Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Tae-Cheon Kan. Distinct Roles of CK2- and AKT-Mediated NF-κB Phosphorylations in Clasmatodendrosis (Autophagic Astroglial Death) within the Hippocampus of Chronic Epilepsy Rats. Antioxidants (Basel, Switzerland). vol 12. issue 5. 2023-05-27. PMID:37237886. |
distinct roles of ck2- and akt-mediated nf-κb phosphorylations in clasmatodendrosis (autophagic astroglial death) within the hippocampus of chronic epilepsy rats. |
2023-05-27 |
2023-08-14 |
rat |
Ji-Eun Kim, Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Tae-Cheon Kan. Distinct Roles of CK2- and AKT-Mediated NF-κB Phosphorylations in Clasmatodendrosis (Autophagic Astroglial Death) within the Hippocampus of Chronic Epilepsy Rats. Antioxidants (Basel, Switzerland). vol 12. issue 5. 2023-05-27. PMID:37237886. |
the downregulation of glutathione peroxidase-1 (gpx1) plays a role in clasmatodendrosis (an autophagic astroglial death) in the hippocampus of chronic epilepsy rats. |
2023-05-27 |
2023-08-14 |
rat |
Jin Li, Dan Cao, Shan Yu, Xinyu Xiao, Lukas Imbach, Lennart Stieglitz, Johannes Sarnthein, Tianzi Jian. Functional specialization and interaction in the amygdala-hippocampus circuit during working memory processing. Nature communications. vol 14. issue 1. 2023-05-22. PMID:37217494. |
here, we simultaneously recorded intracranial eeg from the amygdala and hippocampus of epilepsy patients while performing a wm task, and compared their representation patterns during the encoding and maintenance periods. |
2023-05-22 |
2023-08-14 |
Not clear |
Kishore Madhamanchi, Pradeep Madhamanchi, Sita Jayalakshmi, Manas Panigrahi, Anuja Patil, Prakash Babu Phanith. Dopamine and Glutamate Crosstalk Worsen the Seizure Outcome in TLE-HS Patients. Molecular neurobiology. 2023-05-20. PMID:37209264. |
temporal lobe epilepsy (tle), accompanied by hippocampal sclerosis (hs), is the most common form of drug-resistant epilepsy (dre). |
2023-05-20 |
2023-08-14 |
Not clear |
Michelle C Gulfo, Joseph J Lebowitz, Czarina Ramos, Dong-Woo Hwang, Kaoutsar Nasrallah, Pablo E Castill. Dopamine D2 receptors in mossy cells reduce excitatory transmission and are essential for hippocampal function. bioRxiv : the preprint server for biology. 2023-05-19. PMID:37205586. |
hilar mossy cells (mcs) are principal excitatory neurons of the dentate gyrus (dg) that play critical roles in hippocampal function and have been implicated in brain disorders such as anxiety and epilepsy. |
2023-05-19 |
2023-08-14 |
Not clear |
Yihan Zhao, Wenying Zhao, Ying Ha. Inhibition of mTORC2 improves brain injury in epileptic rats by promoting chaperone-mediated autophagy. Epilepsy research. vol 193. 2023-05-10. PMID:37163909. |
our research results show that the levels of apoptosis in cortical and hippocampal neurons were upregulated in epileptic rats (f = 32.15, 30.96; both p < 0.01), and epilepsy caused neuronal damage (f = 8.13, 9.43; both p < 0.01). |
2023-05-10 |
2023-08-14 |
rat |
Bárður H Joensen, Daniel Bush, Umesh Vivekananda, Aidan J Horner, James A Bisby, Beate Diehl, Anna Miserocchi, Andrew W McEvoy, Matthew C Walker, Neil Burges. Hippocampal theta activity during encoding promotes subsequent associative memory in humans. Cerebral cortex (New York, N.Y. : 1991). 2023-05-09. PMID:37160345. |
here we asked 10 pre-surgical epilepsy patients undergoing intracranial electroencephalography recording, along with 21 participants undergoing magnetoencephalography recordings, to perform an associative memory task, and examined whether hippocampal theta activity during encoding was predictive of subsequent associative memory performance. |
