| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Xue Xu, Rui-Xue Shi, Yu Fu, Jia-Lu Wang, Xin Tong, Shi-Qi Zhang, Na Wang, Mei-Xuan Li, Yu Tong, Wei Wang, Miao He, Bing-Yang Liu, Gui-Lan Chen, Feng Gu. Neuronal nitric oxide synthase/reactive oxygen species pathway is involved in apoptosis and pyroptosis in epilepsy. Neural regeneration research. vol 18. issue 6. 2022-12-01. PMID:36453412. |
in this study, we performed rna sequencing, functional enrichment analysis, and weighted gene coexpression network analysis of the hippocampus of tremor rats, a rat model of genetic epilepsy. |
2022-12-01 |
2023-08-14 |
rat |
| Nicola Masala, Martin Pofahl, André N Haubrich, Khondker Ushna Sameen Islam, Negar Nikbakht, Maryam Pasdarnavab, Kirsten Bohmbach, Kunihiko Araki, Fateme Kamali, Christian Henneberger, Kurtulus Golcuk, Laura A Ewell, Sandra Blaess, Tony Kelly, Heinz Bec. Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy. Brain : a journal of neurology. 2022-11-30. PMID:36448426. |
two-photon glutamate uncaging experiments revealed a marked increase in the fraction of hippocampal 1st order ca1 pyramidal cell dendrites capable of generating dendritic spikes in the kainate model of chronic epilepsy. |
2022-11-30 |
2023-08-14 |
mouse |
| Ana Gonzalez-Ramos, Kerstin Laurin, Fredrik Berglind, Marco Ledri, Merab Kokaia, My Andersso. Transplantation of Human Stem Cell-Derived GABAergic Neurons into the Early Postnatal Mouse Hippocampus to Mitigate Neurodevelopmental Disorders. Journal of visualized experiments : JoVE. issue 189. 2022-11-28. PMID:36440838. |
the transplanted neurons disperse in the ipsi- and contralateral hippocampus of a mouse model of cortical dysplasia-focal epilepsy syndrome and survive for up to 9 months after transplantation. |
2022-11-28 |
2023-08-14 |
mouse |
| Evgenia Sitnikova, Dmitrii Perevozniuk, Elizaveta Rutskova, Shukhrat Uzakov, Viktor A Korshuno. Reduction of Hippocampal High-Frequency Activity in Wag/Rij Rats with a Genetic Predisposition to Absence Epilepsy. Diagnostics (Basel, Switzerland). vol 12. issue 11. 2022-11-26. PMID:36428857. |
in contrast, absence epilepsy and other idiopathic epilepsies are known to result from thalamo-cortical abnormalities, with the hippocampus involvement considered to be only indirect. |
2022-11-26 |
2023-08-14 |
rat |
| Expression of Concern: Down-regulated microRNA-183 mediates the Jak/Stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting Foxp1. Cell cycle (Georgetown, Tex.). 2022-11-25. PMID:36426649. |
expression of concern: down-regulated microrna-183 mediates the jak/stat signaling pathway to attenuate hippocampal neuron injury in epilepsy rats by targeting foxp1. |
2022-11-25 |
2023-08-14 |
rat |
| Antje Kilias, Susanne Tulke, Nicole Barheier, Patrick Ruther, Ute Häussle. Integration of the CA2 region in the hippocampal network during epileptogenesis. Hippocampus. 2022-11-24. PMID:36421040. |
furthermore, they show increased excitability in vitro in hippocampal slices obtained from human mtle specimens or animal epilepsy models. |
2022-11-24 |
2023-08-14 |
mouse |
| Macarena S Aloi, Samantha J Thompson, Nicholas Quartapella, Jeffrey L Noebel. Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice. Cell reports. vol 41. issue 8. 2022-11-23. PMID:36417872. |
mutations in kv1.1 (kcna1) voltage-gated potassium channels in humans and mice generate network hyperexcitability, enhancing aberrant postnatal neurogenesis in the dentate subgranular zone, resulting in epilepsy and hippocampal hypertrophy. |
2022-11-23 |
2023-08-14 |
mouse |
