| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jaime Fernandez Arias, Joseph Therriault, Stijn Servaes, Arthur C Macedo, Yi-Ting Wang, Nesrine Rahmouni, Kely Monica Quispialaya Socualaya, Etienne Aumont, Lydia Trudel, Seyyed Ali Hosseini, Brandon J Hall, Tevy Chan, Peter Kunach, Sulantha Mathotaarachchi, Paolo Vitali, Pedro Rosa-Net. Clinical Manifestations. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 20 Suppl 3. 2025-01-03. PMID:39750247. |
epilepsy studies have suggested an association between left hippocampal damage and verbal memory deficits, and between right hippocampal damage and visual memory deficits. |
2025-01-03 |
2025-01-05 |
Not clear |
| Norris C Talbot, James R Bridges, Patrick M Luther, Michael S Folse, Ben V Peco, Connor Galardo, Michael P C Minamyer, Ryan Diaz, Bryce Bonin, Roohi Katyal, Mostafa Hotait, Jamie Tom. Comparison of Deep Brain Stimulation of the Hippocampus to Thalamic Targets and Responsive Neurostimulation for Adult Intractable Epilepsy: A Systematic Review and Meta-Analysis. World neurosurgery. 2024-12-30. PMID:39736312. |
comparison of deep brain stimulation of the hippocampus to thalamic targets and responsive neurostimulation for adult intractable epilepsy: a systematic review and meta-analysis. |
2024-12-30 |
2025-01-02 |
Not clear |
| Norris C Talbot, James R Bridges, Patrick M Luther, Michael S Folse, Ben V Peco, Connor Galardo, Michael P C Minamyer, Ryan Diaz, Bryce Bonin, Roohi Katyal, Mostafa Hotait, Jamie Tom. Comparison of Deep Brain Stimulation of the Hippocampus to Thalamic Targets and Responsive Neurostimulation for Adult Intractable Epilepsy: A Systematic Review and Meta-Analysis. World neurosurgery. 2024-12-30. PMID:39736312. |
this study serves as a comprehensive analysis of dbs of the anterior nucleus of the thalamus (ant), centromedian thalamic nucleus (cmt), and hippocampus and rns for seizure reduction in adult intractable epilepsy. |
2024-12-30 |
2025-01-02 |
Not clear |
| Di Xia, Linming Zhang, Rong Mei, Chunhua Wu, Yan Liu, Hongyu Chen, Ling Che. Increased Expression of MST1 in Patients With Epilepsy and in a Rat Model of Epilepsy. Synapse (New York, N.Y.). vol 79. issue 1. 2024-12-27. PMID:39729046. |
after creation of epilepsy models with healthy male sprague-dawley rats using lithium and pilocarpine, the expression of mst1 in the temporal cortex and hippocampus was evaluated at different time points (6 h, 24 h, 3 days, 7 days, 14 days, and 30 days after seizures) using immunofluorescence, immunohistochemistry, and western blotting. |
2024-12-27 |
2024-12-29 |
rat |
| Xianglei Jia, Jian Xu, Yan Zhang, Shuo Kong, Xuelei Cheng, Ningyang Wu, Song Han, Jun Yin, Wanhong Liu, Xiaohua He, Yuanteng Fan, Yumin Liu, Taoxiang Chen, Biwen Pen. Elevated Astrocytic NFAT5 of the hippocampus increases epilepsy susceptibility in hypoxic-ischemic mice. Epilepsia. 2024-12-26. PMID:39724278. |
elevated astrocytic nfat5 of the hippocampus increases epilepsy susceptibility in hypoxic-ischemic mice. |
2024-12-26 |
2024-12-29 |
mouse |
| Jiaxin Li, Shuai Liu, Chenghan Chen, Jiahong Deng, Zibo Du, Simin Yang, Hongying Deng, Zhixia Zhang, Yiyu Huang, Jingwen Fu, Wangming Zhang, Wai Sang Poon, Honghao Hou, Jun Wan. The Epileptiogenic Modified Therapy: Regulating the Dynamic of Microglia via ROS-Responsive Cascade Nano-Formulation. Advanced healthcare materials. 2024-12-23. PMID:39713896. |
in the kainic acid (ka) epilepsy model, microglial processes elongate, branching increases, and interactions between microglia and neurons are strengthened in the ca1 and ca3 regions of the hippocampus compared to the vehicle group. |
2024-12-23 |
2024-12-25 |
Not clear |
| Emma Acerbo, Florian Missey, Adam S Dickey, Jan Trajlinek, Ondřej Studnička, Claudia Lubrano, Mariane de Araújo E Silva, Evan Brady, Vit Všianský, Johanna Szabo, Irena Dolezalova, Daniel Fabo, Martin Pail, Claire-Anne Gutekunst, Rosanna Migliore, Michele Migliore, Stanislas Lagarde, Romain Carron, Fariba Karimi, Raul Castillo Astorga, Antonino M Cassara, Niels Kuster, Esra Neufeld, Fabrice Bartolomei, Nigel P Pedersen, Robert E Gross, Viktor Jirsa, Daniel L Drane, Milan Brázdil, Adam Williamso. Non-invasive Temporal Interference Stimulation of the Hippocampus Suppresses Epileptic Biomarkers in Patients with Epilepsy: Biophysical Differences between Kilohertz and Amplitude Modulated Stimulation. medRxiv : the preprint server for health sciences. 2024-12-23. PMID:39711722. |
