| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luis Manssuer, Qiong Ding, Yashu Feng, Ruoqi Yang, Wei Liu, Bomin Sun, Shikun Zhan, Valerie Voo. Reward recalibrates rule representations in human amygdala and hippocampus intracranial recordings. Nature communications. vol 15. issue 1. 2024-11-04. PMID:39496589. |
here, we demonstrate the importance of the amygdala and hippocampus by recording local field potentials directly from these regions intracranially in human epilepsy patients. |
2024-11-04 |
2024-11-07 |
human |
| Rita Machaalani, Michael Rodriguez, Arunnjah Vivekanandaraja. Focal granule cell bilamination of the dentate gyrus-its prevalence across the human age spectrum and review of the literature. Journal of neuropathology and experimental neurology. 2024-10-29. PMID:39468770. |
using formalin-fixed, paraffin-embedded hippocampal sections, this retrospective postmortem study evaluated the prevalence of fgcb and other granule cell pathologies in infants (1-12 months of age, n = 16), children (4-10 years, n = 6), and adults (28-91 years, n = 15) with no known history of epilepsy or seizures. |
2024-10-29 |
2024-10-31 |
human |
| Yuzhang Chen, Brian Litt, Flavia Vitale, Hajime Takan. On-Demand Seizures Facilitate Rapid Screening of Therapeutics for Epilepsy. bioRxiv : the preprint server for biology. 2024-10-28. PMID:39464023. |
for example, in temporal lobe epilepsy, a type of epilepsy where seizures originate from limbic structures like the hippocampus, the main screening models are either based on acutely induced seizures in wild type, naïve animals or spontaneous seizures in chronically epileptic animals. |
2024-10-28 |
2024-10-30 |
mouse |
| Hsiang-Yu Yu, Cheng Jui Tsai, Tse-Hao Lee, Hsin Tung, Yen-Cheng Shih, Chien-Chen Chou, Cheng-Chia Lee, Po-Tso Lin, Syu-Jyun Pen. Machine learning localization to identify the epileptogenic side in mesial temporal lobe epilepsy. Magnetic resonance imaging. 2024-10-19. PMID:39426692. |
most atrophic hippocampi can be identified using mri based on standard epilepsy protocols; however, difficulties can arise in cases where sclerotic changes in the hippocampus are subtle or non-epilepsy-specific protocols have been implemented. |
2024-10-19 |
2024-10-22 |
Not clear |
| Yuan Gao, Limin Ma, Jinxian Yuan, Yunyi Huang, Yuenan Ban, Peng Zhang, Dandan Tan, Minxue Liang, Zhipeng Li, Chen Gong, Tao Xu, Xiaolan Yang, Yangmei Che. GLS2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons. CNS neuroscience & therapeutics. vol 30. issue 10. 2024-10-15. PMID:39404053. |
gls2 reduces the occurrence of epilepsy by affecting mitophagy function in mouse hippocampal neurons. |
2024-10-15 |
2024-10-17 |
mouse |
| Ratchaniporn Kongsui, Teera Chanmanee, Tichanon Promsrisuk, Lars Klimaschewski, Napatr Sriraksa, Jinatta Jittiwat, Sitthisak Thongron. Neuroprotective effects of pink lotus oil in kainic acid-induced epilepsy. Heliyon. vol 10. issue 18. 2024-10-09. PMID:39381248. |
this study aimed to explore the possible therapeutic effects of plo and its underlying mechanisms on kainic acid (ka)-induced oxidative stress and hippocampal cell death in a mouse model of epilepsy. |
2024-10-09 |
2024-10-11 |
mouse |
| Li-Qin Che, Zhen-Zhen Qu, Zhuo-Feng Mao, Qi Qiao, Kai-Ping Zhou, Li-Jing Jia, Wei-Ping Wan. Low-frequency rTMS Plays a Neuroprotective role in Pilocarpine-induced Status Epilepticus Rat Models Through the AMPAR GluA1-STIM-Ca Molecular neurobiology. 2024-10-09. PMID:39384697. |
an epilepsy cell model was then established by incubating rat hippocampal neurons with mg |
2024-10-09 |
2024-10-12 |
rat |