| Macarena S Aloi, Samantha J Thompson, Nicholas Quartapella, Jeffrey L Noebel. Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice. Cell reports. vol 41. issue 8. 2022-11-23. PMID:36417872. |
here, we find that the functional unit of sxc, xct (slc7a11), is upregulated in regions of kcna1 knockout (ko) hippocampus, suggesting a contribution to both hyperplasia and epilepsy. |
2022-11-23 |
2023-08-14 |
mouse |
| Yong-Ge Li, Shu Zhou, Yin-le Yao, Xiao-Ming Wei, Shi-Feng Zhan. [The effects of vagus nerve stimulation on hippocampal neuro-inflammatory and α7nAChR expression in rats with intractable epilepsy]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 38. issue 4. 2022-11-22. PMID:36414564. |
[the effects of vagus nerve stimulation on hippocampal neuro-inflammatory and α7nachr expression in rats with intractable epilepsy]. |
2022-11-22 |
2023-08-14 |
rat |
| Satya S Sahoo, Katja Kobow, Jianzhe Zhang, Jeffrey Buchhalter, Mojtaba Dayyani, Dipak P Upadhyaya, Katrina Prantzalos, Meenakshi Bhattacharjee, Ingmar Blumcke, Samuel Wiebe, Samden D Lhato. Ontology-based feature engineering in machine learning workflows for heterogeneous epilepsy patient records. Scientific reports. vol 12. issue 1. 2022-11-13. PMID:36371527. |
this cohort included 312 patients who underwent epilepsy surgery and were labeled with one or more diagnoses, including dual pathology, hippocampal sclerosis, malformation of cortical dysplasia, tumor, encephalitis, and gliosis. |
2022-11-13 |
2023-08-14 |
Not clear |
| Mariana de Souza Aranha Garcia-Gomes, Pedro Kenzo Yamamoto, Silvia Maria Gomes Massironi, Orfa Yineth Galvis-Alonso, Jorge Mejia, Dennis Albert Zanatto, Sandra Regina Alexandre-Ribeiro, Susan Ienne, Claudia Madalena Cabrera Mor. Alteration of hippocampal Egr3, GABA A receptors, Il-1β, Il6 and Ccl3 expression in audiogenic tremor mice after seizure. Epilepsy & behavior : E&B. vol 137. issue Pt A. 2022-11-10. PMID:36356419. |
in conclusion, overexpression of ccl3 in the hippocampus of naive tremor mice, followed by downregulation soon after seizure in stimulated tremor mice, could be involved in changes in the blood-brain barrier (bbb) permeability in epilepsy. |
2022-11-10 |
2023-08-14 |
mouse |
| Daisuke Hasegawa, Shinichi Kanazono, James K Chambers, Kazuyuki Uchid. Neurosurgery in feline epilepsy, including clinicopathology of feline epilepsy syndromes. Veterinary journal (London, England : 1997). 2022-11-08. PMID:36347391. |
furthermore, approximately 50% of cats with epileptic seizures are diagnosed with structural epilepsy with or without hippocampal abnormality and may respond to surgical intervention. |
2022-11-08 |
2023-08-14 |
Not clear |
| Lin Guo, Tianyu Gao, Xiaoxia Jia, Ce Gao, Hao Tian, Yaqin Wei, Wenchun Lu, Zhidong Liu, Yun Wan. SKF83959 Attenuates Memory Impairment and Depressive-like Behavior during the Latent Period of Epilepsy via Allosteric Activation of the Sigma-1 Receptor. ACS chemical neuroscience. 2022-11-04. PMID:36331871. |
we found that skf83959 ameliorated memory impairment and depressive-like mood, alleviated the neuron damage and the formation of gliosis in hippocampus, suppressed the rise of pro-inflammatory cytokines, including tumor necrosis factor-α and interleukin-1β, and induced nitric oxide synthase in the latent period of epilepsy. |
2022-11-04 |
2023-08-14 |
mouse |
| Rockelle S Guthrie, Davide Ciliberti, Emily A Mankin, Gina R Po. Recurrent Hippocampo-neocortical sleep-state divergence in humans. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 44. 2022-10-24. PMID:36279474. |