non-invasive temporal interference stimulation of the hippocampus suppresses epileptic biomarkers in patients with epilepsy: biophysical differences between kilohertz and amplitude modulated stimulation. |
2024-12-23 |
2024-12-25 |
Not clear |
| Emma Acerbo, Florian Missey, Adam S Dickey, Jan Trajlinek, Ondřej Studnička, Claudia Lubrano, Mariane de Araújo E Silva, Evan Brady, Vit Všianský, Johanna Szabo, Irena Dolezalova, Daniel Fabo, Martin Pail, Claire-Anne Gutekunst, Rosanna Migliore, Michele Migliore, Stanislas Lagarde, Romain Carron, Fariba Karimi, Raul Castillo Astorga, Antonino M Cassara, Niels Kuster, Esra Neufeld, Fabrice Bartolomei, Nigel P Pedersen, Robert E Gross, Viktor Jirsa, Daniel L Drane, Milan Brázdil, Adam Williamso. Non-invasive Temporal Interference Stimulation of the Hippocampus Suppresses Epileptic Biomarkers in Patients with Epilepsy: Biophysical Differences between Kilohertz and Amplitude Modulated Stimulation. medRxiv : the preprint server for health sciences. 2024-12-23. PMID:39711722. |
thirteen patients with symptoms of mesiotemporal epilepsy (mtle) and implanted with stereoelectroencephalography (seeg) depth electrodes received ti stimulation with an amplitude modulation (am) frequency of 130hz (Δf), where the am was delivered with lower frequency khz carriers (1khz + 1.13khz), or higher frequency carriers (9khz + 9.13khz), targeting the hippocampus - a common epileptic focus and consequently stimulation target in mtle. |
2024-12-23 |
2024-12-25 |
Not clear |
| Suvasini Sharma, Robyn Whitney, Sayoni Roy Chowdhury, Rajesh Ramachandrannai. Sudden unexpected infant death, sudden unexplained death in childhood, and sudden unexpected death in epilepsy. Developmental medicine and child neurology. 2024-12-22. PMID:39709626. |
common features include death occurring during sleep, discovery in the prone position, hippocampal abnormalities, and genetic variations associated with epilepsy or cardiac arrhythmias. |
2024-12-22 |
2024-12-25 |
Not clear |
| Seung Ho Choo, Hea Ree Park, Seunghoon Lee, Jung-Il Lee, Eun Yeon Joo, Dae-Won Seo, Seung Bong Hong, Young-Min Sho. Hippocampal deep brain stimulation for drug-resistant epilepsy: Insights from bilateral temporal lobe and posterior epilepsy cases. Seizure. vol 124. 2024-12-11. PMID:39662128. |
hippocampal deep brain stimulation for drug-resistant epilepsy: insights from bilateral temporal lobe and posterior epilepsy cases. |
2024-12-11 |
2024-12-14 |
Not clear |
| Seung Ho Choo, Hea Ree Park, Seunghoon Lee, Jung-Il Lee, Eun Yeon Joo, Dae-Won Seo, Seung Bong Hong, Young-Min Sho. Hippocampal deep brain stimulation for drug-resistant epilepsy: Insights from bilateral temporal lobe and posterior epilepsy cases. Seizure. vol 124. 2024-12-11. PMID:39662128. |
this study evaluates the long-term efficacy of hippocampal deep brain stimulation (hip-dbs) in patients with drug-resistant epilepsy (dre), specifically focusing on bilateral temporal lobe epilepsy (btle) and posterior epilepsy (pe). |
2024-12-11 |
2024-12-14 |
Not clear |
| Katie Sokolowski, Judy Liu, Marcus S Delatte, Simon Authier, Owen McMaster, Brad Bolo. The Role of Neuropathology Evaluation in the Nonclinical Assessment of Seizure Liability. Toxicologic pathology. 2024-12-05. PMID:39633285. |
neuro-imaging may show a structural abnormality underlying seizures, such as focal cortical dysplasia or hippocampal sclerosis in patients with chronic epilepsy. |
2024-12-05 |
2024-12-07 |
Not clear |
| Jia-Qi Ma, Lu Wang, Yue Zhang, Yong-Qian Bian, Xiao-Peng Qu, Li-Jia Song, Chao Wang, Li Gao, Qi-Xing Fang, De-Chang Zhao, Liang-Liang Shen, Bei Li. Single-nucleus RNA sequencing-based construction of a hippocampal neuron atlas in mice with epileptic cognitive impairment. iScience. vol 27. issue 10. 2024-12-05. PMID:39635132. |