2023-05-09 |
2023-08-14 |
human |
Jiali Liu, Dong Chen, Xue Xiao, Hui Zhang, Wenjing Zhou, Shuli Liang, Lukas Kunz, Andreas Schulze-Bonhage, Nikolai Axmacher, Liang Wan. Multi-scale goal distance representations in human hippocampus during virtual spatial navigation. Current biology : CB. 2023-05-06. PMID:37148875. |
using intracranial eeg recordings from the hippocampus of drug-resistant epilepsy patients who performed a virtual spatial navigation task, we found that the right hippocampal theta power was significantly modulated by goal distance and decreased with goal proximity. |
2023-05-06 |
2023-08-14 |
human |
Guoli Zhang, Ying Gao, Lixin Jiang, Yuhang Zhan. LncRNA FTX inhibits ferroptosis of hippocampal neurons displaying epileptiform discharges in vitro through the miR-142-5p/GABPB1 axis. Neuroscience. 2023-04-30. PMID:37121382. |
hippocampal neurons were isolated from brain tissues of healthy male sd rats, and an in vitro cell model of epilepsy was established using magnesium-free (mgf) induction. |
2023-04-30 |
2023-08-14 |
rat |
Mao-Qiang Tian, Juan Li, Xiao-Mei Shu, Chang-Hui Lang, Jing Chen, Long-Ying Peng, Wen-Ting Lei, Chang-Jian Yan. The increase of Nrf2 m6A modification induced by FTO downregulation promotes hippocampal neuron injury and aggravates the progression of epilepsy in a rat model. Synapse (New York, N.Y.). 2023-04-30. PMID:37122072. |
the increase of nrf2 m6a modification induced by fto downregulation promotes hippocampal neuron injury and aggravates the progression of epilepsy in a rat model. |
2023-04-30 |
2023-08-14 |
rat |
Ali Tayebi Meybodi, Giancarlo Mignucci-Jiménez, Yuan Xu, Mark C Preu. Artery of Uchimura: origin and evolution of identification of the vascular supply to the hippocampus. Journal of neurosurgery. 2023-04-22. PMID:37086167. |
uchimura's description of hippocampal vasculature, which is still subject to debate after nearly a century, brought international attention to ahs and epilepsy and showed the hippocampal vasculature to be variable and vulnerable; important considerations for later neurosurgeons in the development of selective mesial temporal surgery. |
2023-04-22 |
2023-08-14 |
human |
Matteo Egger, Wenshu Luo, Natalia Cruz-Ochoa, David Lukacsovich, Csaba Varga, Lin Que, Gyula Maloveczky, Jochen Winterer, Rashmit Kaur, Tamás Lukacsovich, Csaba Föld. Commissural dentate granule cell projections and their rapid formation in the adult brain. PNAS nexus. vol 2. issue 4. 2023-04-20. PMID:37077887. |
in this model, commissural gc axon growth appears together with the well-studied hippocampal mossy fiber sprouting and may be important for the pathomechanisms of epilepsy. |
2023-04-20 |
2023-08-14 |
mouse |
Juri-Alexander Witt, Albert J Becker, Christoph Helmstaedte. The multifactorial etiology of cognitive deficits in epilepsy and the neuropathology of mesial temporal lobe epilepsy beyond hyperphosphorylated tau. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-04-18. PMID:37070290. |
in response to the recent review by zawar and kapur on the overlap between mesial temporal lobe epilepsy (mtle) and alzheimer's disease (ad), we (1) underscore that the bidirectionality between epilepsy and dementia is of high interest, also from the epileptological perspective; (2) outline the multifactorial etiology of cognitive deficits in epilepsy; (3) emphasize that the most prevalent neuropathological findings in mtle comprise hippocampal sclerosis, dysplastic lesions, and neurodevelopmental neoplasm; and (4) state that anti-seizure medication can also have adverse effects on cognition. |
