Allgäuer, Johannes D Lang, Tamara M Welte, Jenny Stritzelberger, Stephanie Gollwitzer, Michael Schwarz, Regina Trollmann, Dominik Madzar, Michael Knott, Arnd Doerfler, Frank Seifert, Karl Rössler, Sebastian Brandner, Stefan Rampp, Stefan Schwab, Hajo M Hame. Age of epilepsy onset as modulating factor for naming deficit after epilepsy surgery: a voxel-based lesion-symptom mapping study. Scientific reports. vol 13. issue 1. 2023-09-01. PMID:37658152. |
for later age of epilepsy onset, the extent of the area at risk of postoperative naming deficit at 6 months after surgery included an increasing left temporobasal area which finally also comprised the hippocampus. |
2023-09-01 |
2023-09-07 |
Not clear |
| Sayed Mostafa Modarres Mousavi, Fatemeh Alipour, Farshid Noorbakhsh, Maryam Jafarian, Masoud Ghadipasha, Jaber Gharehdaghi, Christoph Kellinghaus, Erwin-Josef Speckmann, Walter Stummer, Maryam Khaleghi Ghadiri, Ali Gorj. Clinical Correlation of Altered Molecular Signatures in Epileptic Human Hippocampus and Amygdala. Molecular neurobiology. 2023-09-01. PMID:37658249. |
our findings revealed significant and complex changes in the expression of several key regulatory genes in both the hippocampus and amygdala of patients with intractable epilepsy. |
2023-09-01 |
2023-09-07 |
human |
| Robert E Blair, Elisa Hawkins, Lauren R Pinchbeck, Robert J DeLorenzo, Laxmikant S Deshpand. The Journal of pharmacology and experimental therapeutics. 2023-08-29. PMID:37643794. |
this study demonstrates that op-induced se is associated with hippocampal neuronal loss, extensive mfs, and the development of srs, all hallmarks of chronic epilepsy. |
2023-08-29 |
2023-09-07 |
rat |
| Xueqi Liu, Yunyan Zhao, Xiaoshan Liang, Yuewen Ding, Jiao Hu, Ning Deng, Yiting Zhao, Ping Huang, Wei Xi. In Vivo Evaluation of Self-assembled nano-Saikosaponin-a for Epilepsy Treatment. Molecular biotechnology. 2023-08-22. PMID:37608078. |
thus, mepeg-ssa-pcl exhibited a more potent antiepileptic effect than ssa in acute mouse epilepsy models and could alleviate neuronal damage in the hippocampus following epileptic seizures, possibly via gaba-a receptor expression upregulation. |
2023-08-22 |
2023-09-07 |
mouse |
| B Sklenarova, E Zatloukalova, J Cimbalnik, P Klimes, I Dolezalova, M Pail, J Kocvarova, M Hendrych, M Hermanova, J Gotman, F Dubeau, J Hall, R Pana, B Frauscher, M Brazdi. Interictal High-Frequency Oscillations, Spikes, and Connectivity Profiles: a Fingerprint of Epileptogenic Brain Pathologies. Epilepsia. 2023-08-18. PMID:37592755. |
focal cortical dysplasia (fcd), hippocampal sclerosis (hs), nonspecific gliosis (ng), and normal tissue (nt) comprise the majority of histopathological results of surgically treated drug-resistant epilepsy patients. |
2023-08-18 |
2023-09-07 |
Not clear |
| Ali Pourmotabbed, Razieh Naghizadeh, Farshad Moradpour, Mozhgan Veisi, Seyed Ershad Nedaei, Fatemeh Zarei, Zahra Salim. The effects of kindling during pregnancy on long-term potentiation (LTP) induction and M Research in pharmaceutical sciences. vol 18. issue 3. 2023-08-18. PMID:37593163. |
the effects of kindling during pregnancy on long-term potentiation (ltp) induction and m neonates of pregnant women with epilepsy may compromise normal neurodevelopment and hippocampal morphology. |
2023-08-18 |
2023-09-07 |
Not clear |
| Marisol Soula, Anna Maslarova, Ryan E Harvey, Manuel Valero, Sebastian Brandner, Hajo Hamer, Antonio Fernández-Ruiz, György Buzsák. Interictal epileptiform discharges affect memory in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 34. 2023-08-17. PMID:37590406. |
understanding the role ieds have on the hippocampal circuit is important for our understanding of the cognitive deficits seen in epilepsy and ad. |
2023-08-17 |
2023-09-07 |
mouse |
| Marisol Soula, Anna Maslarova, Ryan E Harvey, Manuel Valero, Sebastian Brandner, Hajo Hamer, Antonio Fernández-Ruiz, György Buzsák. Interictal epileptiform discharges affect memory in an Alzheimer's disease mouse model. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 34. 2023-08-17. PMID:37590406. |
we characterize and compare the ieds of human epilepsy patients from microwire hippocampal recording with those of ad transgenic mice with implanted multilayer hippocampal silicon probes. |
2023-08-17 |
2023-09-07 |
mouse |
| Griffin Rodgers, Christos Bikis, Philipp Janz, Christine Tanner, Georg Schulz, Peter Thalmann, Carola A Haas, Bert Mülle. 3D X-ray Histology for the Investigation of Temporal Lobe Epilepsy in a Mouse Model. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2023-08-16. PMID:37584515. |