| Carolyn Twible, Rober Abdo, Chelsey Zhao, Qi Zhan. Hippocampal dentate granule cells in temporal lobe epilepsy: A morphometry and transcriptomic study. Neuropathology and applied neurobiology. vol 50. issue 5. 2024-10-08. PMID:39375854. |
to elucidate the role of the dg in mtle, we analysed hippocampal sclerosis (hs), no-hs, non-tle epilepsy control, and non-epilepsy control cohorts using morphometry and gene expression profiling techniques. |
2024-10-08 |
2024-10-10 |
Not clear |
| Marson Putra, Nikhil S Rao, Cara Gardner, Guanghao Liu, Jordan Trommater, Michael Bunney, Meghan Gage, Alexander G Bassuk, Marco Hefti, Gloria Lee, Thimmasettappa Thippeswam. Enhanced Fyn-tau and NR2B-PSD95 interactions in epileptic foci in experimental models and human epilepsy. Brain communications. vol 6. issue 5. 2024-10-02. PMID:39355003. |
hippocampal proximity ligation assay and co-immunoprecipitation revealed a sustained increase of fyn-tau and nr2b-psd95 complexes/binding in rat chronic epilepsy at 3 months post-status epilepticus. |
2024-10-02 |
2024-10-04 |
human |
| Zhipeng Li, Jing Wang, Chongyang Tang, Peng Wang, Peng Ren, Siyang Li, Liye Yi, Qiuyi Liu, Lili Sun, Kaizhou Li, Wencai Ding, Hongbo Bao, Lifen Yao, Meng Na, Guoming Luan, Xia Lian. Coordinated NREM sleep oscillations among hippocampal subfields modulate synaptic plasticity in humans. Communications biology. vol 7. issue 1. 2024-10-01. PMID:39354050. |
using human intracranial recordings from 25 epilepsy patients, we find that hippocampal subfields, including dg/ca3, ca1, and sub, all exhibit significant delta and spindle power during nrem sleep. |
2024-10-01 |
2024-10-04 |
human |
| Colin M McCrimmon, Daniel Toker, Marie Pahos, Kevin Lozano, Jack J Lin, Jack Parent, Andrew Tidball, Jie Zheng, László Molnár, Istvan Mody, Bennett G Novitch, Ranmal A Samarasingh. Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. bioRxiv : the preprint server for biology. 2024-09-16. PMID:39282353. |
modeling cortical versus hippocampal network dysfunction in a human brain assembloid model of epilepsy and intellectual disability. |
2024-09-16 |
2024-09-19 |
human |
| Colin M McCrimmon, Daniel Toker, Marie Pahos, Kevin Lozano, Jack J Lin, Jack Parent, Andrew Tidball, Jie Zheng, László Molnár, Istvan Mody, Bennett G Novitch, Ranmal A Samarasingh. Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. bioRxiv : the preprint server for biology. 2024-09-16. PMID:39282353. |
for instance, a genetic epilepsy syndrome might cause seizures due to cortical hyperexcitability and present with memory impairments arising from hippocampal dysfunction. |
2024-09-16 |
2024-09-19 |
human |
| David A Narvaiz, Katherine J Blandin, D Gregory Sullens, Paige D Womble, Jacob B Pilcher, Grace O'Neill, Taylor A Wiley, Eliesse M Kwok, Srikhar V Chilukuri, Joaquin N Lug. NS-Pten knockout mice exhibit sex and hippocampal subregion-specific increases in microglia/macrophage density. Epilepsy research. vol 206. 2024-08-30. PMID:39213710. |
seizures induce hippocampal subregion dependent enhancements in microglia/macrophage phagocytosis and cytokine release that may contribute to the development of epilepsy. |
2024-08-30 |
2024-09-04 |
mouse |
| Yuchen Xu, Lily Zhang, Yan Yan, Wenbiao Xiao, Wei Zou, Zhaohui Luo, Bo Xiao, Hongyu Lon. MicroRNA-33 regulates the Synaptic Plasticity-related Gene ARC in Temporal Lobe Epilepsy. Neuroscience research. 2024-08-30. PMID:39214315. |
this study aimed to elucidate the expression patterns of mir-33 and arc in both a rat model of temporal lobe epilepsy (tle) and human tle patients, to explore the role of mir-33 in epilepsy onset through its regulation of arc expression in the hippocampus. |