2023-04-18 |
2023-08-14 |
Not clear |
Hu Zheng, Liuyang Wu, Huisheng Yua. miR-30b-5p targeting GRIN2A inhibits hippocampal damage in epilepsy. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-04-05. PMID:37016703. |
mir-30b-5p targeting grin2a inhibits hippocampal damage in epilepsy. |
2023-04-05 |
2023-08-14 |
mouse |
Ming-Jian Wang, Xue Liu, Song Chi, Fei-Yu Wang, Liang Zhang, Min-Yi Yao, Tao Liu, Jing Ga. Activation of PPARγ prevents ferroptosis-induced damage through Nrf2/Gpx4 signaling pathway in rat hippocampus following epilepsy. Neuroreport. vol 34. issue 6. 2023-04-03. PMID:37010494. |
activation of pparγ prevents ferroptosis-induced damage through nrf2/gpx4 signaling pathway in rat hippocampus following epilepsy. |
2023-04-03 |
2023-08-14 |
rat |
João Chaves, Bárbara Leal, Ana Sardoeira, Vanessa Carvalho, Raquel Samões, Joel Freitas, Rui Chorão, Ana Marta Ferreira, Sandra Brás, João Lopes, João Ramalheira, Carolina Lemos, Paulo Pinho Costa, António Marinho, Berta Martins da Silva, António Martins da Silv. Different relationships between epilepsy syndromes and autoimmune diseases. Epileptic disorders : international epilepsy journal with videotape. 2023-04-01. PMID:37002555. |
our objective was to study the relationship between epilepsy and autoimmune diseases in two different types of epilepsy: idiopathic generalized epilepsies (iges) and mesial temporal lobe epilepsy with hippocampal sclerosis (mtle-hs). |
2023-04-01 |
2023-08-14 |
human |
Feng-Lin Tang, Xiao-Gang Zhang, Ping-Yang Ke, Jie Liu, Zhi-Juan Zhang, Dan-Mei Hu, Juan Gu, Hui Zhang, Hao-Kun Guo, Qian-Wen Zang, Rui Huang, Yuan-Lin Ma, Patrick Kwa. MBD5 regulates NMDA receptor expression and seizures by inhibiting Stat1 transcription. Neurobiology of disease. 2023-03-30. PMID:36997128. |
here, we found that mbd5 was mainly localized in the pyramidal cells and granular cells of mouse hippocampus, and its expression was increased in the brain tissues of mouse models of epilepsy. |
2023-03-30 |
2023-08-14 |
mouse |
Hongyuan Lu, Qinbiao Wang, Xiaowen Jiang, Yanyun Zhao, Miao He, Minjie We. The Potential Mechanism of Cannabidiol (CBD) Treatment of Epilepsy in Pentetrazol (PTZ) Kindling Mice Uncovered by Multi-Omics Analysis. Molecules (Basel, Switzerland). vol 28. issue 6. 2023-03-29. PMID:36985783. |
however, how cbd ameliorates epilepsy and its effect on the hippocampus remains unknown. |
2023-03-29 |
2023-08-14 |
mouse |
Hongyuan Lu, Qinbiao Wang, Xiaowen Jiang, Yanyun Zhao, Miao He, Minjie We. The Potential Mechanism of Cannabidiol (CBD) Treatment of Epilepsy in Pentetrazol (PTZ) Kindling Mice Uncovered by Multi-Omics Analysis. Molecules (Basel, Switzerland). vol 28. issue 6. 2023-03-29. PMID:36985783. |
in conclusion, cbd ameliorates epilepsy by acting on the metabolism, calcium signaling pathway, and tuberculosis pathways in the hippocampus. |
2023-03-29 |
2023-08-14 |
mouse |
Riju Dahal, Kentaro Tamura, Ryota Sasaki, Yasuhiro Takeshima, Ryosuke Matsuda, Shuichi Yamada, Fumihiko Nishimura, Ichiro Nakagawa, Young-Soo Park, Hiroyuki Nakas. Left Temporal Pole Encephalocele With Independent Hippocampal Seizures: Surgical Strategy and Relevance of Epileptic Biomarkers. Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society. 2023-03-17. PMID:36930243. |
a 27-year-old patient presented with medically intractable epilepsy because of a left temporal pole encephalocele with a normal hippocampus on mri. |
2023-03-17 |
2023-08-14 |
Not clear |