we analyzed sleep states independently from simultaneously recorded hippocampal depth electrodes and cortical scalp electrodes in eight human subjects who were implanted with depth electrodes for pharmacologically intractable epilepsy evaluation. |
2022-10-24 |
2023-08-14 |
human |
| Claire A Simeone, John P Andrews, Shawn P Johnson, Mariana Casalia, Ryan Kochanski, Edward F Chang, Dianne Cameron, Sophie Dennison, Ben Inglis, Gregory Scott, Kris Kruse-Elliott, F Fabian Okonski, Eric Calvo, Kelly Goulet, Dawn Robles, Ashley Griffin-Stence, Erin Kuiper, Laura Krasovec, Cara L Field, Vanessa F Hoard, Scott C Baraba. Xenotransplantation of porcine progenitor cells in an epileptic California sea lion (Zalophus californianus): illustrative case. Journal of neurosurgery. Case lessons. vol 3. issue 12. 2022-10-23. PMID:36273868. |
california sea lions exposed to da in prey during algal blooms along the pacific coast exhibit significant neurological symptoms, including epilepsy with hippocampal atrophy. |
2022-10-23 |
2023-08-14 |
Not clear |
| Andrea Romigi, Alfredo D'Aniello, Marco Caccamo, Federica Testa, Giuseppe Vitrani, Liliana Grammaldo, Marco De Risi, Sara Casciato, Simone Cappellano, Vincenzo Esposito, Diego Centonze, Giancarlo Di Gennar. Sleep macrostructure and cyclic alternating pattern in patients who underwent surgery for hippocampal sclerosis: A prospective controlled polysomnographic study. Sleep medicine. vol 100. 2022-10-16. PMID:36244316. |
temporal lobe epilepsy due to hippocampal sclerosis (tle-hs) is one of the most common drug-resistant epilepsy. |
2022-10-16 |
2023-08-14 |
Not clear |
| Bridget Martinez, Philip V Peplo. MicroRNAs as potential biomarkers in temporal lobe epilepsy and mesial temporal lobe epilepsy. Neural regeneration research. vol 18. issue 4. 2022-10-07. PMID:36204827. |
temporal lobe epilepsy is the most common form of focal epilepsy in adults, accounting for one third of all diagnosed epileptic patients, with seizures originating from or involving mesial temporal structures such as the hippocampus, and many of these patients being refractory to treatment with anti-epileptic drugs. |
2022-10-07 |
2023-08-14 |
mouse |
| Merran R Courtney, Ana Antonic-Baker, Benjamin Sinclair, John-Paul Nicolo, Andrew Neal, Meng Law, Patrick Kwan, Terence J O'Brien, Lucy Vivas. BMJ open. vol 12. issue 10. 2022-10-06. PMID:36202585. |
while some factors, such as the detection of hippocampal sclerosis or a resectable lesion on mri and electroencephalogram-mri concordance, can predict favourable outcomes in epilepsy surgery, the prognostic value of the detection of focal hypometabolism with |
2022-10-06 |
2023-08-14 |
Not clear |
| Alfredo Lucas, Ravi Prakash Reddy Nanga, Peter Hadar, Stephanie Chen, Adam Gibson, Kelly Oechsel, Mark A Elliott, Joel M Stein, Sandhitsu Das, Ravinder Reddy, John A Detre, Kathryn A Davi. Mapping hippocampal glutamate in mesial temporal lobe epilepsy with glutamate weighted CEST (GluCEST) imaging. Human brain mapping. 2022-09-29. PMID:36173151. |
overall, our results suggest that hippocampal glutamate mapping through glucest imaging is a valuable addition to the presurgical epilepsy evaluation toolbox. |
2022-09-29 |
2023-08-14 |
Not clear |
| Shrimanth Yamasandi Siddegowda, Renu Suthar, Pratibha Singhi, Chirag Ahuja, Niranjan K Khandelwal, Naveen Sankhya. Epilepsy Outcomes and Hippocampal Volumes in Children with Multiple Parenchymal Neurocysticercoses. Journal of pediatric neurosciences. vol 16. issue 3. 2022-09-26. PMID:36160608. |
epilepsy outcomes and hippocampal volumes in children with multiple parenchymal neurocysticercoses. |
2022-09-26 |
2023-08-14 |
Not clear |