here, we utilized snrna-seq to characterize the transcriptomic changes in hippocampal neurons of drug-resistant epilepsy (dre) cognitive-impaired mice. |
2024-12-05 |
2024-12-07 |
mouse |
| Judith Eberhard, Lukas Henning, Lorenz Fülle, Konrad Knöpper, Jana Böhringer, Frederike J Graelmann, Lea Hänschke, Julia Kenzler, Frederic Brosseron, Michael T Heneka, Ana I Domingos, Stefanie Eyerich, Matthias Lochner, Heike Weighardt, Peter Bedner, Christian Steinhäuser, Irmgard Förste. Ablation of CCL17-positive hippocampal neurons induces inflammation-dependent epilepsy. Epilepsia. 2024-11-28. PMID:39607395. |
ablation of ccl17-positive hippocampal neurons induces inflammation-dependent epilepsy. |
2024-11-28 |
2024-11-30 |
mouse |
| Miao-Miao Tian, Gang Liu, Juan Du, Yue Liu, Wei Wei, Xiao-Bing Lan, Dong-Mei Hai, Lin Ma, Jian-Qiang Yu, Ning Li. Gentiopicroside Attenuates Lithium/Pilocarpine-Induced Epilepsy Seizures by Down-Regulating NR2B/CaMKII/CREB and TLR4/NF-κB Signaling Pathways in the Hippocampus of Mice. Pharmaceuticals (Basel, Switzerland). vol 17. issue 11. 2024-11-27. PMID:39598325. |
gentiopicroside attenuates lithium/pilocarpine-induced epilepsy seizures by down-regulating nr2b/camkii/creb and tlr4/nf-κb signaling pathways in the hippocampus of mice. |
2024-11-27 |
2024-11-29 |
mouse |
| Álvaro de Oliveira Franco, Matheus Bernardon Morillos, Martim Tobias Bravo Leite, Marino Muxfeldt Bianchin, Carolina Machado Torre. DHDDS-related epilepsy with hippocampal atrophy: a case report. Neurogenetics. vol 26. issue 1. 2024-11-22. PMID:39576357. |
dhdds-related epilepsy with hippocampal atrophy: a case report. |
2024-11-22 |
2024-11-24 |
Not clear |
| Alena Stasenko, Erik Kaestner, Adam Schadler, Evan Brady, Jonathan Rodriguez, Rebecca W Roth, Ezequiel Gleichgerrcht, Jonathan L Helm, Daniel L Drane, Carrie R McDonal. Exercise, memory, and the hippocampus: Uncovering modifiable lifestyle reserve factors in refractory epilepsy. Epilepsy & behavior reports. vol 28. 2024-11-18. PMID:39555495. |
exercise, memory, and the hippocampus: uncovering modifiable lifestyle reserve factors in refractory epilepsy. |
2024-11-18 |
2024-11-22 |
human |
| Jennifer M Yonan, Kevin D Chen, Tallie Z Baram, Oswald Stewar. PTEN deletion in the adult dentate gyrus induces epilepsy. Neurobiology of disease. 2024-11-15. PMID:39547478. |
pten-deletion provoked epilepsy was not associated with apparent hippocampal neuron death; supra-granular mossy fiber sprouting was observed in a few mice. |
2024-11-15 |
2024-11-18 |
mouse |
| Ricardo C Wainberg, William Alves Martins, Francine H de Oliveira, Eliseu Paglioli, Ricardo Paganin, Ricardo Soder, Rafael Paglioli, Thomas M Frigeri, Matteo Baldisseroto, André Palmin. Histopathological substrate of increased T2 signal in the anterior temporal lobe white matter in temporal lobe epilepsy associated with hippocampal sclerosis. Epilepsia. 2024-11-06. PMID:39503609. |
this study was undertaken to analyze the histology underlying increased t2 signal intensity (it2si) in anterior temporal lobe white matter (atlwm) epilepsy due to hippocampal sclerosis (tle/hs). |
2024-11-06 |
2024-11-08 |
Not clear |
| Ricardo Schmidt, Björn Welzel, Annika Merten, Hannah Naundorf, Wolfgang Lösche. Temporal development of seizure threshold and spontaneous seizures after neonatal asphyxia and the effect of prophylactic treatment with midazolam in rats. Experimental neurology. 2024-11-06. PMID:39505250. |
here we used a non-invasive, physiologically validated rat model of ba and acute neonatal seizures that mimics many features of ba and hie in human infants to study (i) the temporal development of epilepsy with spontaneous recurrent seizures (srs) in the weeks and months after the initial brain injury, (ii) alterations in seizure threshold and hippocampal eeg that may precede the onset of srs, and (iii) the effect of prophylactic treatment with midazolam. |
2024-11-06 |
2024-11-09 |
human |