2024-08-30 |
2024-09-04 |
human |
| M Christianne Hoeberigs, Jan C Beckervordersandforth, G de Bruyn, S Klinkenberg, O E M G Schijn. A teenage girl with drug-resistant epilepsy and a hippocampal angiocentric neuroepithelial tumor (ANET) - illustrative case of 7T MRI in clinical practice. Seizure. vol 121. 2024-08-24. PMID:39181014. |
a teenage girl with drug-resistant epilepsy and a hippocampal angiocentric neuroepithelial tumor (anet) - illustrative case of 7t mri in clinical practice. |
2024-08-24 |
2024-08-28 |
Not clear |
| Adebayo Adeyeye, Sara Mirsadeghi, Maryfer Gutierrez, Jenny Hsie. Integrating adult neurogenesis and human brain organoid models to advance epilepsy and associated behavioral research. Epilepsy & behavior : E&B. vol 159. 2024-08-24. PMID:39181108. |
while in vivo models provide valuable insights into some aspects of epileptogenesis, such as the impact of adult neurogenesis on hippocampal function, brain organoids are indispensable for comprehensively studying epileptogenesis involving genetic mutations that underlie human epilepsy. |
2024-08-24 |
2024-08-28 |
human |
| Lydia Wheeler, Samuel E Worrell, Irena Balzekas, Jordan Bilderbeek, Dora Hermes, Paul Croarkin, Steven Messina, Jamie Van Gompel, Kai J Miller, Vaclav Kremen, Gregory A Worrel. Case report: Bridging limbic network epilepsy with psychiatric, memory, and sleep comorbidities: case illustrations of reversible psychosis symptoms during continuous, high-frequency ANT-DBS. Frontiers in network physiology. vol 4. 2024-08-23. PMID:39175607. |
the network nature of focal epilepsy is exemplified by mesial temporal lobe epilepsy (mtle), characterized by focal seizures originating from the mesial temporal neocortex, amygdala, and hippocampus. |
2024-08-23 |
2024-08-25 |
Not clear |
| Yafu Tan, Yongjia Yu, Haodong Niu, Chunxi Wang, Panlin Mo, Dongqiao Li, Qing Zhang, Daqin Feng, Chang Li. Profile of miRNA expression in the hippocampus of epileptic mice and the prediction of potential therapeutic targets. Molecular biology reports. vol 51. issue 1. 2024-08-22. PMID:39172288. |
in this study, we established a lithium chloride-pilocarpine epilepsy mouse model, performed mirna sequencing of hippocampal tissue samples, and compared the obtained mirna expression profile with that of normal control mice to determine differences in expression levels. |
2024-08-22 |
2024-08-24 |
mouse |
| Maria Giardino, Francesca Peluso, Omar Daolio, Melissa Bellini, Enrico Ambrosini, Matteo Zito, Antonella Squarci. An uncommon neuroradiological finding of hippocampal malrotation in childhood onset schizophrenia and 22q11.2 Deletion Syndrome: a case report and a brief review of the literature. European child & adolescent psychiatry. 2024-08-20. PMID:39164503. |
while abnormalities of white matter and corpus callosum are associated with schizophrenia in patients with 22q11.2 deletion syndrome, hippocampal malrotation is more frequently described in patients with epilepsy and prolonged febrile seizures. |
2024-08-20 |
2024-08-23 |
Not clear |
| Maria Giardino, Francesca Peluso, Omar Daolio, Melissa Bellini, Enrico Ambrosini, Matteo Zito, Antonella Squarci. An uncommon neuroradiological finding of hippocampal malrotation in childhood onset schizophrenia and 22q11.2 Deletion Syndrome: a case report and a brief review of the literature. European child & adolescent psychiatry. 2024-08-20. PMID:39164503. |
recently, only 10 adult patients with 22q11.2 deletion syndrome have been reported to have hippocampal malrotation, six of whom were affected by schizophrenia, with or without epilepsy. |
2024-08-20 |
2024-08-23 |
Not clear |