the most common form of epilepsy among adults is mesial temporal lobe epilepsy (mtle), with seizures often originating in the hippocampus due to abnormal electrical activity. |
2023-08-16 |
2023-09-07 |
mouse |
| Wesley Clawson, Benjamin Waked, Tanguy Madec, Antoine Ghestem, Pascale P Quilichini, Demian Battaglia, Christophe Bernar. Perturbed information processing complexity in experimental epilepsy. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-08-07. PMID:37550052. |
here, we test the hypothesis that primitive processes of information processing at the core of cognitive function - storage and sharing of information - are altered in the hippocampus and the entorhinal cortex in experimental epilepsy in adult, male wistar rats. |
2023-08-07 |
2023-08-14 |
rat |
| Laura de Diego-Garcia, Gary P Brennan, Theresa Auer, Aida Menendez-Mendez, Alberto Parras, Alba Martin-Gil, Meghma Mitra, Ivana Ollà, Leticia Villalba-Benito, Beatriz Gil, Mariana Alves, Kelvin Lau, Norman Delanty, Alan Beausang, Jane Cryan, Francesca M Brett, Michael A Farrell, Donncha F O'Brien, Raúl Mendez, Gonzalo Carracedo-Rodríguez, David C Henshall, José J Lucas, Tobias Enge. CPEB4 - CLOCK crosstalk during temporal lobe epilepsy. Epilepsia. 2023-08-06. PMID:37543852. |
previous studies have shown large-scale changes in mrna polyadenylation in the hippocampus of mice during epilepsy development. |
2023-08-06 |
2023-08-14 |
mouse |
| Shuang Peng, Xuling Wu, Qian Zheng, Jianwei Xu, Dongjun Xie, Mengyun Zhou, Mingwei Wang, Yongran Cheng, Lan Ye, Xiangang Mo, Zhanhui Fen. Downregulating NHE-1 decreases the apoptosis of hippocampal cells in epileptic model rats based on the NHE-1/calpain1 pathway. Heliyon. vol 9. issue 7. 2023-08-04. PMID:37539113. |
seizure is associated with pathological changes of hippocampus, but the mechanism by which hippocampal neuronal apoptosis promotes epilepsy is unclear. |
2023-08-04 |
2023-08-14 |
rat |
| Elena A Filimonova, Anton A Pashkov, Galina I Moysak, Anastasia Y Tropynina, Svetlana Y Zhanaeva, Anna A Shvaikovskaya, Anna A Akopyan, Konstantin V Danilenko, Lyubomir I Aftanas, Maria A Tikhonova, Jamil A Rzae. Brain but not serum BDNF levels are associated with structural alterations in the hippocampal regions in patients with drug-resistant mesial temporal lobe epilepsy. Frontiers in neuroscience. vol 17. 2023-08-04. PMID:37539386. |
to narrow this gap, in this study, we aimed to estimate the relationship between hippocampal and serum levels of brain-derived neurotrophic factor (bdnf), one of the main and most widely studied neurotrophins, and hippocampal subfield volumes in patients with drug-resistant mesial temporal epilepsy undergoing neurosurgical treatment. |
2023-08-04 |
2023-08-14 |
human |
| Merve Aktan Suzgun, Huseyin Mert Cerci, Cihan Isler, Lebriz Uslu-Besli, Mustafa Uzan, Cigdem Ozkar. A medically-refractory epilepsy case with discordant pre-surgical findings: the pitfall of burned-out hippocampus. Epileptic disorders : international epilepsy journal with videotape. 2023-07-31. PMID:37518901. |
a medically-refractory epilepsy case with discordant pre-surgical findings: the pitfall of burned-out hippocampus. |
2023-07-31 |
2023-08-14 |
Not clear |
| Qian Yi Ooi, Xiaoya Qin, Yuan Yuan, Xiaobin Zhang, Yi Yao, Hongwei Hao, Luming L. Alteration of Excitation/Inhibition Imbalance in the Hippocampus and Amygdala of Drug-Resistant Epilepsy Patients Treated with Acute Vagus Nerve Stimulation. Brain sciences. vol 13. issue 7. 2023-07-29. PMID:37508908. |
alteration of excitation/inhibition imbalance in the hippocampus and amygdala of drug-resistant epilepsy patients treated with acute vagus nerve stimulation. |
2023-07-29 |
2023-08-14 |
Not clear |
| Qian Yi Ooi, Xiaoya Qin, Yuan Yuan, Xiaobin Zhang, Yi Yao, Hongwei Hao, Luming L. Alteration of Excitation/Inhibition Imbalance in the Hippocampus and Amygdala of Drug-Resistant Epilepsy Patients Treated with Acute Vagus Nerve Stimulation. Brain sciences. vol 13. issue 7. 2023-07-29. PMID:37508908. |
using stereo-electroencephalography (seeg) data, we examined the e/i imbalance in the hippocampus and amygdala of ten drug-resistant epilepsy children treated with acute vagus nerve stimulation (vns) by estimating the 1/f power slope of hippocampal and amygdala signals in the range of 1-80 hz. |
2023-07-29 |
2023-08-14 |
Not clear |